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The Prevalence of Novel Porcine Circovirus Type 3 (PCV3) Isolates in Pig Farms in China.

The emerging porcine circovirus type 3 (PCV3) has been reported in Chinese swine herds since 2017. We performed a nationwide investigation on the prevalence of ...
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Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
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The Spread and Scope of Anti-Vaccine Sentiment and Misinformation in News and Social Media

An important note on language: The Health Misinformation Working Group researchers acknowledge that there are implications of using terms like ‘anti-vaccine’ or ‘anti-vax’ to the broader academic and general discourse. In general, we utilize the terms ‘vaccine hesitancy’ or ‘vaccine hesitant’ to describe the spectrum of concerns in perspectives that individuals may have towards vaccinations. The World Health Organization classifies vaccine hesitancy as: “a behavior, influenced by a number of factors including issues of confidence (do not trust a vaccine or a provider), complacency (do not perceive a need for a vaccine or do not value the vaccine), and convenience (access)” (WHO, 2014, as cited by Edwards et al., 2016). Using polarizing terminology such as ‘pro-vaccine’ or ‘anti-vaccine’ in this context is likely not reflective of the true landscape of perspectives, and can contribute negatively to perceptions of what may or may not be prevalent norms. If we use the term ‘anti-vaccine’, it is purely to reference content that can be identified as disinformation or misinformation explicitly against vaccination. Each year, more than 300,000 women die of cervical cancer, and more than half a million women are diagnosed. Nine in 10 women who die from cervical cancer are in poor countries, with the survival rate ranging between 33 and 77%; the overall numbers and disparity are unacceptable, especially given they can be minimized through one important intervention: Human Papillomavirus (HPV) vaccination. Yet hesitancy around the HPV vaccine is widespread. 

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Broadly resistant HIV-1 against CD4-binding site neutralizing antibodies

Broadly resistant HIV-1 against CD4-binding site neutralizing antibodies | Virology News | Scoop.it
Author summary Recently identified broadly neutralizing antibodies (bnAbs) show great potential for clinical interventions against HIV-1 infection. Among the bnAbs isolated to date, those targeting the CD4bs are the most abundant and thoroughly studied as they disrupt the crucial step of viral...
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Discovery could lead to better maternal vaccines

Discovery could lead to better maternal vaccines | Virology News | Scoop.it
A new discovery could lead to safer and more effective maternal vaccines, which protect pregnant women and their newborns from dangerous infections.
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Quadrivalent human papillomavirus vaccination in girls and the [LACK OF] risk of autoimmune disorders

RESULTS: The study cohort consisted of 290 939 girls aged 12-17 years who were eligible for vaccination between 2007 and 2013. There was no significant risk for developing an autoimmune disorder following HPV4 vaccination (n = 681; rate ratio 1.12, 95% CI 0.85-1.47), and the association was unchanged by a history of immune-mediated disorders and time since vaccination. Exploratory analyses of individual autoimmune disorders found no significant risks, including for Bell palsy (n = 65; rate ratio 1.73, 95% CI 0.77-3.89), optic neuritis (n = 67; rate ratio 1.57, 95% CI 0.74-3.33) and Graves disease (n = 47; rate ratio 1.55, 95% CI 0.92-2.63). 


 INTERPRETATION: We did not observe an increased risk of autoimmune disorders following HPV4 vaccination among teenaged girls. These findings should reassure parents and health care providers.

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An evaluation of the 2016 influenza vaccination in pregnancy campaign in NSW, Australia

An evaluation of the 2016 influenza vaccination in pregnancy campaign in NSW, Australia | Virology News | Scoop.it

Introduction Pregnant women are at increased risk of suffering serious complications from influenza.1 Influenza can also have adverse effects on the fetus, and increases the risk of premature birth, stillbirth and pregnancy loss.1,2 A variety of overseas3,4 and Australian studies5-8 have shown that vaccinating pregnant women is safe and effective in reducing these complications. Pregnant women have been classified as the group of highest priority for seasonal influenza vaccination programs by the World Health Organization since 2012.9 Influenza vaccination in pregnancy has been recommended by the Australian Technical Advisory Group on Immunisation since March 2000, and has been funded under the National Immunisation Program since January 2010.10 Vaccination is available through general practitioners (GPs) and some antenatal clinics. Despite being strongly recommended, vaccine uptake is suboptimal. Factors identified as contributing to poor uptake include lack of awareness by pregnant women, lack of provider recommendation, and maternal concerns about safety and efficacy for mother and child.

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Scientists develop potential Alzheimer's vaccine, successfully treat mice 

Scientists develop potential Alzheimer's vaccine, successfully treat mice  | Virology News | Scoop.it
A team of researchers at the University of New Mexico is developing a new vaccine that they hope will be able to prevent Alzheimer's disease in humans after seeing promising results in tests with...
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Don’t panic. There is no influenza “outbreak” –

Don’t panic. There is no influenza “outbreak” – | Virology News | Scoop.it
There is no influenza outbreak in South Africa, other than the normal increase of cases expected during winter, the National Institute for Communicable Diseases (NICD) has said...
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Severe Chickenpox Outbreak Hits School Where Many Parents Refuse Vaccines

Severe Chickenpox Outbreak Hits School Where Many Parents Refuse Vaccines | Virology News | Scoop.it
A significant number of parents at North Carolina's Asheville Waldorf School have expressed religious objections to vaccines.
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Swine fever ravages China’s pig farms, driving up pork prices worldwide

Swine fever ravages China’s pig farms, driving up pork prices worldwide | Virology News | Scoop.it
China has ordered a mass cull of pigs in order to contain the swine fever epidemic, but it could take years for the pork industry to recover. In the U.S., the shortage means paying more for bacon, ham and other foods.
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Anti-Vaccine Movement Labelled A "Contagious Disease"

Anti-Vaccine Movement Labelled A "Contagious Disease" | Virology News | Scoop.it
Health experts are blaming the rapidly increasing spread of measles, which was previously rare because of a high vaccination rate, on the worldwide anti-vaccine movement.
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Doctors urge seniors to get vaccinated agains pneumonia

Doctors urge seniors to get vaccinated agains pneumonia | Virology News | Scoop.it
Older Australians urged to get vaccinated against 'killer lung infection'.
Ed Rybicki's insight:
And South Africans...!
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Australia facing worst flu season since 2009 

Australia facing worst flu season since 2009  | Virology News | Scoop.it
Australia facing worst flu season since 2009 | 7.30 So far this year 139 Australians have died from the flu, according to the federal department of health.That’s three times more than averag…...
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Rakesh Yashroy's comment, 9 June, 00:50
My suspicion: 'if you tame the nephew (vaccinate against common cold) his uncle may attack with a deadly blow. There is no need to steal the natural habitat of common cold group of viruses for selling vaccines against irritating cold, as that might prepare human body to fight deadlier pathogens.
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Go go gadget glycoprotein!: HSV-1 draws on its sizeable glycoprotein tool kit to customize its diverse entry routes

Go go gadget glycoprotein!: HSV-1 draws on its sizeable glycoprotein tool kit to customize its diverse entry routes | Virology News | Scoop.it

Citation: Hilterbrand AT, Heldwein EE (2019) Go go gadget glycoprotein!: HSV-1 draws on its sizeable glycoprotein tool kit to customize its diverse entry routes. PLoS Pathog 15(5): e1007660. https://doi.org/10.1371/journal.ppat.1007660 Editor: Katherine R. Spindler, University of Michigan Medical School, UNITED STATES Published: May 9, 2019 Copyright: © 2019 Hilterbrand, Heldwein. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: The work on HSV-1 entry in the Heldwein laboratory is supported by NIH grant 1R21AI140711-01 (EEH) and a Faculty Scholar grant from Howard Hughes Medical Institute (EEH). ATH is supported by the NIH training grant 5T32AI007329-24. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing interests: The authors have declared that no competing interests exist. Introduction: Viruses deploy diverse entry strategies All viruses must enter cells to replicate [1]. Entry is thus the first hurdle a virus must overcome for a successful infection. Given the astonishing diversity of viruses that infect mammals alone—hundreds of thousands of different viruses according to some estimates [2]—it is unsurprising that their entry routes into cells are just as diverse. A major structural distinction that dictates the entry mode is the presence or absence of a lipid bilayer surrounding the viral nucleocapsid, which defines a virus as enveloped or nonenveloped, respectively. 

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Functional paralysis of human natural killer cells by alphaherpesviruses

Functional paralysis of human natural killer cells by alphaherpesviruses | Virology News | Scoop.it
Author summary Natural killer (NK) cells–as their name implies–are the immune system’s ready to respond ‘killers’, being able to help control viral infection by cytolytic killing of infected cells and secretion of pro-inflammatory cytokines to activate and direct the immune response.
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Microbiota-mediated disease resistance in plants

Microbiota-mediated disease resistance in plants | Virology News | Scoop.it

It is now critical to further develop bottom-up experimental approaches to improve our understanding of dominance and modularity of desirable traits within SynComs. Cataloguing such knowledge on microbial traits and their behavior in a community context will allow the establishment of a microbial toolbox for microbiota-mediated pathogen protection and the rational design of SynComs with modular functions related to MMI and DMC. In parallel or in combination with this cataloguing, microbial network inference will play a key role in identifying candidate biocontrol taxa and in the design of SynComs with stable and predictable outcome in the field. In addition to the mentioned benefits for direct application in the field, this approach is likely to provide insights into the following unresolved fundamental questions: (1) Can we detect phylogenetic signals for MMI and DMC traits that could be used to predict beneficial outcomes for the plant host? (2) Do immunity-modulating microbes act through similar or different immune pathways? And (3) as a consequence of the previous question, do the identified MMI and DMC traits act independently, synergistically, or antagonistically?

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Chinese clinic forced to reassure people HIV vaccine trials won't give them the virus, China News

Chinese clinic forced to reassure people HIV vaccine trials won't give them the virus, China News | Virology News | Scoop.it
China News - Read more at AsiaOne...
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The Prevalence of Novel Porcine Circovirus Type 3 (PCV3) Isolates in Pig Farms in China.

The emerging porcine circovirus type 3 (PCV3) has been reported in Chinese swine herds since 2017. We performed a nationwide investigation on the prevalence of ...
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New York City closes 10th Jewish school for violating vaccine order 

New York City closes 10th Jewish school for violating vaccine order  | Virology News | Scoop.it
Williamsburg institution was still admitting students and faculty who were not immunized against the measles, city official says...
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Experts advise people to get flu shot as flu cases rapidly rise in Australia

Our flu season has arrived early, and it has health authorities concerned. The case numbers are looking a lot like 2017's deadly winter, which was our worst ...
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LA BioMed Scientists Make Breakthrough on Potential Vaccine For Deadly Fungal Infection 

LA BioMed Scientists Make Breakthrough on Potential Vaccine For Deadly Fungal Infection  | Virology News | Scoop.it
LOS ANGELES — Researchers from the Los Angeles Biomedical Research Institute (LA BioMed) and Vitalex Biosciences (a spinoff company of LA BioMed) helped lead an experiment that successfully immunized mice against mucormycosis, a fungal infection that is often fatal, potentially paving the way for the development of an immunotherapy for humans. Mucormycosis, which has mortality rates ranging from 50% to 100%, has been on the rise at surgical transplant centers in the United States in recent years, and has jumped 70% in France in a recent nine-year period. It is caused by several fungi in the Mucorales family, including Rhizopus, Mucor and Lichtheimia.  Dr. Ashraf Ibrahim of LA BioMed and the founder of Vitalex Biosciences led a team of 12-scientists that developed polyclonal and monoclonal antibodies against conserved peptide regions of one protein, CotH3, which is universally present in Mucorales.  CotH3 protein allows the fungus to invade mouse/human cells to cause infection.  A 30-µg dose of one of the monoclonal antibodies, C2, significantly reduced mortality in neutropenic or diabetic mice infected with any of the organisms that cause mucormycosis. Even more impressively, those treated with the C2 antibody combined with a common antifungal drug almost completely survived the infection and appeared healthy at the termination of the study, with no residual fungi found in their lungs or brains. The scientists believe this could lead to the development of life-saving immunotherapies for humans at risk of contracting mucormycosis. “We are proud of our investigators for a discovery that could potentially save many lives,” said David Meyer, PhD, President and CEO, LA BioMed. “Hospital-acquired infections are a growing problem affecting those least able to fight them. This type of highly impactful research is what our institute is all about.”
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Virus which is the most common causes of gastroenteritis in children drops by 72% since vaccine rollout

Virus which is the most common causes of gastroenteritis in children drops by 72% since vaccine rollout | Virology News | Scoop.it
Rotavirus disease is the most common cause of gastroenteritis in children.
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FAO names first reference centre for animal influenza in Asia

FAO names first reference centre for animal influenza in Asia | Virology News | Scoop.it
07/03/2013 Bangkok, Thailand The Food and Agriculture Organization of the United Nations announced today that earlier this week it designated the Harbin Veterinary Research Institute (HVRI), in the Heilongjiang Province of the People’s Republic of China (PR China), as the FAO reference centre for...
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The first reptilian circovirus identified infects gut and liver tissues of black-headed pythons

Vet Res. 2019 May 16;50(1):35. doi: 10.1186/s13567-019-0653-z.
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Risk assessment: Who is at risk of measles in the EU/EEA?

Risk assessment: Who is at risk of measles in the EU/EEA? | Virology News | Scoop.it
A large epidemic of measles has affected the EU/EEA Member States in the past three years, with 44 074 cases reported to ECDC by 30 Member States between 1 January 2016 and 31 March 2019.
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Co-circulation of genetically distinct highly pathogenic avian influenza A clade 2.3.4.4 (H5N6) viruses in wild waterfowl and poultry in Europe and... - PubMed - NCBI

Virus Evol. 2019 Apr 22;5(1):vez004. doi: 10.1093/ve/vez004. eCollection 2019 Jan.
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