Plant and Seed Biology
30.8K views | +5 today
Follow
Plant and Seed Biology
Your new post is loading...
Your new post is loading...
Rescooped by Loïc Lepiniec from Genetic Engineering - GEG Tech top picks
Scoop.it!

Applying CRISPR/Cas for genome engineering in plants: the best is yet to come

Applying CRISPR/Cas for genome engineering in plants: the best is yet to come | Plant and Seed Biology | Scoop.it

Via BigField GEG Tech
BigField GEG Tech's curator insight, December 5, 2016 9:54 AM

Less than 5 years ago the CRISPR/Cas nuclease was first introduced into eukaryotes, shortly becoming the most efficient and widely used tool for genome engineering. For plants, efforts were centred on obtaining heritable changes in most transformable crop species by inducing mutations into open reading frames of interest, via non-homologous end joining.

Rescooped by Loïc Lepiniec from Genetic Engineering - GEG Tech top picks
Scoop.it!

Genetic screens: CombiGEM-CRISPR: a creative combination - Nature Reviews Genetics 

Genetic screens: CombiGEM-CRISPR: a creative combination - Nature Reviews Genetics  | Plant and Seed Biology | Scoop.it

Via BigField GEG Tech
Loïc Lepiniecs insight:

Researchers have generated a platform that uses combinatorial genetics en masse (CombiGEM) and the CRISPR–Cas9 system for the rapid assembly of barcoded combinatorial genetic libraries that can be tracked with high-throughput sequencing.

BigField GEG Tech's curator insight, March 2, 2016 7:55 AM

Researchers have generated a platform that uses combinatorial genetics en masse (CombiGEM) and the CRISPR–Cas9 system for the rapid assembly of barcoded combinatorial genetic libraries that can be tracked with high-throughput sequencing.

Rescooped by Loïc Lepiniec from Genetic Engineering - GEG Tech top picks
Scoop.it!

Second Chinese team reports gene editing in human embryos

Second Chinese team reports gene editing in human embryos | Plant and Seed Biology | Scoop.it
Study used CRISPR technology to introduce HIV-resistance mutation into embryos.

Via BigField GEG Tech
BigField GEG Tech's curator insight, April 12, 2016 9:18 AM

Researchers in China have reported editing the genes of human embryos to try to make them resistant to HIV infection. Their paper which used CRISPR-editing tools in non-viable embryos that were destroyed after three days is only the second published claim of gene editing in human embryos.