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Miguel Fuzeta to Defend PhD Thesis in Bioengineering

Miguel Fuzeta to Defend PhD Thesis in Bioengineering | iBB | Scoop.it

 Miguel de Almeida Fuzeta will be defending his PhD thesis in Bioengineering on Wednesday the 27th october 2021 at 10:00 h (https://videoconf-colibri.zoom.us/j/81143862412). During the last years, and under the supervision of Cláudia Lobato Silva from SCERG and BERG-IBB and Diana Maria Diez Gaspar from FEUP, Miguel focused his efforts on the development of Bioprocesses for the scalable manufacturing of extracellular vesicles derived from mesenchymal stromal cells. The title of the thesis is “Scalable Production of Extracellular Vesicles Derived from Mesenchymal Stromal Cells for Cancer-Targeted Drug Delivery”.

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Ana Isabel Campos to Defend PhD Thesis in Biotechnology and Biosciences

Ana Isabel de Vila-Santa Braga Campos will be defending her PhD thesis in Biotechnology and Biosciences at Instituto Superior Técnico, Friday the 16th of April 2021, at 15:00 am (https://videoconf-colibri.zoom.us/j/81314376867). During the last years, and under the supervision of Nuno Mira and Frederico Ferreira from iBB, and Kristala Prather from MIT, Ana Isabel investigated how pathways for the synthesis of levulinic and itaconic acids can be engineered in yeasts. The title of her thesis is “Synthetic biology approaches to foster yeasts as hosts for the production of carboxylic acids and their derivatives: emphasis on levulinic and itaconic acids”.

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David Botequim to Defend PhD Thesis in Biotechnology and Biosciences

David Botequim to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

David José Roxo Botequim will be defending his PhD thesis in Biotechnology and Biosciences at Instituto Superior Técnico, Wednesday the 18th of November 2020, at 10:30 am (https://videoconf-colibri.zoom.us/j/89168693131). During the last years, and under the supervision of Pedro Paulo from CQE and Miguel Prazeres from BERG-iBB, David studied fluorescently-labeled DNA probes conjugated onto gold nanoparticles for the improved detection of nucleic acids. The title of his thesis is “Fluorescently-labeled DNA Probes Functionalized onto Gold Nanorods for Signal Enhancement in Nucleic Acids’ Detection”.

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Mafalda Cavalheiro to Defend PhD Thesis in Biotechnology and Biosciences

Mafalda Cavalheiro to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Mafalda Banazol de Santa Rita Cavalheiro will be defending her PhD thesis in Biotechnology and Biosciences at Instituto Superior Técnico, Monday the 12th of October 2020, at 2pm (https://videoconf-colibri.zoom.us/j/97930626637). During the last years, and under the supervision of Miguel Cacho Teixeira from BSRG-iBB, Mafalda studied molecular and biophysical properties that enable the fungal pathogen Candida glabrata to cause recalcitrant life threatening infections, based on its ability to evolve towards a drug resistance phenotype or to establish stable biofilms. The title of her thesis is “Deciphering Mechanisms of Pathogenesis in Candida glabrata: in the Crossroad Between Drug Resistance and Virulence”.

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André Nascimento Defends PhD Thesis in Biotechnology and Biosciences

André Nascimento Defends PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

André Nascimento defended his PhD thesis in Biotechnology and Biosciences on Monday the 6th april 2020 (14:00 H). During the last years, and under the supervision of Ana Azevedo from BERG-iBB and Steven Cramer and Pankaj Karande from the Rensselaer Polytechnic Institute (US), André developed and explored affinity peptides and multimodal ligands for the purification of Fab antibody fragments. The title of the thesis is “Development of a novel purification platform for Fab antibody fragments based on affinity peptides and multimodal ligands”.

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Ana Margarida Rosa to Defend PhD Thesis in Biotechnology and Biosciences

Ana Margarida Rosa to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Ana Margarida Rosa will be defending her PhD thesis in Biotechnology and Biosciences on Wednesday the 29th january 2020 (10:30 H, amphitheater PA-3, Mathematics Building). During the last years, and under the supervision of Miguel Prazeres from BERG-iBB and Pedro Paulo from CQE-IST, Ana developed a cellulose-based system for the colorimetric detection of nucleic acids by exploring the recognition of biotin-labeled DNA hybrids by anti-biotin antibodies immobilized through ZZ-CBM chimeric proteins. These fusions combine carbohydrate-binding modules (CBM) with affinity to cellulose and double Z domains (ZZ) that bind to IgG antibodies. The title of the thesis is “DNA recognition system on bioactive paper using fusions of carbohydrate-binding modules and IgG-binding Z domains”.

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Rita Franca to Defend PhD Thesis in Biotechnology and Biosciences

Rita Franca to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Rita Dias Guardão Moreira da Franca will be defending her PhD thesis in Biotechnology and Biosciences on tuesday the 5th November 2019 (14 H, amphitheater PA-3, Mathematics Building). During the last years, and under the supervision of Nídia Lourenço and Helena Pinheiro from BERG-IBB and Mark van Loosdrecht from TUDelft (The Netherlands), Rita studied the application of the novel aerobic granular sludge technology to the biodegradation of recalcitrant pollutants mainly found in textile industry wastewaters. She looked into the influence of wastewater composition and reactor operational regimens on the formation and stability of aerobic granules, microbial population dynamics in them and their performance in the biodegradation of wastewater components, namely an azo dye and its recalcitrant metabolites.

The title of the thesis is “Aerobic granular sludge bioprocesses for textile wastewater treatment”.

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Pedro Pais to Defend PhD Thesis in Biotechnology and Biosciences

Pedro Pais to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Pedro Henrique Magalhães Fernandes Pais will be defending his PhD thesis in Biotechnology and Biosciences at Instituto Superior Técnico, friday the 27th september 2019 (10:00 H, room PA-3). During the last years, and under the supervision of Miguel Teixeira from BSRG-iBB, Pedro studied the intricacies of the regulatory network that controls drug resistance in the fungus Candida glabrata. The title of his thesis is "Unveiling the complex regulatory network governing antifungal drug resistance in Candida glabrata: from new regulators to new effectors".

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Joana Serra to Defend PhD Thesis in Bioengineering

Joana Serra to Defend PhD Thesis in Bioengineering | iBB | Scoop.it

Joana Serra will be defending her PhD thesis in Bioengineering at Instituto Superior Técnico, friday the 7th June 2019 (10:30 H, room Q4.41). During the last years, and under the supervision of Miguel Prazeres from BERG-iBB and Cláudia Lobato-Silva from SCERG-iBB, Joana focused her efforts on the genetic modification of mesenchymal stem/stromal cells with VEGF-coding minicircles to improve their therapeutic features in the context of ischemia. The title of her thesis is "Ex-vivo gene therapy to improve the regenerative features of human mesenchymal stem/stromal cells (MSC) in a model of limb ischemia".

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IST-iBB Awards Sixteen PhD Degrees in Bioengineering and Biosciences in 2018

IST-iBB Awards Sixteen PhD Degrees in Bioengineering and Biosciences in 2018 | iBB | Scoop.it

Sixteen students successfully defended their PhD thesis (Bioengineering or Biotechnology and Biosciences) under the supervision of iBB Faculty and research scientists during the year 2018. Congratulations and best wishes to all!

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Francisco Moreira Defends PhD Thesis in Bioengineering

Francisco Moreira Defends PhD Thesis in Bioengineering | iBB | Scoop.it

Francisco Moreira has just defended his PhD thesis in Bioengineering (MIT Portugal) at Instituto Superior Técnico, wednesday the 12th December 2018 (14:00 H, room PA3). During the last years, and under the supervision of Joaquim Cabral and Cláudia Lobato Silva from SCERG-iBB, Francisco focused on the establishment of a scalable three-dimensional dynamic culture for the expansion of adipose tissue-derived MSC under xeno-free conditions. The title of his thesis is "Scalable Platform for the Expansion of Human Mesenchymal Stem/Stromal Cells Under Dynamic Conditions”.

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Marta Carvalho Defends PhD Thesis in Bioengineering

Marta Carvalho Defends PhD Thesis in Bioengineering | iBB | Scoop.it

Marta Monteiro Silva Carvalho will be defending her PhD thesis in Bioengineering (Cell Therapies and Regenerative Medicine) at Instituto Superior Técnico, tuesday the 4th December 2018 (14:00 H, room PA3). During the last years, and under the supervision of Cláudia Lobato Silva from SCERG-iBB and Deepak Vashisth from the Rensselaer Polytechnic Institute, Marta focused on the development of biomimetic 3-D matrices for stem cell mediated bone formation, with a particular interest on evaluating the influence of non-collagenous proteins present in the bone matrix. The title of her thesis is "Stem Cell-mediated bone formation on biomimetic 3-D matrices”.

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Teresa Silva Defends PhD Thesis in Bioengineering (Cell Therapies and Regenerative Medicine)

Teresa Silva Defends PhD Thesis in Bioengineering (Cell Therapies and Regenerative Medicine) | iBB | Scoop.it

Teresa Silva will be defending his PhD thesis in Bioengineering (MIT Portugal) at Instituto Superior Técnico, wednesday the 26th October 2018 (15:00 H, room PA3). During the last years, and under the supervision of Carmo Fonseca from IMM and Tiago Fernandes and Evguenia Bekman from SCERG-iBB, Teresa worked on the development of new models to study neurodegenerative diseases such as ataxias that are caused by dysfunction of the cerebellum. The title of her thesis is "Novel bioengineering strategies for modeling cerebellar ataxias”.

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Cláudia Alves to Defend PhD Thesis in Biotechnology and Biosciences

Cláudia Alves to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Cláudia Patrícia Almeida Alves will be defending her PhD thesis in Biotechnology and Biosciences at Instituto Superior Técnico, Friday the 14th of May 2021, at 14:00 am (https://videoconf-colibri.zoom.us/j/82471896554). During the last years, and under the supervision of Gabriel Monteiro and Miguel Prazeres from iBB, Cláudia engineered Escherichia coli strains for the production of minicircle vectors by resolvase-catalyzed in vivo recombination. The title of her thesis is “Escherichia coli Genome Engineering For Improved Minicircle Production". Yo can check more about Cláudia's work here.

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Andreia Pimenta to Defend PhD Thesis in Biotechnology and Biosciences

Andreia Pimenta to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Andreia Isabel de Melo Pimenta will be defending her PhD thesis in Biotechnology and Biosciences at Instituto Superior Técnico, Tuesday the 22nd of December 2020, at 10:00 am (https://videoconf-colibri.zoom.us/j/87589426644). During the last years, and under the supervision of Arsénio Fialho from BSRG-iBB, Andreia studied the role of Trimeric autotransporter adhesins in the pathogenesis of Burkholderia cenocepacia. The title of her thesis is “New insights into the interaction of Burkholderia cenocepacia with host cells: Trimeric autotransporter adhesins as pathogenicity factors”.

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Eduardo Brás Defends PhD Thesis in Biotechnology and Biosciences

Eduardo Brás Defends PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Eduardo Brás defended his PhD thesis in Biotechnology and Biosciences on Tuesday the 15th september 2020 (14:30 H). During the last years, and under the supervision João Pedro Conde from INESC-MN and Pedro Fernandes from BERG-iBB, Eduardo explored how microfluidic technology and microfabrication could be coupled with enzymes with goal of developing biosensing in different fields of application. The title of the thesis is “Biocatalysis in Microfluidic Systems: Biosensing and Rapid Screening Applications”.

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Rui Pacheco Defended PhD Thesis in Biotechnology and Biosciences

Rui Pacheco Defended PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Rui Cruz Pacheco defended his PhD thesis in Biotechnology and Biosciences on the 15th of April, 2020. The thesis, entitled “Production of first-and second-generation bioethanol by yeasts: global warming potential and fermentation productivity issues” was supervised by Carla Silva, Faculdade de Ciências da Universidade de Lisboa and Instituto Dom Luiz and co-supervised by Isabel Sá-Correia from BSRG-iBB. Rui prepared part of his PhD thesis in the laboratories of the BSRG examining factors that limit first-and second-generation fermentation productivity and improving industrial yeasts performance through genetic manipulation. Most of his work was dedicated to the Life Cycle Assessment (LCA) of bio-based ethanol production.

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Amir Hassan to Defend PhD Thesis in Biotechnology and Biosciences

Amir Hassan to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Ahmed Amir Elsayed Hassan will be defending her PhD thesis in Biotechnology and Biosciences on tuesday the 28th january 2020 (14:30 H, amphitheater PA-3, Mathematics Building). During the last years, and under the supervision of Isabel Sá-Correia from BSRG-iBB, Amir studied the role of the lipopolysaccharide O-antigen on the adaptation of the Bhurkolderia cepacia complex to the cystic fibrosis environment. The title of the thesis is “Adaptation of Bhurkolderia cepacia complex bacteria to the cystic fibrosis lung: focus on lipopolysaccharide O-antigen and cel wall physical properties”.

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Cátia Bandeiras to Defend PhD Thesis in Bioengineering

Cátia Bandeiras to Defend PhD Thesis in Bioengineering | iBB | Scoop.it

Cátia Filipa Medina Bandeiras will be defending her PhD thesis in Bioengineering (MIT Portugal Program) on Friday the 8th November 2019 (14 H, amphitheater PA-3, Mathematics Building). During the last years, and under the supervision of Frederico Ferreira from SCERG and BERG-IBB and Stan Finkelstein from MIT, Cátia developed an open-source framework for combined bioprocess and health economics modeling, aiming at the evaluation of stem cell engineering innovations towards the commercialization of stem cell-based therapies. She used this framework to evaluate the impact of manufacturing component choices, like culture media and expansion technologies, the scale of manufacturing, and the long-term cost-effectiveness of stem cell-based therapies for type 1 diabetes and cystic fibrosis. This computational approach, based on experimental data, provided cues for additional reductions in the cost of goods, and recommendations for precision medicine of these prospective therapies. The title of the thesis is “TESSEE – Tool for Early Stem Cells Economic Evaluation”

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João Carlos Silva to Defend PhD Thesis in Bioengineering

João Carlos Silva to Defend PhD Thesis in Bioengineering | iBB | Scoop.it

João Carlos Fernandes da Silva will be defending his PhD thesis in Bioengineering (Cell Therapies and regenerative Medicine) at Instituto Superior Técnico, friday the 27th september 2019 (14:00 H, room PA-3). During the last years, and under the supervision of Frederico Ferreira from SCERG-iBB and Robert Linhardt from RPI, João focused his efforts on the fabrication of hierarchical and biomimetic cartilage constructs. The title of his thesis is "Bioengineering strategies towards the in vitro fabrication of hierarchical and biomimetic cartilage constructs".

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Sara Rosa to Defend PhD Thesis in Biotechnology and Biosciences

Sara Rosa to Defend PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Sara Lourenço Rosa will be defending her PhD thesis in Biotechnology and Biosciencesat Instituto Superior Técnico, monday the 9th september 2019 (14:30 H, room PA-3). During the last years, and under the supervision of Ana Azevedo from BERG-iBB and Cláudia Lobato-Silva from SCERG-iBB, Sara explored phenyl boronate chromatography as an alternative technique to purify biomolecules such as antibodies. The title of her thesis is "A phenylboronate chromatography based approach as an effective alternative for downstream processing of biomolecules".

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Tânia Baltazar Defends PhD Thesis in Bioengineering

Tânia Baltazar Defends PhD Thesis in Bioengineering | iBB | Scoop.it

Tânia Daniela Cavaleiras Baltazar will be defending her PhD thesis in Bioengineering (Cell Therapies and Regenerative Medicine) at Instituto Superior Técnico, thursday the 21st March 2019 (12:30 H, room PA3). During the last years, and under the supervision of Frederico Ferreira from SCERG-iBB and Pankaj Karande from RPI, Tânia focused her efforts on the development of a 3D printed in vitro vascularized human skin model for clinical applications. The title of her thesis is "Design and Fabrication of Full-Thickness Vascularized Human Skin With 3D Bioprinting Technology”.

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Maria João Jacinto to Defend PhD Thesis in Bioengineering

Maria João Jacinto to Defend PhD Thesis in Bioengineering | iBB | Scoop.it

Maria João Jacinto will be defending her PhD thesis in Bioengineering at Instituto Superior Técnico, thursday the 7th March 2019 (10:30 H, room PA3). During the last years, and under the supervision of Raquel Barros and Ana Azevedo from BERG-iBB and Richard Willson from the University of Houston, Maria João focused her efforts on the development of platforms for the downstream processing and detection of VLPs and bacteriophages. The title of her thesis is "Integrative platforms for downstream processing and detection of viral particles”.

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Daniel Silva Defends PhD Thesis in Biotechnology and Biosciences

Daniel Silva Defends PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Daniel Filipe Camarneiro Silva will be defending his PhD thesis in Biotechnology and Biosciences at Instituto Superior Técnico, wednesday the 12th December 2018 (10:30 H, room PA3). During the last years, and under the supervision of Raquel Aires Barros from BERG-iBB and Virginia Chu from INESC-MN, Daniel focused on the development of aqueous two phase separation of monoclonal antibodies in microfluidic devices. The title of his thesis is "Microfluidic separation using aqueous two phase systems”.

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Raquel Cunha Defends PhD Thesis in Bioengineering (MIT Portugal)

Raquel Cunha Defends PhD Thesis in Bioengineering (MIT Portugal) | iBB | Scoop.it

Raquel Medina dos Santos Cunha will be defending her PhD thesis in Bioengineering (MIT Portugal) at Instituto Superior Técnico, tuesday the 20th November 2018 (10:30 H, room PA3). During the last years, and under the supervision of Cláudia Lobato Silva from SCERG-iBB, Jeffrey Karp from Harvard Medical School and António Fiarresga from Hospital de Santa Marta, Raquel worked on the development of platforms for the production and characterisation of clinical grade stem cell-based therapies with enhanced regenerative potential. The title of her thesis is "Towards the development of potency assays and 3D inflammation models to evaluate the regenerative potential of Mesenchymal Stem/Stromal Cell (MSC) and MSC-derived products”.

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