Time-lapse imaging of cell death in cell culture and whole living organisms using turn-on deep-re...
Cell death is a central process in developmental biology and also an important indicator of disease status and treatment efficacy.Two related fluorescent probes are described that are molecular conjugates of one or two zinc dipicolylamine (ZnDPA) coordination complexes with an appended solvatochr...
The zinc transporter SLC39A7 (ZIP7) is essential for regulation of cytosolic zinc levels
Zinc homeostasis is a highly regulated process in mammalian cells that is critical for normal growth and development. Movement of zinc across cell compartments is controlled by two classes of transporters: Slc39a family members transport zinc into the cytosol from either the extracellular space o...
The Association between Minerals and Gastric Cancer
Purpose: Study the role of minerals in gastric carcinogenesis.Materials and methods: Three hundred blood samples were used to analyze the status of concentration of Selen..
Three-minute thesis: Zinc and human health | Cosmos
How important is the role of zinc in diabetes treatment?
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Depen...
Purpose: ZIP4 is overexpressed in human pancreatic cancer and promotes tumor growth. However, little is known about the role of ZIP4 in advanced stages of this dismal neoplasm. Our goal is to study the underlying mechanism and define a novel signaling pathway controlled by ZIP4-modulating...
ISZB 2019 – The 6th Meeting for International Society for Zinc Biology
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Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases
Review Article...
Zinc: A Potential Antiviral Against Hepatitis E Virus Infection?
Hepatitis E virus (HEV) is a major cause of viral hepatitis worldwide. Owing to its feco oral transmission route, sporadic as well as epidemic outbreaks recurre...
In situ redox reactions facilitate the assembly of a mixed-valence metal-organic nanocapsule
New approaches are required to access metal-organic assemblies with unusual structural properties. Here, the authors use an in situ redox reaction to obtain a mixed-valence, Mn(II)/Mn(III)-containing metal-organic nanocapsule with an odd number of metal ions.
Zinc finger proteins discovered by MRC-funded research used in first gene-editing trial
MRC-funded research from Sir Aaron Klug’s lab at the MRC Laboratory of Molecular Biology underpins a historic gene editing trial run by a US biotechnology company. Scientists are attempting to edit a gene inside a body for the first time, to permanently change a person’s DNA to cure a disease.