Systemic Mastocytosis, Tinnitus etc
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White matter abnormalities are also repeatedly present in patients with systemic mast cell activation syndrome

White matter abnormalities are also repeatedly present in patients with systemic mast cell activation syndrome | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Correspondence...
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Life, Not Love: An Introduction to Mast Cell Activation Syndrome

Life, Not Love: An Introduction to Mast Cell Activation Syndrome | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Today I'm sharing a bit about a chronic illness that affects how we live and how we travel. Join us as we learn about Mast Cell Activation Syndrome.
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This Is What A Mast Cell Activation Syndrome Is Like –

This Is What A Mast Cell Activation Syndrome Is Like – | Systemic Mastocytosis, Tinnitus etc | Scoop.it
My stomach drops. Perspiration accumulates on the palms of my hands as the room gets hotter. The impending doom initiates a fight or flight response similar to waiting at the top of a roller coaster, suspended in mid-air and anticipating the thrill of the impending descent.
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Anaphylaxis: emergency management for health professionals | Australian Prescriber

Anaphylaxis: emergency management for health professionals | Australian Prescriber | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Any acute onset of hypotension or bronchospasm or upper airway obstruction where anaphylaxis is considered possible,...
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One suggestion to this: when patient is lying down, elevate legs so blood flow is to the heart.
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Leukemic-phase progression of aleukemic mast cell leukemia

Leukemic-phase progression of aleukemic mast cell leukemia | Systemic Mastocytosis, Tinnitus etc | Scoop.it
![Figure][1]</img> A 35-year-old woman who presented with recurrent episodes of flushing, headache, palpitations, and elevated serum tryptase (81.7 ng/mL) was treated with fexofenadine and imatinib and diagnosed with the aleukemic variant of mast cell leukemia (MCL), defined as a high percentage ...
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Mast Cell Disease Classification: What Is The Difference Between Mastocytosis & MCAS?

Mast Cell Disease Classification: What Is The Difference Between Mastocytosis & MCAS? | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Although mastocytosis and MCAS are variants of the same disease (MCD), there are some interesting differences between these two particular types of mast cell disorders.Here’s a breakdown of the main ones, which are important to understand because knowing what to look for in each can determine the...
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Guidelines for the management of osteoporosis and fragility fractures

Guidelines for the management of osteoporosis and fragility fractures | Systemic Mastocytosis, Tinnitus etc | Scoop.it
The purpose of this document, a result of the harmonisation and revision of Guidelines published separately by the SIMFER, SIOMMMS/SIR, and SIOT associations, is to provide practical indications...
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Data From a Phase I Study of a Drug to Treat Systemic Mastocytosis Has Been Released

Data From a Phase I Study of a Drug to Treat Systemic Mastocytosis Has Been Released | Systemic Mastocytosis, Tinnitus etc | Scoop.it
The company Blueprint Medicines Corporation has released an update on their Phase 1 trial of the experimental drug avapritinib for the treatment of systemic mastocytosis.
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European Medicines Agency - Find medicine - Masipro

European Union agency responsible for the protection of public and animal health through the scientific evaluation and supervision of medicines.
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The Possible Role of Gene Variant Coding Nonfunctional Toll-Like Receptor 2 in the Pathogenesis of Mastocytosis - Abstract - International Archives of Allergy and Immunology 2018, Vol. 177, No. 1 -...

The Possible Role of Gene Variant Coding Nonfunctional Toll-Like Receptor 2 in the Pathogenesis of Mastocytosis - Abstract - International Archives of Allergy and Immunology 2018, Vol. 177, No. 1 -... | Systemic Mastocytosis, Tinnitus etc | Scoop.it
<b><i>Background:</i></b> Data on the genetic predisposition to mastocytosis are scarce.The aim of this work was to study the association of single nucleotide polymorphisms of Toll-like receptor (<i>...
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New Drug Shows Promise for Rare Blood Cancers

New Drug Shows Promise for Rare Blood Cancers | Systemic Mastocytosis, Tinnitus etc | Scoop.it
An experimental drug called midostaurin may reverse organ damage in people with certain rare, fatal blood cancers, an early clinical trial finds.
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Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options

Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Mast cell activation disease comprises disorders characterized by accumulation of genetically altered mast cells and/or abnormal release of these cells' mediators, affecting functions in potentially every organ system, often without causing abnormalities ...
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Alexa Kauffman | Ms Health and Fitness

Alexa Kauffman | Ms Health and Fitness | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Who will take home twenty grand and be featured in Muscle and Fitness Hers?
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Are Most Spoonies Suffering from MCAD? –

Are Most Spoonies Suffering from MCAD? – | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Are Mast Cell Activation Disorders (MCAD) being missed and heavily under-diagnosed in a large portion of patients with chronic illness? Could these easily misunderstood conditions be the cause of the rapid fluctuations in your health?
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Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers

Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Anaphylaxis is the most serious of all allergic reactions and can be fatal. The diagnosis is frequently delayed, and misdiagnosis often occurs with asthma or urticaria. Biomarkers such as tryptase are not routinely checked, and appropriate treatment with ...
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List of Ways Anxiety Shows Up Because of Rare Disease

List of Ways Anxiety Shows Up Because of Rare Disease | Systemic Mastocytosis, Tinnitus etc | Scoop.it
The Mighty asks its rare disease community to describe how anxiety affects them on a daily basis....
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MCAD Q&A: Mast Cell Disease vs. Histamine Intolerance?

MCAD Q&A: Mast Cell Disease vs. Histamine Intolerance? | Systemic Mastocytosis, Tinnitus etc | Scoop.it
I had a reader ask me recently what the difference is between MCAS, mastocytosis and histamine intolerance and I’ve been wanting to write a post about this topic for awhile. I did some research and found a really great explanation from one of the experts in this area, Dr.
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Systemic Mastocytosis and stem cell treatment for myeloproliferative neoplasm

Systemic Mastocytosis and stem cell treatment for myeloproliferative neoplasm | Systemic Mastocytosis, Tinnitus etc | Scoop.it
What is Systemic Mastocytosis? Systemic Mastocytosis, also known as Systemic Mast Cell Disease, is a myeloproliferative neoplasm.It is characterised by the abnormal accumulation of mast cells in…...
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Are Vaccines Linked to Increase in Mast Cell Disease and Allergies?

Are Vaccines Linked to Increase in Mast Cell Disease and Allergies? | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Do you or does someone you know have severe symptoms of itching, rashes, flushing, stomach or other body pain, frequent diarrhea, nausea, fatigue, brain fog,...
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The search for the origin of mast cells

The search for the origin of mast cells | Systemic Mastocytosis, Tinnitus etc | Scoop.it
A team of researchers has proven that not all of the immune system's important mast cells are produced in bone marrow, as was previously thought. Scientists found embryonic mast cells in mice with functions that are likely to be different than the mast cells found in adults.
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Anesthetic management of patients with systemic mastocytosis

Anesthetic management of patients with systemic mastocytosis | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Systemic mastocytosis is a rare disease of mast cell proliferation in multiple organs
and carries a risk of anaphylactic reaction by degranulation induced by physical and
psychological stimuli, alcohol, elevated temperature, and drugs known to release histamine
[1, 2].
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Ranitidine Syrup: Liquid Zantac to Stop Heartburn

Ranitidine Syrup: Liquid Zantac to Stop Heartburn | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Picture this: You're enjoying a lovely night out with friends at one of your favorite restaurants. You're indulging in their delicious food and having a wonderful time. Then, an hour later, you suddenly start to feel sick.
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What Is A Mast Cell?

Specifically, it is a type of granulocyte derived from the myeloid stem cell that part immune and neuroimmune systems contains many granules rich in histamin...
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This Week's Biotech IPOs

This Week's Biotech IPOs | Systemic Mastocytosis, Tinnitus etc | Scoop.it
The IPO activity in the U.S. pharma/biotech sector had a strong showing last quarter (Q2) with 24 listings compared to 13 in the year-ago period. There has not been a single biotech IPO for the month of July so far.
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Symptoms and Triggers of Mast Cell Activation - TMS - The Mastocytosis Society :TMS – The Mastocytosis Society

Symptoms and Triggers of Mast Cell Activation - TMS - The Mastocytosis Society :TMS – The Mastocytosis Society | Systemic Mastocytosis, Tinnitus etc | Scoop.it
Mast Cell Activation and Triggers Mast cells can be activated to release mediators by multiple triggers. Possible triggers of mediator release are shown below in Figure 1. Please note that any patient with a mast cell disorder can potentially react to any trigger, and triggers can change over the...
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