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CVD is no longer considered a disorder of lipid (fat) accumulation or elevated cholesterol, but rather a disease process characterized by low-grade inflammation of the vascular (artery) lining and an inappropriate wound healing of the blood vessels.
It is similar to a low-grade wound on your skin that does not heal, but it is on the inside. There is now extensive and rapidly growing evidence that inflammation, which is what you get with every wound, plays a critical role in all stages of CVD. That is why if you treat the cholesterol you are treating the symptoms, yet if you treat the inflammation you are treating the underlying cause of the disease...
Good pointer on cholesterol and heart disease...