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Patent on the Biological Production of Xilonic Acid  Awarded to iBB Researchers

Patent on the Biological Production of Xilonic Acid  Awarded to iBB Researchers | iBB | Scoop.it

A biological process for the production of xylonic acid (XA) from xylose or from xylose-rich lignocellulosic hydrolysates has been patented by BERG-iBB researchers Teresa Cesário, Manuela Fonseca and Maryna Bondar (PT 115970). The ability of the wild strain Paraburkholderia sacchari (previously classified as Burkholderia sacchari) DSM 17165 to produce xylonic acid from renewable and sustainable feedstocks is claimed. XA is a potential substitute for gluconic acid (GA), namely in the pharma industry, as a chelating agent, as a precursor of 1,2,4-butanetriol, polyamides and polyesters, as well as in the production of solvents, paints, adhesives and dyes. Moreover, XA, like GA, can be used as a retardant of the setting time of cement paste. XA productivities in the range 4.8 g/(L.h) to 7.1 g/(L.h) and yields between 89% e 100% were achieved, with XA titres of 360 to 390 g/L, using one single, non-pressurised stirred tank reactor operating in the fed-batch mode under dissolved oxygen concentrations higher than 10%  saturation.

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US Patent Application on Cupredoxins Published

US Patent Application on Cupredoxins Published | iBB | Scoop.it

A US Patent application (application number 14/817063) co-authored by Arsénio Fialho from BSRG-iBB and by researchers from the University of Illinois headed by Prof. Ananda Chakrabarty has just been published. The innvention relates to compositions and methods of use of cupredoxins, and variants, derivatives and structural equivalents of cupredoxins that interfere with the ephrin signaling system in mammalian cells. Specifically, the invention relates to uses of cupredoxins, such as azurin, rusticyanin and plastocyanin, and variants, derivatives and structural equivalents thereof, to treat cancer in mammals. Click on title to learn more. 

Photo: 3D model of Rusticyanin from Thiobacillus ferrooxidans.

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PI@Técnico Days: I Have an Idea, But is it Original?

PI@Técnico Days: I Have an Idea, But is it Original? | iBB | Scoop.it

I have an idea, but is it original? Find it out at PI@Técnico days. The best way to value an invention is to file for a patent. The first and fundamental step in this process is to confirm that the idea is original. This is a critical task that requires you to search the right places and play close attention to the details. Organized by IST's Technology Transfer Office , the next session of the PI@Técnico Days will deal with this (September 26th, 4:30 pm, Room Q01). Get to know precious tips from an INPI examiner. Maybe you can turn your idea into a patent. Register here.

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