COVID-19-related non-pharmaceutical interventions impacted the circulation of other pathogens. Here, the authors compile a global viral activity dataset and compare the timing of resurgence of seven common respiratory viruses following the relaxation of interventions across different geographical...
When speaking of motors, most people think of those powering vehicles and human machinery. However, biological motors have existed for millions of years in microorganisms. Among these, many bacterial species have tail-like structures—called flagella—that spin around to propel themselves in fluids. These movements employ protein complexes known as the "flagellar motor."
University of Queensland researchers have for the first time introduced genetic material into plants via their roots, opening a potential pathway for rapid crop improvement. The research is published in Nature Plants.
The COVID-19 pandemic has underscored the urgent need for effective antiviral treatments, particularly as SARS-CoV-2 continues to evolve.Researchers are now focusing…...
Gene II Protein (Gp2/P2) is a nicking enzyme of the M13 bacteriophage that plays a role in the DNA replication of the viral genome. P2 recognizes a specific sequence at the f1 replication origin and nicks one of the strands and starts replication.
Ed Rybicki's insight:
Turns out that either M13 Rep recognises geminivirus Ori sequences, or the geminivirus Rep recognises M13 - because a geminivirus genomes cloned into M13 can be liberated as a replicon in E coli!
As experts continue monitoring and surveying the environment and the nation's food supply for H5N1 bird flu, a rash of dead cats has many officials on edge.
Over half of our genomes consist of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the genome, researchers at Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have now revealed their crucial role in early embryo development. The study is published in the journal Cell.
Kawasaki disease is an acute paediatric vasculitis of unknown origin. Environmental exposures have been suggested to contribute to disease development, but these remain to be defined.WHAT THIS STUDY ADDSThe findings suggest that infections are closely linked with Kawasaki disease, with a wider temporal association than previously described.Further, the data imply that many different agents may induce Kawasaki disease.
Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus's ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.
During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, the development of efficient serological tests for monitoring the dynamics of the disease as well as the immune response after illness or vaccination was critical.
Long COVID represents a significant challenge in understanding the prolonged impact of the disease. Despite its increasing recognition, detailed insights into the long-term cardiopulmonary consequences remain sparse.
Researchers review the ever-growing list of human viruses, examining their diversity, transmission pathways, and the urgent need for prevention and global surveillance.
The Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures has added the syphilis pathogen to its collection and makes it available to researchers around the world for scientific studies.
The incidence of male reproductive cancers, including prostate, testicular, and penile cancers, has risen in recent years, raising important health concerns. Prostate cancer is the second leading cause of cancer-related mortality in men, while penile cancer, though rare, typically affects men over...
Becoming Led Zeppelin explores the origins of this iconic group and their meteoric rise in just one year against all the odds.
Powered by awe-inspiring, psychedelic, never-before-seen footage, performances, and music, Bernard MacMahon’s experiential cinematic odyssey explores Led Zeppelin’s creative, musical, and personal origin story. The film is told in Led Zeppelin’s own words and is the first officially sanctioned film on the group.
Background: The Influenza A virus (IAV), a pathogen affecting the respiratory system, represents a major risk to public health worldwide. Immunization remains the foremost strategy to control the transmission of IAV.
Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999.
Science has revealed some of the secrets of the X chromosome, but many remain. In humans, female cells contain two X chromosomes (XX) and male cells contain one (XY). In each female cell, one X chromosome must be inactivated—crumpled up in such a way that the genetic code it contains cannot be read out.
Studies conducted in mice have shown that the COVID-19 vaccine being developed by researchers at the University of São Paulo's Medical School (FM-USP) in Brazil is safe and efficacious.
Genetically speaking, it's a bacterium's worst-case scenario: During transcription, newly minted RNA sticks to its DNA template, forming a 3-stranded structure known as an R-loop. While these structures have some important roles to play in a cell, R-loops in the wrong place at the wrong time can be disastrous, leading to DNA breaks, mutations, and cell death.
A deadly bird flu outbreak has wreaked havoc on U.S. chicken farms, claiming the lives of over 20 million egg-laying chickens last quarter, marking the worst impact on America's egg supply since the outbreak began in 2022.
DNA sequencing was revolutionized after scientists discovered a new bacterium in the hot springs of Yellowstone National Park, and today it's a common research technique.
The mosquito-borne Zika virus is known for causing microcephaly, a birth defect in which abnormal brain development results in a smaller-than-expected head.
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