Virology News
66.9K views | +0 today
Follow
Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
Curated by Ed Rybicki
Your new post is loading...
Your new post is loading...
Scooped by Ed Rybicki
Scoop.it!

Recombination hotspots and host susceptibility modulate the adaptive value of recombination during maize streak virus evolution

Recombination hotspots and host susceptibility modulate the adaptive value of recombination during maize streak virus evolution | Virology News | Scoop.it
Maize streak virus -strain A (MSV-A; Genus Mastrevirus, Family Geminiviridae), the maize-adapted strain of MSV that causes maize streak disease throughout sub-Saharan Africa, probably arose between 100 and 200 years ago via homologous recombination...

 

Sometimes you have to be proud of your academic children...B-)

 

Picture courtesy Russell Kightley Media

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

HPV Might Put Women’s Hearts at Risk | HPV Treatment Association

HPV Might Put Women’s Hearts at Risk | HPV Treatment Association | Virology News | Scoop.it

A virus responsible for [the majority of] cervical cancer[s] might also raise a woman's risk of heart attack and stroke, according to researchers who suggest HPV might underlie some cardiovascular diseasein people who do not have such traditional risk factors as obesity, diabetes or smoking.

 

Interesting!  Even more reason to vaccinate young people

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Vietnam may begin producing H5N1 vaccines for humans next year | The Jakarta Post

Vietnam may begin producing H5N1 vaccines for humans next year | The Jakarta Post | Virology News | Scoop.it
Nguyen Tran Hien: www.ianphi.orgVietnam may begin producing bird flu vaccines for humans next year, according to the National Institute of Hygiene ...

 

Developing countries: doing it for themselves.  Because no-one else will.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

MicrobiologyBytes » Blog Archive » First RNA virus-encoded miRNAs

MicrobiologyBytes » Blog Archive » First RNA virus-encoded miRNAs | Virology News | Scoop.it
Well, not really an RNA virus, given that it has a DNA stage to the lifecycle - but possibly the smallest virus genome known to make miRNAs?

Thanks AJC!
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Human Testing Of New HIV-Vaccine

Human Testing Of New HIV-Vaccine | Virology News | Scoop.it
Scientists from the Antwerp Institute of Tropical Medicine, Antwerp University Hospital and Antwerp University have tested a new 'therapeutic vaccine' against HIV on volunteers.

 

The next wave of HIV vaccines: we have so many HIV-infected people alive because of ARVs, that other interventions are starting to be seriously trialled.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Weighing Baby Vaccine Risks: Potential Dangers of Vaccines | Inhabitots - StumbleUpon

A pretty reasonable overview of the pros and cons of vaccinating children - which manages to be mostly pro.

 

As it should be.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Book Review: Virolution

Carl Zimmer reviews Frank Ryan's Virolution: The Most Important Evolutionary Book Since Dawkins' Selfish Gene.

 

"We are part virus. This bizarre yet inescapable fact has been revealed over the past 30 years, as scientists have spelunked their way through the human genome and encountered stretches of DNA with the telltale chemical signatures of viruses."

 

I thoroughly enjoyed this one.

No comment yet.
Suggested by Kerry Gordon
Scoop.it!

Mammals Made By Viruses | The Loom | Discover Magazine

Mammals Made By Viruses | The Loom | Discover Magazine | Virology News | Scoop.it
A Planet of Viruses | If not for a virus, none of us would ever be born.In 2000, a team of Boston scientists discovered a peculiar gene in the human genome.

 

Thanks Kerry!

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

India, US aim to develop single-shot vaccine for Foot & Mouth Disease by 2030 - The Times of India

India, US aim to develop single-shot vaccine for Foot & Mouth Disease by 2030 - The Times of India | Virology News | Scoop.it
In its effort to eradicate the deadly Foot & Mouth Disease (FMD) in animals by 2030, India has joined hands with the US to jointly develop a new-age single-shot vaccine.

 

...the new recombinant clone adenovirus virus base vaccine will be sturdier, require less cold storage and be more effective than the present vaccine.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Decision time for researchers of deadly bird flu | Reuters

LONDON/GENEVA (Reuters) - When 22 bird flu experts meet at the World Health Organisation (WHO) this week, they will be tasked with deciding just how far scientists should go in creating lethal mutant viruses (Decision time for researchers of deadly...
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Almost 800 adverse reactions to swine flu vaccine identified - The Irish Times - Mon, Feb 13, 2012

Almost 800 adverse reactions to swine flu vaccine identified - The Irish Times - Mon, Feb 13, 2012 | Virology News | Scoop.it
THE SWINE flu vaccine has topped the list of drugs responsible for the largest number of suspected adverse reactions, new figures show.

 

...followed by (in third place) the HPV vaccine, then other childhood vaccines.  But "Most of these were relatively mild, such as localised swelling, gastrointestinal problems and flu-like symptoms."

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Some African Sex Workers Are Naturally HIV Resistant

Some African Sex Workers Are Naturally HIV Resistant | Virology News | Scoop.it
HIV-resistant sex workers in Africa have a weak inflammatory response in their vaginas – a surprise for researchers, who were expecting the contrary considering the women’s high exposure to the virus.
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Baculovirus GP64-Mediated Entry into Mammalian Cells

Baculovirus GP64-Mediated Entry into Mammalian Cells | Virology News | Scoop.it

"These results suggest that cholesterol in the plasma membrane, dynamin- and clathrin-dependent endocytosis, and macropinocytosis play crucial roles in the entry of viruses bearing baculovirus GP64 into mammalian cells."

 

And VLPs: see next one....

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Who DID show that influenza was a virus?

Who DID show that influenza was a virus? | Virology News | Scoop.it

The history books will tell you that it was only in 1933 that Influenza A virus was shown to BE a virus - yet there appears to me to be very clear evidence that French scientists working in 1918 actually made the first call.  From "Quelques notions experimentales sur le virus de la grippe", by MM Charles Nicolle and Charles Lebailly in Annales de l'Institut Pasteur of 1918:

 

Conclusions

1⁰ The bronchial expectoration of people suffering from influenza, collected during the acute period, is virulent.
2⁰ The monkey (M. cynomolgus) is sensitive to the virus by sub-conjunctival and nasal inoculation.
3⁰ The influenza agent is a filterable organism. The inoculation of the filtrate has indeed reproduced the illness in two of the people injected subcutaneously; on the other hand when given intravenously it appears to be ineffective (two failures out of two tries).
4⁰ It is possible that the flu virus does not occur in the patient’s blood. The blood of a monkey with flu, inoculated subcutaneously, did not infect man; the negative blood result of subject 2 at D, is however, not convincing, the blood route seeming to be ineffective for the flu virus transmission.

(Translated by Mrs Francoise Williamson)

 

It convinced me.  But, as my medical colleagues will be quick to tell you, I'm an amateur in this area.  Albeit an enthusiastic one...B-)

 

Picture courtesy of Russell Kightley Media

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Amazon.com: The Great Influenza: The Epic Story of the Deadliest Plague In History: John M. Barry: Books

Amazon.com: The Great Influenza: The Epic Story of the Deadliest Plague In History: John M. Barry

 

Greatest outbreak, maybe, but smallpox killed 300 million laste century alone?  Ah, well - still a good story!

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Video: Intranasal Norovirus VLP vaccine demonstrating clinical efficacy in Phase I/II Trial - Vaccine Nation - Strategy and innovation in vaccines

Video: Intranasal Norovirus VLP vaccine demonstrating clinical efficacy in Phase I/II Trial - Vaccine Nation - Strategy and innovation in vaccines | Virology News | Scoop.it
The presentation covered:
Phase I/II randomized, double blind, multi-center, placebo-controlled safety and efficacy study designed to evaluate the norovirus monovalent GI.1 VLP vaccine versus placebo

Results from the Norovirus vaccine proof-of-concept, multi-center challenge study

Ongoing clinical study of an intramuscular bivalent formulation of norovirus vaccine candidate

 

Of course, they don't mention you can make it in plants too....

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Bird flu news / bird flu in poultry - Latest news and information on bird flu, avian influenza

Catch up with the latest bird flu news from across the globe with our daily bird flu updates...

 

Great site to follow avian flu

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

PLoS ONE: Modelling the Wind-Borne Spread of Highly Pathogenic Avian Influenza Virus between Farms

PLoS ONE: Modelling the Wind-Borne Spread of Highly Pathogenic Avian Influenza Virus between Farms | Virology News | Scoop.it

A quantitative understanding of the spread of contaminated farm dust between locations is a prerequisite for obtaining much-needed insight into one of the possible mechanisms of disease spread between farms. Here, we develop a model to calculate the quantity of contaminated farm-dust particles deposited at various locations downwind of a source farm and apply the model to assess the possible contribution of the wind-borne route to the transmission of Highly Pathogenic Avian Influenza virus (HPAI) during the 2003 epidemic in the Netherlands.

 

Atmospherics and physics meets viruses....

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

More must be done to prevent hepatitis C transmission amongst HIV positive gay men - - - Press Releases - News & Media - National AIDS Trust - NAT

NAT has launched a report, ‘HIV and Hepatitis C Co-infection’, which looks at hepatitis C co-infection among HIV positive men gay men and the UK’s response to this growing health challenge...

 

Treat one, and another pops up.  Roll on the HCV vaccine!

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

More Doctors 'Fire' Vaccine Refusers

More Doctors 'Fire' Vaccine Refusers | Virology News | Scoop.it
Pediatricians fed up with parents who refuse to vaccinate their children out of concern it can cause autism or other problems increasingly are firing such families from their practices, raising questions about a doctor's responsibility to these...

 

Unethical, possibly, but stupid people are their own worst enemies.  Trouble is, they extend it to their children.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Nature News Special : Mutant flu

Nature News Special : Mutant flu | Virology News | Scoop.it

Scientists have created a form of the H5N1 avian flu virus that is transmissible between mammals, raising fears that it could trigger a human pandemic if it escapes from the lab - either through accidental release or as part of a bioterror attack. As debate rages over how much of the research should be published, and whether there is sufficient oversight of such work, you can follow all Nature's coverage of the issue here.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

PLoS ONE: Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis

PLoS ONE: Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis | Virology News | Scoop.it

Using the self-controlled case series design we examined 271,495 12 month vaccinations and 184,312 18 month vaccinations to examine the relative incidence of the composite endpoint of emergency room visits or hospital admissions in consecutive one day intervals following vaccination....

 

There are significantly elevated risks of primarily emergency room visits approximately one to two weeks following 12 and 18 month vaccination.

 

HOWEVER [Ed]:

Given the effectiveness of the MMR vaccine in eliminating both measles and rubella, and the highly infectious nature of these diseases, high vaccination coverage is essential. The diseases that the vaccines are preventing are not benign and vaccination can eliminate many of the serious sequelae of these infections [20]. Complications from measles include otitis media (7–9% of cases), pneumonia (1–6% of cases), encephalitis (1 per 1,000–2,000 cases), subacute sclerosing panecephalitis (1 per 100,000 cases), and death (1 per 3000 cases) [3], [21]. Further studies attempting to predict which children develop post-vaccination reactions, as well as determining the effectiveness of prophylactic treatment with antipyrectics prior to the high risk period for symptom development are warranted.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Small Things Considered: It’s Raining Viruses!

Small Things Considered: It’s Raining Viruses! | Virology News | Scoop.it
by Merry Youle

It’s true! Each year it rains viruses, more than a trillion of them per acre over thousands of forested acres in the USA.

 

Imagine that: they'll be spraying live bacteria next...oh, wait!  They do!!

No comment yet.
Suggested by Chris Upton + helpers
Scoop.it!

Death-rate row blurs mutant flu debate : Nature News & Comment

Death-rate row blurs mutant flu debate : Nature News & Comment | Virology News | Scoop.it
Even if a 59% mortality rate for H5N1 is too high, the virus could still cause a flu pandemic more serious than that of 1918.
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Virology Journal | Full text | Abrogation of contaminating RNA activity in HIV-1 Gag VLPs

"HIV-1 Gag virus like particles (VLPs) used as candidate vaccines are regarded as inert particles as they contain no replicative nucleic acid, although they do encapsidate cellular RNAs."

 

In light of HPV VLPs being flagged as containing HPV DNA, this is interesting as it gives an idea of how to get rid of the NA in the HIV Pr55Gag particles.  Plus, my lab wrote it.

No comment yet.