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Rescooped by Lindsay Fletcher from Global Aquaculture News & Events!

The Aquaculturists: BioMar and Lallemand Animal Nutrition extend their collaboration

The Aquaculturists: BioMar and Lallemand Animal Nutrition extend their collaboration | Animal Nutrition |

The fish feed supplier, BioMar, and the feed additives and specialty functional feed ingredients manufacturer, Lallemand SAS, have signed a formal research, development and commercial collaboration agreement aimed at expanding the knowledge and use of probiotics in fish feeding.

“This agreement is a natural continuation of the excellent relationship forged with Lallemand Animal Nutrition for more than 10 years, which has led to important innovative landmarks such as the approval for the first time of the use of a probiotic in fish feeding by the European Food Safety Authority - Lallemand’s BACTOCELL® for use in fish feed” said Mr Torben Svejgaard, CEO of the BioMar Group at the occasion of the sealing of their latest agreement.

BioMar has since 2010, when the first EFSA approval was given, been the only feed supplier to offer fish feed with BACTOCELL®. With the extension of the EU approval earlier this year to all fish species, BioMar has launched additional new products with BACTOCELL®. These include the highly successful LARVIVA ProStart targeted at early weaning for fish larvae, as well as other types of fish feed such as the INICIO Plus fry feed for Mediterranean fish species.

”Lallemand Animal Nutrition sees a natural ally in BioMar with both companies equally devoted to funding robust research and development aimed at effective commercialization of products” said Dr Yannig Le Treut, GM of Lallemand Animal Nutrition. “We are also both committed to seeking sufficiently high level of understanding and well documented support for the natural solutions we offer to our customers. BACTOCELL® is still the only zootechnical additive approved by the European Food Safety Authorities for use in fish feed, having unequivocally demonstrated beneficial animal performances.

Dr Le Treut added: “On the development stance, a partnership with BioMar gives us access to both trial facilities for fish feeding as well as access to the extensive network BioMar has among fish farmers; providing willing sites and capabilities to enable testing of new feed solutions in “real life” situations. This has proven to be very effective and beneficial e.g. in the approval of BACTOCELL® where laboratory results were subsequently confirmed in field trials under industrial production conditions.”

The current agreement consolidates an already substantial research and development collaboration between the two companies. “We have from both sides allocated significant amounts of resources in a bid to continue to fund research which provides tangible, natural and economic solutions with regards to optimizing fish health, nutrition and welfare. In particular and at the moment we are looking at the effects of probiotics on the microbiome and on gut function, which has been hypothesized to be linked to the prevention of viral and bacterial outbreaks”, voiced by Dr Patrick Campbell and Dr Mathieu Castex in charge of the joint R&D programmes.

The agreement grants BioMar an exclusivity partnership with Lallemand on the use of BACTOCELL® in fish feed in all the key markets where BioMar operates. “We see a huge potential for the use of probiotics in fish feed, and we are therefore of course extremely pleased with this collaboration, which will extend our lead with these kinds of products” says Mr Torben Svejgaard.
Whilst the current agreement focuses on the use of probiotics, both Lallemand and BioMar admit that future agreements could extend to other areas of research, development, additives and animal categories of mutual interest. Lallemand Animal Nutrition already supplies several other important additives and ingredients to the fish feed industry and new actives are currently being evaluated in aquatic species.

Via Perendale Publishers (Tuti Tan)
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Purina Animal Nutrition launches enhanced pig starter feed - All about feed

Purina Animal Nutrition launches enhanced pig starter feed - All about feed | Animal Nutrition |
Purina Animal Nutrition launches enhanced pig starter feed
All about feed
Purina Animal Nutrition has launched a newly reformulated line of the UltraCare pig starter feed products – and showcases this at this year's World Pork Expo.
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Levucell SB At World Pork Expo | Lallemand Animal Nutrition

Levucell SB At World Pork Expo | Lallemand Animal Nutrition | Animal Nutrition |
Ernest Keith of Lallemand was interviewed at the Lallemand booth at World Pork Expo to discuss Levucell SB, a live active yeast.
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How Do Organs Know When They Have Reached the Right Size?

How Do Organs Know When They Have Reached the Right Size? | Animal Nutrition |

Development is, literally, the journey of a life time, and it is a trip still as mysterious as it is remarkable. Despite new methods to probe how an animal or plant forms from a single cell, biologists have much to learn about the unimaginably complex process. To identify some of the field’s persistent riddles, Senior Editors Beverly Purnell and Stella Hurtley and the news staff of Science have consulted with developmental biologists on our Board of Reviewing Editors and elsewhere. The mysteries offered here are a humbling reminder that our knowledge of development remains to a great extent embryonic.


Developmental biologists have found dozens of proteins and genes that play a role in the growth of plants and animals, such as imaginal discs and Hippo and morphogenetic proteins, but not what determines organ size.


A variety of experiments have shown that both the size of imaginal discs and the organs they form are very tightly controlled. When researchers transplant the wing imaginal disc from an early fly larva to a later one or vice versa, the wing still reaches normal size despite having different growing times. If researchers kill a portion of the imaginal disc cells with radiation or other techniques, the insect can boost cell division and still form a normal-size adult. If a fly receives just a fragment of a disc as a transplant, the animal won’t move to the next stage of development until the disc has reached the correct size—pausing overall development to allow the disc to catch up. The transplanted disc “will know what size it should be,” says developmental biologist Savraj Grewal of the University of Calgary in Canada.


Many researchers suspect that a developing organ somehow senses the mechanical forces on its growing and dividing cells. One theory is that relative crowding and stretching of cells helps determine whether a cell continues to divide or stops.


The size of an organ depends not only on how many cells it has, but also how big those cells are. Some developing organs—plant leaves, for example, and fruit fly wings—can compensate when fewer cells are available by making the individual cells larger. How a leaf knows when to expand its cells is also unclear, says Hirokazu Tsukaya, a developmental biologist at the University of Tokyo who was among the first to characterize the phenomenon in leaves. He and his team have evidence that some sort of cell-to-cell communication drives the process. Here, too, the evidence suggests that a plant doesn’t count cells but can somehow assess the overall size of a leaf, says plant biologist Beth Krizek of the University of South Carolina in Columbia. “But the mechanism of how that works is another mystery.”


The size of tissues, and ultimately an overall organism, also clearly depends on signals from the environment, which researchers call extrinsic factors. Those size control systems are connected to, but different from, the intrinsic systems that help ensure an organism is correctly proportioned. In plants, growth can be especially sensitive to such outside factors, Krizek notes, because they can’t move. Plants growing in shade, for example, concentrate on stem growth—to reach the sun—instead of leaf development. In animals, the amount of nutrition available can strongly influence the final size of some organs. One dramatic instance is the horn on a rhinoceros beetle. The horn is a sexually selected trait; males with bigger horns get access to more females. Recent studies have shown that the size of the horn is particularly sensitive to insulin signaling, which is related to the beetle’s nutrition. That, in turn, signals the animal’s overall fitness(Science, 27 July 2012, p. 408).

The problem of size control is still a fundamental one for developmental biologists, says Peter Lawrence of the University of Cambridge in the United Kingdom. Together with shape, size “is the material that evolution largely works on.” But the field is still mostly in the dark. Despite hundreds of papers on what happens when the Hippo signaling pathway is interrupted, Lawrence notes, what scientists really need to understand is what it does when it is working properly. “That is not something we know.”


Via Dr. Stefan Gruenwald
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