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London man becomes only second person to be 'cured' of HIV as scientists hail breakthrough

London man becomes only second person to be 'cured' of HIV as scientists hail breakthrough | MRC research in the news | Scoop.it
A British man may be the second person to be cured of HIV as doctors said he was in ‘sustained remission’ after being given stem cells from a donor with genetic resistance to the disease.
MRC press's insight:
The research was partly funded by Wellcome, the Medical Research Council, the Foundation for AIDS Research, and National Institute for Health Research (NIHR) Biomedical Research Centres at University College London Hospitals, Oxford and Cambridge.
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Scientist brings cure for brain cancer to an embryonic stage | Scotland | The Times

Scientist brings cure for brain cancer to an embryonic stage | Scotland | The Times | MRC research in the news | Scoop.it

When he was a 19-year-old biochemistry student on an internship in Memphis, Tennessee, Steven Pollard would catch a lift on a bus taking child cancer patients to hospital.

MRC press's insight:
A brain tumour strikes fast with devastating effect and has a low survival rate, but the approach of Professor Steven Pollard and his team at the MRC Centre for Regenerative Medicine at the Royal Infirmary, Edinburgh, could transform the prospects for brain tumour patients.
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Tens of thousands of UK children have PTSD due to bullying and violence, Lancet study finds

Tens of thousands of UK children have PTSD due to bullying and violence, Lancet study finds | MRC research in the news | Scoop.it
Nearly 100,000 children are suffering from post traumatic stress disorder (PTSD) because of severe bullying and violence, researchers have warned.
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The research was funded by the Medical Research Council, a UK Government funding agency.
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Scottish scientists work could prevent age-related ailments - The National

Scottish scientists work could prevent age-related ailments - The National | MRC research in the news | Scoop.it
MANIPULATING tiny parts of cells could help prevent the damaging effects linked to ageing, Scottish scientists have revealed.
MRC press's insight:
Programme manager for genetics, epigenetics and genomics at the MRC, Dr Lindsay Wilson, added: “Senescence is an essential self-defence mechanism but at times, can also be harmful. Professor Bickmore’s work suggests ways in which scientists of the future might target these harmful effects, for example in age-related diseases.”
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Study links heavily processed foods to risk of earlier death | Society | The Guardian

Study links heavily processed foods to risk of earlier death | Society | The Guardian | MRC research in the news | Scoop.it
French research involved more than 44,000 people over a period of seven years
MRC press's insight:
“The case against highly processed foods is mounting up, with this study adding importantly to a growing body of evidence on the health harms of ultra-processed foods,” said Prof Nita Forouhi, of the MRC Epidemiology Unit at the University of Cambridge. She said more evidence was needed, “yet we would ignore these findings at public health’s peril”.
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Students paid up to £3,500 to catch potentially deadly diseases for science 

Students paid up to £3,500 to catch potentially deadly diseases for science  | MRC research in the news | Scoop.it
Cash strapped university students are being paid as much as £3,500 to be infected with dangerous tropical diseases including typhoid, malaria and pneumonia.
MRC press's insight:
The Medical Research Council has established a new programme, Hic-Vac, which provides £100,000 grants to support scientists setting up challenge trials. The project is also creating a global network of researchers to share advice and insights about how to run a successful study.
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'Fake news and ageism' keeping statins from older people | Society | The Guardian

'Fake news and ageism' keeping statins from older people | Society | The Guardian | MRC research in the news | Scoop.it
Offering statins to all over-75s could prevent 8,000 deaths from heart failure and stroke, researchers say
MRC press's insight:
There are 5.5 million people aged over 75 in the UK, of whom about 1.5 million take a statin. If the rest did so too, about 8,000 additional deaths from cardiovascular events could be prevented, said Prof Colin Baigent, director of the Medical Research Council population health research unit at Oxford University.
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The trouble with fake meat | Food | The Guardian

The trouble with fake meat | Food | The Guardian | MRC research in the news | Scoop.it
From beetroot burgers to hoisin ‘duck’, imitation meats are everywhere. But are these substitutes any healthier for us to eat?
MRC press's insight:
I consult Dr Fumiaki Imamura, an epidemiologist at the MRC Epidemiology Unit in Cambridge. He notes that there is “no evidence” from large-scale studies that specifically looks at such products. He directed me to a Harvard study from 2016 which suggested that people who ate more plant protein and less animal protein had lower overall risk of death, but the plant protein in the study was mostly beans, pulses and nuts rather than Quorn “bacon” strips.
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Thinness and obesity: it's in the genes | Society | The Guardian

Thinness and obesity: it's in the genes | Society | The Guardian | MRC research in the news | Scoop.it

Some people seem to be able to eat all the burgers and chips they like and and stay the same size, shape and weight all their life. Researchers at the University of Cambridge have discovered that they have a genetic advantage over their overweight friends who live and eat in the same way that they do.

MRC press's insight:
Prof Sadaf Farooqi at the Wellcome-MRC Institute of Metabolic Science recruited 2,000 healthy but thin individuals for a study called Stilts (Study Into Lean and Thin Subjects) to find out whether there was something particular about their lives or their genes.
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Brilliance in the genes: inside Britain's 'Nobel prize factory'

Brilliance in the genes: inside Britain's 'Nobel prize factory' | MRC research in the news | Scoop.it
FT science editor Clive Cookson on the latest R&D at the UK Medical Research Council's Laboratory of Molecular Biology. The maverick institution has produced 16 Nobel laureates in the past 60 years.
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During a visit to the MRC LMB, journalist Clive Cookson interviews key scientists.
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Bart De Strooper: ‘Bright young scientists won’t come to join us in UK’ | Society | The Guardian

Bart De Strooper: ‘Bright young scientists won’t come to join us in UK’ | Society | The Guardian | MRC research in the news | Scoop.it

Bart De Strooper is clear about his decision to accept the post of running Britain’s massive pioneering research project on dementia. “I would have not gone for it had I known what I know now,” the 59-year-old Belgian biologist told the Observer last week.

MRC press's insight:
The cause of his dismay is simple: Brexit has blighted the nation and distorted its attitude to international science, said De Strooper. As a result, his UK Dementia Research Institute, set up in 2016 at a cost of £250m with the aim of turning the UK into a world leader in dementia research, now faces serious funding and recruitment problems.
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‘Stealth disease’ written off as old age may be behind thousands of cancers and joint problems, study shows

‘Stealth disease’ written off as old age may be behind thousands of cancers and joint problems, study shows | MRC research in the news | Scoop.it

A “stealth disease” which causes iron to build up to toxic levels may be responsible for thousands of cancers and disabling joint problems written off as part of ageing, a British study has found.

MRC press's insight:
Professor Melzer’s team studied 2,890 patients enrolled the UK Biobank scheme who carry mutations in the HFE C282Y gene that causes the condition.
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Beyond ‘superbabies’: how Crispr is revolutionising medicine

Beyond ‘superbabies’: how Crispr is revolutionising medicine | MRC research in the news | Scoop.it

The tail-end of last year brought news that a Chinese scientist had apparently created the world’s first genome-edited babies. It left fellow scientists, and the rest of the world, horrified that such a momentous leap had occurred in secret, with its potential for unintended consequences.

MRC press's insight:
“Many scientists consider genome editing to have great potential for dealing with inherited genetic disorders,” says Professor Robin Lovell-Badge, a developmental biologist and geneticist at the Francis Crick Institute in London. The Francis Crick Institute receives its core funding from the MRC, Cancer Research UK and Wellcome.
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How we are unwittingly drawn to those with a similar life expectancy | Daily

How we are unwittingly drawn to those with a similar life expectancy | Daily | MRC research in the news | Scoop.it
Experts at the University of Edinburgh say the findings help explain why long-term couples often suffer from the same ailments in later years and can have similar life spans.
MRC press's insight:
Professor Albert Tenesa, of the MRC Human Genetics Unit, said: "Our study suggests that humans tend to select partners for behavioural or physical traits that are genetically related to disease and longevity."
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Tangerine Dream: how German electronica is helping genetic science at The Francis Crick Institute 

Tangerine Dream: how German electronica is helping genetic science at The Francis Crick Institute  | MRC research in the news | Scoop.it

German electronica, eyelashes stuck on cocktail sticks and 1.5 million fruit flies are the secret weapons of one of Britain’s largest scientific centre, it has emerged.

MRC press's insight:
The Francis Crick Institute in London is at the cutting edge of research into cancer, Alzheimer’s and genetic engineering. Now ‘The Crick’ is flinging open its doors to disclose the unusual goings-on of its technicians for a new exhibition into the unseen side of science.
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Takeda ties up with Dundee uni to combat Alzheimer’s - The Scotsman

Takeda ties up with Dundee uni to combat Alzheimer’s - The Scotsman | MRC research in the news | Scoop.it
A drug discovery group at the University of Dundee is teaming up with a Japanese pharmaceutical giant to develop potential treatments for diseases including Alzheimer’s.
MRC press's insight:
The University of Dundee’s Drug Discovery Unit, in conjunction with Will McEwan from the University of Cambridge and Leo James at the Medical Research Council Laboratory of Molecular Biology, has identified drug-like molecules that prevent the “seeded misfolding” of tau.
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Early stages of lung cancer could be detected with a simple blood test | Daily

Early stages of lung cancer could be detected with a simple blood test | Daily | MRC research in the news | Scoop.it
Scientists at the MRC's Toxicology Unit at the University of Cambridge analysed the blood tests of mice with a genetic mutation known as KRAS, which replicates the early signs of lung cancer.
MRC press's insight:
Dr Mariana Delfino-Machin, programme manager for cancer at the Medical Research Council (MRC), which funded the study, said: 'This is a really promising piece of early-stage research. 'Lung cancer is incredibly difficult to diagnose at the stage where it can be successfully treated, leading to a poor rate of survival.
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Michael McIntyre’s jokes used by scientists to help ward off flu - Mirror Online

Michael McIntyre’s jokes used by scientists to help ward off flu - Mirror Online | MRC research in the news | Scoop.it

Scientists are using Michael McIntyre's jokes as part of a £315,000 clinical trial
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The trial, which is due to start later this year, is funded by the Medical Research Council.
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Male volunteers wanted to trial groundbreaking contraceptive gel

Male volunteers wanted to trial groundbreaking contraceptive gel | MRC research in the news | Scoop.it
A contraceptive treatment for men is being put to the test and researchers are seeking couples in Edinburgh and Manchester to take part in a groundbreaking study.
MRC press's insight:
Professor Richard Anderson, of the University of Edinburgh's MRC Centre for Reproductive Health, said: "Previous trials have shown that hormonal contraception for men can be safe and effective."
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Looking after your heart helps avoid Alzheimer's | Daily

Looking after your heart helps avoid Alzheimer's | Daily | MRC research in the news | Scoop.it
They are among our most devastating killers: heart disease and dementia. And now, new evidence from experts suggests these two diseases, which blight the lives of millions of Britons, are linked.
MRC press's insight:
Funded by the BHF, Alzheimer's Research UK and the Medical Research Council, Prof Schott and his team are in the final stages of a major study tracking hundreds of British men and women born in the same week in 1946 who had blood pressure monitored from their 30s.
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Downing a bottle of wine a week costs, gulp, £2,400 a year in lost quality of life | News | The Sunday Times

Downing a bottle of wine a week costs, gulp, £2,400 a year in lost quality of life | News | The Sunday Times | MRC research in the news | Scoop.it

While alcoholic drinks may briefly make people feel happy, researchers found the long-term damage to their health, mental ability and relationships far outweighed the benefits.

MRC press's insight:
The research, funded by the Medical Research Council, involved analysis of the health, wealth and lifestyle of 141,000 British drinkers aged 37-73. The aim was to compare alcohol’s benefits, such as making people feel happy or sociable, with the higher risk of depression, insomnia and cognitive decline.
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UK funding on neglected diseases almost doubles in a year, as global health spending hits record high

UK funding on neglected diseases almost doubles in a year, as global health spending hits record high | MRC research in the news | Scoop.it

UK funding for global health, particularly malaria and tuberculosis, has skyrocketed in recent years, according to a report published on Wednesday.

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The Medical Research Council and Department for Health and Social Care also committed £32 and £31 million respectively to neglected diseases.
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Gene clue may help predict breast cancer relapse | Scotland | The Times

Gene clue may help predict breast cancer relapse | Scotland | The Times | MRC research in the news | Scoop.it

Scientists have identified genetic changes that may predict the likelihood of breast cancer relapse in women undergoing hormone therapy.

MRC press's insight:
Andy Sims, of the MRC Institute of Genetics and Molecular Medicine, said: “This is the first time we have been able to investigate genetic changes in individual patients’ tumours over time. We hope the findings will help to develop new tests that predict which women on hormone therapy are likely to relapse so that they can be offered alternative treatments.”
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Social jetlag – are late nights and chaotic sleep patterns making you ill? | Life and style | The Guardian

Social jetlag – are late nights and chaotic sleep patterns making you ill? | Life and style | The Guardian | MRC research in the news | Scoop.it
Waking later at weekends can have the same effect as jetlag – and lead to weight gain, reduced mental performance and chronic illness. But there is a solution.
MRC press's insight:
“We found that just one hour of social jetlag led to the accumulation of about two additional kilograms of fat mass, on average, by the age of 39,” says Michael Parsons, a circadian biology researcher at the Medical Research Council’s Harwell Institute in Oxfordshire, who led the study.
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Drug used to treat stroke may also prevent Alzheimer's | Daily

Drug used to treat stroke may also prevent Alzheimer's | Daily | MRC research in the news | Scoop.it

An experimental drug used to treat stroke may also prevent Alzheimer's, research suggests.

MRC press's insight:
Professor Tara Spires-Jones, of the UK Dementia Research Institute, added: 'Dr Zlokovic and his team published a very encouraging paper showing that a drug called 3K3A-APC prevents Alzheimer's-like symptoms in a mouse model of disease.
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