Virology News
66.9K views | +0 today
Follow
Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
Curated by Ed Rybicki
Your new post is loading...
Your new post is loading...
Scooped by Ed Rybicki
Scoop.it!

Has vaccine reaction made cat lethargic? - STLtoday.com

Has vaccine reaction made cat lethargic?STLtoday.comI took her to the vet, had her checked out, vaccinated, etc. At the time, the vet estimated that she was about 2. The other day, I took her in for her yearly rabies shot.

 

Do some people really have nothing better to worry about?  How about: yes, there may be some reaction to the vaccine - BUT YOUR FRIKKIN' CAT WON'T GET RABIES!!!

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

General Assembly, CDC Diverge on HPV Vaccine

General Assembly, CDC Diverge on HPV Vaccine | Virology News | Scoop.it
While Virginia is moving to repeal the requirement that girls get vaccinated against the human papillomavirus, the federal government and a major medical association are urging just the opposite: that boys as well as girls receive the vaccine...

 

There ought to be an IQ test to participate in civil society...

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Virology Journal | Lassa virus-like particles displaying all major immunological determinants as a vaccine candidate for Lassa hemorrhagic fever

Lassa fever is a neglected tropical disease with significant impact on the health care system, society, and economy of Western and Central African nations where it is endemic.

 

An older article, but...

"LASV VLP can be generated displaying high levels of immunogenic viral proteins, and that small laboratory scale mammalian expression systems are capable of producing multi-milligram quantities of pseudoparticles. These VLP are structurally and morphologically similar to native LASV virions, but lack replicative functions, and thus can be safely generated in low biosafety level settings. LASV VLP were immunogenic in mice in the absence of adjuvants, with mature IgG responses developing within a few weeks after the first immunization. These studies highlight the relevance of a VLP platform for designing an optimal vaccine candidate against Lassa hemorrhagic fever, and warrant further investigation in lethal challenge animal models to establish their protective potential.

 

People need to start paying attention to this virus...and another candidate for Green Technology.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Virology Journal | Genetic relationships and epidemiological links between wild type 1 poliovirus isolates in Pakistan and Afghanistan

Efforts have been made to eliminate wild poliovirus transmission since 1988 when the World Health Organization began its global eradication campaign. Since then, the incidence of polio has decreased significantly. However, serotype 1 and serotype 3 still circulate endemically in Pakistan and Afghanistan. Both countries constitute a single epidemiologic block representing one of the three remaining major global reservoirs of poliovirus transmission. In this study we used genetic sequence data to investigate transmission links among viruses from diverse locations during 2005-2007.

 

The last places on the planet where wild-type polio is circulating: the focus will definitely become more obsessive

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

The Malian HIV Warrior Presidents Can't Say No To - AllAfrica.com

The Malian HIV Warrior Presidents Can't Say No To - AllAfrica.com | Virology News | Scoop.it
The Malian HIV Warrior Presidents Can't Say No ToAllAfrica.com

He pressed China to admit that HIV was spreading rapidly among gay men and drug users and that the 500000 Chinese working in Africa and 40 million migrant labourers, many of whom visit...

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Amazon.com: Phage Display In Biotechnology and Drug Discovery eBook: Sachdev S. Sidhu: Kindle Store

Amazon.com: Phage Display In Biotechnology and Drug Discovery eBook: Sachdev S.

"The first and only guide to showcase the impact of phage display technology on drug discovery, this reference details the theories, principles, and methods impacting the field and demonstrates applications for peptide phage display, protein phage display, and the development of novel antibodies. Highlighting the current and future role of phage display in the development of protein therapeutics, this book provides a comprehensive overview that will prove invaluable to anyone researching recombinant antibodies."

 

Phages and biotechnology: what's not to like?  The price, possibly??

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Sexually transmitted diseases caused by viruses - by PRS - Helium

There are four  sexually transmitted diseases (STDs) that are caused by viruses.  They are Human Immunodeficiency Virus (HIV), Human Papillomavirus (HPV), Herpes Simplex Virus (HSV), and Hepatitis C.

 

Useful refresher, in case you thought it was time to get back on the circuit.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Editor's concern over bird flu

Editor's concern over bird flu | Virology News | Scoop.it
The editor of a leading scientific journal says he will publish full details of controversial research into the bird flu virus, unless the World Health Organization gives scientists crucial information.

 

Go Bruce...!!

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Vaccines for HIV: A new design strategy

Vaccines for HIV: A new design strategy | Virology News | Scoop.it
HIV has eluded vaccine-makers for thirty years, in part due to the virus' extreme ability to mutate.

 

With a mathematical tool called random matrix theory, the team searched for high-order evolutionary constraints in the so-called Gag region of HIV. The researchers were looking for collectively co-evolving groups of amino acids with a high number of negative correlations (meaning multiple mutations would destroy the virus) and a low number of positive correlations (meaning the virus could survive multiple mutations). They found this combination in a region, which they call Gag sector 3, that is involved in stabilizing the protein shell of the virus: too many mutations here, and the virus' structure would collapse.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Flu vaccine helps prevent too-small babies

Flu vaccine helps prevent too-small babies | Virology News | Scoop.it
Vaccinating pregnant women against the flu protects their babies from being born too small, new research suggests.

 

And, in the case of H1N1(2009) flu, may stop the mothers dying.  Yet more reasons to vaccinate everyone!

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Virology Journal | Abstract | Rabies molecular virology, diagnosis, prevention and treatment

Virology Journal | Abstract | Rabies molecular virology, diagnosis, prevention and treatment | Virology News | Scoop.it
Rabies is an avertable viral disease caused by the rabid animal to the warm blooded animals (zoonotic) especially human. Rabies occurs in more than 150 countries and territories.

 

A very useful review on something that is an underestimated problem in developing countries.

Image courtesy of Russell Kightley Media (http://www.rkm.com.au)

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Virology Journal | Rapid detection of sacbrood virus (SBV) by one-step reverse transcription loop-mediated isothermal amplification assay

Sacbrood virus (SBV) primarily infects honeybee broods, and in order to deal with the problem cost effective detection methods are required.

 

...and LAMP (http://en.wikipedia.org/wiki/Loop-mediated_isothermal_amplification) turns out to be a good way to do it!  Like this...

http://nar.oxfordjournals.org/content/28/12/e63/F1.large.jpg

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Hepatitis C-related deaths outpace HIV deaths, study says | From …

Hepatitis C-related deaths outpace HIV deaths, study says | From … | Virology News | Scoop.it
Hepatitis C-related deaths outpace HIV deaths, study says | From … http://t.co/iP0ktxnz...

 

...but not in Africa or Asia, I'd be willing to bet.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Amazon.com: The Virus and the Vaccine: The True Story of a Cancer-Causing Monkey Virus, Contaminated Polio Vaccine, and the Millions of Americans Exposed (9780312278724): Debbie Bookchin, Jim Schum...

Amazon.com: The Virus and the Vaccine: The True Story of a Cancer-Causing Monkey Virus, Contaminated Polio Vaccine, and the Millions of Americans Exposed (9780312278724): Debbie Bookchin, Jim Schumacher: Books (The Virus and the Vaccine: The True ...

 

Sad thing is, it really is true - I've used it as a cautionary tale to my students for nigh on 30 years

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Mystery virus kills thousands of lambs - Telegraph

Mystery virus kills thousands of lambs - Telegraph | Virology News | Scoop.it
Thousands of lambs have been killed by a new virus that is threatening the
survival of many British farms.

 

Schmallenberg bites deep.  Be interesting to see where it came from originally!

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Virology Journal | Abstract | Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

Virology Journal | Abstract | Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity | Virology News | Scoop.it
VLPs were subjected to post-purification disassembly and reassembly (D/R) treatment during bioprocessing to improve VLP immunoreactivity and stability. The post-D/R HPV16 VLPs and their complex with H16.V5 neutralizing antibody Fab fragments were visualized by cryo electron microscopy, showing VLPs densely decorated with antibody. Along with structural improvements, post-D/R VLPs showed markedly higher antigenicity to conformational and neutralizing monoclonal antibodies (mAbs) H16.V5, H16.E70 and H263.A2, whereas binding to mAbs recognizing linear epitopes (H16.J4, H16.O7, and H16.H5) was greatly reduced. Strikingly, post-D/R VLPs showed no detectable binding to H16.H5, indicating that the H16.H5 epitope is not accessible in fully assembled VLPs. An atomic homology model of the entire HPV16 VLP was generated based on previously determined high-resolution structures of bovine papillomavirus and HPV16 L1 pentameric capsomeres.

 

Image courtesy of Russell Kightley Media

 

 

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Bacteriophage T4 and Its Relatives. A Series of Critical Reviews: Amazon.co.uk: Jim D Karam, Eric S Miller: Books

Bacteriophage T4 and Its Relatives.A Series of Critical Reviews: Amazon.co.uk: Jim D Karam, Eric S Miller: Books...

 

Gotta love T4: it's EVERYWHERE...and the coolest piece of nanotechnology on the planet

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

H5N1: Vietnam: Human trials for H5N1 vaccine successful

Via VietNam News: Human trials for birdflu vaccine successful.

Viet Nam has successfully produced experimental version of bird flu vaccine to combat the virus which has killed 62 people in 9 years, researchers at Vaccine and Biological Production Company No.1, said.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

New Vaccination Guidelines: HepB for Diabetics; HPV for Young Men

New Vaccination Guidelines: HepB for Diabetics; HPV for Young Men | Virology News | Scoop.it
There were a number of changes to the 2012 clinical guidelines that doctors follow for adult immunizations, released by a federal panel.

 

Yet another recommendation that young men get HPV vaccinations: time to start listening, boys!

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Enhanced pneumonia and disease in pigs vaccinated wi... [Vaccine. 2011] - PubMed - NCBI

"...these results suggest that inactivated SIV vaccines may potentiate clinical signs, inflammation and pneumonia following challenge with divergent homosubtypic viruses that do not share cross-reacting HI or SN antibodies."

 

Or: getting vaccinated with the wrong strain may hurt you during an epi/pandemic.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

H5N1 bird flu infection may be more common, less deadly, than thought

H5N1 bird flu infection may be more common, less deadly, than thought | Virology News | Scoop.it
The World Health Organization says the H5N1 bird flu kills nearly 60% of people who become infected, but a study released Thursday suggests the true fatality rate may actually be much lower.

 

...meaning a lot more people have been infected.  Possibly meaning the next pandemic is closer than we thought.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

CDC Warns That New Swine Flu Strain Has 'Pandemic Potential' - US News and World Report

The CDC says the strain has infected at least 18 Americans since 2010.

 

SO while you were all fussing about H5N1....

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

GlaxoSmithKline steps in to fund flu vaccine program

GlaxoSmithKline steps in to fund flu vaccine program | Virology News | Scoop.it
A pharmaceutical giant is picking up the federal government's slack in funding a program aimed at curbing flu infections.

 

...and will inevitably own it....

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

A Promising Trial HIV vaccine in Canada

A Promising Trial HIV vaccine in Canada | Virology News | Scoop.it
While an estimated 30 HIV vaccines are being tested around the world, one trial in Canada promises to be unique. After decades of research, development, and high hopes, scientists at the University of Western Ontario are ready to test a new type of vaccine known as SAV001 that they hope will prevent HIV infections.

What makes this trial different, said lead researcher Chil-Yong Kang, Ph.D., is that this is the first preventive vaccine to use a “killed whole” HIV-1 virus to activate a person’s immune system. This version of the virus, however, would be genetically altered so it would not be able to cause HIV infection. For insurance, the virus is also inactivated by using chemicals and radiation.

No comment yet.
Scooped by Ed Rybicki
Scoop.it!

The Scientist Who Discovered Hepatitis C Says He's Now Discovered the Vaccine

The Scientist Who Discovered Hepatitis C Says He's Now Discovered the Vaccine | Virology News | Scoop.it
In a poetic turn of virology, the scientist who discovered hepatitis C in 1989 has now also discovered a vaccine that will hopefully treat and prevent the disease.

 

Just shows you: stick with a thing for 20+ years....

No comment yet.