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New tool activates deep brain neurons by combining ultrasound, genetics

New tool activates deep brain neurons by combining ultrasound, genetics | healthcare technology | Scoop.it

Neurological disorders such as Parkinson's disease and epilepsy have had some treatment success with deep brain stimulation, but those require surgical device implantation.

 

A multidisciplinary team at Washington University in St. Louis has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely control motor activity without surgical device implantation.

 

The team, led by Hong Chen, is the first to provide direct evidence showing noninvasive, cell-type-specific activation of neurons in the brain of mammal by combining ultrasound-induced heating effect and genetics, which they have named sonothermogenetics.

 

It is also the first work to show that the ultrasound- genetics combination can robustly control behavior by stimulating a specific target deep in the brain.

 

Results of the three years of research, which was funded in part by the National Institutes of Health's BRAIN Initiative, were published online in Brain Stimulation May 11, 2021.

 

"Our work provided evidence that sonothermogenetics evokes behavioral responses in freely moving mice while targeting a deep brain site," Chen said. "Sonothermogenetics has the potential to transform our approaches for neuroscience research and uncover new methods to understand and treat human brain disorders."

 

 

more at https://medicalxpress.com/news/2021-05-tool-deep-brain-neurons-combining.html

 

 

Nassima Chraibi's curator insight, January 9, 2023 12:07 PM
This article discusses a new non-invasive deep brain stimulation technique, called sonothermogenetics, which allows to precisely target certain types of neurons. This new technique could allow the development of new methods and research on brain disorders.
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Technoclinics- Upcoming scenario in India

Technoclinics- Upcoming scenario in India | healthcare technology | Scoop.it

Medical industry in India is proud to have adopted the latest medical equipments in every specialization and has achieved tremendous results in terms of rapid and effective treatment. The benefits that the Indian IT sector has made in the global village the past 15 years, are now being extended to the Indian Healthcare industry too!

 

Taking advantage of these some clinics are transforming into “technoclinics” by smartly using technology and software in their practice.

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AI algorithm that can detect the presence of COVID-19 disease in Chest X Rays

AI algorithm that can detect the presence of COVID-19 disease in Chest X Rays | healthcare technology | Scoop.it

“ATMAN AI”, an Artificial Intelligence algorithm that can detect the presence of COVID-19 disease in Chest X Rays, has been developed to combat COVID fatalities involving lung. ATMAN AI is used for chest X-ray screening as a triaging tool in Covid-19 diagnosis, a method for rapid identification and assessment of lung involvement. This is a joint effort of the DRDO Centre for Artificial Intelligence and Robotics (CAIR), 5C Network & HCG Academics. This will be utilized by online diagnostic startup 5C Network with support of HCG Academics across India.

 

Triaging COVID suspect patients using X Ray is fast, cost effective and efficient. It can be a very useful tool especially in smaller towns in India owing to lack of easy access to CT scans there.

 

This will also reduce the existing burden on radiologists and make CT machines which are being used for COVID be used for other diseases and illness owing to overload for CT scans.

 

The novel feature namely “Believable AI” along with existing ResNet models have improved the accuracy of the software and being a machine learning tool, the accuracy will improve continually.

 

Chest X-Rays of RT-PCR positive hospitalized patients in various stages of disease involvement were retrospectively analysed using Deep Learning & Convolutional Neural Network models by an indigenously developed deep learning application by CAIR-DRDO for COVID -19 screening using digital chest X-Rays. The algorithm showed an accuracy of 96.73%.

 

 read more at http://indiaai.gov.in/news/drdo-cair-5g-network-and-hcg-academics-develop-atman-ai

 

 

nrip's insight:

Utilizing algorithms for chest X-ray is an effective triaging tool. Once perfected these can accessible by people in remote areas. Thus offering significant improvements in the care process as encountered in rural and remote areas.

 

Similar methods are being used/experimented on by a variety of labs and digital health companies, for predominant respiratory diseases.

 

Plus91 has developed similar technology for different Pneumonia and TB.

 

nrip's curator insight, May 12, 2021 3:17 AM

Utilizing algorithms for chest X-ray is an effective triaging tool. Once perfected these can accessible by people in remote areas. Thus offering significant improvements in the care process as encountered in rural and remote areas.

 

Similar methods are being used/experimented on by a variety of labs and digital health companies, for predominant respiratory diseases.

 

Plus91 has developed similar technology for different Pneumonia and TB.

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EMR'S: PROVIDING INDIAN DOCTORS WITH AN EDGE: VOL 1

EMR'S: PROVIDING INDIAN DOCTORS WITH AN EDGE: VOL 1 | healthcare technology | Scoop.it

Typically, a patient's record is just a folder with his details and probably a photograph on the front cover, coupled with sheets and sheets of data recording his previous visits. While some of this data, especially prescriptions may be recorded in a hospital, can you imagine the long hard search that one endures to locate them when required. Also, this search by no means guarantees a consolidated view of a patient's information which would equip the doctor with a complete overview of the patient's health history

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