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Emergency response vaccines for H5N1 influenza in South Africa

Emergency response vaccines for H5N1 influenza in South Africa | Virology News | Scoop.it
Our group has been working for some time now - since 2006, in fact - on investigating the feasibility of providing South (and southern) Africa with emergency response pandemic influenza vaccines.  ...
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
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Human infection With a Novel Reassortment Avian Influenza A H3N8 Virus: An Epidemiological Investigation Study

Human infection With a Novel Reassortment Avian Influenza A H3N8 Virus: An Epidemiological Investigation Study | Virology News | Scoop.it
Preprint: Human infection With a Novel Reassortment Avian Influenza A H3N8 Virus: An Epidemiological Investigation Study (https://afludiary.blogspot.com/2022/06/preprint-human-infection-with-novel.html) https://blogger.googleusercontent.com/img/a/AVvXsEgav8i-O7l939Gp7pMQmrw0OD_Uyy1zTMVebnXiSuyIHGdE6fmJ0U8-0Meec4nspCyaR1dzGWO2Ig...
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Characterization of a dynamic self-replicating mammalian expression vector based on the circular ssDNA genome of beak and feather disease virus

In vivo nucleic expression technologies using DNA or mRNA offer several advantages for recombinant gene expression. Their inherent ability to generate natively expressed recombinant proteins and antigens allows these technologies to mimic foreign gene expression without infection.
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No enlightened self-interest here. No, none at all! B-)
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Evidence of surface contamination in hospital rooms occupied by patients infected with monkeypox, Germany, June 2022

The extent of monkeypox virus environmental contamination of surfaces is unclear. We examined surfaces in rooms occupied by two monkeypox patients on their fourth hospitalisation day. Contamination with up to 105 viral copies/cm2 on inanimate surfaces was estimated by PCR and the virus was...
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Has Epizootic Become Enzootic? Evidence for a Fundamental Change in the Infection Dynamics of Highly Pathogenic Avian Influenza in Europe, 2021

Phylogenetic evidence from the recent resurgence of high-pathogenicity avian influenza (HPAI) virus subtype H5N1, clade 2.3.4.4b, observed in European wild birds and poultry since October 2021, suggests at least two different and distinct reservoirs.
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Beijing Mandates COVID Vaccine Requirements As Cases Grow Nationwide

Beijing Mandates COVID Vaccine Requirements As Cases Grow Nationwide | Virology News | Scoop.it
BEIJING — The Chinese capital will require Covid vaccinations for entering gyms and some other venues, the first such mandate in the country.
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Influenza and pneumococcal vaccination and the risk of COVID-19: A systematic review and meta-analysis | medRxiv

Influenza and pneumococcal vaccination and the risk of COVID-19: A systematic review and meta-analysis | medRxiv | Virology News | Scoop.it
medRxiv - The Preprint Server for Health Sciences...
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There Is No ‘Back to Normal’ After Covid. A Q&A With Hitoshi Oshitani - Bloomberg

There Is No ‘Back to Normal’ After Covid. A Q&A With Hitoshi Oshitani - Bloomberg | Virology News | Scoop.it
A Q&A with top Japanese virologist Hitoshi Oshitani about reopening tourism, future strains of Covid and the post-pandemic world.
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Song swap indicates humpback whales trade culture

Song swap indicates humpback whales trade culture | Virology News | Scoop.it
Observations of song learning among humpback whales indicate "a level of 'cultural transmission' beyond any observed non-human species."...
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Reactivation of varicella-zoster virus following mRNA COVID-19 vaccination in a patient with moderately differentiated adenocarcinoma of rectum

Herpes zoster which is the reactivation of varicella-zoster virus, a pathogenic human alpha-herpes virus, following primary infection or chicken pox, is known to occur especially in advanced age an...
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GSK’s new vaccine hire looks beyond COVID in quest for next hit: 'The potential is there to really make a much better flu vaccine'

GSK’s new vaccine hire looks beyond COVID in quest for next hit: 'The potential is there to really make a much better flu vaccine' | Virology News | Scoop.it
GSK Plc is planning to launch a COVID shot that comes almost two years after Pfizer Inc. took the world by storm. For Phil Dormitzer, it’s a reminder of why he was hired at the UK drugmaker: to help return its immunization business to the top after it stumbled during the pandemic.
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Live attenuated Salmonella enterica serovar Choleraesuis vector delivering virus-like particles induces a protective immune response against porcine circovirus type 2 in mice

The virus-like particles (VLPs) of porcine circovirus type 2 (PCV2) is an attractive vaccine candidate that retains the natural conformation of the virion but lacks the viral genome to replicate, thus balancing safety and immunogenicity.
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Whole genome, transcriptome, smallRNAome and methylome profiling during tomato-geminivirus interaction

Preguntas frecuentesManual de usoDerechos de autorContacto/Sugerencias Whole genome, transcriptome, smallRNAome and methylome profiling during tomato-geminivirus interaction Autor Romero-Rodríguez, Beatriz; Kriznik, Maja; Morilla, Ian; Petek, Marko; Jiao, Chen; [et al.] Fecha 2022 Palabras clave Virus fitopatógenos; Tomates - Enfermedades y plagas Resumen Geminiviruses constitute the largest family of plant-infecting viruses with small, single- stranded DNA genomes that replicate through double-stranded DNA intermediates. Because of their limited coding capacity, geminiviruses use plant nuclear machinery to amplify their genomes, which are packaged into nucleosomes forming chromatin as multiple circular minichromosomes. Thus, viral minichromosomes must encounter the nuclear pathways that regulate host gene expression and chromatin states. DNA methylation and post-transcriptional gene silencing play critical roles in controlling infection of geminiviruses and this pathogen can counteract these host defense mechanisms and promote its infectivity. Tomato Yellow Leaf Curl Virus (TYLCV) belongs to the Begomovirus genus and is transmitted by the whitefly Bemisia tabaci. With only seven viral proteins, TYLCV must create a proper environment for viral replication, transcription, and propagation. Behind the apparent simplicity of geminiviruses lies a complex network of molecular interactions with their host and their natural vector, which induces a wide variety of transcriptional, post-transcriptional and chromatin changes in the host. To better understand this virus-host interaction at a genetic and epigenetic level we carried out a global approach of the TYLCV-tomato interaction to generate integrated single-base resolution maps by Next-Generation Sequencing of the transcriptome, smallRNAome and methylome of the pathogen and the host. Total RNA and DNA was extracted from tomato–infected plants (three biological replicates) and analysed at 2, 7, 14 and 21-day post-infection (dpi). Analysis of the changes in host transcription during the infection and its correlation with changes in sRNA profiles (microRNA and phasiRNA) and DNA methylation patterns will be presented and discussed. URI https://hdl.handle.net/10630/24432 Compartir Mostrar el registro completo del ítem Ficheros abs_libro_omics.pdf (37.69Kb) Colecciones BCGF - Contribuciones a congresos científicos Estadísticas Ver Estadísticas de uso Buscar en Dimension
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All the -omes!! This should make That Person Who Hates -Omes happy??
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Listeria-based booster improves vaccine's protection against recurring colon cancer

Listeria-based booster improves vaccine's protection against recurring colon cancer | Virology News | Scoop.it
Colorectal, pancreatic, esophageal and stomach cancers—some of the deadliest kinds of cancer—have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.
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Can the Flu Vaccine Help Keep Older Minds Sharp?

Can the Flu Vaccine Help Keep Older Minds Sharp? | Virology News | Scoop.it
Flu vaccination has been linked to a 40% lower risk of Alzheimer’s disease in older adults, according to a new study.
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We could wish??
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Expanding Capacity for Vaccines Against Covid-19 and Future Pandemics: A Review of Economic Issues

Expanding Capacity for Vaccines Against Covid-19 and Future Pandemics: A Review of Economic Issues | Virology News | Scoop.it
Founded in 1920, the NBER is a private, non-profit, non-partisan organization dedicated to conducting economic research and to disseminating research findings among academics, public policy makers, and business professionals.
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High number of seal deaths linked to bird flu, feds say

High number of seal deaths linked to bird flu, feds say | Virology News | Scoop.it
An unusual number of seals are becoming stranded and dying off Maine this summer, and avian influenza is to blame, the federal government said.
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Could you inhale a future COVID vaccine?

Could you inhale a future COVID vaccine? | Virology News | Scoop.it
An Inhalable COVID-19 vaccine tested in a rodent model targets the lungs specifically and effectively. One day, you may be able to self-administer it.
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Roles of Humidity and Temperature in Shaping Influenza Seasonality - PMC

Roles of Humidity and Temperature in Shaping Influenza Seasonality - PMC | Virology News | Scoop.it
Experimental studies in guinea pigs demonstrated that influenza virus transmission is strongly modulated by temperature and humidity. A number of epidemiological studies have followed up on these findings and revealed robust associations between influenza ...
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Ischemic stroke risk may be higher after COVID-19 compared to flu or bacterial pneumonia

Ischemic stroke risk may be higher after COVID-19 compared to flu or bacterial pneumonia | Virology News | Scoop.it
A new study examined electronic health records for approximately half the population of Denmark, looking for people with a diagnosis of COVID-19 or hospitalized with community-acquired pneumonia.
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COVID-19 variant boosters won’t need new clinical trials for clearance, FDA says

COVID-19 variant boosters won’t need new clinical trials for clearance, FDA says | Virology News | Scoop.it
The FDA will rely on data from clinical trials of COVID-19 vaccine boosters against the BA.1 version of the omicron variant to evaluate boosters against the BA.4 and BA.5 variants.
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Universal Flu Vaccine Enters Clinical Trials in Humans 

The test will inoculate 100 volunteers with a vaccine that protected mice from lethal doses of six different flu strains...
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First case in Belgium of circovirus-like particles in the bursae of racing pigeons

This paper reports the first cases of pigeon circovirus infection in Belgium. Five pigeons were necropsied and specific lesions with inclusions bod...
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Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine

Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine | Virology News | Scoop.it
An inhalable virus-like-particle consisting of exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain is stable at room temperature and elicits systemic and mucosal immune responses in small animals.
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Rare thymocyte cells can turn into blood cancer

Rare thymocyte cells can turn into blood cancer | Virology News | Scoop.it
New research clarifies how some people develop T-cell acute lymphoblastic leukemia.
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Covid: Omicron subvariants BA.4 and BA.5 escape antibodies from vaccination and prior infection, studies suggest

Covid: Omicron subvariants BA.4 and BA.5 escape antibodies from vaccination and prior infection, studies suggest | Virology News | Scoop.it
Omicron subvariants BA.4 and BA.5 appear to escape antibody responses among both people who had previous Covid-19 infection and those who have been fully vaccinated and boosted, according to new data from researchers at Beth Israel Deaconess Medical Center, of Harvard Medical School.
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