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Three-dimensional light-sensitive retinal tissue grown in lab

Three-dimensional light-sensitive retinal tissue grown in lab | Stem cell news | Scoop.it
Researchers at John Hopkins have constructed a functioning segment of a human retina out of stem cells that is able to respond to light.
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Insulin independence achieved with novel stem cell therapy - Clinical Endocrinology News Digital Network

Insulin independence achieved with novel stem cell therapy Clinical Endocrinology News Digital Network "Exogenous insulin therapy does not always achieve metabolic control in type 1 diabetes, nor prevent the occurrence of complications or halt...
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Scientists Report First Success in Cloning Human Stem Cells | TIME.com

Scientists Report First Success in Cloning Human Stem Cells | TIME.com | Stem cell news | Scoop.it
It’s been 17 years since Dolly the sheep was cloned from a mammary cell. And now scientists applied the same technique to make the first embryonic-stem-cell lines from human skin cells.
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CIRM Stem Cell Research Updates: Perfecting the use of stem cells ...

CIRM Stem Cell Research Updates: Perfecting the use of stem cells ... | Stem cell news | Scoop.it
The innate tendency of stem cells to seek out inflammation—combined with the fact that our bodies see tumors as inflammation—has led many teams to try to harness stem cells as delivery vehicles for cancer therapies.
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Genetic Switching Element Turns Stem Cells into Differentiated Cells - Drug Discovery & Development

Genetic Switching Element Turns Stem Cells into Differentiated Cells - Drug Discovery & Development | Stem cell news | Scoop.it
Drug Discovery & Development Genetic Switching Element Turns Stem Cells into Differentiated Cells Drug Discovery & Development Stem cells (Photo: Nissim Benvenisty, Wikipedia.com) Slight modifications in their genome sequences play a crucial role...
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Humanized pig organs to revolutionize transplantation | KurzweilAI

Humanized pig organs to revolutionize transplantation | KurzweilAI | Stem cell news | Scoop.it
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Genome pioneer J. Craig Venter’s Synthetic Genomics Inc. (SGI) is teaming up with United Therapeutics Corporation subsidiary Lung Biotechnology Inc. to use synthetic genomic advances to develop humanized pig lungs.

The collaboration will focus on creating organs that are safe and effective for use in human patients in need of transplantation, with an initial focus on lung diseases — addressing specifically the urgent need for transplant organs for people with end-stage lung disease.

SGI  plans to use its unique DNA design, DNA synthesis, genome editing, and genome-modification tools to develop engineered primary pig cells with modified genomes. This will involve modifying a substantial number of genes at an unprecedented scale and efficiency, the company says.

400,000 people die annually from lung disease

United Therapeutics will leverage its xenotransplantation (between-species) expertise to implant these engineered cells, generating pig embryos that are born with humanized lungs.

“We believe that our proprietary synthetic genomic tools and technologies, coupled with United Therapeutics’ knowledge and advances in regenerative medicine technologies and treatment of lung diseases, should enable us to develop humanized pig organs for safe and effective transplant into humans,” said said J. Craig Venter, Ph.D., Founder and CEO, SGI. “We believe this is one of the most exciting and important programs ever undertaken in modern medical science.”


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Engineers grow functional human cartilage in lab

Engineers grow functional human cartilage in lab | Stem cell news | Scoop.it
Engineers have successfully grown -- for the first time -- fully functional human cartilage in vitro from human stem cells derived from bone marrow tissue.
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Men's Skin Cells Turned Into Sperm Precursors

Men's Skin Cells Turned Into Sperm Precursors | Stem cell news | Scoop.it
Skin cells from infertile men can be turned into stem cells that then form precursors to sperm when implanted into the testes of mice, according to a new study. (Doctors have made a big breakthrough for infertile men.
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Cell Sciences Inc. – Google+ - Researchers at the University of Washington have restored…

Cell Sciences Inc. – Google+ - Researchers at the University of Washington have restored… | Stem cell news | Scoop.it
Researchers at the University of Washington have restored damaged heart muscle of monkeys using heart cells created from human embryonic stem cells.
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Stem cell therapy regenerates heart muscle damaged from heart attacks in primates

Stem cell therapy regenerates heart muscle damaged from heart attacks in primates | Stem cell news | Scoop.it
Heart cells created from human embryonic stem cells successfully restored damaged heart muscles in monkeys, researchers report.
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Human Somatic Cell Nuclear Transfer Using Adult Cells: Cell Stem Cell

Human Somatic Cell Nuclear Transfer Using Adult Cells: Cell Stem Cell | Stem cell news | Scoop.it
Human Somatic Cell Nuclear Transfer Using Adult Cells: Cell Stem Cell http://t.co/yM6lZNVfIv
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A protein required for integrity of induced pluripotent stem cells

A protein required for integrity of induced pluripotent stem cells | Stem cell news | Scoop.it
Cell reprogramming converts specialised cells such as nerve cells or skin cells towards an embryonic stem cell state. This reversal in the evolutionary development of cells also requires a reversal in the biology of telomeres, ...
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Scientists Clone Embryonic Stem Cells From Adult Skin - American Live Wire

Scientists Clone Embryonic Stem Cells From Adult Skin - American Live Wire | Stem cell news | Scoop.it
Headlines & Global News Scientists Clone Embryonic Stem Cells From Adult Skin American Live Wire For the first time, United States researchers have cloned embryonic stem cells from their original adult cells, a scientific breakthrough on the road...
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Neuron Tells Stem Cells to Grow New Neurons

Neuron Tells Stem Cells to Grow New Neurons | Stem cell news | Scoop.it
Researchers discover a new type of neuron in the adult brain which is capable of telling stem cells to grow more neurons.
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Laser light triggers stem cells to regrow teeth - Boston Globe

Laser light triggers stem cells to regrow teeth - Boston Globe | Stem cell news | Scoop.it
Boston Globe
Laser light triggers stem cells to regrow teeth
Boston Globe
With a simple, low-power laser, Harvard University scientists have triggered naturally-occurring dental stem cells to regrow teeth in rats.
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Functional Nerve Cells from Skin Cells

Functional Nerve Cells from Skin Cells | Stem cell news | Scoop.it
Cambridge, UK (Scicasts) — A new method of generating mature nerve cells from skin cells could greatly enhance understanding of neurodegenerative diseases, and could accelerate the development of new drugs and stem cell-based regenerative medicine.
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Genetic tracking identifies cancer stem cells in patients | University of Oxford

Genetic tracking identifies cancer stem cells in patients | University of Oxford | Stem cell news | Scoop.it
The gene mutations driving cancer have been tracked for the first time in patients back to a distinct set of cells at the root of cancer – cancer stem cells.
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Skin layer grown from human stem cells could replace animals in drug and cosmetics testing | KurzweilAI

Skin layer grown from human stem cells could replace animals in drug and cosmetics testing | KurzweilAI | Stem cell news | Scoop.it

An international team led by King’s College London and the San Francisco Veteran Affairs Medical Center (SFVAMC) has developed the first lab-grown epidermis (the outermost skin layer) with a functional permeability barrier akin to real skin.

The new epidermis, grown from human pluripotent stem cells, offers a cost-effective alternative lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common skin disorders.

The epidermis, the outermost layer of human skin, forms a protective interface between the body and its external environment, preventing water from escaping and microbes and toxins from entering.

Tissue engineers have been unable to grow epidermis with the functional barrier needed for drug testing or produce an in vitro (lab) model for large-scale drug screening. That’s because the number of cells that can be grown from a single skin biopsy sample has been limited.

The new study, published in the journal Stem Cell Reports (open access), describes the use of human induced pluripotent stem cells (iPSC) (stem cells that can develop into different types of body cells) to produce an unlimited supply of pure keratinocytes (the predominant cell type in the outermost layer of skin). These new keratinocytes closely match keratinocytes generated from other stem-cell types: human embryonic stem cells (hESC) and primary keratinocytes from skin biopsies.


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Mesenchymal Stem Cells Ameliorate Cerebellar Pathology in a Mouse Model of Spinocerebellar Ataxia Type 1 - Springer

Mesenchymal Stem Cells Ameliorate Cerebellar Pathology in a Mouse Model of Spinocerebellar Ataxia Type 1 - Springer | Stem cell news | Scoop.it
Mesenchymal Stem Cells Ameliorate Cerebellar Pathology in a Mouse Model of Spinocerebellar Ataxia Type 1 http://t.co/ytSZ3KPltL
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New non-coding RNAs keep stem cells stemmy : Free Association

New non-coding RNAs keep stem cells stemmy : Free Association | Stem cell news | Scoop.it
Stem cells are increasingly being used to develop new disease treatments and to understand the basic biology of a number of diseases. However, one of the questions that still needs to be answered regarding stem cells is ...
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Human Fat: A Trojan Horse to Fight Brain Cancer?

Human Fat: A Trojan Horse to Fight Brain Cancer? | Stem cell news | Scoop.it
Researchers have successfully used stem cells derived from human body fat to deliver biological treatments directly to the brains of mice with glioblastomas, the most common and aggressive form of brain tumor, significantly extending their lives.
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First Patient-Specific Human Embryonic Stem Cells Created - Columbia University Medical Center

First Patient-Specific Human Embryonic Stem Cells Created - Columbia University Medical Center | Stem cell news | Scoop.it
Scientists at the New York Stem Cell Foundation and CUMC have created the first disease-specific embryonic stem cell line using nuclear transfer technology.
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Stem Cells Regenerate Heart Muscle!

Stem Cells Regenerate Heart Muscle! | Stem cell news | Scoop.it
Injections of human stem cells can replace dead heart tissue in monkeys, spurring the growth of muscle patches 10 times larger than ever before. The technique may one day help treat heart failure in humans.
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Stem Cells Made From Cloning Diabetic Woman - NBC News

Stem Cells Made From Cloning Diabetic Woman - NBC News | Stem cell news | Scoop.it
Scientists have used cloning technology to make stem cells from a woman with Type 1 diabetes that are genetically matched to her and to her disease.They hope...
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Light-activated neurons from stem cells restore function to paralysed muscles

Light-activated neurons from stem cells restore function to paralysed muscles | Stem cell news | Scoop.it
Light-activated neurons from stem cells restore function to paralysed muscles http://t.co/wlCibfWlAp
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