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One step closer to cell reprogramming

One step closer to cell reprogramming | zen | Scoop.it
Researchers have discovered the essential role played by the Wnt pathway in the cell reprogramming process.
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A roadmap for metabolic reprogramming of aging | KurzweilAI

A roadmap for metabolic reprogramming of aging | KurzweilAI | zen | Scoop.it

To survey previously uncharted territory, a team of researchers at UW-Madison has created an “atlas” that maps more than 1,500 unique landmarks within mitochondria that could provide clues to the metabolic connections between caloric restriction and aging.

 

The map, as well as the techniques used to create it, could lead to a better understanding of how cell metabolism is rewired in some cancers, age-related diseases and metabolic conditions such as diabetes.

 

 


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Reprogramming Stem Cells

Open ‘back door’: How to reprogram cells

In healthy bodies, liver cells beget liver cells, while skin cells beget skin cells. Previous research, however, has shown that—sometimes—cells can be reprogrammed. This phenomenon has stumped scientists because there are cellular mechanisms in place to prevent such changes from occurring.

New research the University of Southern California shows how proteins called transcription factors can reprogram genes that have been turned off, shedding light on what happens when a cell’s fate changes course and why. The findings appear in the journal Cell.


Via Sakis Koukouvis
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