VIROLOGY LECTURE SERIES
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The Last Days of Smallpox: Tragedy in Birmingham eBook: Mark Pallen: Amazon.ca: Kindle Store

The Last Days of Smallpox: Tragedy in Birmingham eBook: Mark Pallen: Amazon.ca: Kindle Store | VIROLOGY LECTURE SERIES | Scoop.it
The Last Days of Smallpox: Tragedy in Birmingham eBook: Mark Pallen: Amazon.ca: Kindle Store

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Viruses - lots of them - are falling from the sky

Viruses - lots of them - are falling from the sky | VIROLOGY LECTURE SERIES | Scoop.it

An astonishing number of viruses are circulating around the Earth's atmosphere -- and falling from it -- according to new research from scientists in Canada, Spain and the U.S.

 

The study marks the first time scientists have quantified the viruses being swept up from the Earth's surface into the free troposphere, that layer of atmosphere beyond Earth's weather systems but below the stratosphere where jet airplanes fly. The viruses can be carried thousands of kilometers there before being deposited back onto the Earth's surface.

 

"Every day, more than 800 million viruses are deposited per square metre above the planetary boundary layer -- that's 25 viruses for each person in Canada," said University of British Columbia virologist Curtis Suttle, one of the senior authors of a paper in the International Society for Microbial Ecology Journal that outlines the findings.

 

"Roughly 20 years ago we began finding genetically similar viruses occurring in very different environments around the globe," says Suttle. "This preponderance of long-residence viruses traveling the atmosphere likely explains why -- it's quite conceivable to have a virus swept up into the atmosphere on one continent and deposited on another."

 

Bacteria and viruses are swept up in the atmosphere in small particles from soil-dust and sea spray. Suttle and colleagues at the University of Granada and San Diego State University wanted to know how much of that material is carried up above the atmospheric boundary layer above 2,500 to 3,000 meters. At that altitude, particles are subject to long-range transport unlike particles lower in the atmosphere.

 

Using platform sites high in Spain's Sierra Nevada Mountains, the researchers found billions of viruses and tens of millions of bacteria are being deposited per square meter per day. The deposition rates for viruses were nine to 461 times greater than the rates for bacteria.


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Ebola Outbreak Strains Sequenced | The Scientist Magazine®

Ebola Outbreak Strains Sequenced | The Scientist Magazine® | VIROLOGY LECTURE SERIES | Scoop.it
Ninety-nine publicly available genomes could help researchers working to develop diagnostics, vaccines, and therapies. 

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Ed Rybicki's curator insight, August 31, 2014 11:05 AM

99 Ebola genomes, out in cyberspace

99 Ebola genomes, out in cyberspace

And if one Ebola genome

Should accidentally mutate

There'd be...potentially one very frightening Ebola!

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Ebola and ZMapp: What is the 'Secret Serum' That 'Cured' American Doctor Kent Brantly?


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Kenzibit's curator insight, August 5, 2014 3:24 PM

"ZMapp is composed of three 'humanised' monoclonal antibodies manufactured in plants, specifically Nicotiana. It is an optimised cocktail combining the best components of MB-003 and ZMAb.

Kenzibit's curator insight, August 5, 2014 3:25 PM

"ZMapp is composed of three 'humanised' monoclonal antibodies manufactured in plants, specifically Nicotiana. It is an optimised cocktail combining the best components of MB-003 and ZMAb.

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Cytometry Protocols and Video Articles

Cytometry Protocols and Video Articles | VIROLOGY LECTURE SERIES | Scoop.it
Video articles in JoVE about cytometry include "High-throughput Flow Cytometry Cell-based Assay to Detect Antibodies to N-Methyl-D-aspartate Receptor or Dopamine-2 Receptor in Human Serum", "Use of Image Cytometry for Quantification of Pathogenic Fungi in Association with Host Cells", "Measuring Intracellular Ca2+ Changes in Human Sperm using Four Techniques: Conventional Fluorometry, Stopped Flow Fluorometry, Flow Cytometry and Single Cell Imaging", "Quantitative Assessment of Immune Cells in the Injured Spinal Cord Tissue by Flow Cytometry: a Novel Use for a Cell Purification Method", "A Simple and Efficient Method to Detect Nuclear Factor Activation in Human Neutrophils by Flow Cytometry", "Preparation of Myeloid Derived Suppressor Cells (MDSC) from Naive and Pancreatic Tumor-bearing Mice using Flow Cytometry and Automated Magnetic Activated Cell Sorting (AutoMACS)", "Single-cell Analysis of Bacillus subtilis Biofilms Using Fluorescence Microscopy and Flow Cytometry", "Detection of Fluorescent Nanoparticle Interactions with Primary Immune Cell Subpopulations by Flow Cytometry", "Flow Cytometry Analysis of Immune Cells Within Murine Aortas", "Examination of Thymic Positive and Negative Selection by Flow Cytometry".

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Gilbert C FAURE's curator insight, May 23, 2014 6:30 AM

330 results on may 2014

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Dr. Robert Gallo Reflects on 30 Years Since Announcing HIV as the Cause of AIDS - PharmiWeb.com (press release)

Dr. Robert Gallo Reflects on 30 Years Since Announcing HIV as the Cause of AIDS - PharmiWeb.com (press release) | VIROLOGY LECTURE SERIES | Scoop.it
Dr. Robert Gallo Reflects on 30 Years Since Announcing HIV as the Cause of AIDS
PharmiWeb.com (press release)
Today marks 30 years since Robert C.
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Are Bats Spreading Ebola Across Sub-Saharan Africa?

The first cases went unrecognized. Ebola had never been seen in Guinea before, so when people became ill with fever, muscle pain, vomiting, and diarrhea, health workers initially assumed Lassa fever or yellow fever—both endemic in the region—were to blame. No one put the pieces together until late March. By then, the virus had been spreading for months. Now, health workers are struggling to contain the outbreak, which has already killed more than 100 and has affected at least two neighboring countries. At the same time, scientists are combing the forests, and the genome of the virus itself, looking for clues to how this strain—well known in Central Africa—ended up so far west, and whether its spread suggests people in forested areas all across sub-Saharan Africa are at risk.

 

Ebola is not a complete stranger to West Africa. In the mid-1990s, two outbreaks hit chimpanzees in Taï National Park in the Ivory Coast, and one researcher studying the animals was infected. (She survived.) "We expected to find the Taï strain," says Sylvain Baize, a virologist at the Institut Pasteur in Lyon, France, who with his colleagues sequenced some of the first samples of the virus from Guinea. To their surprise, it turned out to be Ebola Zaire, the deadliest of the five known Ebola species.

 

"We have no idea how it's moved from Central Africa to Guinea," says primatologist Christophe Boesch of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. A leading suspect is fruit bats. In Central African rainforests, several species have shown evidence of infection with Ebola without getting sick. And at least one of the species, the little collared fruit bat, Myonycteris torquata, has a range that stretches as far west as Guinea. "We've always been very suspicious of bats," says William Karesh of EcoHealth Alliance in New York City, who studies the interactions among humans, animals, and infectious diseases.


Via Torben Barsballe
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Ed Rybicki's curator insight, April 14, 2014 6:50 AM

Thanks Torben Barsballe!

Brittany Ortiz's curator insight, November 11, 2014 2:56 PM

Something every country should take inconsideration. Its crazy to hear how many Ebola is sprading to different places in Africa. As in the article you can read how maybe they think it has spread to the expansion as it has spread today. Maybe we should start keeping a closer eye on bats.

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Researchers identify a new variant of Ebola virus in Guinea

Researchers identify a new variant of Ebola virus in Guinea | VIROLOGY LECTURE SERIES | Scoop.it
In a new article, researchers have published their initial findings on the characteristics of the Ebola virus discovered in Guinea. Initial virological investigations enabled them to identify Zaire ebolavirus as the pathogen responsible for this epidemic.

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Ten Simple Rules for the Care and Feeding of Scientific Data

Ten Simple Rules for the Care and Feeding of Scientific Data | VIROLOGY LECTURE SERIES | Scoop.it

"Today, most research projects are considered complete when a journal article based on the analysis has been written and published. The trouble is, unlike Galileo's report in Sidereus Nuncius, the amount of real data and data description in modern publications is almost never sufficient to repeat or even statistically verify a study being presented. Worse, researchers wishing to build upon and extend work presented in the literature often have trouble recovering data associated with an article after it has been published. More often than scientists would like to admit, they cannot even recover the data associated with their own published works."


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First comprehensive atlas of human gene activity released | HSPH News | Harvard School of Public Health

First comprehensive atlas of human gene activity released | HSPH News | Harvard School of Public Health | VIROLOGY LECTURE SERIES | Scoop.it

Boston, MA — A large international consortium of researchers has produced the first comprehensive, detailed map of the way genes work across the major cells and tissues of the human body. The findings describe the complex networks that govern gene activity, and the new information could play a crucial role in identifying the genes involved with disease.


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Health News - Researchers solve paradox of virus construction

Health News - Researchers solve paradox of virus construction | VIROLOGY LECTURE SERIES | Scoop.it

Abstract "A new study has solved a long-standing puzzle of how common viruses reproduce themselves during an infection, opening up new possibilities for treating a range of diseases from HIV to the common cold. "


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New dimensions of the virus world discovered through metagenomics

New dimensions of the virus world discovered through metagenomics | VIROLOGY LECTURE SERIES | Scoop.it

Metagenomic analysis of viruses suggests novel patterns of evolution, changes the existing ideas of the composition of the virus world and reveals novel groups of viruses and virus-like agents. The gene composition of the marine DNA virome is dramatically different from that of known bacteriophages. The virome is dominated by rare genes, many of which might be contained within virus-like entities such as gene transfer agents. Analysis of marine metagenomes thought to consist mostly of bacterial genes revealed a variety of sequences homologous to conserved genes of eukaryotic nucleocytoplasmic large DNA viruses, resulting in the discovery of diverse members of previously undersampled groups and suggesting the existence of new classes of virus-like agents. Unexpectedly, metagenomics of marine RNA viruses showed that representatives of only one superfamily of eukaryotic viruses, the picorna-like viruses, dominate the RNA virome.

 

A couple of years old, but a really good introduction.


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Virology 2014 Lecture #4 - Structure of viruses

A discussion of how viruses are constructed, including the principles of icosahedral and helical symmetry, metastability, envelopes, viral glycoproteins, com...
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The virus hunter: How C.J. Peters learned how to bend the rules

The virus hunter: How C.J. Peters learned how to bend the rules | VIROLOGY LECTURE SERIES | Scoop.it
The legendary virologist does not subscribe to the notion that the U.S. can protect itself from infectious disease by focusing only on what’s happening at home. “Fences," he says, "don't keep viruses out.”

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Introduction to Flow Cytometry | AbD Serotec

Introduction to Flow Cytometry | AbD Serotec | VIROLOGY LECTURE SERIES | Scoop.it
Introduction to Flow Cytometry includes chapters on the principles of the flow cytometer & fluorescence, data analysis, common protocols, troubleshooting, further reading

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We'll never find an Ebola vaccine without taking some risks

We'll never find an Ebola vaccine without taking some risks | VIROLOGY LECTURE SERIES | Scoop.it
The current West African ebolavirus outbreak, which has now reached more than 1,000 cases and resulted in more than 800 deaths, is a reminder of the often unpredictable nature of viruses and the difficulties…

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Introduction to Flow Cytometry | AbD Serotec

Introduction to Flow Cytometry | AbD Serotec | VIROLOGY LECTURE SERIES | Scoop.it
Introduction to Flow Cytometry includes chapters on the principles of the flow cytometer & fluorescence, data analysis, common protocols, troubleshooting, further reading

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Virology 2014 lecture #19 - Vaccines - YouTube

Vaccines are our best way to prevent infections. In this lecture we discuss different types of vaccines, such as inactivated, attenuated, and subunit, with i...
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Warnings of 'catastrophic' Chikungunya epidemic; fears it could spread during the World Cup

Warnings of 'catastrophic' Chikungunya epidemic; fears it could spread during the World Cup | VIROLOGY LECTURE SERIES | Scoop.it
A team of French and Brazilian researchers warn that chikungunya virus is poised to invade, and become epidemic in the Americas according to research published ahead of print in the Journal of Virology.

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H5N1: Vietnam sees vaccination rush as measles deaths hit 123

Via Thanh Nien Daily: Vietnam sees vaccination rush as measles deaths hit 123. Excerpt: Adults and children have been flocking the Pasteur Institute in Ho Chi Minh City to seek measles vaccination as the fatalities on infected children have reached...

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Guinea confirms fever is Ebola, has killed up to 59

Guinea confirms fever is Ebola, has killed up to 59 | VIROLOGY LECTURE SERIES | Scoop.it
CONAKRY (Reuters) - Guinea has received confirmation that a mysterious disease that has killed up to 59 people in the West African country, and may have spread to neighboring Sierra Leone, is the hemorrhagic

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Exploiting bacteriophages for human health

Exploiting bacteriophages for human health | VIROLOGY LECTURE SERIES | Scoop.it
This short review is worth reading because it takes a thoughtful and holistic approach to the idea of phage therapy.

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Chris Upton + helpers's curator insight, March 27, 2014 11:51 AM

Via Alan Cann's excellent MicrobiologyBytes site

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HIV cure research – advances and prospects

HIV cure research – advances and prospects | VIROLOGY LECTURE SERIES | Scoop.it
Recent strategies that have been developed in the search for an HIV cure and to improve life quality of people living with HIV.

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Guinea confirms fever is Ebola, has killed up to 59

Guinea confirms fever is Ebola, has killed up to 59 | VIROLOGY LECTURE SERIES | Scoop.it
CONAKRY (Reuters) - Guinea has received confirmation that a mysterious disease that has killed up to 59 people in the West African country, and may have spread to neighboring Sierra Leone, is the hemorrhagic

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