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Belgian researchers from VIB-KU Leuven Center for Microbiology and VIB-UGent Center for Plant Systems Biology have developed a new toolbox of 16 different short DNA sequences that allow triggering controlled and specific recombination events in any genome. 
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Belgian researchers from the VIB-KU Leuven Center for Microbiology and the VIB-UGent Center for Plant Systems Biology have extended the toolbox that uses a viral recombinase (Cre) so that it can now specifically recognize, cut and paste multiple DNA sites. The team has identified a set of 16 sites that recombine efficiently with the same site, but not with any other site in that set, for different organisms. This new patented toolbox, complementary to CRISPR, and for some applications going beyond it, is now available to researchers and industrialists in the field of genome engineering. The results are reported today in two simultaneous articles in the prestigious journal Nature Communications.