iBB
46.3K views | +21 today
Follow
iBB
Institute for Bioengineering and Biosciences
Curated by iBB
Your new post is loading...
Your new post is loading...
Scoop.it!

3D Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells

3D Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells | iBB | Scoop.it
Oligodendrocyte precursor cells (OPCs) offer considerable potential for the treatment of demyelinating diseases and injuries of the CNS. However, generating large quantities of high-quality OPCs remains a challenge that impedes their therapeutic application. In collaboration with researchers at the Stem Cell Engineering Research Group (SCERG), researchers at the Department of Bioengineering, University of California, Berkeley, have recently developed a novel defined and scalable culture system for differentiation of OPCs from Human Pluripotent Stem Cells, under 3D conditions, using a fully-defined thermoresponsive biomaterial. This system enabled the generation of large quantities of high-quality OPCs that were able to engraft, migrate and mature into myelinating oligodendrocytes upon transplantation into the brains of NOD/SCID mice.
No comment yet.
Scoop.it!

Gonçalo Rodrigues Defends PhD Thesis in Biotechnology and Biosciences

Gonçalo Rodrigues Defends PhD Thesis in Biotechnology and Biosciences | iBB | Scoop.it

Gonçalo Rodrigues will be defending his Ph D thesis in Biotechnology and Biosciences at Instituto Superior Técnico, thursday the 11th may 2017 (10:30 H, room PA3). During the last years, and under the supervision of Joaquim Cabral and Margarida Diogo from SCERG-iBB and David V. Schaffer from the University of California, Gonçalo focused his efforts on the study of neural differentiation for cell therapy applications. The title of Gonçalo's thesis is “Defined and Scalable Systems for Neural Differentiation of Human Pluripotent Stem Cells”.

No comment yet.