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Q&A: Early diagnosis critical in treating encephalitis due to COVID-19, other causes

Feb. 22 marks World Encephalitis Day, a day of global awareness started by the Encephalitis Society for individuals “who have been directly or indirectly affected by encephalitis,” which now includes patients with COVID-19.Healio Neurology spoke with Omar K.
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Testing for N-methyl-D-aspartate receptor autoantibodies in clinical practice

Testing for N-methyl-D-aspartate receptor autoantibodies in clinical practice | AntiNMDA | Scoop.it
The diagnosis of anti-N-methyl-D-aspartate receptor (NMDAR)
encephalitis relies on the detection of NMDAR IgG autoantibodies in the
serum or cerebrospinal fluid of symptomatic patients. Commercial kits are
available that allow NMDAR IgG autoantibodies ...
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Co-occurrence of Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Anti-myelin Oligodendrocyte Glycoprotein Inflammatory Demyelinating Diseases: A Clinical Phenomenon to Be Taken Seriously

Co-occurrence of Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Anti-myelin Oligodendrocyte Glycoprotein Inflammatory Demyelinating Diseases: A Clinical Phenomenon to Be Taken Seriously | AntiNMDA | Scoop.it
Background: Anti-N-methyl-D-aspartate receptor (NMDAR) immunoglobulin G antibodies which exist on myelin sheaths, composed of oligodendrocytes, especially target GluN1 subunits and are highly characteristic of anti-NMDAR encephalitis which is a newly recognized autoimmune encephalitis (AE) ch
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Pediatric anti-NMDA receptor encephalitis associated with COVID-19

Pediatric anti-NMDA receptor encephalitis associated with COVID-19 | AntiNMDA | Scoop.it
Anti-N-methyl-D-aspartate receptor encephalitis is a clinical condition characterized by acute behavioral and mood changes, abnormal movements, autonomic instability, seizures, and encephalopathy.We describe a 7-year-old boy diagnosed with autoimmune encephalitis due to NMDAR antibody in associatio...
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Lincoln model raising awareness of brain disease that saw her wrongly sectioned under Mental Health Act | Calendar

Lincoln model raising awareness of brain disease that saw her wrongly sectioned under Mental Health Act | Calendar | AntiNMDA | Scoop.it
A woman from Lincoln who was sectioned after being wrongly diagnosed as mentally ill is raising awareness of what happened to her.
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Anti-NMDA receptor antibodies in patients with a first episode of schizophrenia

Anti-NMDA receptor antibodies in patients with a first episode of schizophrenia | AntiNMDA | Scoop.it
Encephalitis with antibodies against N-methyl-D-aspartate receptor (NMDA-R) is classified as an autoimmune disorder with psychotic symptoms, which are frequently dominant. However, it remains unclear how frequently NMDA-R antibodies lead to a condition ...
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Palilalia as a prominent feature of anti-NMDA receptor encephalitis in a woman with COVID-19

Palilalia as a prominent feature of anti-NMDA receptor encephalitis in a woman with COVID-19 | AntiNMDA | Scoop.it
Palilalia as a prominent feature of anti-NMDA receptor encephalitis in a woman with COVID-19
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Anti-NMDA receptor encephalitis associated with ovarian tumor: the gynecologist point of view

Anti-NMDA receptor encephalitis associated with ovarian tumor: the gynecologist point of view | AntiNMDA | Scoop.it
Anti-NMDA antibody encephalitis should not be ignored by gynecologists whose role in management is central.
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Pediatric N-Methyl-d-Aspartate (NMDA) Receptor Encephalitis, With and Without Herpes Encephalitis - Lydia Marcus, Jayne M. Ness, 2021

Pediatric N-Methyl-d-Aspartate (NMDA) Receptor Encephalitis, With and Without Herpes Encephalitis - Lydia Marcus, Jayne M. Ness, 2021 | AntiNMDA | Scoop.it
Objective:To compare clinical, diagnostic, management, and outcome factors in children with anti–N-methyl-d-aspartate receptor (NMDAR) encephalitis and a history of herpes simplex encephalitis (HSE...
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Oculomotor artefacts mimic extreme deltabrush EEG features of autoimmune anti NMDA receptor encephalitis - ScienceDirect

Oculomotor artefacts mimic extreme deltabrush EEG features of autoimmune anti NMDA receptor encephalitis - ScienceDirect | AntiNMDA | Scoop.it
Clinical Neurophysiology Available online 31 March 2021 Letter to the Editor Oculomotor artefacts mimic extreme deltabrush EEG features of autoimmune anti NMDA receptor encephalitis Author links open overlay panel Show more Share Cite View full text © 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.
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Residual Fatigue and Cognitive Deficits in Patients After Leucine-Rich Glioma-Inactivated 1 Antibody Encephalitis | Dementia and Cognitive Impairment | JAMA Neurology | JAMA Network

Residual Fatigue and Cognitive Deficits in Patients After Leucine-Rich Glioma-Inactivated 1 Antibody Encephalitis | Dementia and Cognitive Impairment | JAMA Neurology | JAMA Network | AntiNMDA | Scoop.it
This study evaluates residual fatigue and cognitive defects in patients after leucine-rich glioma-inactivated 1 antibody encephalitis.
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MOG-IgG Among Participants in the Pediatric Optic Neuritis Prospective Outcomes Study | Demyelinating Disorders | JAMA Ophthalmology | JAMA Network

MOG-IgG Among Participants in the Pediatric Optic Neuritis Prospective Outcomes Study | Demyelinating Disorders | JAMA Ophthalmology | JAMA Network | AntiNMDA | Scoop.it
This study examines the association of myelin oligodendrocyte glycoprotein immunoglobulin G–associated disorder with pediatric optic neuritis to guide prognosis...
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Horizontal Saccadic Palsy as a Prominent Symptom of Anti-NMDAR Encephalitis | Neurology Clinical Practice

Horizontal Saccadic Palsy as a Prominent Symptom of Anti-NMDAR Encephalitis | Neurology Clinical Practice | AntiNMDA | Scoop.it
SHARE February 2021; 11 (1) CASE Horizontal Saccadic Palsy as a Prominent Symptom of Anti-NMDAR Encephalitis Koen Delmotte, Thomas Claeys, Koen Poesen, Bénédicte Dubois, Maarten Schrooten, Josep Dalmau, Robin Lemmens First published October 16, 2019, DOI: https://doi.org/10.1212/CPJ.0000000000000750 FULL PDF CITATION PERMISSIONS MAKE COMMENT SEE COMMENTS Downloads53 This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased. Consider the diagnosis of autoimmune encephalitis in patients with progressive disorders of voluntary eye movements in the context of encephalopathy. Footnotes Funding information and disclosures are provided at the end of the article. Full disclosure form information provided by the authors is available with the full text of this article at Neurology.org/cp. Received June 24, 2019. Accepted September 9, 2019. © 2019 American Academy of Neurology View Full Text AAN Members We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page. Google Safari Microsoft Edge Firefox CLICK HERE TO LOGIN AAN Non-Member Subscribers CLICK HERE TO LOGIN Purchase access For assistance, please contact: AAN Members (800) 879-1960 or (612) 928-6000 (International) Non-AAN Member subscribers (800) 638-3030 or (301) 223-2300 option 3, select 1 (international) Sign Up Information on how to subscribe to Neurology and Neurology: Clinical Practice can be found here  Purchase Individual access to articles is available through the Add to Cart option on the article page.  Access for 1 day (from the computer you are currently using) is US$ 39.00.  Pay-per-view content is for the use of the payee only, and content may not be further distributed by print or electronic means.  The payee may view, download, and/or print the article for his/her personal, scholarly, research, and educational use.  Distributing copies (electronic or otherwise) of the article is not allowed. YOU MAY ALSO BE INTERESTED IN Back to top Advertisement RELATED ARTICLES No related articles found. TOPICS DISCUSSED Autoimmune diseases ALERT ME
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Clinical Characteristics and Outcome of Neuronal Surface Antibody-Mediated Autoimmune Encephalitis Patients in a National Cohort

Clinical Characteristics and Outcome of Neuronal Surface Antibody-Mediated Autoimmune Encephalitis Patients in a National Cohort | AntiNMDA | Scoop.it
<span><b>Background:</b> In our previous single-center study of autoimmune encephalitis (AE) related autoantibody test results we found positivity in 60 patients out of 1,034 with suspected AE from 2012 through 2018 as part of a Hungarian nationwide program.
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Service Dogs Are Not For Petting, They're Keeping People Alive

Service Dogs Are Not For Petting, They're Keeping People Alive | AntiNMDA | Scoop.it
Please do not touch a service dog. My Auggie may be cuter than oxygen monitors and feeding tubes, but she is every bit as important.
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Recurrent anti-NMDAR encephalitis during pregnancy combined with two antibodies positive

Recurrent anti-NMDAR encephalitis during pregnancy combined with two antibodies positive | AntiNMDA | Scoop.it
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune synaptic encephalitis likely mediated by neuronal surface antibody. Clinically, it is characterized by a variety of neurological and psychiatric symptoms, predominantly affecting young women.
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Cells | Free Full-Text | Neurodegeneration Induced by Anti-IgLON5 Antibodies Studied in Induced Pluripotent Stem Cell-Derived Human Neurons

Cells | Free Full-Text | Neurodegeneration Induced by Anti-IgLON5 Antibodies Studied in Induced Pluripotent Stem Cell-Derived Human Neurons | AntiNMDA | Scoop.it
Anti-IgLON5 disease is a progressive neurological disorder associated with autoantibodies against a neuronal cell adhesion molecule, IgLON5. In human postmortem brain tissue, the neurodegeneration and accumulation of hyperphosphorylated tau (p-tau) are found.
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Remission of subacute psychosis in a COVID-19 patient with an anti-neuronal autoantibody after treatment with intravenous immunoglobulin

Remission of subacute psychosis in a COVID-19 patient with an anti-neuronal autoantibody after treatment with intravenous immunoglobulin | AntiNMDA | Scoop.it
COVID-19 patients are at increased risk for developing new or recurrent psychosis.(1) Viral infections—including SARS-CoV-2 (2-4)—can cause psychosis in the context of autoimmune encephalitis.(5) However, some individuals with para-infectious psychosis do not meet criteria for autoimmune...
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Autoimmune Encephalitis in Autism

Autoimmune Encephalitis in Autism | AntiNMDA | Scoop.it
Autoimmune encephalitis, inflammatory diseases of the brain, present with a wide range of neurological and psychiatric symptoms, most of them common in autism...
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COVID‐19 and anti‐N‐methyl‐d‐aspartate receptor (anti‐NMDAR) encephalitis: Are we facing an increase in the prevalence of autoimmune encephalitis? - Zandifar - 2021 - Journal of Medical Virology

COVID‐19 and anti‐N‐methyl‐d‐aspartate receptor (anti‐NMDAR) encephalitis: Are we facing an increase in the prevalence of autoimmune encephalitis? - Zandifar - 2021 - Journal of Medical Virology | AntiNMDA | Scoop.it
Click on the article title to read more.
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Clinical Features and Outcomes of Anti-N-Methyl-d-Aspartate Receptor Encephalitis in Infants and Toddlers

Clinical Features and Outcomes of Anti-N-Methyl-d-Aspartate Receptor Encephalitis in Infants and Toddlers | AntiNMDA | Scoop.it
Anti-NMDAR encephalitis in infants and toddlers clinically presents with movement disorders, developmental regression, and abnormal behaviors. Interestingly, this group had a higher proportion of patients after viral encephalitis, which is regarded as the only risk factor for poor outcomes.
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Hystero-epilepsy in the Tuesday Lessons and NMDA receptor function: A hypothesis for dissociative disorder

Hystero-epilepsy in the Tuesday Lessons and NMDA receptor function: A hypothesis for dissociative disorder | AntiNMDA | Scoop.it
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis patients demonstrate characteristic multistage progression and movement disorders, which are analogous to hystero-epilepsy in Jean-Martin Charcot's Tuesday Lessons.
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Brain on Fire disease: Regina woman recovering in hospital | CTV News

Brain on Fire disease: Regina woman recovering in hospital | CTV News | AntiNMDA | Scoop.it
Kerry Wallen began to display strange behaviour: confusion, repeating herself, showing signs of memory loss. Here's what doctors discovered.
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Familial autoimmunity in neurological patients with GAD65 antibodies: an interview-based study | SpringerLink

Familial autoimmunity in neurological patients with GAD65 antibodies: an interview-based study | SpringerLink | AntiNMDA | Scoop.it
The common co-occurrence of autoimmune systemic diseases in patients with neurological disorders and antibodies against glutamic acid decarboxylase 65 (GAD65) suggests a shared genetic predisposition to these disorders.
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Autoimmune Movement Disorders: A Video-Based Case Series of 11 Patients

Autoimmune Movement Disorders: A Video-Based Case Series of 11 Patients | AntiNMDA | Scoop.it
Autoimmune encephalitis (AIE) constitutes an important treatable cause of movement disorders.We aimed to highlight the spectrum of movement disorder and other salient features of AIE patients diagnosed at our tertiary care centre and describe their clinical symptoms, diagnostic approach, treatment,...
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Autoimmune encephalitis after Japanese encephalitis in children: A prospective study

Autoimmune encephalitis after Japanese encephalitis in children: A prospective study | AntiNMDA | Scoop.it
In addition to anti-NMDAR antibodies, anti-GABA<sub>B</sub>R antibodies and antibodies against unknown neuronal surface antigens can trigger autoimmune encephalitis following JE. Patients who developed autoimmune encephalitis had a poorer prognosis at the one-year follow-up.
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