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The Last Laughing Death

The Last Laughing Death | Virology News | Scoop.it
A captivating story of love, death, cannibalism and a 50-year medical riddle in the hills of Papua New Guinea.

 

Thanks +AJ Cann!

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
Curated by Ed Rybicki
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Could Growing Vaccines in Plants Save Lives? [YES!!]

This flu season has been nasty in large part because the vaccine didn’t work as well as past versions. So scientists are on the hunt for new ways to mak
Ed Rybicki's insight:
I am a little biased, but still.
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Avian flu detected among seabird species

19 Feb 2018: The Department of Agriculture on Monday confirmed that the highly pathogenic H5N Avian flu detected among seabird species
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Kenya: Rollout of HPV Vaccine Deferred as Demand Grows

A national rollout of free cervical cancer vaccine that was to kick off this year has been pushed to 2019, the Sunday Nation has learnt.
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Full-genome sequencing of porcine circovirus 3 field strains from Denmark, Italy and Spain demonstrates a high within-Europe genetic heterogeneity

Transbound Emerg Dis. 2018 Feb 16. doi: 10.1111/tbed.12836. [Epub ahead of print]
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In the fight against HIV, cows emerge as powerful secret weapon

In the fight against HIV, cows emerge as powerful secret weapon | Virology News | Scoop.it
A new study finds that cows can produce antibodies that neutralize HIV, which may hold clues to a vaccine for humans.
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Long loops in Ig variable regions, right, we know...
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On 'Day Zero,' will Cape Town shut off its water?

On 'Day Zero,' will Cape Town shut off its water? | Virology News | Scoop.it
Cape Town, South Africa could be forced to cut off the majority of its taps in May. Water law expert Buzz Thompson talks about what could happen on "Day Zero."
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So where's the "dry tap" emoji when you need one??
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UCL-AHRI Symposium: Towards HIV and TB elimination in South Africa Tickets, Mon, Feb 12, 2018 at 9:45 AM

UCL-AHRI Symposium: Towards HIV and TB elimination in South Africa Tickets, Mon, Feb 12, 2018 at 9:45 AM | Virology News | Scoop.it
Eventbrite - UCL - Africa Health Research Institute (AHRI) presents UCL-AHRI Symposium: Towards HIV and TB elimination in South Africa - Monday, February 12, 2018 at Roberts Foyer and Sir Ambrose Fleming Lecture Theatre. Find event and ticket information.
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SK Chemicals licenses influenza vaccine technology to Sanofi Pasteur for US$155 mln

SK Chemicals licenses influenza vaccine technology to Sanofi Pasteur for US$155 mln | Virology News | Scoop.it
SK Chemicals Co., a South Korean vaccine maker, said Monday that it has signed a US$155 million deal to license its vaccine technology to Sanofi Pasteur Inc.
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Inovio Pharmaceuticals' Published Universal Flu Vaccine Data Demonstrates Protective Responses Against All Major, Lethal H1N1 Influenza Viruses From the Last 100 Years in Animal Models

Inovio Pharmaceuticals' Published Universal Flu Vaccine Data Demonstrates Protective Responses Against All Major, Lethal H1N1 Influenza Viruses From the Last 100 Years in Animal Models | Virology News | Scoop.it
PLYMOUTH MEETING, Pa., Jan. 22, 2018-- Inovio Pharmaceuticals, Inc. today announced that Inovio’ s synthetic vaccine approach using a collection of synthetic DNA antigens generated broad protective antibod
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Tools that test for life in Arctic could work on Mars

Tools that test for life in Arctic could work on Mars | Virology News | Scoop.it
Researchers wanted to prove that existing technology could detect life on Mars, so they headed to a similar spot here on Earth: the Canadian high Arctic.
Ed Rybicki's insight:
Need to look for viruses
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Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience | Clinical Infectious Diseases | Oxford Academic

Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A           Systematic Review of 10 Years of Real-world Experience | Clinical Infectious Diseases | Oxford Academic | Virology News | Scoop.it
This systematic review assessed the global impact and effectiveness of quadrivalent human
papillomavirus (HPV) vaccination on HPV infection and diseas
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Scientists repurpose HPV vaccine technology to fight eye cancer

Scientists repurpose HPV vaccine technology to fight eye cancer | Virology News | Scoop.it
Uveal melanoma is a rare eye cancer that affects about 1,600 people in the United States. A study by scientists in the Center for Cancer Research and Aura Biosciences, Cambridge, Mass., published December 14, 2017, in Molecular Cancer Therapeutics, provides new hope for the early treatment of uveal melanoma. Read more…
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New type of virus found in the ocean

New type of virus found in the ocean | Virology News | Scoop.it
A type of virus that dominates water samples taken from the world's oceans has long escaped analysis because it has characteristics that standard tests can't detect. However, researchers at MIT and the Albert Einstein Colleg
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It's like dark matter: viruses that evade established methods of detection. BUT we can back-check on collected data to see if they're there...
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Here's what you need to know about the new flu vaccines for over-65s

Two free flu vaccines will improve protection for the over-65s. FluZone High Dose is a high-dose version; Fluad adds an additional ingredient to boost effectiveness. But neither is perfect.
Ed Rybicki's insight:
Free??  Free??  Not here...and as I am rapidly approaching 65, this is of some interest to me!
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Breaking through the HIV vaccine 'logjam'

Breaking through the HIV vaccine 'logjam' | Virology News | Scoop.it
SANTA CRUZ, Calif. –– When biomolecular engineer Phil Berman began his postgraduate work in the 1980s, he had no idea he would spend the rest of his career searching for a way to stop a deadly virus that was then almost entirely known. But around him, as if from nowhere, hundreds of people began to die. He has spent the past three decades looking for an effective vaccine against the AIDS epidemic that would claim more than 20,000 lives in the coastal metropolis alone.
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WHO warns over measles immunisation rates as cases rise 400% across Europe

WHO warns over measles immunisation rates as cases rise 400% across Europe | Virology News | Scoop.it
2017 saw more than 21,000 cases and 35 deaths, with large outbreaks in one in four countries, says World Health Organisation
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The genomic underpinnings of eukaryotic virus taxonomy: creating a sequence-based framework for family-level virus classification

The International Committee on Taxonomy of Viruses (ICTV) classifies viruses into families, genera and species and provides a regulated system for their nomenclature that is universally used in virus descriptions. Virus taxonomic assignments have traditionally been based upon virus phenotypic properties such as host range, virion morphology and replication mechanisms, particularly at family level. However, gene sequence comparisons provide a clearer guide to their evolutionary relationships and provide the only information that may guide the incorporation of viruses detected in environmental (metagenomic) studies that lack any phenotypic data. The current study sought to determine whether the existing virus taxonomy could be reproduced by examination of genetic relationships through the extraction of protein-coding gene signatures and genome organisational features. We found large-scale consistency between genetic relationships and taxonomic assignments for viruses of all genome configurations and genome sizes. The analysis pipeline that we have called ‘Genome Relationships Applied to Virus Taxonomy’ (GRAViTy) was highly effective at reproducing the current assignments of viruses at family level as well as inter-family groupings into orders. Its ability to correctly differentiate assigned viruses from unassigned viruses, and classify them into the correct taxonomic group, was evaluated by threefold cross-validation technique. This predicted family membership of eukaryotic viruses with close to 100% accuracy and specificity potentially enabling the algorithm to predict assignments for the vast corpus of metagenomic sequences consistently with ICTV taxonomy rules. In an evaluation run of GRAViTy, over one half (460/921) of (near)-complete genome sequences from several large published metagenomic eukaryotic virus datasets were assigned to 127 novel family-level groupings. If corroborated by other analysis methods, these would potentially more than double the number of eukaryotic virus families in the ICTV taxonomy. A rapid and objective means to explore metagenomic viral diversity and make informed recommendations for their assignments at each taxonomic layer is essential. GRAViTy provides one means to make rule-based assignments at family and order levels in a manner that preserves the integrity and underlying organisational principles of the current ICTV taxonomy framework. Such methods are increasingly required as the vast virosphere is explored.
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Autoantibody to apolipoprotein A-1 in hepatitis C virus infection: a role in atherosclerosis? 

Autoantibody to apolipoprotein A-1 in hepatitis C virus infection: a role in atherosclerosis?  | Virology News | Scoop.it
Hepatol Int. 2018 Feb 8. doi: 10.1007/s12072-018-9842-5. [Epub ahead of print]
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Non-natural amino acid peptide microarrays to discover Ebola virus glycoprotein ligands

Non-natural amino acid peptide microarrays to discover Ebola virus glycoprotein ligands | Virology News | Scoop.it
We demonstrate a platform to screen a virus pseudotyped with Ebola virus glycoprotein (GP) against a library of peptides that contain non-natural amino acids to develop GP affinity ligands. This system could be used for rapid development of peptide-based antivirals for other emerging or neglected tropical in
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Surveillance reports and disease data on seasonal influenza

Surveillance reports and disease data on seasonal influenza | Virology News | Scoop.it
Surveillance reports and data: Disease data from ECDC Surveillance Atlas, Annual Epidemiological Reports, Surveillance reports.
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Nigerian vaccination campaigns may be threatened by new round of rumours

Nigerian vaccination campaigns may be threatened by new round of rumours | Virology News | Scoop.it

Social media rumours are putting Nigeria's vaccination campaigns at risk.


When a rumour surfaced in 2003 that Nigeria’s polio vaccine was possibly being contaminated with anti-fertility agents a boycott of the vaccine ensued and the country’s polio immunisation campaign was dealt a heavy blow. The boycott lasted for nearly 15 months – from February 2003 to July 2004 – and it had devastating consequences. The polio caseload shot up. And by 2008, Nigeria alone accounted for 86% of all the polio cases on the continent. Since the boycott the country has struggled to be declared polio free.

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Chua Jia Wen's comment, January 26, 11:31 AM
The article explains how fatal consequences resulted when Nigerians decided to mass-boycott a polio vaccination, due to circulating rumours that the government had tainted the polio vaccine with an anti-fertility agent. This unfortunate and unnecessary loss of life reminds us of the importance of communication — all this could have been prevented if the government had properly communicated with the locals, informing them of the main components of the vaccine and assuring them of its safety. What is even more important is the building up of trust between the two parties. Though such an initiative might undoubtedly take time and effort, it would surely be worth it in order to allow the locals and the officials to move together to make the country a better place in solidarity.
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Officials urge calm after chicken sample from Hong Kong vendor tests positive for bird flu virus

Officials urge calm after chicken sample from Hong Kong vendor tests positive for bird flu virus | Virology News | Scoop.it
A chilled chicken sample from China found containing a bird flu virus was sold by a Hong Kong vendor, SCMP reports.
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US University under fire for off-the-grid herpes vaccine experiments

US University under fire for off-the-grid herpes vaccine experiments | Virology News | Scoop.it
Southern Illinois University's medical school has halted all herpes research, one of its most high-profile projects, amid growing controversy over a researcher's unauthorized methods offshore and in the U.S.
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WHO donates 20m doses of yellow fever vaccine

WHO donates 20m doses of yellow fever vaccine | Virology News | Scoop.it
Daily Trust: The World Health Organization (WHO) has promised to donate 20 million doses of vaccines annually towards eradicating yellow fever in the country.
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New Drug Capsule Provides a Week’s Really worth of HIV Medicine in a Single Dose

New Drug Capsule Provides a Week’s Really worth of HIV Medicine in a Single Dose | Virology News | Scoop.it
Researchers at MIT and Brigham and Women’s Clinic have created a capsule that can provide a week’s well worth of HIV drugs in a single dose. The new capsule is developed so that people can get it just after a week, and the drug will launch gradually all over the week. Researchers at MIT and …
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