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Pharmacogenomics: The Future Of Prescribing?

Pharmacogenomics: The Future Of Prescribing? | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

Pharmacogenomics is the study of how genes affect a person’s response to drugs. This relatively new field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications and doses that will be tailored to a person’s genetic makeup. (U.S. National Library of Medicine)

It’s early days for pharmacogenomics, the study of how genes affect a person’s response to drugs. Our understanding of how particular genes and sets of genes interact with medications is still rather crude, but advancing at a rapid pace. Interestingly, much of this information is openly and immediately available through the internet, the primary mechanism for the democratisation of medical knowledge.

Before I continue with some specific examples, I do need to give a couple of caveats:

  • Not everything you read on the internet is true and/or accurate. In fact, my research shows that “the seeds of misinformation” + “the existence of confirmation bias” + “a large enough community” = “confident ignorance”. Sorry to break that to you. ��
  • It’s such early days for this emerging science that I would urge very great caution in making treatment decisions based on our current knowledge base.  I’m much more interested in exploring what pharmacogenomics will become in the next few years than what it is today.
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eHealth mHealth HealthTech innovations - Marketing Santé innovant
Digital, Apps, IoT, devices, AI / DL (...) innovations for Health and Healthcare
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Merck picks circular path to RNA and commits $250M to biotech startup Orna

Merck picks circular path to RNA and commits $250M to biotech startup Orna | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Merck aims to bolster its genetic medicines pipeline through a new research alliance with Orna Therapeutics, a startup whose technology forms RNA into a circle shape that brings several advantages for new therapies and vaccines. In addition to starting the partnership, the pharmaceutical giant also invested in Orna’s $221 million Series B financing round.
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Les mauvaises nouvelles s'accumulent pour Sanofi

Les mauvaises nouvelles s'accumulent pour Sanofi | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Mois d'août douloureux pour Sanofi. Le géant pharmaceutique, dont l'image avait déjà souffert de ses difficultés à développer un vaccin anti-Covid, inquiÚte désormais les marchés face à une accumulation de mauvaises nouvelles. «Sanofi met un terme au programme mondial de développement clinique de l'amcenestrant», a annoncé ce mercredi le groupe, faisant baisser son action de presque 5% à la Bourse de Paris. Cette molécule était destinée à lutter contre certains cancers avancés du sein. Mais Sanofi a pris acte d'essais cliniques insuffisamment probants.
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Handicap et démence : les start-up deeptech à la rescousse

Handicap et démence : les start-up deeptech à la rescousse | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
DĂ©couvrez le nouvel Ă©pisode de « If we impact the futur of
 », la sĂ©rie vidĂ©o qui questionne les enjeux technologiques futurs, lancĂ©e par le 3DEXPERIENCE Lab, l'accĂ©lĂ©rateur de Dassaul

Via Rémy TESTON
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Rescooped by Dominique Godefroy from GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK
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Apple is testing a noninvasive blood glucose monitor: CNBC

Apple is testing a noninvasive blood glucose monitor: CNBC | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Apple has tasked a team of 30 engineers with developing a continuous noninvasive blood sugar mo | Apple has tasked a team of 30 engineers with developing a continuous noninvasive blood sugar monitoring technology, according to CNBC. The initiative pits Apple against a technical challenge that has thwarted researchers for years—plus competitors including Alphabet’s Verily—in a push to create a device that frees diabetics from finger-prick blood glucose readings.

Via Lionel Reichardt / le Pharmageek
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Les applications mobiles de santé, utiles mais encore trop peu contrôlées

Les applications mobiles de santé, utiles mais encore trop peu contrôlées | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Selon une récente étude publiée dans le Journal of Medical Internet Research, 64% des applications de «e-santé» n'auraient pas réalisé d'étude clinique pour démontrer leur efficacité.

Les applications mobiles de santĂ© et de bien-ĂȘtre inondent les boutiques d'application pour smartphone depuis l'Ă©pidĂ©mie de Covid-19. Conçues pour amĂ©liorer notre qualitĂ© de vie, elles se nourrissent souvent d'informations sur nos comportements ainsi que de donnĂ©es mĂ©dicales. TantĂŽt outil de rappel, tantĂŽt outil de diagnostic, elles sont principalement utilisĂ©es pour offrir un plus grand sentiment d'autonomie aux patients. Mais ont-elles toutes un intĂ©rĂȘt mĂ©dical? Selon une rĂ©cente Ă©tude publiĂ©e dans le Journal of Medical Internet Research , 64% des applications de «e-santé» n'auraient pas rĂ©alisĂ© d'Ă©tude clinique pour dĂ©montrer leur efficacitĂ©. Seules 21% d’entre elles auraient rĂ©alisĂ© des Ă©tudes randomisĂ©es, mĂ©thode la plus courante pour prouver la fiabilitĂ© scientifique d'un produit.
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Rescooped by Dominique Godefroy from GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK
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Amazon Care partnering with Ginger to add mental health services

Amazon Care partnering with Ginger to add mental health services | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Amazon Care, which currently offers virtual health visits, in-person primary care visits at patients' homes or offices and prescription delivery, is adding behavioral health care to its slate of se | Amazon Care, which currently offers virtual health visits, in-person primary care visits and prescription delivery, is adding behavioral health care to its slate of services.

Via Lionel Reichardt / le Pharmageek
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New revelations from monkeypox outbreak study

New revelations from monkeypox outbreak study | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Unique skin symptoms of the current monkeypox outbreak include pseudo-pustules

A review of 185 cases of monkeypox – published in the British Journal of Dermatology – has found that the main features of the current outbreak differ from past cases.

Pivotally, the research found that the main symptom is not pustules, as previously described, but much rarer ‘pseudo-pustules’.

The research, conducted by a network of Spanish dermatologists, categorised key features of the current monkeypox outbreak. The 185 cases studied represent 9% of those reported to the Spanish national surveillance system by 11 July 2022.
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J.D. Power: Mail-order pharmacies a threat to retail stores

J.D. Power: Mail-order pharmacies a threat to retail stores | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Patients are much more comfortable getting routine healthcare at brick-and-mortar pharmacies than they were in the past, thanks in large part to them having to flock to those pharmacies during the COVID-19 pandemic.

However, companies such as Amazon, which provide mail-order service, represent a growing threat to retail pharmacies, at least in terms of how patients purchase their medications.
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Diagnostic Robotics raises $45M for AI-enabled care management and more digital health fundings

Diagnostic Robotics raises $45M for AI-enabled care management and more digital health fundings | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Diagnostic Robotics, which offers AI tools for population health management and triaging patients to the best care site, announced last week it had raised $45 million in Series B funding.

The round was led by StageOne investors with participation from investors including Mayo Clinic, Technion – Israel Institute of Technology and Berkshire Partners cofounder Bradley Bloom. The startup said the funds will go toward product development and investment in sales and marketing, as well as new hires.

"Diagnostic Robotics is using the most precise predictive models, leveraging nuanced definitions of risk and shifting focus away from purely risk-based targeting to clinically-actionable targeting to not only change how health plans approach their members, but to drastically improve member clinical care journeys," CEO Kira Radinsky said in a statement.
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La santé en danger face aux cybermenaces visant l'IoT

La santé en danger face aux cybermenaces visant l'IoT | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

Les appareils médicaux dont dépendent les soins dans la quasi-totalité des établissements sont menacés par des cyber-attaques visant l'IoT.

La quasi-totalitĂ© des Ă©tablissements de santĂ© français (97.3 %) ont mis en oeuvre des dispositifs mĂ©dicaux connectĂ©s qui doivent donc ĂȘtre considĂ©rĂ©s comme relevant de l'IoT selon une Ă©tude rĂ©alisĂ©e par Soti. Depuis la crise sanitaire Covid-19, 57 % ont mis en place des dispositifs de tĂ©lĂ©santĂ© et 51 % des dispositifs portables (wearable) de suivi des patients. Logiquement, 73 % des Ă©tablissements ont augmentĂ© leurs investissements dans les nouvelles technologies depuis 2020. Si ces outils ont une utilitĂ© certaine, leur dĂ©ploiement ne se fait pas toujours dans le respect des meilleures pratiques et il en rĂ©sulte bien des risques, notamment sur les donnĂ©es sensibles.

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Fait(s) ! Bilan de la feuille de route du numérique en santé 2019 - 2022 | esante.gouv.fr #hcsmeufr #esante

Fait(s) ! Bilan de la feuille de route du numérique en santé 2019 - 2022 | esante.gouv.fr #hcsmeufr #esante | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Retour sur ces trois ans d’aventure collective

Via Lionel Reichardt / le Pharmageek
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JMIR mHealth and uHealth | Remote Automated Blood Pressure Monitoring With Wearable Tech

JMIR mHealth and uHealth | Remote Automated Blood Pressure Monitoring With Wearable Tech | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
JMIR Publications recently published "Continuous Noninvasive Remote Automated Blood Pressure Monitoring With Novel Wearable Technology: A Preliminary Validation

Via Lionel Reichardt / le Pharmageek
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AI in health care pharmacovigilance

AI in health care pharmacovigilance | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Discover how artificial intelligence in health care is enhancing pharmacovigilance and how the future of pharmacovigilance will be impacted by AI in health care.

Via Lionel Reichardt / le Pharmageek
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MHRA authorises Moderna’s omicron-containing bivalent booster

MHRA authorises Moderna’s omicron-containing bivalent booster | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Study results show the candidate has demonstrated significantly higher antibodies against Omicron

Moderna has announced that the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK has granted conditional authorisation for the use of Omicron-containing bivalent COVID-19 booster vaccine, mRNA-1273.214

The treatment, which is also known as Spikevax Bivalent Original/Omicron – will be used as a booster dose for active immunisation to prevent COVID-19 caused by SARS-CoV-2 in individuals of 18 years and older. Spikevax Bivalent Original/Omicron is a next-generation bivalent vaccine that contains mRNA-1273 (the current authorised booster) and a vaccine candidate targeting the Omicron variant of concern.
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DeepMind offre aux chercheurs une représentation de toutes les protéines humaines

DeepMind offre aux chercheurs une représentation de toutes les protéines humaines | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Le 28 juillet 2022, la recherche en biologie a peut-ĂȘtre fait un pas de gĂ©ant grĂące Ă  l'intelligence artificielle. Google DeepMind, le laboratoire britannique d'IA du groupe Alphabet, a fait don Ă  la communautĂ© scientifique de ses rĂ©sultats concernant les prĂ©dictions de structure molĂ©culaire de l'ensemble des 200 millions de protĂ©ines connues. Soit 200 fois les connaissances dĂ©jĂ  disponibles dans la base de donnĂ©es que la sociĂ©tĂ© avait mis Ă  disposition des chercheurs il y a un an. On ne connaĂźt prĂ©cisĂ©ment la structure que de 17% des protĂ©ines prĂ©sentes dans le corps humain.
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Des neurones artificiels un million de fois plus rapides que les nôtres

Des neurones artificiels un million de fois plus rapides que les nôtres | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Produire des neurones artificiels plus efficaces que les neurones humains
 l’idĂ©e n’est pas nouvelle. Des chercheurs du MIT viennent cependant de l’emmener Ă  un tout autre niveau. Ils affirment avoir crĂ©Ă© un rĂ©seau de neurones artificiel capable de fonctionner un million de fois plus vite que chez l’Homme.

Via Philippe Serafin
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Le Sénat lance le chantier de la carte Vitale biométrique

Le Sénat lance le chantier de la carte Vitale biométrique | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
PrĂŽnĂ© en solution ultime pour rĂ©pondre Ă  la fraude sociale, le lancement de la carte Vitale biomĂ©trique a Ă©tĂ© votĂ© par le SĂ©nat le 3 aoĂ»t. Longtemps rĂ©clamĂ© par la droite et l’extrĂȘme droite, rejetĂ© une premiĂšre fois il y a deux ans par la majoritĂ© prĂ©sidentielle, le dispositif peine Ă  convaincre les professionnels de santĂ©.

Via Lionel Reichardt / le Pharmageek
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Enquête Data : Les chiffres clés de la pharma

Enquête Data : Les chiffres clés de la pharma | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it


Comment l’industrie pharma est-elle en train de digĂ©rer la crise du Covid-19 ? La pandĂ©mie a propulsĂ© certains laboratoires vers les...-laboratoires-pharma


Via Lionel Reichardt / le Pharmageek
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Boehringer’s digital rewards club boosts COPD medication adherence by 44%: study

Boehringer’s digital rewards club boosts COPD medication adherence by 44%: study | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Forget Klondike bars—what would you do for an Amazon gift card? | The RespiPoints program initially launched in 2016 with support for Spiriva Respimat, one of Boehringer’s inhaler-based prescription treatments for symptoms of COPD.

Via Lionel Reichardt / le Pharmageek
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Unused inventory, production capacity added up for Moderna in Q2

Unused inventory, production capacity added up for Moderna in Q2 | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
While new polls show flatlining concern about the pandemic among Americans, Moderna's COVID-19 vaccine business continues quietly churning in the background. But amid a recent decline in vaccine demand, the company has written off a sizable chunk of inventory.

In its second-quarter results announcement, Moderna said it wrote off $499 million in inventories "related to COVID-19 products that have exceeded or are expected to exceed their approved shelf-lives prior to being used." In addition, the company took a $184 million charge because of changes in prior purchase committments, and it recorded an expense of $131 million for "unutilized external manufacturing capacity."
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Alnylam drug succeeds in heart study, setting stage for FDA filing and showdown with Pfizer

Alnylam drug succeeds in heart study, setting stage for FDA filing and showdown with Pfizer | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Alnylam Pharmaceuticals drug Onpattro, an FDA-approved treatment for nerve pain caused by hereditary transthyretin amyloidosis, now has Phase 3 data showing it can also help the much larger group of patients suffering heart problems from the rare protein disease. An FDA submission is planned, which would pit the Alnylam drug in competition with a blockbuster Pfizer product.
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Janssen spotlights 'HIV Heroes' at global AIDS conference

Janssen spotlights 'HIV Heroes' at global AIDS conference | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Johnson & Johnson’s Janssen unit is tapping the power of storytelling in its new four-part "HIV Heroes" series, created with LGBTQ+-owned media company equalpride.

Ciara “CiCi” Covin was just 20 and a college student in 2008 when she learned she was HIV-positive. Today, the mother of two has a leading role in a nonprofit that advocates for women living with HIV.
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Oui Pharma aide les pharmacies à trouver des repreneurs et des salariés

Oui Pharma aide les pharmacies à trouver des repreneurs et des salariés | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
"On lisait dans la presse que des pharmacies peinaient Ă  trouver des repreneurs et de l’autre, que des candidats Ă  la reprise ne trouvaient pas de pharmacies", explique AurĂ©lien Filoche, directeur gĂ©nĂ©ral et co-fondateur de Oui Pharma avec son associĂ© Guillaume Campo, lui-mĂȘme pharmacien. Les deux hommes ont eu l’idĂ©e en 2015 de crĂ©er une plateforme pour donner de la visibilitĂ© aux offres et mettre en relation les diffĂ©rentes parties. Chaque annĂ©e, 1500 pharmacies se vendent en France.
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Covid long : une intelligence artificielle aide à le reconnaître

Covid long : une intelligence artificielle aide à le reconnaître | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

Cette IA compare les donnĂ©es mĂ©dicales d’un patient avant et aprĂšs qu’il ait eu le covid pour prĂ©dire s’il a un Covid long, avec plus de 80% de rĂ©ussite.

Lire l'article complet sur : www.sciencesetavenir.fr


Via Lionel Reichardt / le Pharmageek
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Attention aux apps santé pour smartphone qui ne sont pas homologuées

Attention aux apps santé pour smartphone qui ne sont pas homologuées | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Le secteur de la e-santé est un secteur florissant qui profite aux développeurs d'applications : quelque 90.000 solutions de cybersanté ont vu le jour rien que cette année, soit 250 par jour

Via Lionel Reichardt / le Pharmageek
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