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IBB Researchers Edit Book on GPCR Screening Assays

IBB Researchers Edit Book on GPCR Screening Assays | iBB | Scoop.it

The book G Protein Coupled Receptor Screening Assays: Methods and Protocols, edited by BERG-IBB researchers Sofia Martins and Miguel Prazeres, has just been published. The book reaches out to everyone involved in the discovery of GPCR-active drugs, and provides a transversal overview of the different levels of GPCR signaling addressable in the different screening strategies and presents practical examples of how current assay technologies are contributing to new paradigms in GPCR drug research. The book stems from the posto-doctoral work of Sofia Martins and features contributions from renowed specialists in the area. Click on title to learn more.

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ERASMUS MUNDUS EuSysBio Winter School in Systems Biology to Take Place at IST

ERASMUS MUNDUS EuSysBio Winter School in Systems Biology to Take Place at IST | iBB | Scoop.it

"The fifth edition of the Winter School in Systems Biology will be organized at IST, from the 5th to the 9th of January 2015, within the scope of the ERASMUS MUNDUS EuSysBio Master programme in Systems Biology. This programme is offered by a consortium that includes IST and two other universities of the CLUSTER: KTH in Stockholm, Sweden, and Aalto University in Finland. Several sessions of this Winter School are open to the public. These conferences will focus on various approaches and scientific fields that contribute to Systems Biology, applied to diverse biological systems, from microorganisms of biotechnological and clinical interest to cancer cells, namely, Systems Metabolic Engineering, Functional Genomics and Glicomics, Comparative Genomics and Phylogeny."

 

Program: https://fenix.tecnico.ulisboa.pt/downloadFile/1692629431484801/DetailedProgram_WS2015.pdf

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Career Trends: Exploring Careers Beyond the Bench

Career Trends: Exploring Careers Beyond the Bench | iBB | Scoop.it

"If you are considering making the move from the lab, you are not alone. This transition is taking place at all career levels, spurred by different motivations. Whatever the reason, many have successfully taken this road, and so can you. Click on title to learn more."

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Bill & Melinda Gates Foundation: New Interventions for Global Health

Bill & Melinda Gates Foundation: New Interventions for Global Health | iBB | Scoop.it

"The Bill & Melinda Gates Foundation is launching a new Grand Challenge: New Interventions for Global Health. This challenge focuses on innovative concepts for vaccines, therapeutics, and diagnostics with the potential to be translated into safe, effective, affordable, and widely utilized interventions to protect against the acquisition, progression, or transmission of infectious diseases, or to provide a cure for infectious diseases, in resource‐limited settings."

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Predatory Publishing: Beall´s List

Predatory Publishing: Beall´s List | iBB | Scoop.it

"Potential, possible, or probable predatory scholarly open-access publishers: This is a list of questionable, scholarly open-access publishers. We recommend that scholars read the available reviews, assessments and descriptions provided here, and then decide for themselves whether they want to submit articles, serve as editors or on editorial boards.  The criteria for determining predatory publishers are here."

Miguel Prazeres's insight:

"In a time when everyday we are invited to publish research in Open Access journals, checking Beall's list is imperative"

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ReMed - Advanced Course on Regenerative Medicine

ReMed - Advanced Course on Regenerative Medicine | iBB | Scoop.it

"The 4th Advanced Course on Regenerative Medicine will take place at the 12th of December 2014. It is organized by the Centre for Rapid and Sustainable Product Development (CDRSP) and its aim is to illustrate the state-of-the-art regarding the principles and methodologies associated with Regenerative Medicine."

 

Miguel Prazeres's insight:

Cláudia Lobato da Silva from BERG-iBB will deliver an oral presentation entitled "Stem Cell Bioengineering Strategies in Regenerative Medicine".

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Post-doctoral Researcher Nuno Lourenço Joins Hovione

Post-doctoral Researcher Nuno Lourenço Joins Hovione | iBB | Scoop.it

After six years as a post-doctoral researcher at BERG-iBB, Nuno Miguel Torres Lourenço is facing a new challenge starting this November. Nuno will be joining Hovione, a Portuguese Pharmaceutical Company dedicated to bringing new and off-patent drugs to market as a Process Chemist. At iBB, his research was centered at the interface of organic chemistry and biotechnology. During the past years Nuno explored topics such as the enzymatic resolution of racemic mixtures, biocatalyzed asymmetric synthesis of fine chemicals, preparation of new biocompatible templates (Ion Jelly®) and the use of alternative reaction medium such as ionic liquids and emulsions. We wish Nuno the best of luck for his professional career and look forward to collaborating with him in the near future. 

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Talk on Plasmon Resonances in Single Metal Nanoparticles by Dr. Peter Zijlstra

Talk on Plasmon Resonances in Single Metal Nanoparticles by Dr. Peter Zijlstra | iBB | Scoop.it

Dr. Peter Zijlstra from the Molecular Biosensing for Medical Diagnostics (MBx) group at TU Eindhoven (The Netherlands) will be given a talk on "Plasmon resonances in single metal nanoparticles and their applications" this Friday, 24/10, at 12h00m, in Anfiteatro Abreu Faro (Complexo Interdisciplinar). The MBx group develops technologies to detect proteins and study protein function with single-molecule resolution in complex macromolecular environments such as blood plasma or living cells and investigates biophysical manipulation and detection methods with emphasis on the use of small particles, in particular magnetic and plasmonic nanoparticles.


Photo: Gold nanoparticles. 

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Suitability of a Yeast-based Assay to Assess Pyrimethanil Toxicity in Surface Runoff from Sprayed Soils

Suitability of a Yeast-based Assay to Assess Pyrimethanil Toxicity in Surface Runoff from Sprayed Soils | iBB | Scoop.it

A joint publication from BSRG-iBB and IMAR & MARE – University of Coimbra in the journal Science of the Total Environment describes evaluation of the suitability of a short-term yeast-based gene expression assay to assess the toxicity of pyrimethanil in runoff samples simulated from soils sprayed with fungicide accidental spill doses. Comparison of toxicity data to the yeast and to aquatic and soil standard species pointed the yeast assay relevant for screening worst-cases of fungicide contamination. This work was performed in the context of Fátima Gil’s PhD in Biotechnology (finished july 2014; supervisors: Cristina A Viegas, Jorge H Leitão).

 

Photo sources: en.wikipedia.org, www.zmescience.com, www.marietta.edu, enfo.agt.bme.hu, www.infojardin.com

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Experimental Access to Springer Protocols

Experimental Access to Springer Protocols | iBB | Scoop.it

"Springer's Protocols is the world's most comprehensive collection of protocols in biomedical and life sciences."

Miguel Prazeres's insight:

All units of IST have free access to the Springer Protocols database (> 36000 protocols) between the 6th October and the 6th December via http://www.springerprotocols.com/

 

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Keep Your Money on Your Wallet

Keep Your Money on Your Wallet | iBB | Scoop.it

Money is usually considered a source of infections. In a study comparing the bacterial numbers and diversity on coins collected in Casablanca and Lisbon, Carla C.C.R. de Carvalho (BERG-iBB, IST) and Maria-José Caramujo (FCUL) showed that coins transported in pockets presented higher number of bacterial isolates than coins transported in wallets, regardless of the gender of the person transporting them. The work, published in FEMS Microbiology Ecology, suggests that temperature and moisture might be key parameters for bacterial survival on metallic coins. The percentage of Staphylococcus strains was, curiously, 44% of the total isolates on both Moroccan Dirham and Euro coins. Click on title to learn more.

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FCT Grants Data Can be Added to ORCID Profiles

FCT Grants Data Can be Added to ORCID Profiles | iBB | Scoop.it

"Grants and other funding awards are an important component of a researcher’s output, so being able to add these to an ORCID record is valuable to researchers. However, manually adding grant data is cumbersome and was proving ineffective in generating high quality data, both in the ORCID and in the national repository. FCT andÜberResearch worked together to solve this challenge, by integrating the data of FCT grants awarded since 2000 into the shared global ÜberResearch grants database. Researchers are now able to add their FCT grants to their ORCID profile, with just a few clicks."

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Integration of Sample Preparation and Analyte Detection in a Microfluidic Chip

Integration of Sample Preparation and Analyte Detection in a Microfluidic Chip | iBB | Scoop.it

A joint publication of researchers from BERG-iBB and INESC-MN in the journal Lab-On-a-Chip describes a new method of integrating a liquid sample preparation step based on aqueous two-phase systems in continuous with an immunoassay. This was performed in microfluidic channels with a depth of 20 µm, four times thinner than the average human hair. The strategy allows simultaneous neutralization of matrix interferents, analyte concentration and detection in a single step, thus having great potential for rapid and sensitive point-of-need applications without the need for complex sample preparation procedures.  The work was performed in the context of Ruben Soares's PhD in Biotechnology (supervisors R Aires Barros, JP Conde). Click on the title to learn more.

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Top Ten Bioindustry Trends for 2015

Top Ten Bioindustry Trends for 2015 | iBB | Scoop.it

"As the biotech industry enters a new year the key trends to watch will be those involving the technologies and markets that are expected to grow quickly during 2015. They will be the important drivers of life science R&D and help move biotech into wholly new areas."

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Catarina Costa Defends PhD Thesis in Biotechnology

Catarina Costa Defends PhD Thesis in Biotechnology | iBB | Scoop.it

Catarina Costa has defended her Ph D thesis in Biotechnology at Instituto Superior Técnico, tuesday the 9th December 2014. During the last years, and under the supervision of Miguel Cacho Teixeira from BSRG-IBB, Catarina unveiled novel mechanisms of resistance to antifungal drugs in pathogenic yeasts. The title of her thesis is “Antifungal drug resistance in the pathogenic yeast Candida glabrata: emphasis on the role of the uncharacterized drug:H+ antiporters”. 

Miguel Prazeres's insight:

Congratulations Catarina!

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FCT Rates IBB as an Excellent R&D Unit

FCT Rates IBB as an Excellent R&D Unit | iBB | Scoop.it

The Institute for Bioengineering and Biosciences (iBB-IST) has received the final classification of Excellent, as a result of the 2013 review of the national R&D institutions organized by the Portuguese Foundation of Science and Technology, securing funding for its 2015-2020 strategic program. In their Final consensus report, the evaluation pannel stated that:

 

 "The visit confirmed that IBB is – by many lengths – the strongest Portuguese research venture in many aspects of modern bio-technology. New, and very promising research units within the field are being formed elsewhere in Portugal, but the impact of IBB will remain strong for many years."

 

Read more here: http://www.fct.pt/apoios/unidades/avaliacoes/2013/index.phtml.en

 

Miguel Prazeres's insight:

Congratulations to all IBB members!

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Portugal's Health Tech Start-ups Face Long Race to Launch

Portugal's Health Tech Start-ups Face Long Race to Launch | iBB | Scoop.it

"When Joao Fonseca took his three-year-old son to the doctor, he was upset that he had to wait a few days for the results of a blood test. As a university researcher in the field of biophysics, he decided to try to turn the problem into a business. That was in 2005. [...]"

Click on photo to learn more.

Miguel Prazeres's insight:

"Portuguese start-ups Biosurfit and Magnomics featured in BBC news"

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FCT - 2014 Call for SR&TD Project Grants

FCT - 2014 Call for SR&TD Project Grants | iBB | Scoop.it

Through this call for scientific research and technological development (SR&TD) project grants, FCT wishes to support innovative ideas in all research domains that may make significant contributions to the advancement of scientific knowledge, and show clear potential for significant international impact, measured in terms of scientific output.

Miguel Prazeres's insight:

O concurso fecha a 29 de Janeiro de 2015!

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JoVE, The Journal of Visualized Experiments

JoVE, The Journal of Visualized Experiments | iBB | Scoop.it

The Journal of Visualized Experiments (JoVE) was established as a new tool in life science publication and communication, with participation of scientists from leading research institutions. JoVE takes advantage of video technology to capture and transmit the multiple facets and intricacies of life science research.

Onur Tuna's curator insight, November 3, 2014 2:36 AM

Değişik bir yaklaşım.

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Lipoplex Dissociation and DNA Endosome Escape

Lipoplex Dissociation and DNA Endosome Escape | iBB | Scoop.it

The success of gene delivery through liposomes depends on the effectiveness of endosomal escape and nucleic acid release from the chosen vectors. Performing a simultaneous quantitative monitoring of the two processes is not trivial, and most studies seeking to characterize these processes fail to do so. In a recent publication in Human Gene Therapy Methods, BERG-iBB researchers working in collaboration with Centro de Química Física Molecular of IST, describe a tool that could offer simultaneous quantitative information on both the intracellular dissociation of lipoplexes, and on the DNA escape from endocytic compartments. This ability is expected to be of high value in the rationalization and conception of new lipid nanoparticle vectors for gene delivery for therapeutic purposes. Click on title to learn more.

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ASM Embassador Visits iBB

ASM Embassador Visits iBB | iBB | Scoop.it
The American Society for Microbiology (ASM) is the oldest and largest single life science membership organization in the world. Membership has grown from 59 scientists in 1899 to more than 39,000 members today, with more than one third located outside the United States. The members represent 26 disciplines of microbiological specialization plus a division for microbiology educators.
Miguel Prazeres's insight:

On Feb. 21, Tuesday, iBB will receive the visit of Dr. Diogo Proenca, Young Ambassador of Portugal to the American Society for Microbiology (ASM). The visit will include a presentation (14:30 H, meeting room 9th floor, South Tower) in which Dr. Proença will publicize the activities of the ASM and describe the advantages of being a member. 

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NATO Science for Peace and Security (SPS) Programme

NATO Science for Peace and Security (SPS) Programme | iBB | Scoop.it

"The NATO Science Programme for Peace and Security (SPS) is an important contributor  to the reinforcement of Euro-Atlantic efforts in international security, enhancing scientific and technological research and promoting international cooperation between NATO Member States and Allies.

The SPS Programme funds R&D multi-annual projects, specialised training sessions, and the organisation of workshops involving the scientific communities of Member States and, at least, one Allied Country. Projects can be funded with between 200 and 300 K€. Purchase of equipment is eligible."

Miguel Prazeres's insight:

A one-day long session on the SPS programme will take place on monday, the 20th of October at IST (starting a 10:00 am). Click on photo to learn more.

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Wageningen University PhD Students Visit IBB

Wageningen University PhD Students Visit IBB | iBB | Scoop.it

A group of 15 Ph. D. students and 3 staff members from the Bioprocessing Group of the University of Wageningen (NL) will be visiting IBB on the morning of the 23rd October, as part of their field trip to Portugal. A session will take place at the amphitheater of Complexo Interdisciplinar from 9 to 13 h where 2 PhD students from WU and 2 PhD students from IBB will have the opportunity to present their work. The students from WU will also have the opportunity to present their work in a dedicated poster session. All members of IBB are invited to participate (see program below and click on photo to go to Bioprocess Engineering @WU).

 

9:00-10:00   Welcome and Introductory presentations (WUR, IBB)

10:00-11:00 Tour IBB and Coffee break

11:00-12:00 PhD presentations (WUR, IBB)

12:00-13:00 Poster session and Closure

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Applications for iLLP@Tecnico Program Open

Applications for iLLP@Tecnico Program Open | iBB | Scoop.it

"The Innovation Lean LaunchPad (iLLP@Tecnico) is an acceleration program using the Lean LaunchPad framework. This framework incorporates the Customer Development Methodology (Blank 2005), the Lean Startup Movement (Ries 2011), the Business Model Canvas (Osterwalder 2010), in a flipped classroom blended learning environment. The iLLP@Tecnico program aims at moving technologies out of the lab and into the market, through talking to customers, partners and competitors and encountering the chaos and uncertainty of creating successful innovation."

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Luís Raiado to Defend PhD Thesis in Biotechnology

Luís Raiado to Defend PhD Thesis in Biotechnology | iBB | Scoop.it

Luís Miguel raiado Pereira will be defending his Ph D thesis in Biotechnology at Instituto Superior Técnico, thrusday the 9th October 2014 (14:30 H, room PA3). During the last years, and under the supervision of Marília Mateus and Miguel Prazeres from BERG-IBB, Luís 

developed membrane hydrophobic interaction chromatography (HIC) membranes based on alkyl and phenyl ligands and studied their applicability  in the downstream processing of plasmid DNA.  The title of the thesis is “Hydrophobic Interaction Membrane Chromatography for the Downstream Processing of Plasmid DNA”. 

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