Get Started for FREE
Sign up with Facebook Sign up with X
I don't have a Facebook or a X account
 Your new post is loading...
Your new post is loading...
Scoop.it!
Novavax Inc. previously responded to concerns about Ebola and Middle East Respiratory Syndrome by making new vaccine candidates. But it has remained mum on Zika virus, until now. 
No comment yet.
Sign up to comment
Scoop.it!
"Transgenic plants present enormous potential as a cost-effective and safe platform for large-scale production of vaccines and other therapeutic proteins. A number of different technologies are under development for the production of pharmaceutical proteins from plant tissues. One method used to express high levels of protein in plants involves the employment of plant virus expression vectors. Plant virus vectors have been designed to carry vaccine epitopes as well as full therapeutic proteins such as monoclonal antibodies in plant tissue both safely and effectively. Biopharmaceuticals such as these offer enormous potential on many levels, from providing relief to those who have little access to modern medicine, to playing an active role in the battle against cancer. This review describes the current design and status of plant virus expression vectors used as production platforms for biopharmaceutical proteins."
And of course, let it not be forgotten that our group has pioneered the use of mastreviruses in this regard: maize streak virus in 1999-2001, and bean yellow dwarf in 2010 and since. Investigation of the potential of maize streak virus to act as an infectious gene vector in maize plants.
High level protein expression in plants through the use of a novel autonomously replicating geminivirus shuttle vector.
...not to mention a treatise on ssDNA virus vectors in plants:
Virus-Derived ssDNA Vectors for the Expression of Foreign Proteins in Plants.
Scoop.it!
Animation of the mechanism of an influenza virus and how Crucell's antibodies target the HA1 proteins on the virus and prevent further spread of influenza.
Might be an advert, but it's one of the nicest animations of flu virus entry and neutralisation that I've ever seen. In fact, it's the ONLY one!
|
Scoop.it!
Could the next big animal-human disease wipe us out?
I do so love a good scare story. Especially about viruses.
Scoop.it!
The worldwide emergence of ‘superbugs’ and a dry antibiotic pipeline threaten modern society with a return to the preantibiotic era. Phages – the viruses of bacteria – could help fight antibiotic-resistant bacteria. Phage therapy was first attempted in 1919 by Felix d’Herelle and was commercially developed in the 1930s before being replaced by antibiotics in most of the western world.
I have long had a fascination for the use of phages to treat disease - and now it looks like it's the new-new wave of the future, as antibiotics begin to fail. Image courtesy of Russell Kightley Media
Scoop.it!
Rabies is an avertable viral disease caused by the rabid animal to the warm blooded animals (zoonotic) especially human. Rabies occurs in more than 150 countries and territories.
A very useful review on something that is an underestimated problem in developing countries. Image courtesy of Russell Kightley Media (http://www.rkm.com.au)
|
