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Institute for Bioengineering and Biosciences
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GPCR Screening Assays: Methods and Protocols

GPCR Screening Assays: Methods and Protocols | iBB | Scoop.it

The book G Protein-Coupled Receptor Screening Assays: Methods and Protocols, edited by Sofia Martins from INESC-MN and Miguel Prazeres from BERG-iBB, has just been published. This fully updated edition targets not only those assays directly involved in the discovery of GPCR-active compounds but also those involved in cell-based experiments designed to study physiological responses. Whether coming from academia or industry, or being an experienced researcher or a newcomer to the field, the reader will find accessible methods and protocols that cover the latest developments on receptor purification, molecular biology, recombinant engineering, and analytical techniques that enable the real time monitoring of the complex GPCR signaling cascade and identification of potential drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Yeasts in Biotechnology and Human Health

Yeasts in Biotechnology and Human Health | iBB | Scoop.it

The book "Yeasts in Biotechnology and Human Health", edited by Isabel Sá-Correia from BSRG-iBB and featuring contributions from international researchers has just been released by Springer. The book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research.

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Microbial Infections and Cancer Therapy

Microbial Infections and Cancer Therapy | iBB | Scoop.it

The book "Microbial Infections and Cancer Therapy", co-edited by Arsénio Fialho from BSRG-iBB in collaboration with Ananda Chakrabarty (University of Illinois) has just been released by Pan Stanford Publishing. The book deals with the emerging concept that certain pathogenic bacteria and viruses, when infecting people with cancer, actively fight tumors, allowing their regression. It features 12 chapters written by pioneers in microbial, biotech, and cancer research and covers the emerging roles of various microorganisms and their products in cancer therapy. The book highlights the benefits of using conventional cancer treatments (such as chemo- and radiotherapies) with microbial-based therapies.

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José Menezes Co-Edits "A Lifecycle Approach to Knowledge Excellence in the Biopharmaceutical Industry"

José Menezes Co-Edits "A Lifecycle Approach to Knowledge Excellence in the Biopharmaceutical Industry" | iBB | Scoop.it

The book "A Lifecycle Approach to Knowledge Excellence in the Biopharmaceutical Industry", co-edited by José Cardoso Menezes from BERG-iBB in collaboration with colleagues Nuala Calnan (St. Gallen University), Martin Lipa (Merck) and Paige Kane (Merck) has just been released by CRC Press. The book addresses the rapidly emerging field of Knowledge Management in the pharmaceutical, medical devices and medical diagnostics industries. In particular, it explores the role that Knowledge Management can play in ensuring the delivery of safe and effective products to patients. The book also provides good practice examples of how the effective use of an organisation’s knowledge assets can provide a path towards business excellence. Click on title to learn more.

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Stem Cell Manufacturing

Stem Cell Manufacturing | iBB | Scoop.it

The book "Stem Cell Manufacturing", edited by Joaquim Cabral, Cláudia Lobato Silva and Margarida Diogo from SCERG-iBB, together with Chase from Cellular Dynamics International, edited by Elsevier in 2016, continues to serve as a reference for Bioengineers involved in bringing stem cells frm the lab to the clinic and market. The book discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product.

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Bioreactors for Stem Cell Expansion and Differentiation

Bioreactors for Stem Cell Expansion and Differentiation | iBB | Scoop.it

The book "Bioreactors for Stem Cell Expansion and Differentiation", edited by Joaquim Cabral and Cláudia Lobato Silva from SCERG-iBB has just been released by CRC Press. In the book, an international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological shortcomings that currently preclude advances towards product commercialization.

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Multivariate Analysis in the Pharmaceutical Industry

Multivariate Analysis in the Pharmaceutical Industry | iBB | Scoop.it

The book "Multivariate Analysis in the Pharmaceutical Industry", co-edited by José Cardoso Menezes from BERG-iBB in collaboration with colleagues Ana Patrícia Ferreira and Mike Tobyn from Bristol-Myers Squibb has just been released by Academic Press. The book seeks to put multivariate analysis into a pharmaceutical context for the benefit of pharmaceutical practitioners, potential practitioners, managers and regulators. Click on title to learn more.

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IBB Researchers Edit Book on GPCR Screening Assays

IBB Researchers Edit Book on GPCR Screening Assays | iBB | Scoop.it

The book G Protein Coupled Receptor Screening Assays: Methods and Protocols, edited by BERG-IBB researchers Sofia Martins and Miguel Prazeres, has just been published. The book reaches out to everyone involved in the discovery of GPCR-active drugs, and provides a transversal overview of the different levels of GPCR signaling addressable in the different screening strategies and presents practical examples of how current assay technologies are contributing to new paradigms in GPCR drug research. The book stems from the posto-doctoral work of Sofia Martins and features contributions from renowed specialists in the area. Click on title to learn more.

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