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How to Build an Artificial Heart

How to Build an Artificial Heart | healthcare technology | Scoop.it

Millions of hearts fail each year. Why can’t we replace them?

 

The Bivacor heart contains a single titanium chamber with a rotor that spins at its center, sending blood out to the body

 

Bivacor is in a transitional stage. It has never sold a product and is still run entirely on venture capital, angel investment, and government grants. Its hearts have been implanted in sheep and calves, which have survived for months, occasionally jogging on treadmills; it’s preparing to submit an application to the Food and Drug Administration for permission to perform human implantations.

 

To cross the animal-human threshold is to enter a harsh regulatory environment. In the early days of artificial-heart research, a team could implant a device in a dying person on an emergency basis—as a last-ditch effort to save his life—and see how it functioned.

 

Ethicists were uneasy, but progress was swift. Today, such experimentation is prohibited: a heart’s design must be locked in place and approved before a clinical trial can begin; the trial may take years, and, if it reveals that the heart isn’t good enough, the process must start again.

 

Bivacor is currently deciding which features will be included in the clinical trial of its heart. A wrong decision would likely sink the company; almost certainly, there wouldn’t be a second attempt on the summit.

 

read this fabulous article at https://www.newyorker.com/magazine/2021/03/08/how-to-build-an-artificial-heart?utm_source=pocket-newtab-intl-en

 

 

 

 

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From Scans, Doctors 3D Print Custom Heart Wraps to Deliver Treatments

From Scans, Doctors 3D Print Custom Heart Wraps to Deliver Treatments | healthcare technology | Scoop.it

The buzz about 3D printing can at times give the impression that the technology is a panacea that makes all manufacturing cheaper. The truth is 3D printing has one very specific use case: It makes prototypes and custom, one-of-a-kind items cheaper and faster to make.


Medicine would seem like a prime beneficiary of this technology, potentially using 3D printing to provide patients with custom-made implants and stents. Yet, to date, medical researchers have focused on the most ambitious goals for the technology, such as replacement organs printed from a patient’s own stem cells, which need years of development before they reach average patients.


Recently, a somewhat more modest medical device — and one that could find its way relatively quickly into treatment protocols — was created using 3D printing. Researchers Igor Efimov from Washington University in St. Louis and John Rogers from University of Illinois at Urbana-Champaign used MRI and CT scans of rabbit and human hearts to 3D-print custom-fitting flexible mesh sacs that fit each heart perfectly and stayed in place as it beat.


“Each heart is a different shape, and current devices are one-size-fits-all and don’t at all conform to the geometry of a patient’s heart,” said Efimov.


Inside its fabric, the mesh can also hold sensors that monitor for signs of trouble and deliver electrical pulses, if needed. The sensors are embedded in the fabric using technology similar to what Google has said it will use in sugar-monitoring contact lenses, only more nuanced.


Doctors can position the sensors or electrodes more precisely using the wrap than by attaching them directly to the heart with sutures or adhesives, Efimov and Rogers state in a recent paper in Nature Communications. They demonstrate in the paper that sensors attached to the mesh (or multifunctional integumentary membrane) accurately measure temperature, mechanical strain and pH, and could deliver pulses of electricity.


Depending on the sensors used, the heart wrap could improve treatments for a range of disorders; it could also be used to deliver medication directly to where its needed. But the device was conceptualized specifically to treat ventricle deformities and arrhythmias. The arrhythmia atrial fibrillation affects about 4 million Americans; patients often undergo a surgery that destroys the heart’s own drummer, the atrioventricular node, and subsequently receive a pacemaker.

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Smartphones to Check Cholesterol Levels - DIY cholesterol monitoring

Smartphones to Check Cholesterol Levels - DIY cholesterol monitoring | healthcare technology | Scoop.it

Home self-diagnostic tools for blood cholesterol monitoring have been around for over a decade but their widespread adoption has been limited by the relatively high cost of acquiring a quantitative test-strip reader, complicated procedure for operating the device, and inability to easily store and process results. 


Forget those clumsy, complicated, home cholesterol-testing devices.


David Erickson and co-workers from Cornell University in New York  have developed a simple system that enables people to routinely monitor their blood cholesterol levels, using a smartphone.


They have created the Smartphone Cholesterol Application for Rapid Diagnostics, or “smartCARD,” which employs your smartphone’s camera to read your cholesterol level.


With this, one can now take an accurate iPhone camera selfie that could save ones life – it reads ones cholesterol level in about a minute.


Their system consists of a small accessory device that attaches onto a smartphone, an app, and dry reagent test strips for measuring blood cholesterol levels that are already commercially available. A drop of blood is placed onto the test strip and an enzymatic, colorimetric reaction occurs. This strip is then placed into the accessory device and an image of the strip is generated using the camera on the phone. The app then quantifies the colour change and converts this into a blood cholesterol concentration using a calibration curve.


Erickson and co-workers are now working to commercialise their system, so it may be available for the general public to purchase in the near future.




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Why Apple, Google, Amazon hired cardiologists

Why Apple, Google, Amazon hired cardiologists | healthcare technology | Scoop.it
  • The world's largest technology companies have all hired well-known cardiologists.
  • Heart disease and high blood pressure affect a large number of people, are well-understood, and there's evidence that consumer products can help.

 

Big Silicon Valley companies have often competed for talent with specialized skills, like expertise in artificial intelligence or trendy new programming languages.

 

Now they're competing for heart doctors.

 

Apple, Alphabet, and Amazon have all hired well-known cardiologists.

 

This might just be a coincidence. Cardiologists tend to be well educated and hard working, and big tech companies have a track record of recruiting such people.

 

In recent years, all of these companies have started to invest in products and devices that are targeted to millions of people who could benefit by tracking their heart health.

 

Apple's smartwatch now includes an electrocardiogram, which can detect heart rhythm irregularities. Verily's study watch, which is designed for clinical trial research, also tracks heart rate and heart rhythm, and it's doing a lot of work in chronic disease management. 

 

So the more likely explanation is that tech companies are interested in health care, and they have all come to the conclusion that cardiology should be an early (if not initial) target.

 

Here's why.

 

 

It's a huge potential market

Heart disease is the No. 1 killer in the world, and strokes are among the leading causes of death.

 

And that's not all that cardiologists treat. "Our scope covers other common disease such as high blood pressure, which impacts about a third of people in the U.S. — 75 million Americans — as well as lipid and cholesterol disorders," said Dr. Mo Elshazly, a cardiologist and assistant professor of medicine at Weill Cornell Medicine.

 

Many cardiologists are also experts in nutrition and exercise science, which impacts a huge number of people who are committed to staying healthy.

 

That's useful for the teams within the largest tech companies that are more focused on wellness and fitness applications, rather than on health and medical.

 

Alphabet has Google Fit. Apple has a fitness group for its Apple Watch. And Amazon is looking at health and wellness applications for its Alexa voice assistant.

It's well-studied

Cardiology is among the most-studied fields in medicine, meaning there's already a lot of evidence to understand the root causes of heart disease, as well as how to prevent it. That's attractive for tech companies, which tend to base their development decisions on data.

Their consumer products are already making a difference

Let's take Apple, as an example. The company launched its first Apple Watch model with a heart rate sensor, never expecting that people would use it to discover they were pregnant, at risk for a heart attack or experiencing a dangerous irregular heart rhythm.

But as people began sharing examples of how the Apple Watch saved their life, the company started to invest heavily in the science and technology to drive more of these stories. A lot of that work culminated in the first-ever clearance for a heart rhythm sensor called an ECG for Apple Watch earlier in the summer.

 

 

read more at https://www.cnbc.com/2018/10/17/what-every-tech-company-needs-a-cardiologist.html

 

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Left Atrial Pressure Monitoring To Optimize Heart Failure (Trial)

Left Atrial Pressure Monitoring To Optimize Heart Failure (Trial) | healthcare technology | Scoop.it
LAPTOP-HF is designed to investigate a new way to help treat heart failure. Since many heart failure patients are frequently hospitalized and often feel poorly, the hope is that this system may help your doctor adjust your medications before you develop symptoms or require hospitalization.


This is accomplished by measuring pressure in the heart and then each day providing you with your physician’s updated recommended medications and dosages. These may change daily depending on your condition. This is very similar to how diabetics manage their glucose levels. -


See more at: http://www.kumed.com/heart-care/clinical-services/heart-care-clinical-trials/laptop-hf#sthash.EfEC2fvM.dpuf