iBB

The book G Protein-Coupled Receptor Screening Assays: Methods and Protocols, edited by Sofia Martins from INESC-MN and Miguel Prazeres from BERG-iBB, has just been published. This fully updated edition targets not only those assays directly involved in the discovery of GPCR-active compounds but also those involved in cell-based experiments designed to study physiological responses. Whether coming from academia or industry, or being an experienced researcher or a newcomer to the field, the reader will find accessible methods and protocols that cover the latest developments on receptor purification, molecular biology, recombinant engineering, and analytical techniques that enable the real time monitoring of the complex GPCR signaling cascade and identification of potential drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

The book "Yeasts in Biotechnology and Human Health", edited by Isabel Sá-Correia from BSRG-iBB and featuring contributions from international researchers has just been released by Springer. The book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research.

The book "Microbial Infections and Cancer Therapy", co-edited by Arsénio Fialho from BSRG-iBB in collaboration with Ananda Chakrabarty (University of Illinois) has just been released by Pan Stanford Publishing. The book deals with the emerging concept that certain pathogenic bacteria and viruses, when infecting people with cancer, actively fight tumors, allowing their regression. It features 12 chapters written by pioneers in microbial, biotech, and cancer research and covers the emerging roles of various microorganisms and their products in cancer therapy. The book highlights the benefits of using conventional cancer treatments (such as chemo- and radiotherapies) with microbial-based therapies.

The book G Protein Coupled Receptor Screening Assays: Methods and Protocols, edited by BERG-IBB researchers Sofia Martins and Miguel Prazeres, has just been published. The book reaches out to everyone involved in the discovery of GPCR-active drugs, and provides a transversal overview of the different levels of GPCR signaling addressable in the different screening strategies and presents practical examples of how current assay technologies are contributing to new paradigms in GPCR drug research. The book stems from the posto-doctoral work of Sofia Martins and features contributions from renowed specialists in the area. Click on title to learn more.