Viruses, Immunology & Bioinformatics from 4Virology.net at UVic
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Plant-Based Vaccines, Antibodies and Biologics 5: Part 1

Plant-Based Vaccines, Antibodies and Biologics 5: Part 1 | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
Plant-Based Vaccines, Antibodies and Biologics: the 5th Conference Verona, Italy, June 2013 The return of this biennial meeting to Verona – the third time it has been held here – was a welcome chan...
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Viruses, Immunology & Bioinformatics from 4Virology.net at UVic
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
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It's a group effort - the curators:

It's a group effort - the curators: | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it

get in touch if you want to help curate this topic

Bemol Sido's comment, October 10, 2015 5:28 AM
Thanks. Nice.
Bwana Moses's comment, May 25, 2016 6:13 AM
Great work. Keep it going.
Bwana Moses's comment, March 7, 2017 12:46 PM
Thank You.
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Feds to invest $192M to help create and produce coronavirus vaccine, says Trudeau - Video

Feds to invest $192M to help create and produce coronavirus vaccine, says Trudeau - Video | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
Justin Trudeau says the federal government is planning to invest $192 million to help create and produce vaccines for COVID-19. The prime minister says money will be distributed to a number of different companies and universities.

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A deadly virus is spreading from state to state and has infected 19 million Americans so far. It's influenza

A deadly virus is spreading from state to state and has infected 19 million Americans so far. It's influenza | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
The coronavirus is prompting Americans to buy up surgical masks. Another virus, the flu, has killed more than 10,000 this season alone. Because the flu is a constant in Americans' lives, the familiarity makes it more dangerous to underestimate.

Via Ed Rybicki
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Coronavirus: Are anti-vaxxers ready to believe in vaccines again?

Coronavirus: Are anti-vaxxers ready to believe in vaccines again? | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
With coronavirus on the rampage, perhaps the people who don’t believe in vaccinations will rethink their irresponsible position.

Via Ed Rybicki
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The physician whose 1964 vaccine beat back rubella is working to defeat the new coronavirus

The physician whose 1964 vaccine beat back rubella is working to defeat the new coronavirus | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
Stanley Plotkin is consulting for multiple companies and says more than one vaccine may be needed in this new pandemic
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RT-qPCR DETECTION OF SARS-CoV-2 RNA FROM PATIENT NASOPHARYNGEAL SWAB USING QIAGEN RNEASY KITS OR DIRECTLY VIA OMISSION OF AN RNA EXTRACTION STEP | bioRxiv

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Coronavirus fatality rate estimated by Imperial College London scientists

Coronavirus fatality rate estimated by Imperial College London scientists | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
CORONAVIRUS DEATHS - Imperial researchers have released estimates on the proportion of people who may die from the disease.

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With viruses like flu and coronavirus, pneumonia often delivers the fatal blow

With viruses like flu and coronavirus, pneumonia often delivers the fatal blow | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it

There may be an important difference in the kind of pneumonia that #flu and #COVID-19 patients get that could make #coronavirus pneumonia harder to treat.


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Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope | Journal of Virology

ABSTRACT Porcine circovirus type 2 (PCV2) is an important pathogen in swine herds, and its infection in pigs has caused severe economic losses to the pig industry worldwide. The capsid protein of PCV2 is the only structural protein that is associated with PCV2 infection and immunity. Here, we report a neutralizing monoclonal antibody (mAb), 3A5, which binds to intact PCV2 virions of PCV2a, PCV2b and PCV2d genotypes. The mAb 3A5 neutralized PCV2 by blocking viral attachment to PK15 cells. To further explore the neutralization mechanism, we resolved the structure of the PCV2 virion in complex with mAb 3A5 Fab fragments by using cryo-electron microscopy (cryo-EM) single particle analysis. The binding sites were located at the topmost edges around fivefold icosahedral symmetry axes, with each footprint covering amino acids from two adjacent capsid proteins. Most of the epitope residues (15/18) are conserved among 2,273 PCV2 strains. Mutations of some amino acids within the epitope had a significant effect on the neutralizing activity of mAb 3A5. This study reveals the molecular and structural basis of this PCV2-neutralizing antibody and provides new and important information for vaccine design and therapeutic antibody development against PCV2 infections. IMPORTANCE Porcine circovirus type 2 (PCV2) is associated with several clinical manifestations collectively known as porcine circovirus-associated diseases (PCVADs). Neutralizing antibodies play a crucial role in the prevention of PCVADs. We have previously demonstrated that a monoclonal antibody (mAb), 3A5, neutralizes the PCV2a, PCV2b and PCV2d genotypes with different degrees of efficiencies, but the underlying mechanism remains elusive. Here, we report the neutralization mechanism of this mAb and the structure of the PCV2 virion in complex with the mAb 3A5 Fabs, showing a binding mode in which one Fab interacted with more than two loops from two adjacent capsid proteins. This binding mode has not been observed before for PCV2 neutralizing antibodies. Our work provides new and important information for vaccine design and therapeutic antibody development against PCV2 infections.
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China closes in on vaccine for deadly pig virus

China closes in on vaccine for deadly pig virus | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
Bu says that extensive laboratory experiments have demonstrated the low risk of reversion for the seven-gene-deleted variant. But before launching a vaccine, his team will run a clinical trial, which will involve some 10,000–20,000 pigs.
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How to Conquer Coronavirus: Top 35 Treatments in Development

How to Conquer Coronavirus: Top 35 Treatments in Development | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
A new survey by Genetic Engineering & Biotechnology News (GEN) reveals 35 active drug development programs in North America, Europe and China.
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New treatment ‘made from sugar’ could help fight viral outbreaks

New treatment ‘made from sugar’ could help fight viral outbreaks | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
The team has “successfully engineered a new molecule, which is a modified sugar that shows broad-spectrum antiviral properties.” - News - PharmaTimes...
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Anatomy of a killer - Understanding SARS-CoV-2 and the drugs that might lessen its power

Anatomy of a killer - Understanding SARS-CoV-2 and the drugs that might lessen its power | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
Modest improvements in treatment could make a big difference...

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Why the Covid-19 coronavirus is worse than the flu, in one chart

Why the Covid-19 coronavirus is worse than the flu, in one chart | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
It’s more contagious, more deadly (particularly for older people), and it has a greater potential to overwhelm our health care system.

Via Ed Rybicki
Ed Rybicki's curator insight, March 19, 5:13 AM
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What We Know So Far About SARS-CoV-2

What We Know So Far About SARS-CoV-2 | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
We’ve known about SARS-CoV-2 for only three months, but scientists can make some educated guesses about where it came from and why it’s behaving in such an extreme way.

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Why the push for a quick coronavirus vaccine could backfire

Why the push for a quick coronavirus vaccine could backfire | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
“There’s a lot of hope for a [coronavirus] vaccine but there obviously has to be a lot of caution,” said a Vanderbilt University pediatrician....

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WHO launches global megatrial of the four most promising coronavirus treatments

WHO launches global megatrial of the four most promising coronavirus treatments | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
Simple design aims to let even overwhelmed physicians and hospitals participate
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Interactive map tracks the coronavirus outbreak

Interactive map tracks the coronavirus outbreak | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
A new interactive map for the novel coronavirus outbreak shows the numbers of cases, recoveries, and deaths, as well as trends over time.

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COVID-19 Vaccine Test Begins With U.S. Volunteer

COVID-19 Vaccine Test Begins With U.S. Volunteer | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
U.S. researchers gave the first shot to the first person in a test of an experimental coronavirus vaccine Monday.

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Virus literacy for beginners: Influenza and Covid-19

Virus literacy for beginners: Influenza and Covid-19 | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
In the 1980s and early 1990s organisations such as Gay Men’s Health Crisis, ACT-UP and later the Treatment Action Campaign in South Africa pioneered ‘treatment literacy’ as one strategy to empower vulnerable communities in the response to HIV/AIDS. The premise of treatment literacy is that people are better equipped to respond to disease threats if they understand the science of the disease they are confronting. The same will be true of Covid-19.

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Taiwan sets example for world on how to fight coronavirus

Taiwan sets example for world on how to fight coronavirus | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it

Taiwan has only had 49 confirmed cases and one death, an astonishingly low number considering its proximity to China and frequency of flights between the two countries.

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The JavaScript Beginner's Handbook (2020 Edition)

The JavaScript Beginner's Handbook (2020 Edition) | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it

JavaScript is one of the most popular programming languages in the world.

I believe it's a great choice for your first programming language ever.

We mainly use JavaScript to create

* websites
* web applications
* server-side applications using Node.js

but JavaScript is not limited to these things, and it can also be used to

* create mobile applications using tools like React Native
* create programs for microcontrollers and the internet of things
* create smartwatch applications

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Bioinformatics and other bits - Explore the SARS-CoV-2 spike protein sequences using Python tools

Bioinformatics and other bits - Explore the SARS-CoV-2 spike protein sequences using Python tools | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
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Read the Book | Bioinformatics Algorithms

Read the Book | Bioinformatics Algorithms | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
Read our free best-selling textbook, Bioinformatics Algorithms. Learn from our lecture videos, and explore our popular online courses.
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Novel coronavirus 'is probably with us beyond this season, beyond this year,' CDC director says

Novel coronavirus 'is probably with us beyond this season, beyond this year,' CDC director says | Viruses, Immunology & Bioinformatics from 4Virology.net at UVic | Scoop.it
As an outbreak of a novel coronavirus has swept through Hubei province, China, the US Centers for Disease Control and Prevention has been preparing for its worst case scenario -- a widespread outbreak of illnesses in the United States.
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