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Intranasal immunization with synthetic recombinant vaccine containing multiple epitopes of influenza virus

The oligonucleotides coding for three epitopes (HA91-108, NP55-69, and NP 147-158) of influenza virus, stimulating B-cells, T-helper cells and cytotoxic T lymphocytes (CTLs), respectively, were previously employed for expressing each epitope in flagella that induced specific humoral and cellular ...
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
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Cann's Principles of Molecular Virology - 7th Edition

Cann's Principles of Molecular Virology - 7th Edition | Virology News | Scoop.it

Cann's Principles of Molecular Virology, - 7th Edition, revised by EP Rybicki. Print Book. ISBN 9780128227848. Now published!!


Instructor review copies: click on this link.

https://protect-za.mimecast.com/s/qU2qCNxKq0i0ZNRQxcmeDdo

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What causes rare heart inflammation after COVID vax?

What causes rare heart inflammation after COVID vax? | Virology News | Scoop.it
Researchers have identified the immune signature of rare cases of heart inflammation among those vaccinated against COVID with mRNA vaccines.
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Serologic response to porcine circovirus type 1 (PCV1) in infants vaccinated with the human rotavirus vaccine, Rotarix™: A retrospective laboratory analysis

In 2010, porcine circovirus type 1 (PCV1) material was unexpectedly detected in the oral live-attenuated human rotavirus (RV) vaccine, Rotarix™ (GSK Vaccines, Belgium). An initial study (NCT01511133) found no immunologic response against PCV1 in 40 vaccinated infants.
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Immune cells—not antibodies—cause COVID vaccine-linked myocarditis

Immune cells—not antibodies—cause COVID vaccine-linked myocarditis | Virology News | Scoop.it
The rare cases of myocarditis among recipients of mRNA vaccines are caused by a generalized immune-cell and inflammatory response, researchers say.
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“Faces are like water in my head”: What happens when COVID-19 affects the brain?

“Faces are like water in my head”: What happens when COVID-19 affects the brain? | Virology News | Scoop.it
Scientists are increasingly recognising that COVID-19 can have lasting and debilitating neurological symptoms, as well as causing structural changes to the brain.
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Differentiated cells may become precursor cells again

Differentiated cells may become precursor cells again | Virology News | Scoop.it
A loop in mitochondria—organelles within cells that produce energy for the body—may allow cells to retreat up the path of differentiation.
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SARS-CoV-2 Infection and Viral Fusogens Cause Neuronal and Glial Fusion that Compromises Neuronal Activity

SARS-CoV-2 Infection and Viral Fusogens Cause Neuronal and Glial Fusion that Compromises Neuronal Activity | Virology News | Scoop.it
Study: SARS-CoV-2 Infection and Viral Fusogens Cause Neuronal and Glial Fusion that Compromises Neuronal Activity (https://afludiary.blogspot.com/2023/06/study-sars-cov-2-infection-and-viral.html) (https://qbi.uq.edu.au/article/2023/06/covid-19-can-cause-brain-cells-%E2%80%98fuse%E2%80%99) Image ...
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Sowerby's Beaked Whale Gets Stranded on Beach, Dies in Suspected Bird Flu Case

Sowerby's Beaked Whale Gets Stranded on Beach, Dies in Suspected Bird Flu Case | Virology News | Scoop.it
Sowerby's beaked whales tend to spend their time on the North Atlantic's continental shelf, making it rare for them to make appearances or get stranded in shallow waters. Read to learn more.
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World must prepare for next “inevitable” pandemic, flu expert warns | The BMJ

World must prepare for next “inevitable” pandemic, flu expert warns | The BMJ | Virology News | Scoop.it

Elisabeth MahaseThe BMJConcerns over avian influenza viruses this year show that “we can’t drop our guard” and must prepare for the next “inevitable” pandemic, Nicola Lewis, director of the Worldwide Influenza Centre at the Francis Crick Institute, has warned.In an interview with The BMJ,1 Lewis said that “the threat of influenza hasn’t gone away, and it didn’t go away even when we had the covid-19 pandemic.” 

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How Covid made it nearly impossible to pass new vaccine rules

How Covid made it nearly impossible to pass new vaccine rules | Virology News | Scoop.it
Around the country, vaccine policy is on hold while lawmakers recover from a pandemic-policy hangover.
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Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus

Highly pathogenic avian influenza viruses from H5 clade 2.3.4.4b are circulating at unprecedently high levels in wild and domestic birds and have the potential to adapt to humans. We generated an mRNA lipid nanoparticle (LNP) vaccine encoding the hemagglutinin (HA) glycoprotein from a clade 2.3.4.4b H5 isolate. We show that the vaccine is immunogenic in mice and ferrets and prevents morbidity and mortality of ferrets following 2.3.4.4b H5N1 challenge.

Ed Rybicki's insight:
Of course, you don't need to do this - just make a DNA vaccine!! We did...https://journals.co.za/doi/abs/10.10520/EJC142058
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Science and Tech Innovation Drive Promise of Therapeutic Cancer Vaccines

Science and Tech Innovation Drive Promise of Therapeutic Cancer Vaccines | Virology News | Scoop.it
Science and Tech Innovation Drive Promise of Therapeutic Cancer Vaccines...
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Targeting the hallmarks of aging to improve influenza vaccine responses in older adults

Targeting the hallmarks of aging to improve influenza vaccine responses in older adults | Virology News | Scoop.it
Age-related declines in immune response pose a challenge in combating diseases later in life. Influenza (flu) infection remains a significant burden on older populations and often results in catastrophic disability in those who survive infection.
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How We Know Flu Really Did Disappear in 2020 and 2021 –

How We Know Flu Really Did Disappear in 2020 and 2021 – | Virology News | Scoop.it
Flu largely disappeared during 2020 and 2021, giving rise to ideas among some sceptics that it was being missed and wrongly classified as Covid. However, influenza surveillance data confirm that it really did vanish.
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Background - Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Background - Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | Virology News | Scoop.it
As background for the remainder of the report, this chapter presents a brief history of ME/CFS, a discussion of the terminology used for this illness, and a summary of the burden it imposes in the United States.
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Is the Spike in PCV2 Cases in Sows a Concern?

Is the Spike in PCV2 Cases in Sows a Concern? | Virology News | Scoop.it
The latest Swine Disease Reporting System report has some people scratching their heads. For the first time in recent memory, porcine circovirus type 2 jumped into the top 10 most-diagnosed diseases list at the ISU VDL.
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FDA advisers back RSV vaccine for pregnant women that protects their newborns

FDA advisers back RSV vaccine for pregnant women that protects their newborns | Virology News | Scoop.it
Federal health advisers are backing a first-of-its-kind RSV vaccine to protect newborns by immunizing their moms late in pregnancy. The virus fills hospitals with wheezing babies each winter. Pfizer's research shows a late-pregnancy shot is 82% effective at preventing severe RSV in the infants'...
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A self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults

A self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults | Virology News | Scoop.it
Palmer et al. present interim findings from their clinical trial; they describe the reactogenicity and immunogenicity results of a self-amplifying mRNA SARS-CoV-2 booster vaccine within an older population (≥60 years of age).
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Once 'defanged,' H5N1 bird flu is gaining teeth again

Once 'defanged,' H5N1 bird flu is gaining teeth again | Virology News | Scoop.it
The highly pathogenic bird flu that has been spreading around the world since 2020, devastating wild and domestic birds, and sometimes even sparking outbreaks in mammals, could eventually adapt to spread easily among humans.
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Charity demands urgent response plan to protect wild birds from avian influenza

Charity demands urgent response plan to protect wild birds from avian influenza | Virology News | Scoop.it
There has been a call for urgent action to protect wild birds in Northern Ireland from avian influenza.
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This Cow and Pig Influenza Virus Could Infect Humans: What We Know So Far

This Cow and Pig Influenza Virus Could Infect Humans: What We Know So Far | Virology News | Scoop.it
Scientific American is the essential guide to the most awe-inspiring advances in science and technology, explaining how they change our understanding of the world and shape our lives.
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Therapy for dog eye disease may benefit humans

Therapy for dog eye disease may benefit humans | Virology News | Scoop.it
Trials in dogs with an inherited eye disease indicate that a gene therapy is ready for development into a treatment for human patients with retinitis pigmentosa.
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Legislation Introduced to Phase Out Dangerous Mink Farms, Reimburse Farmers

Legislation Introduced to Phase Out Dangerous Mink Farms, Reimburse Farmers | Virology News | Scoop.it
US Rep. Adriano Espaillat (D-NY) has introduced legislation to phase out US mink farms within one year and establish a grant program to reimburse farmers for the full value of their operations.
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Did 'deleted' bits of genetic info make us human?

Did 'deleted' bits of genetic info make us human? | Virology News | Scoop.it
The loss of about 10,000 bits of genetic information over the course of our evolutionary history differentiates humans from chimpanzees.
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New variant could cause major covid wave, experts warn White House 

New variant could cause major covid wave, experts warn White House  | Virology News | Scoop.it
Experts reached a consensus that there’s a roughly 20 percent chance during the next two years of an outbreak rivaling the onslaught of illness from omicron.
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Vaccine safety and effectiveness are settled science

Vaccine safety and effectiveness are settled science | Virology News | Scoop.it
Anti-vaccine activists always want a "debate" about vaccine safety and effectiveness, but it is already settled science based on evidence.
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