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Plant pest destruction goes viral

Plant pest destruction goes viral | Virology News | Scoop.it
Fusion of a viral coat protein to an insect-specific neurotoxin delivers the molecule into aphids where it is insecticidal.
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
Curated by Ed Rybicki
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Cann's Principles of Molecular Virology - 7th Edition

Cann's Principles of Molecular Virology - 7th Edition | Virology News | Scoop.it

Cann's Principles of Molecular Virology, - 7th Edition, revised by EP Rybicki. Print Book. ISBN 9780128227848. Now published!!


Instructor review copies: click on this link.

https://protect-za.mimecast.com/s/qU2qCNxKq0i0ZNRQxcmeDdo

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Optimal timing maximizes Paxlovid benefits for treating COVID-19

Optimal timing maximizes Paxlovid benefits for treating COVID-19 | Virology News | Scoop.it
Researchers have described the optimal timing for COVID-19 patients to take the antiviral, Paxlovid, to get the most benefit from the treatment, according to a study published April 16 in eLife.
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Surfing the Waves of SARS-CoV-2: Analysis of Viral Genome Variants Using an NGS Survey in Verona, Italy

Surfing the Waves of SARS-CoV-2: Analysis of Viral Genome Variants Using an NGS Survey in Verona, Italy | Virology News | Scoop.it
The availability of new technologies for deep sequencing, including next-generation sequencing (NGS), allows for the detection of viral genome variations. The epidemiological determination of SARS-CoV-2 viral genome changes during the pandemic waves displayed the genome evolution and subsequent...
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A Multi-Faceted Binding Assessment of Aptamers Targeting the SARS-CoV-2 Spike Protein

A Multi-Faceted Binding Assessment of Aptamers Targeting the SARS-CoV-2 Spike Protein | Virology News | Scoop.it
The COVID-19 pandemic has underscored the critical need for the advancement of diagnostic and therapeutic platforms. These platforms rely on the rapid development of molecular binders that should facilitate surveillance and swift intervention against viral infections.
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Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections | Virology News | Scoop.it
Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.
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New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations | Virology News | Scoop.it
A tARC-seq approach to precisely determine SARS-CoV-2 mutation frequency.
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Virtual Viruses Reveal Complex Genomic Dynamics

Virtual Viruses Reveal Complex Genomic Dynamics | Virology News | Scoop.it
Researchers used new simulations to obtain the first structures of elusive viruses.
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Engineers muffle invading pathogens with a 'molecular mask'

Engineers muffle invading pathogens with a 'molecular mask' | Virology News | Scoop.it
Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop. Rapidly mutating viruses such as SARS-CoV-2 can blunt their effectiveness and even render them obsolete.
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Giant virus discovered in wastewater treatment plant infects deadly parasite

Giant virus discovered in wastewater treatment plant infects deadly parasite | Virology News | Scoop.it
The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses...
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Producing Commercial-Scale Plant-Based Protein with Genetic Engineering

Producing Commercial-Scale Plant-Based Protein with Genetic Engineering | Virology News | Scoop.it
And there are benefits of plant cell expression systems, notably their impact on the cost of goods sold (COGS).
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Attack and defense in the microverse: How small RNA molecules regulate viral infections of bacteria

Attack and defense in the microverse: How small RNA molecules regulate viral infections of bacteria | Virology News | Scoop.it
Viruses need hosts. Whether it's measles, the flu or coronavirus, viral pathogens cannot multiply or infect other organisms without the assistance of their hosts' cellular infrastructure. However, humans are not the only ones affected by viruses: animals, plants and even microorganisms can all...
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Why there may be oceans inside dwarf planets beyond Pluto—and what this means for the likely abundance of life

Why there may be oceans inside dwarf planets beyond Pluto—and what this means for the likely abundance of life | Virology News | Scoop.it
Earth was long thought to be the only planet in our solar system with an ocean, but it is beginning to look as though there are underground oceans inside even the most surprising icy bodies.
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What four decades of canned salmon reveal about marine food webs

What four decades of canned salmon reveal about marine food webs | Virology News | Scoop.it
Alaskan waters are a critical fishery for salmon. Complex marine food webs underlie and sustain this fishery, and scientists want to know how climate change is reshaping them. But finding samples from the past isn't easy.
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Genome surveillance of pathogens 

Whole genome sequencing was crucial in combatting the COVID-19 pandemic—from real-time monitoring of SARS-CoV-2 spread and evolution, to guiding public health responses, treatments, and vaccine development.

Building on this, Struelens et al. advocate for integration of pathogen genomic data and epidemiological data into globally interconnected One Health surveillance systems. Their lead article outlines necessary enablers for deploying real-time genomic surveillance of pathogens and antimicrobial resistance worldwide—including data-sharing platforms, new sequencing technologies, and cross-sector collaborations.

Read the article in Frontiers in Science: https://www.frontiersin.org/journals/science/articles/10.3389/fsci.2024.1298248/full

Citation:
Struelens MJ, Ludden C, Werner G, Sintchenko V, Jokelainen P and Ip M. Real-time genomic surveillance for enhanced control of infectious diseases and antimicrobial resistance. Front Sci (2024) 2:1298248. doi: 10.3389/fsci.2024.1298248
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Advax-SM™-Adjuvanted COBRA (H1/H3) Hemagglutinin Influenza Vaccines

Advax-SM™-Adjuvanted COBRA (H1/H3) Hemagglutinin Influenza Vaccines | Virology News | Scoop.it
Adjuvants enhance immune responses stimulated by vaccines. To date, many seasonal influenza vaccines are not formulated with an adjuvant. In the present study, the adjuvant Advax-SM™ was combined with next generation, broadly reactive influenza hemagglutinin (HA) vaccines that were designed using...
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Mechanisms by Which SARS-CoV-2 Invades and Damages the Central Nervous System: Apart from the Immune Response and Inflammatory Storm, What Else Do We Know?

Mechanisms by Which SARS-CoV-2 Invades and Damages the Central Nervous System: Apart from the Immune Response and Inflammatory Storm, What Else Do We Know? | Virology News | Scoop.it
Initially reported as pneumonia of unknown origin, COVID-19 is increasingly being recognized for its impact on the nervous system, despite nervous system invasions being extremely rare. As a result, numerous studies have been conducted to elucidate the mechanisms of nervous system damage and...
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Vascular Alterations following COVID-19 Infection: A Comprehensive Literature Review

Vascular Alterations following COVID-19 Infection: A Comprehensive Literature Review | Virology News | Scoop.it
SARS-CoV-2, the causative agent of the ongoing COVID-19 pandemic, has revealed a broader impact beyond the respiratory system, predominantly affecting the vascular system with various adverse manifestations.
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Checkpoint inhibitor-expressing lentiviral vaccine suppresses tumor growth in preclinical cancer models 

Checkpoint inhibitor-expressing lentiviral vaccine suppresses tumor growth in preclinical cancer models  | Virology News | Scoop.it

WHAT IS ALREADY KNOWN ON THIS TOPICCancer can be controlled by T cells that recognize tumor antigens. Checkpoint immunotherapy increases the effectiveness of T cells in controlling cancer by restoring function to exhausted T cells. In a significant fraction of patients, immunotherapy is not successful, most likely because there are not a sufficient number of T cells that target tumor antigens. Dendritic cells present tumor antigen epitopes to T cells on major histocompatibility complex class I but may not activate a sufficient number of antitumor T cells. Therapeutic dendritic cell vaccines that present tumor antigen to T cells have seen some clinical success. Lentiviral vectors provide a means to achieve long-term expression of transgenes by virtue of their ability to integrate into the host cell chromosome.

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Long COVID Rates Elevated in Men With Type 2 Diabetes

Long COVID Rates Elevated in Men With Type 2 Diabetes | Virology News | Scoop.it
The opposite was seen in women when compared with matched control individuals without diabetes.
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COVID-19 virus disrupts protein production: Researcher discusses her recent findings

COVID-19 virus disrupts protein production: Researcher discusses her recent findings | Virology News | Scoop.it
Despite huge advances in our understanding of COVID-19 over the past four years, the disease is still very much among us—and there remains a lot to learn.
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Vast DNA tree of life for plants revealed by global science team using 1.8 billion letters of genetic code

Vast DNA tree of life for plants revealed by global science team using 1.8 billion letters of genetic code | Virology News | Scoop.it
A new paper published today (April 24) in the journal Nature by an international team of 279 scientists led by the Royal Botanic Gardens, Kew presents the most up-to-date understanding of the flowering plant tree of life.
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Enhanced CRISPR method enables stable insertion of large genes into the DNA of higher plants

Enhanced CRISPR method enables stable insertion of large genes into the DNA of higher plants | Virology News | Scoop.it
Scientists at the Leibniz Institute of Plant Biochemistry (IPB) have succeeded for the first time in stably and precisely inserting large gene segments into the DNA of higher plants very efficiently.To do this, they optimized the gene-editing method CRISPR/Cas, commonly known as "genetic scissors."...
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Self-assembly of complex systems: Hexagonal building blocks are better

Self-assembly of complex systems: Hexagonal building blocks are better | Virology News | Scoop.it
Complex systems in nature, like their synthetic counterparts in technology, comprise a large number of small components that assemble of their own accord through molecular interactions. Gaining a better understanding of the principles and mechanisms of this self-assembly is important for the...
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How plants heal wounds: Mechanical forces guide direction of cell division

How plants heal wounds: Mechanical forces guide direction of cell division | Virology News | Scoop.it
Plants are made up of very rigid cells. Much like bricks in a wall, this feature gives them the structural support to maintain their shape and to stand upright against gravity. However, just like any living organism, plants can be injured, for instance, by wind or animal grazing.
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New research traces the fates of stars living near the Milky Way's central black hole

New research traces the fates of stars living near the Milky Way's central black hole | Virology News | Scoop.it
Despite their ancient ages, some stars orbiting the Milky Way's central supermassive black hole appear deceptively youthful. But unlike humans, who might appear rejuvenated from a fresh round of collagen injections, these stars look young for a much darker reason.
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Mapping lava tubes on the moon and Mars from space

Mapping lava tubes on the moon and Mars from space | Virology News | Scoop.it
Sometimes, all you need for a new discovery is some creative math. That was the case for a new paper by Edward Williams and Laurent Montési of the University of Maryland's Department of Geology. They released a brief paper at the Lunar and Planetary Science Conference (LPSC 2024) last month that...
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