Gene circuit switches on inside cancer cells, triggers immune attack
Researchers at MIT have developed a synthetic gene circuit that triggers the body’s immune system to attack cancers when it detects signs of the disease.
The circuit, which will only activate a therapeutic response when it detects two specific cancer markers, is described in a paper published to...
Computational Social Scientist Beware: Simpson's Paradox in Behavioral Data
When building models of human systems understanding Simpson's paradox is essential for creating behaviorally accurate representations
Cell-like lipid vesicles which can be populated with natural cell proteins
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Gene circuit switches on inside cancer cells, triggers immune attack
Researchers at MIT have developed a synthetic gene circuit that triggers the body's immune system to attack cancers when it detects signs of the disease.
Human Mobility: Models and Applications
This is a comprehensive review of mobility methods that are  essential for emergent models of disease, transportation, traffic and economics among other applications,. Worth reading.
Designing Drugs Aimed at a Different Part of Life’s Code
Most drugs work by tinkering with the behavior of proteins. Like meddlesome coworkers, these molecules are designed to latch onto their target proteins and keep them from doing what they need to do.
Scientists demonstrate path to linking the genome to healthy tissues and disease
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New toolkit reveals novel cancer genes 
A new statistical model has enabled researchers to pinpoint 27 novel genes thought to prevent cancer from forming, in an analysis of over 2000 tumours across 12 human cancer types. The findings could help create new cancer treatments that target these genes, and open up other avenues of cancer re...
Life’s First Molecule Was Protein, Not RNA, New Model Suggests 
Which mattered first at the dawn of life: proteins or nucleic acids? Proteins may have had the edge if a theorized process let them grow long enough to become self-replicating catalysts.
Zika DNA Vaccine Proven Safe 
Very welcome news regarding initial ZIka virus trials.
New antibody attacks 99% of HIV strains
This possibly the most promising news in HIV treatment research in over a decade. A research collaboration between the US National Institutes of Health and the pharmaceutical company Sanofi has produced a new antibody for treatment of AIDS. Developed from three "broadly neutralising antibodies", that a small number of patients develop in response to HIV infection, the new antibody has been shown to be effective to 99% of HIV strains in vitro tests with monkeys. Human trials start next year. to see the BBC article click the picture. To see the full paper - see here
Powering the internet of things | August 7, 2017 Issue - Vol. 95 Issue 32 | Chemical & Engineerin...
Powering sensors over the long time periods is key to sensor network related developments in  environmental monitoring and industrial internet of things. By recouping ambient energy as a power sources for sensors - deployed duration times can become measured in years and decades rather than weeks and months. Good article on changes in sensor power sources  designers can expect to be available soon.
Conquering HIV’s capsid | July 31, 2017 Issue - Vol. 95 Issue 31 | Chemical & Engineering News
First potential new novel treatment for HIV in 10 years leverages the geometry of the HIV Capsid
Contagious disruptions and complexity traps in economic development
Poor economies not only produce less; they typically produce things that involve fewer inputs and fewer intermediate steps. Yet the supply chains of poor countries face more frequent disruptions---delivery failures, faulty parts, delays, power outages, theft, government failures---that systematic...
A Guide to Temporal Networks
Network science offers a powerful language to represent and study complex systems composed of interacting elements from the Internet to social and biological systems. In its standard formulation, this framework relies on the assumption that the underlying topology is static, or changing very slow...
CompleNet 2018 - 9th Conference on Complex Networks
Given the growth discipline complex network analysis tools and techniques, nthis could be a must do conference for 2018. Definitely one for the calendar. 
A generalized model of social and biological contagion
We present a model of contagion that unifies and generalizes existing models of the spread of social influences and micro-organismal infections. Our model incorporates individual memory of exposure to a contagious entity (e.g., a rumor or disease), variable magnitudes of exposure (dose sizes), an...
Zika virus evolution and spread in the Americas
One hundred and ten Zika virus genomes from ten countries and territories involved in the Zika virus epidemic reveal rapid expansion of the epidemic within Brazil and multiple introductions to other regions.

Zika virus evolution and spread in the Americas
Hayden C. Metsky, et al.
Nature 546, 41...
Characterizing information importance and the effect on the spread in various graph topologies
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[1706.05043] The thermodynamic efficiency of computations made in cells across the range of life
Biological organisms must perform computation as they grow, reproduce, and evolve. Moreover, ever since Landauer's bound was proposed it has been known that all computation has some thermodynamic cost -- and that the same computation can be achieved with greater or smaller thermodynamic cost depe...
Thermodynamics of Evolutionary Games
How cooperation can evolve between players is an unsolved problem of biology. Here we use Hamiltonian dynamics of models of the Ising type to describe populations of cooperating and defecting players to show that the equilibrium fraction of cooperators is given by the expectation value of a therm...
Chinese urbanization 2050: SD modeling and process simulation
Is Chinese urbanization going to take a long time, or can its development goal be achieved by the government in a short time? What is the highest stable urbanization level that China can reach? When can China complete its urbanization? To answer these questions, this paper presents a system dynam...
Why teach modeling & simulation in schools?
Advancements in science and technology take place on a global scale without much consideration of the exact implications that they may essentially have on the species or our planet. Over the last few decades, things are moving very fast and not always in a good way. The climate of the planet is c...
Complexity research in Nature Communications
This web collection showcases the potential of interdisciplinary complexity research by bringing together a selection of recent Nature Communications articles investigating complex systems. Complexity research aims to characterize and understand the behaviour and nature of systems made up of many...
A decade of discovery: CRISPR functions and applications
Great insight and perspective on CRISPR  developments and applications - worth reading.
Influenza: A viral world war
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The Types Of Cancer You Can Get From HPV
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Viral vectors travel longer distances than previously thought
Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells. In a study on mice
[1706.05043] The thermodynamic efficiency of computations made in cells across the range of life
The concept of computation as it occurs in biology is fascinating and this paper is likely to become a-classic - worth reading.
What a Fish Knows: The Inner Lives of Our Underwater Cousins
One for the reading list - looks fascinating.
Africa health: Rotavirus vaccine could save 500,000 children a year
As if we need a reminder on the importance of vaccinations. 
Host and viral traits predict zoonotic spillover from mammals
Understanding zoonotic potential will be key to health planning and epidemic prevention in the 21st century.  This paper has key insights such as major hosts (bats) and key geographic zones for observation. If you are involved in health planning or disease modeling - very worthwhile reading.
Genetics may lie at the heart of crop yield limitation - EurekAlert (2017) 
You might think that plants grow according to how much nutrition, water and sunlight they are exposed to, but new research... shows that the plant's own genetics may be the real limiting factor.

"This could have potentially big implications for the agricultural industry... Our model plant is i...
A Safety and Efficacy Study of TALEN and CRISPR/Cas9 in the Treatment of HPV-related Cervical Int...
If your tracking CRISPR/Cas9 applications - this is worth reviewing.
CRISPR-Cas Genome Surgery in Ophthalmology
While the promise of CRISPR was not that it would change how genetics and biology behaved its quickly becoming hyped that way in popular press.  The fact that the Cas9 protein can be used as a cheap and fast technique to co-localize with specific DNA sequences is undoubtedly incredibly useful. As researchers discover mechanisms where they can exploit co-localization and modification at specific sites using DNA cleavage capabilities it is important we get well informed reviews of actual applications as well as coverage of potential ones.  This paper gives a good summary of recent developments and insights to applications of CRISPR-CAS in ophthalmology  for both better understanding visual systems and potential treatments for ophthalmic disease. 
Models and people: An alternative view of the emergent properties of computational models
Computer models can help humans gain insight into the functioning of complex systems. Used for training, they can also help gain insight into the cognitive processes humans use to understand these systems. By influencing humans understanding (and consequent actions) computer models can thus gener...
Mapping the patent landscape of synthetic biology for fine chemical production pathways
A goal of synthetic biology bio-foundries is to innovate through an iterative design/build/test/learn pipeline. In assessing the value of new chemical production routes, the intellectual property (IP) novelty of the pathway is important. Exploratory studies can be carried using knowledge of the p...
Adaptive Computation: The Multidisciplinary Legacy of John H. Holland
I first came across John Holland's work in a an article while I was at High School some 30 years ago. A few years later he kindly answered my questions in an out of the blue phone call and then over the years in conversations at conferences and in emails.  I have always been in awe of the breadth of his vision and interests, intrigued by his ideas and appreciated the fact he would take time to encourage research and passionate discussion. Sadly with his passing last year - we lost a truly original insight. Stephanie Forrest and Melanie Mitchells article for the ACM captures the breadth of his interests, his wonderful legacy of ideas and perhaps more importantly  the example he set in his humanity and generosity. Well worth reading.
Organisms might be quantum machines
Interesting article on the increasingly suspected role of quantum physics in everyday biological systems including photosynthesis and migratory bird navigation. A fun read.
A Bird’s-Eye View of Nature’s Hidden Order | Quanta Magazine
If you want to understand why AI is beginning to make major breakthroughts - it helps to understand the physics underpinning our world. This article gives a good overview of one such physical property - hyperuniform that is neither regular or random but a distribution that reflects the constrained reality that biological systems evolve within. Very much worth reading.
Samsung pours $1.2 billion into the Internet of Things
Samsung is willing to put its money where its mouth is when it comes to the Internet of Things. The electronics giant is spending $1.2 billion on Io
Engineering and Assembly of Protein Modules into Functional Molecular Systems
The concept  of assembling native or engineered proteins and/or synthetic components into functional systems is a key goal of synthetic biollogy and this paper gives  a good overview of current state of the art . Worth reeading
MIT Engineers Developed a Super Strong Artificial Skin
Engineers from MIT have developed a substance that could be used as an artificial skin, long-lasting contact lens, drug-delivering bandage, and more.
‘Robot scientist’ Eve could speed up search for new drugs
Though it will take time, the combination of automated biological assay screening with synthetic biology and goal driven targetting will be a key development in personalized medicine, targetted drug development and disease treatments in the  21st century.
Battling the Zika virus, one old tyre at a time
Dr. Gerardo Ulibarri, PhD, an associate professor of medicinal chemistry and eco-health at Laurentian University in Sudbury, Ontario, had a  brilliant insight recycling tyres to create an effective mosquito trap that may provide an easy to build and effective mosquito management solution. Made from recycled tyres the bottom half of the device gets filled with about 2 litres of water, topped with so-called “landing strips” – pieces of Pellon or germinating paper, for example – on which the female mosquitoes lay eggs. Mosquitoes weed moisture to hatchso the landing paper if white easily shows the eggs. About once per week the user empties the device destroy the eggs, pour the water back into the ovillanta (topping it off with fresh water) and install two new landing strips. “It’s important to recycle the water because after the eggs hatch, they release a pheromone into the water that tells other mosquitoes it’s a good, safe place to lay eggs,” says Ulibarri, who’s work is funded by Grand Challenges Canada. BBC article very worth reading
Whatever happened to 'bans' on GM produce in British supermarkets? - Conversation (2015)
In the late 1990s, Sainsbury’s and Safeway... both offered GM tomato purée... GM and non-GM cans of purée stood side by side on their shelves, the former some 18% cheaper... The cans were conspicuously labelled and pamphlets explaining what GM was all about were to hand nearby. But when the stock...
Chemicals That Make Plants Defend Themselves Could Replace Pesticides - Elsevier (2015)

Its good to see more research in these areas - but it would be good if in parallel we looked at potential impact of activated and elevated triggers and response  in terms of ecosystems and human health.  Multi-systemic approaches are going to be increasingly needed, which is worrying given how limited funding in this area already is..

The role of environmental biotechnology in exploring, exploiting, monitoring, preserving, protect...

late publishing this - but been on track list for some time. Also worth looking at the 2015 report on protection zones - where some progress has been made. See



Information Dynamics in the Interaction between a Prey and a Predator Fish

Interesting use of entropy for information transfer in predator-prey interactions.  Good paper - worth reading and a lot worth thinking  further about.

Agent-based Simulations of a Logistic System

Agent based simulastion of logistics is becoming increasingly commmon - nice example.

Fast and slow thinking -- of networks: The complementary 'elite' and 'wisdom of crowds' of amino ...
Complex systems may have billion components making consensus formation slow and difficult. Recently several overlapping stories emerged from various disciplines, including protein structures, neuroscience and social networks, showing that fast responses to known stimuli involve a network core of ...
A new threat to bees? Entomopathogenic nematodes used in biological pest control cause rapid mort...
There is currently a great deal of concern about population declines in pollinating insects. Many potential threats have been identified which may adversely affect the behaviour and health of both honey bees and bumble bees: these include pesticide exposure, and parasites and pathogens.

Can CRISPR Avoid the Monsanto Problem?
It is distressing, but a fact, that the more rapidly any technology is adopted by scientists the more likely it is to leave people confused, anxious, and suspicious. This week, I wrote an article for the magazine about just such a revolutionary technique, called CRISPR, that permits scientists to...
First CRISPR Gene Drive in Mosquitoes Aims to Eradicate Malaria
The students in Anthony James’s basement insectary at the University of California, Irvine, knew they’d broken the laws of evolution when they looked at the mosquitoes’ eyes.

By rights, the bugs, born from fathers with fluorescent red eyes and mothers with normal ones, should have come out onl...
Mouse Colon Colonized with Human Microbiota

Its a small world - and a stunning photogaph. Examining occurances of microbiota and how they travel between species has a lot of implications for understanding healthcare and disease reservoirs. 

Forecasting Metastatic Breast Cancer’s Path in a Patient

Since this touches on some of our own research areas - the paper is a must read and an excellent piece of research more importantly its hopefully a major step forward in helping find effective treatment for metastatic cancer. An excellent example of systems modelling and applying insights from one field to another.

Mathematical Models Key to Designing Better Cancer Treatment Strategies

Models of cancer that are benchmarked against actual occurances and correctly predict behaviour are critically important for devising fruture treatments. Good intro to the subject.

Information Dynamics in the Interaction between a Prey and a Predator Fish
Accessing information efficiently is vital for animals to make the optimal decisions, and it is particularly important when they are facing predators. Yet until now, very few quantitative conclusions have been drawn about the information dynamics in the interaction between animals due to the lack...
The Hidden Power Laws of Ecosystems - Issue 29: Scaling - Nautilus

Interesting article - from an ecologists point of view on many of the topics and areas of research familiar to complex adaptive systems researchers but applied against actual ecosystems.

Motorcycle runs on water and can travel 310 miles on a single litre
Footage shows Sao Paulo-based public officer Ricardo Azevedo filling his 'T Power H20’ motorcycle with clean water and water from the polluted Tiete River before going for a spin.

He said: ‘The advantage of this motorcycle, which works with the hydrogen that comes from the water, is that the r...
Biopython: freely available Python tools for computational molecular biology and bioinformatics
"The Biopython project is a mature open source international collaboration of volunteer developers, providing Python libraries for a wide range of bioinformatics problems."
The storytelling scientist
"Why a lack of narrative in science is a problem and why better narratives could mean better scientific communication."
PLOS Computational Biology: Ten Simple Rules for Creating a Good Data Management Plan

Good article - along with workflows - data management lifecycle and scientifiic workflow lifecycle management are critical in quality research and likely gowth areas in lifesciences tech for quite some time. Worth reading.

6 Rules For Great Storytelling, From A Moth-Approved Master Of The Form

We all have to communicate and knowing how to tell a story and related a good yarn is increasingly a key skill. Worth reading.

Scope and Opportunities of Bioengineering and Biotechnology in Agriculture and Related Industries...

Having grown up  in a northumberland mining village in the north east of England, surrounded by farming and small woodlands - agriculture is something i think of intimately interwound with industry and how we live. If you grew up in a city - it can seem distant, but its always fundamental. If you grew up around farms - you know they are places of high and low tech. Strains and breeds are early forms of bio-engineering, agricultural equipment gives access to pragmatic engineering principles early on. In the coming decades advanced in bioengineering and biotech will increasingly be larger components of modern agriculture in order to meet increasing population pressures and demands generated by increased urban living. This report clearly helps identify the opportunities and possibilities and policy requirements that exist. If you are tracking the technology aspects of modern agriculture or interested in how agriculture will ahve to change to address increasing social needs - this report is well worth reading.

Scaling synthetic biology from lab to market | Karen Polizzi

Good discussion on issues of scaling synthetic biology - worth watching if you have 5 mins.

Making big data work: smart, sustainable, and safe cities

Interesting results of Telecom Italia's 2014 Bid Data Challenge - if smart cities are of interest  - worth reading.

Artificial vanillin receptor modulates transcription - PLOS Synthetic Biology Community
Bacteria adjust to different environmental conditions mainly by modulating transcription. Internal and external stimuli affect regulatory elements, all of which formulate the complex transcriptional profile of an organism at any given moment. In synthetic biology, the use of synthetic genetic cir...
Scope and Opportunities of Bioengineering and Biotechnology in Agriculture and Related Industries...
p. 305-313: With Asia having some of the fastest-growing economies with over 60% of the world’s population, 34% of the world’s arable land, and 36% of the world’s water resources, the region’s need to overcome formidable challenges and improve its total agricultural production and agricultural pr...
From robotics to analytics, why NASA is offering startups over 1,000 patents for 'free' | ZDNet

bookmarking for follow up reading.

So It Turns Out There's A Lot We Don't Know About Ebola
New data on survivors shows a range of health problems, from loss of vision to arthritis. It's making researchers realize they need to learn more about how the virus affects the human body.
Cross-boundary Behavioural Reprogrammability of Cellular Automata from Emulation Networks

Cellular automata are such a simple delightful and deeply compelling - good discussion of their value in looking into inherent complexity of systems

Toward a unifying framework for evolutionary processes

Interesting paper - however any paper discussing an approach to a unifying evolutionary process that discusses genetic algorithms is somewhat of a remis when doing a recap and missing John H Holland's pioneering work.   That said still worth reading.

Study shows algal virus can infiltrate mammalian cells
New research led by the University of Nebraska-Lincoln has provided the first direct evidence that an algae-infecting virus can invade and potentially replicate within some mammalian cells.Known as Acanthocystis turfacea chlorella virus 1, or ATCV-1, the pathogen is among a class of chloroviruses...
Database of host-pathogen and related species interactions, and their global distribution
Interactions between species, particularly where one is likely to be a pathogen of the other, as well as the geographical distribution of species, have been systematically extracted from various web-based, free-access sources, and assembled with the accompanying evidence into a single database. T...
Toby Bloom - "Infrastructure for the Next Generation of Genomic Analysis" | Center for Computatio...

Just the intro to the talk alone provides good insight into challenges and complexities facing todays biologist and bioinformatics workers. - Hopefully presentation will be posted in full later.

IndieBio Will Accelerate Synthetic Biology To Tech Startup Speed - Forbes

IndieBio will likely be a bell weather  fro how life sciences are adapting to accelerated rates of innovation and discovery - as well as a center point for policy, public perception and discourse. Good article - worth reading for insight into life sciences and biotech incubation as of 2015.

DIELMO 3D Provides Geospatial Back-Office for UAV, Heli, Fixed-Wing and ... -

IF you are involved in developing or using professional mapping, survey and photogrammetric products -  Dielmo  have released their back office cloud platform that enables teams to  upload, store, process and share LiDAR, Raster, Vector data derived from UAV, Helicopter, Fixed-wing and Mobile platforms.  Helping data acquisition companies to benefit from the latest in sensor and big data processing technologies, reducing the complexity of data processing and data analysis means Dielmo can help professional cartographers and cartographic solution developers - save time to market and operations costs. 

Jupiter Systems Announces Strong Sales for Canvas, its Game Changing ... - Business Wire (press r...

Canvas is one of a new generation of collaboration and integration tools that are changing how organisations think of enterprise PC applications. If you are involved in data fusion and sensor integration its worth tracking.

Don't close the door on open science - The Hill (blog)

Open science is critically important to future development and increasingly under attack from a wired varied of scources - sadly including the government - worth reading.

At the Far Ends of a New Universal Law | Quanta Magazine

Systems of many interacting components — be they species, integers or subatomic particles — kept producing the same statistical curve, which had become known as the Tracy-Widom distribution. This puzzling curve seemed to be the complex cousin of the familiar bell curve, or Gaussian distribution, which represents the natural variation of independent random variables like the heights of students in a classroom or their test scores... click on title to read more.

The Thermodynamic Theory of Ecology | Quanta Magazine

Awesome article on the Maximum Entropy (MaxEnt) theory proposed by John Harte, professor of ecology at University of California, Berkeley. MaxEnt is a key tool to help calculate the total number of species in ecosystem based on very limited information.

Choosing the right estimator — scikit-learn 0.15.1 documentation

Knowing which machine learning method to apply for a given problem takes time to learn - fortunately the fine folks over at have created a quick visual cheatsheet that helps understand which algorithm to apply in which context. Very helpful.

How the zebra got its stripes, with Alan Turing

Alan Turing’s published  his ‘chemical morphogenesis’ research  paper in 1952, 2 years before his tragic and untimely death. The paper opened the discussion on how computation and biology may be at fundamentally linked, a thread which continues to be ripe with exploration today. Great article from Mosaic Science explaining the ideas in turings paper and the 60 years of subsequent research.


The man who grew eyes

Interesting article on the work of Yoshiki Sasai  a Japanese biologist and Director of the Laboratory for Organogenesis and Neurogenesis at the research institute RIKEN in Kobe, Japan. Sasai was best known for developing new methods to grow stem cells into organ-like structures

NIH Categorical Spending -NIH Research Portfolio Online Reporting Tools (RePORT)

Table of US research expenditure  estimates by NIH for various research, health conditions and disease categories.

Forests and human health

This prescient report from the FAO in 2009 highlights why research on EIDs, particularly that involving the ecological epidemiology of zoonotic and vector-borne diseases associated with forests, needs to be integrated with forest resource management and planning and healthcare management planning. This report along with related publications from FAO are essential reading for anyone modeling ecological change and disease impact. Very much worth reading.

Outbreak of Ebola Virus Disease in Guinea: Where Ecology Meets Economy

As terrifying and tragic the current Ebola outbreak is - informed discussion on sources, vectors and the interplay of ecology and socioeconomics will be at the heart of finding long term solutions.

Deforestation, development may be driving Ebola outbreaks, experts say | Al Jazeera America

After publishing the link to the paper on ebola antibodies in fruitbats in Bangladesh - wespeculated and were asked regarding deforestation impact - this is a good overview article discussing some of the current discussion points.

Ebola Virus Antibodies in Fruit Bats, Bangladesh - Volume 19, Number 2—February 2013 - Emerging I...

As evidence builds that fruit bats may be a vector for the recent ebola outbreak in Western Africa - I was reminded of this paper in CDC's EID journal which found 5 out of 276 (3.5%) tested bats in Bangladesh had antibodies to Ebola. It would be interesting to map ebola outbreaks against natural migration and deforestation paths and see if there is any correlation and to see how other regional antibody presence tests indicate migration as well. The original paper and the EID journal in general are well worth reading. Click image or headling to read more.



I Contain Multitudes | Quanta Magazine

With new methods of single cell DNA sequencing becoming available - biologists are beginning to look a the degrees of variations that exist across cells and the extent of cell to cell diversity and what this implies for biological adaptation.

CUDA Toolkit

New CUDA 6 toolkit release with 64-bit arm support, improved CUDA Fortran for scientific aplications, replay features in visual profiler and nvprof and a new BLAS GPU library cublasXT that scales across GPUs. A lot of goodness for compute developers - available here:

Oracle Cranks Up The Cores To 32 With Sparc M7 Chip

It has often been easy to forget following the acquisition of Sun by Oracle - Oracle have continued investing in hardware. The new M7 chip line with 64 sparc cores and Numa interconnect options not only continues to promise speed increases for existing oracle customers but also shows benefits over off the shelf clusters of highly integrated large core systems using optimised connection architectures. Good in depth article - worth reading.

Are Agent-Based Models the Future of Macroeconomics?

Been a while since we published anything on economics but with over 20 years experience building agent based models - we are suckers for articles that encourage people to discover them as thinking tools. Good explanation on how agent based models fit into economic forecasting.

How CDC Uses Antibiotic Resistance Data - Food Safety News

CDC are one fo the organisations leading information release on antimicrobial resistance. This article explaines where to find out more info from CDC on this area. Worth reading.

Why HIV Virions Have Low Numbers of Envelope Spikes: Implications for Vaccine Development

Interesting paper on structural protien envelope spikes in HIV related viruses and their relation to autoimmune response and implications for vaccine development by John Schiller and Bryce Chackerian. 

Do-It-Yourself Biology? Messing Around with DNA Increasingly a Garage-Band Venture
Programmable on-chip DNA compartments as artificial cells

At Radcliffe Institute of Advanced Study at Harvard, Roy Bar-Ziv is expanding his research to explore the paradigm of programmable on-chip DNA compartments as artificial cells, in which the essential reactions of living cells encoded in DNA take place inside miniaturized compartments fabricated in silicon. Understanding the emergent properties of these compartments may lead to assembly of artificial cells capable of computation, autonomous sensing, and replication, with applications in future technologies.

First ever biological amplifier created by Imperial scientists

Click title or image to learn more.

Limits on fundamental limits to computation

Discussion of limits is key to creating new ideas - Igor Markov's paper is worth reading for exploring lmitations and engineering implications and to trigger off new discussions and ideas. Worth reading.