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Cross-reactive immunity potentially drives global oscillation and opposed alternation patterns of seasonal influenza A viruses

Cross-reactive immunity potentially drives global oscillation and opposed alternation patterns of seasonal influenza A viruses | Virology News | Scoop.it
Several human pathogens exhibit distinct patterns of seasonality and circulate as pairs. For instance, influenza A virus subtypes oscillate and peak during winter seasons of the world’s temperate climate zones.
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
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Spontaneous hydrogen peroxide may explain flu seasonality

Spontaneous hydrogen peroxide may explain flu seasonality | Virology News | Scoop.it
Further investigation into the spontaneous formation of hydrogen peroxide from water may explain why flu cases peak in winter.
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Interesting: makes some assumptions that are not as general as they think (LMICs will not tend to heat houses like the US does), but thinking of humid air interacting with surfaces as producing natural disinfectants is quite intriguing?
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Reinfection will be part of the pandemic for months to come. Each repeat illness raises the risk of long COVID

Reinfection will be part of the pandemic for months to come. Each repeat illness raises the risk of long COVID | Virology News | Scoop.it
SARS-CoV-2 is not the first virus to cause unexplained chronic illness, but the sheer size of this pandemic means more people will develop long COVID.
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Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution...
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Lung proteins can aid or hamper SARS-CoV-2 infections

Lung proteins can aid or hamper SARS-CoV-2 infections | Virology News | Scoop.it
New research is "a step forward in understanding viral infection pathways and paves the way for research toward better treatments in the future."...
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Universal Influenza B Vaccine Induces Broad, Sustained Protection

Universal Influenza B Vaccine Induces Broad, Sustained Protection | Virology News | Scoop.it
A new universal flu vaccine protects against influenza B viruses, offering broad defense against different strains and improved immune protection, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.
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Can bats help prevent the next pandemic?

Can bats help prevent the next pandemic? | Virology News | Scoop.it
Bats can teach us a lot about how to manage, and maybe even prevent, future pandemics, researchers say.
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Nanobody busts into brain cells to unclump proteins

Nanobody busts into brain cells to unclump proteins | Virology News | Scoop.it
Researchers have developed a nanobody that can get through the tough exterior of mouse brain cells and untangle misshapen proteins.
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Comparison of Antiviral Agents for Seasonal Influenza Outcomes in Healthy Adults and Children: A Systematic Review and Network Meta-analysis

In this systematic review and network meta-analysis, all 4 antiviral agents assessed were associated with shortening TTAS; zanamivir was associated with the shortest TTAS, and baloxavir was associated with reduced rate of influenza-related complications.
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Evaluation of a recombinant hemagglutinin expressed in insect cells as an influenza vaccine in young and elderly adults

Healthy subjects <45 years old (young adults) or >65 (elderly adults) were randomized in double-blind fashion to receive intramuscularly subv...
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Microparticles could form self-boosting vaccines

Microparticles could form self-boosting vaccines | Virology News | Scoop.it
New research suggests microparticles able to release their payloads at different times could form the basis of self-boosting vaccine courses.
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Do animals dream? This evidence says yes

Do animals dream? This evidence says yes | Virology News | Scoop.it
Animals really do dream, according to a new book on the science of consciousness. Hear a podcast interview with the author.
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New combo therapies could stop HIV from escaping

New combo therapies could stop HIV from escaping | Virology News | Scoop.it
Carefully designed cocktails of antibodies could help treat HIV while reducing the chance that it evolves to "escape" treatment, researchers say.
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1957-1958 Pandemic (H2N2 virus) | Pandemic Influenza (Flu) 

1957-1958 Pandemic (H2N2 virus) | Pandemic Influenza (Flu)  | Virology News | Scoop.it
Everything you need to know about the flu illness, including symptoms, treatment and prevention.
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Moderna takes mRNA influenza candidate into Phase 3 trial

Moderna takes mRNA influenza candidate into Phase 3 trial | Virology News | Scoop.it
Moderna has dosed the first participants in a Phase 3 study of the company’s seasonal influenza vaccine candidate, mRNA-1010....
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How Long Can the Coronavirus Keep Reinfecting Us?

How Long Can the Coronavirus Keep Reinfecting Us? | Virology News | Scoop.it
No one knows exactly what this will look like—only that it’s guaranteed to keep happening.
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Virologist: Monkeypox genome doesn't explain outbreak

Virologist: Monkeypox genome doesn't explain outbreak | Virology News | Scoop.it
"There are no new, large mutations that could account for the change in [monkeypox] transmission," says virologist Heather Koehler.
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Hippo pathway stops moles turning into deadly melanomas

Hippo pathway stops moles turning into deadly melanomas | Virology News | Scoop.it
A study that clarifies how some harmless moles grow into deadly melanomas could lead to new drug targets for the successful treatment of cancer.
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Quick loss of smell predicts dementia brain changes

Quick loss of smell predicts dementia brain changes | Virology News | Scoop.it
A rapid decline in sense of smell during a period of normal cognition predicted multiple features of Alzheimer's disease, report researchers.
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Thousands of dead migrant seabirds wash up on Canada shore, avian flu suspected

Thousands of dead migrant seabirds wash up on Canada shore, avian flu suspected | Virology News | Scoop.it
The Canadian Food Inspection Agency has confirmed 13 positive cases of highly pathogenic avian influenza in Newfoundland since May...
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What you should know about monkeypox

What you should know about monkeypox | Virology News | Scoop.it
Amid a steady rise in monkeypox cases worldwide, an expert explains how the virus is transmitted, who is at risk, and how vaccines can control the spread.
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COVID vax patch beats needles for fighting variants

COVID vax patch beats needles for fighting variants | Virology News | Scoop.it
A new patch "has the potential to offer a new—and more effective—weapon in our arsenal, at a time where new variants are mutating at a rapid rate."...
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Genetic diversity in the capsid protein of Porcine circovirus type 3 in Vietnam from 2018 to 2019 

Porcine circovirus type 3 (PCV3) was first detected in 2016 and has been recorded in many pig-producing countries around the world. PCV3 was quickly reported in Vietnamese pig farms. PCV3 was found in complex cases with multiple clinical syndromes in swine.
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Global Monkeypox Vaccine Race Sparks Fears That Poorer Nations Will Lose Out

A scramble for monkeypox vaccines is under way, with 35 countries vying for access to the 16.4m doses that exist so far, according to the World Health...
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FEARS?? They're losing out already!!
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Peel-off trick might pave the way for solar cell windows

Peel-off trick might pave the way for solar cell windows | Virology News | Scoop.it
"In principle, we can now scale semitransparent organic solar cells to two meters by two meters, which brings our windows much closer to reality."...
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Adeno-associated virus 2 infection in children with non-A-E hepatitis

An outbreak of acute hepatitis of unknown aetiology in children was first reported in Scotland in April 2022.1 Cases aged <16 years have since been identified in 35 countries.2 Here we report a detailed investigation of 9 early cases and 58 control subjects. Using next-generation sequencing and real-time PCR, adeno-associated virus 2 (AAV2), was detected in the plasma of 9/9 and liver of 4/4 patients but in 0/13 sera/plasma of age-matched healthy controls, 0/12 children with adenovirus (HAdV) infection and normal liver function and 0/33 children admitted to hospital with hepatitis of other aetiology. AAV2 typically requires a coinfecting ‘helper’ virus to replicate, usually HAdV or a herpesvirus. HAdV (species C and F) and human herpesvirus 6B (HHV6B) were detected in 6/9 and 3/9 affected cases, including 3/4 and 2/4 liver biopsies, respectively. The class II HLA-DRB1*04:01 allele was identified in 8/9 cases (89%), compared with a background frequency of 15.6% in Scottish blood donors, suggestive of increased susceptibility in affected cases. Acute non-A-E paediatric hepatitis is associated with the presence of AAV2 infection, which could represent a primary pathogen or a useful biomarker of recent HAdV or HHV6B infection. Population and mechanistic studies are required to explore these findings further.
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