Vaccines, Infectious Diseases, Global Health
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The CDC Is About To Fall Off A Funding Cliff

The CDC Is About To Fall Off A Funding Cliff | Vaccines, Infectious Diseases, Global Health | Scoop.it
The CDC is not the only affected agency. USAID also received $300 million from the same dwindling pot of money, which it used to expand its work in the Middle East and Asia. Those programs may also have to shut down in 2019. These changes would make the world—and the United States—more vulnerable to a pandemic. “We’ll leave the field open to microbes,” says Tom Frieden, a former CDC director who now heads an initiative called Resolve to Save Lives. “The surveillance systems will die, so we won’t know if something happens. The lab networks won’t be built, so if something happens, we won’t know what it is. We can’t be safe if the world isn’t safe. You can’t pull up the drawbridge and expect viruses not to travel.”
Dr. Melvin Sanicas's insight:
“Every time there is an #epidemic, the question that always follows is: Why were we so unprepared?” The CDC is planning to pull back on work that protects the world from #pandemics at a time when #HPAI and novel #pathogens and re-emerging ones threaten to become the next pandemic. 
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The Two Best Ways to Reduce Infant Mortality by Melvin Sanicas

The Two Best Ways to Reduce Infant Mortality by Melvin Sanicas | Vaccines, Infectious Diseases, Global Health | Scoop.it
Preventing early childhood death is one of the main objectives of the global-health community. But while huge investments in health-care infrastructure will no doubt be needed to achieve this goal, the highest returns will most likely come from encouraging maternal immunization and breastfeeding.
Dr. Melvin Sanicas's insight:
One target of the @UN Sustainable Development Goals #SDGs is ending preventable deaths of #newborns & #children under 5 years by 2030. Maternal #immunization & #breastfeeding will help achieve this goal.
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Planning A Trip To Brazil? Do Not Forget Your Yellow Fever Vaccine

Planning A Trip To Brazil? Do Not Forget Your Yellow Fever Vaccine | Vaccines, Infectious Diseases, Global Health | Scoop.it
There is no cure for yellow fever, but there is a vaccine.
Dr. Melvin Sanicas's insight:
#Yellowfever #outbreak in #Brazil prompts US CDC warning to travelers. 10 travelers infected, none of the ten travelers had been vaccinated against yellow fever before they traveled, 4 out of the ten travelers have died.
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Stroke Risk Increases After Dengue Infection

Stroke Risk Increases After Dengue Infection | Vaccines, Infectious Diseases, Global Health | Scoop.it

"Clinicians in dengue-endemic areas should be aware of this association, especially for patients with dengue who have neurologic deficits or for patients with stroke who have unexplained fever," writes Dr. Chia-Hung Kao, Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan, with coauthors. Dengue is a mosquito-borne viral infection that infects at least 100 million people every year around the world, with about 4 billion people at risk of the illness, which includes dengue hemorrhagic fever that can lead to spontaneous bleeding, organ failure and death. It is found in many countries in South and Southeast Asia, Africa, South America, the Caribbean, in the United States and more. The researchers looked at data on 13 787 patients (most between 31 and 60 years of age) with newly diagnosed dengue between 2000 and 2012. They found the incidence of stroke was higher in people with dengue fever (5.33 v. 3.72 per 1000 person-years). The risk of stroke was as high as 2.49 times in the first 2 months of infection with dengue relative to control patients who did not have dengue. "Our findings may help with clinical risk evaluation and may serve as a basis for further investigation of the pathogenesis of dengue-related stroke," conclude the authors.

Dr. Melvin Sanicas's insight:
A new study published in CMAJ (Canadian Medical Association Journal) has found that people with #dengue fever have a higher risk of #stroke, especially in the first 2 months following infection.
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Philippines: Measles Cases Nearly Triple In January

Philippines: Measles Cases Nearly Triple In January | Vaccines, Infectious Diseases, Global Health | Scoop.it
The Philippines Department of Health has reported a near tripling of measles cases during the first month of 2018, compared to the same period in 2017, according to a Measles Disease Surveillance Report recently published. A total of 877 suspect measles cases were reported nationwide from Jan. 1 to Feb. 3, 2018. This is almost …
Dr. Melvin Sanicas's insight:
The #Philippines Department of Health has reported that #measles cases nearly TRIPLED during the first month of 2018, compared to the same period in 2017. A total of 877 suspect measles cases were reported nationwide from Jan. 1 to Feb. 3, 2018,  the same period last year reported only 293 cases. 12 measles related deaths were reported with half coming from Region XI.
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FDA Approves New HIV Treatment For Patients Who Have Limited Treatment Options

FDA Approves New HIV Treatment For Patients Who Have Limited Treatment Options | Vaccines, Infectious Diseases, Global Health | Scoop.it
The FDA approved Trogarzo (ibalizumab-uiyk), a new type of antiretroviral medication for adult patients living with HIV who have tried multiple HIV medications in the past (heavily treatment-experienced) and whose HIV infections cannot be successfully treated with other currently available therapies.
Dr. Melvin Sanicas's insight:
FDA has approved ibalizumab-uiyk (Trogarzo), a new #HIV treatment for patients who have limited treatment options. Unlike other #antiretroviral agents, #Trogarzo binds primarily to the second extracellular domain of the CD4+ T cell receptor, away from major histocompatibility complex II molecule binding sites, potentially prevents HIV from infecting CD4+ immune cells while still preserving normal immunological function.
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Lassa Fever: The Killer Disease With No Vaccine

Lassa Fever: The Killer Disease With No Vaccine | Vaccines, Infectious Diseases, Global Health | Scoop.it
Since the beginning of the year, Nigeria has been gripped by an outbreak of the deadly Lassa fever.
Dr. Melvin Sanicas's insight:
Great piece by @DrCharlieWeller @wellcometrust ‏ in @BBC on #Lassa #fever, a deadly disease with the potential to cause dangerous #epidemics for which no #vaccine currently exists. Lassa virus resides within the multimammate mouse and jumps into people who eat food contaminated by the rodent’s waste. Lassa is on the priority list of @CEPIvaccines
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Disgraced Anti-Vaxxer Andrew Wakefield Aims To Advance His Agenda In Texas Election

Disgraced Anti-Vaxxer Andrew Wakefield Aims To Advance His Agenda In Texas Election | Vaccines, Infectious Diseases, Global Health | Scoop.it
Wakefield sees Houston primary as a new start after his anti-vaccine theories were debunked and medical license revoked
Dr. Melvin Sanicas's insight:
His #theories were DEBUNKED and his #medicallicense was REVOKED, now anti-vaxxer Andrew Wakefield aims to advance his agenda in #Texas #election. He has made a living promoting his discredited theories in the US, thanks to social media. Since the early 2000s, when he arrived, the rate of Texas children exempted from at least one vaccine has shot up by 1900%. 
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Archive on 4: In the Wake of Wakefield

Archive on 4: In the Wake of Wakefield | Vaccines, Infectious Diseases, Global Health | Scoop.it
Adam Rutherford explores the 20-year legacy of a paper linking the MMR vaccine and autism.
Dr. Melvin Sanicas's insight:
FakeNews FakeScience Kill and hurt people. 20 years ago today 26 February 1998, Andrew Wakefield published a paper in @TheLancet falsely suggesting a link between #MMR #measles #mumps #rubella #vaccine and #autism. This was retracted in 2010 and is now considered #fraud @bbchealth
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Growing Outbreak Of Lassa Fever In Nigeria Worries Public Health Officials

Growing Outbreak Of Lassa Fever In Nigeria Worries Public Health Officials | Vaccines, Infectious Diseases, Global Health | Scoop.it
The virus is spread primarily by rats during dry season. The current outbreak in Nigeria has public health officials worried — and eager to find out what's behind it.
Dr. Melvin Sanicas's insight:
#Nigeria is tough on #diseases - it stopped the spread of #Ebola, stopped #guineaworm disease, and nearly eradicated the transmission of #polio but there's been a particularly large #outbreak of #Lassafever in southern provinces.
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A Prophylactic Multivalent Vaccine Against Different Filovirus Species Is Immunogenic & Provides Protection In Non-Human Primates

A Prophylactic Multivalent Vaccine Against Different Filovirus Species Is Immunogenic & Provides Protection In Non-Human Primates | Vaccines, Infectious Diseases, Global Health | Scoop.it
The search for a universal filovirus vaccine that provides protection against multiple filovirus species has been prompted by sporadic but highly lethal outbreaks of Ebolavirus and Marburgvirus infections. A good prophylactic vaccine should be able to provide protection to all known filovirus species and as an upside potentially protect from newly emerging virus strains. We investigated the immunogenicity and protection elicited by multivalent vaccines expressing glycoproteins (GP) from Ebola virus (EBOV), Sudan virus (SUDV), Taï Forest virus (TAFV) and Marburg virus (MARV). Immune responses against filovirus GP have been associated with protection from disease. The GP antigens were expressed by adenovirus serotypes 26 and 35 (Ad26 and Ad35) and modified Vaccinia virus Ankara (MVA) vectors, all selected for their strong immunogenicity and good safety profile. Using fully lethal NHP intramuscular challenge models, we assessed different vaccination regimens for immunogenicity and protection from filovirus disease. Heterologous multivalent Ad26-Ad35 prime-boost vaccination regimens could give full protection against MARV (range 75%-100% protection) and EBOV (range 50% to 100%) challenge, and partial protection (75%) against SUDV challenge. Heterologous multivalent Ad26-MVA prime-boost immunization gave full protection against EBOV challenge in a small cohort study. The use of such multivalent vaccines did not show overt immune interference in comparison with monovalent vaccines. Multivalent vaccines induced GP-specific antibody responses and cellular IFNγ responses to each GP expressed by the vaccine, and cross-reactivity to TAFV GP was detected in a trivalent vaccine expressing GP from EBOV, SUDV and MARV. In the EBOV challenge studies, higher humoral EBOV GP-specific immune responses (p = 0.0004) were associated with survival from EBOV challenge and less so for cellular immune responses (p = 0.0320). These results demonstrate that it is feasible to generate a multivalent filovirus vaccine that can protect against lethal infection by multiple members of the filovirus family.
Dr. Melvin Sanicas's insight:
A new prophylactic #vaccine was #immunogenic and effective against multiple #filoviruses, including #Ebola and #Marburg, in monkeys, according to a study in PLoS One.
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Dengue Vaccination: A More Balanced Approach Is Needed

Dengue Vaccination: A More Balanced Approach Is Needed | Vaccines, Infectious Diseases, Global Health | Scoop.it
Asia Dengue Vaccine Advocacy Group: "Without trivialising the risk of severe disease in seronegative individuals receiving the vaccine, we propose two approaches to dengue vaccination. First, the vaccine can be used safely in highly endemic areas when introduced in a controlled fashion with enhanced surveillance and risk management. For example, physicians can have informed discussions with parents to highlight the fact that the potential benefits of vaccination far outweigh the potential risks for their child on the basis of factors such as the endemicity level where they live and the age of the individual. Second, a reliable laboratory testing method to detect previous exposure could be discussed and implemented. Newer, more rapid, affordable, and accurate diagnostic tests must be developed."
Dr. Melvin Sanicas's insight:
Although each country needs to make its own decisions regarding the use of the #dengue #vaccine, the #publichealth value of the vaccine should not be underestimated. The perfect vaccine does not exist and every new product is likely to have safety risks. Although uncertainties exist, the public health and economic benefits of Dengvaxia far outweigh the potential risks. As the German theologian Meister Eckhart (1260–1328) is credited with saying, “the cost of inaction is far greater than the cost of making a mistake”.
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The CDC Is About To Fall Off A Funding Cliff

The CDC Is About To Fall Off A Funding Cliff | Vaccines, Infectious Diseases, Global Health | Scoop.it
The CDC is not the only affected agency. USAID also received $300 million from the same dwindling pot of money, which it used to expand its work in the Middle East and Asia. Those programs may also have to shut down in 2019. These changes would make the world—and the United States—more vulnerable to a pandemic. “We’ll leave the field open to microbes,” says Tom Frieden, a former CDC director who now heads an initiative called Resolve to Save Lives. “The surveillance systems will die, so we won’t know if something happens. The lab networks won’t be built, so if something happens, we won’t know what it is. We can’t be safe if the world isn’t safe. You can’t pull up the drawbridge and expect viruses not to travel.”
Dr. Melvin Sanicas's insight:
“Every time there is an #epidemic, the question that always follows is: Why were we so unprepared?” The CDC is planning to pull back on work that protects the world from #pandemics at a time when #HPAI and novel #pathogens and re-emerging ones threaten to become the next pandemic. 
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WHO: High Levels Of Antibiotic Resistance Found Worldwide

WHO: High Levels Of Antibiotic Resistance Found Worldwide | Vaccines, Infectious Diseases, Global Health | Scoop.it
WHO’s first release of surveillance data on antibiotic resistance reveals high levels of resistance to a number of serious bacterial infections in both high- and low-income countries.
Dr. Melvin Sanicas's insight:
@WHO released the first #surveillance data on #AntibioticResistance #AMR revealing high levels of resistance to a number of serious #bacterial #infections in both high- and low-income countries.
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World TB Day, 24 March 2018

World TB Day, 24 March 2018 | Vaccines, Infectious Diseases, Global Health | Scoop.it
On World Tuberculosis (TB) Day 2018 (March 24), we find ourselves at a critical moment in the global fight against this curable and preventable infectious disease. We can find, cure, and prevent TB on a global scale, but it will require more work, more science, more determination, and yes, more leaders if we are to end this epidemic. That is why the theme for this year’s TB Day – “Wanted: Leaders for a TB-free world” – is both timely and necessary.
Dr. Melvin Sanicas's insight:
#WorldTBDay2018 We can find, cure, prevent #TB #epidemic on a global scale, but it will require more work, more #science, more determination, & more #Leaders if we are to #EndTB. The theme for this year’s TB Day – “Wanted: Leaders for a TB-free world"
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Common Infections Raise Risk Of Heart Attacks In Same Way As Obesity And High Blood Pressure

Common Infections Raise Risk Of Heart Attacks In Same Way As Obesity And High Blood Pressure | Vaccines, Infectious Diseases, Global Health | Scoop.it
Common infections could double the risk of stroke and significantly increase the chance of a heart attack, new research suggests.
Dr. Melvin Sanicas's insight:
Common #infections may double the #risk of #stroke and significantly increase the chance of a #heartattack, new research suggests. Dangers could be greater than those posed by #obesity and on a par with #hypertension or #diabetes, in increasing risks to the #heart.
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Brazil Yellow Fever Vaccination Efforts Hampered By Rumours, Fear & Social Media

Brazil Yellow Fever Vaccination Efforts Hampered By Rumours, Fear & Social Media | Vaccines, Infectious Diseases, Global Health | Scoop.it
“Good morning!” a loudspeaker blares in the working-class Sao Paulo suburb Jardim Monte Alegre. “We’ve got your yellow fever vaccine, and today we’re going house to house! You better wake up because mosquitoes never sleep!” Twenty health workers pile out of cars. Though they laugh and chat with residents, their mission is deadly serious.
Dr. Melvin Sanicas's insight:
#Misinformation #fakenews about #vaccines is endangering people! In Brazil, wrong information is scaring people away from the #yellowfever vaccination campaign that is trying to reach more than 23 million people. With 237 deaths this season already, officials are concerned the fatality rate will explode if the #virus reaches the slums and the clouds of #mosquitoes waiting there.
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Mandatory Flu Vaccines For Healthcare Workers Reduce Absenteeism

Mandatory Flu Vaccines For Healthcare Workers Reduce Absenteeism | Vaccines, Infectious Diseases, Global Health | Scoop.it

Researchers found that: - Influenza vaccination rates of healthcare personnel at the non-mandatory sites were consistently lower than those at the mandatory sites - Vaccination rates fell at non-mandatory sites during the three years of the study - Vaccinated healthcare workers had a 30 percent reduction in absenteeism compared to non-vaccinated healthcare workers - Absenteeism among healthcare workers was about 6 percent lower at mandatory sites than non-mandatory sites, and the number of days absent also was lower

Dr. Melvin Sanicas's insight:
A multi-institutional study shows that mandatory #flu #vaccines for healthcare workers improve #vaccination rates by as much as 30% and reduce absenteeism during critical periods. #VaccinesWork
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Australia Could Be The First Country To Eradicate Cervical Cancer

Australia Could Be The First Country To Eradicate Cervical Cancer | Vaccines, Infectious Diseases, Global Health | Scoop.it
Free vaccine program in schools leads to big drop in rates although they remain high in the developing world
Dr. Melvin Sanicas's insight:
#Australia, home of Professor Ian Frazer co-inventor of the #HPV #vaccine, could be the FIRST country to eliminate #cervical #cancer! Good on ya, mates! Proof that #VaccinesWork
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How False News Can Spread & How We Can Stop Them

View full lesson: http://ed.ted.com/lessons/how-false-news-can-spread-noah-tavlin In previous decades, most news with global reach came from several majo
Dr. Melvin Sanicas's insight:
#Vaccines cause #autism? NO. False News. Fake News. LIES. Debunked over and over again. How do they spread? We deliberate or unconsciously spread them when we like or share things on the internet before we actually read them or verify its accuracy. It's actually not difficult to VERIFY before we like / share anything. We also indirectly spread them if we don't correct people spreading misinformation. 
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Rare Disease Day 2018

Rare Disease Day 2018 | Vaccines, Infectious Diseases, Global Health | Scoop.it
Find the lastest Rare Disease Day news
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#RareDiseaseDay takes place on the last day of February each year. The main objective of Rare Disease Day is to raise awareness among the general public and decision-makers about rare diseases and their impact on patients' lives. 
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Dengvaxia Scare: Turning A Serious Health Issue To A Political Witch-Hunt

Dengvaxia Scare: Turning A Serious Health Issue To A Political Witch-Hunt | Vaccines, Infectious Diseases, Global Health | Scoop.it
The Vaccine Confidence Project is an academic research group based at the London School of Hygiene & Tropical Medicine.
Dr. Melvin Sanicas's insight:
Here’s what an external academic research group based at the London School of Hygiene & Tropical Medicine and funded by the Bill & Melinda Gates Foundation and the World Health Organization thinks about the #Dengvaxia issue in the #Philippines.
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Oregon Children Missing Vaccines Will Be Sent Home From School Tomorrow

Oregon Children Missing Vaccines Will Be Sent Home From School Tomorrow | Vaccines, Infectious Diseases, Global Health | Scoop.it
As of 2016, about two-thirds of two-year-olds in Oregon were up-to-date on their vaccines.
Dr. Melvin Sanicas's insight:
Oregon children who aren’t up-to-date on their #vaccines will be sent home from school starting tomorrow. Required vaccinations include those for #whoopingcough, #polio, #chickenpox and #measles. Oregon is looking out for all Oregonians, standing up for community values and #publichealth.
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Brazil Battles Yellow Fever — And A ‘Dangerous’ Anti-Vaccination Campaign

Brazil Battles Yellow Fever — And A ‘Dangerous’ Anti-Vaccination Campaign | Vaccines, Infectious Diseases, Global Health | Scoop.it

A new report from the Pan American Health Organization (PAHO) documents yellow fever cases in animals and humans from January 2016 through January 2018 in South America, showing the most cases reported in decades. Seven countries—Bolivia, Brazil, Colombia, Ecuador, French Guiana, Peru, and Suriname—reported yellow fever activity in the last 2 years, with Brazil hosting the majority of cases since that country began experiencing the current outbreak at the end of 2016. Only Brazil and Peru have reported cases in 2018. As reported last week, Brazil is falling short on its goal to vaccinate 20.5 million people most at risk for yellow fever. The residents of Sao Paulo and Rio de Janeiro states have been targeted in an ongoing campaign intended to prevent transmission in Brazil's most populated cities. As of Feb 15, only 3.95 million people have been vaccinated, the vast majority (3.6 million) with fractional doses of the standard vaccine. One reason for the failure of vaccine uptake may be ongoing anti-vaccine activity in Brazil. The Washington Post reports that many Brazilians, relying on viral posts on Facebook and other social media sites, believe the yellow fever vaccine is dangerous—even deadly. "We're seeing fake news about yellow fever spread at an alarming rate on social networks," said Igor Sacramento, a health communication researcher at Fiocruz, a large research and development center in Rio de Janeiro. According to Brazil's Health Ministry, five people died last year because of complications from the vaccine. For the vast majority, however, the yellow fever vaccine causes no side effects, or very mild ones. The standard yellow fever vaccine dose offers lifelong protection within 30 days of inoculation. Factional dosing is used to stretch yellow fever vaccine supplies and it may offer immunity for a minimum of 1 year.

Dr. Melvin Sanicas's insight:
#SouthAmerica records most #yellowfever cases in decades. One reason for the failure of #vaccine uptake is the ongoing #antivaccine activity in #Brazil. Many Brazilians, relying on viral posts on Facebook and other social media sites, believe the yellow fever vaccine is dangerous—even deadly.
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ScientificAnimations's comment, February 20, 7:53 AM
Infectious Disease Deaths in US: What’s changed in 100 Years? - http://sco.lt/4wlk0H
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Vaccines Prevent Not Just Disease, But Also Poverty

Vaccines Prevent Not Just Disease, But Also Poverty | Vaccines, Infectious Diseases, Global Health | Scoop.it

The Harvard study, co-authored by Gavi, the Vaccine Alliance and a wide range of partners, modelled the health and economic impact of vaccines for ten diseases in 41 developing countries. As well as the economic impact, the study also estimated that vaccines administered between 2016 and 2030 would prevent 36 million deaths.

Dr. Melvin Sanicas's insight:
New #study shows that #immunization in world’s #poorest countries is set to save millions from one of the primary causes of extreme #poverty: #health expenses #VaccinesWork #GAVI
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India Eliminating Trachoma & Other Global Health Successes In 2017

India Eliminating Trachoma & Other Global Health Successes In 2017 | Vaccines, Infectious Diseases, Global Health | Scoop.it
My guest on today’s podcast says that while there were many successes in human development in 2017, arguably, the most significant achievements of the last 12 months were in global health. Public health physician and a vaccinologist, Dr Melvin Sanicas wrote in an article in Project Syndicate that he counted at least 18 unique successes in …
Dr. Melvin Sanicas's insight:
Sharing my #OutbreakNewsToday interview with @bactiman63 on #India eliminating #trachoma & other #globalhealth big wins in 2017 including #NTDs #vaccines #typhoid #shingles #endpolio #Zika #ZeroLeprosy @ProSyn
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