Therapeutic cancer vaccines
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Top 10 Immuno-Oncology Collaborations | The Lists | GEN

Top 10 Immuno-Oncology Collaborations | The Lists | GEN | Therapeutic cancer vaccines | Scoop.it
Immuno-oncology collaborations numbers keep climbing.
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T cell revival correlates with lung cancer response to PD-1 immunotherapy

T cell revival correlates with lung cancer response to PD-1 immunotherapy | Therapeutic cancer vaccines | Scoop.it
In lung cancer patients who were taking immunotherapy drugs targeting the PD-1 pathway, testing for CD8 T cell activation in their blood partially predicted whether their tumors would shrink.
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On-treatment immune analysis predicts response to melanoma immunotherapy

The leading news and search platform for precision medicine and medical diagnostics. From biomarkers to genetic testing and molecular diagnostics, a comprehensive review of up-to-date information required by researchers and physicians.
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IO Landscape visualization - Beacon Intelligence

IO Landscape visualization - Beacon Intelligence | Therapeutic cancer vaccines | Scoop.it
Beacon Intelligence | Hanson Wade
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A spectacular visualization of the IO network • Currently there are 746 IO combination clinical trials (correct as of Aug 11th 2016) • These involve 47 different ICIs • 295 organizations are involved in these trials
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Advaxis’ AXAL Receives Fast Track Designation by the FDA as Adjuvant Therapy for High-Risk Locally Advanced Cervical Cancer Patients

Advaxis’ AXAL Receives Fast Track Designation by the FDA as Adjuvant Therapy for High-Risk Locally Advanced Cervical Cancer Patients | Therapeutic cancer vaccines | Scoop.it
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Merck, Moderna tie up in $200M deal to develop mRNA-based ‘personalized’ cancer vaccines | FierceBiotech

Merck, Moderna tie up in $200M deal to develop mRNA-based ‘personalized’ cancer vaccines | FierceBiotech | Therapeutic cancer vaccines | Scoop.it
Merck will pay $200 million upfront to Moderna, which the company will use to lead all R&D efforts through proof of concept and to build out a suburban Boston manufacturing facility. The program will focus on several types of cancer and include combinations with Merck’s Keytruda (pembrolizumab).
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Phase II Lung Cancer Clinical Trial Could Bring Another Immunotherapy Option to Mesothelioma Patients

Phase II Lung Cancer Clinical Trial Could Bring Another Immunotherapy Option to Mesothelioma Patients | Therapeutic cancer vaccines | Scoop.it
Using a special type of cell known as a dendritic cell that is a key regulator in the immune system, a U.S. company has created an immunotherapy treatment for lung cancer that is personalized to the patient’s specific tumor characteristics.
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Immune Evasion Pathways and the Design of Dendritic Cell-based Cancer Vaccines - Brent A Hanks - Discovery Medicine

Immune Evasion Pathways and the Design of Dendritic Cell-based Cancer Vaccines - Brent A Hanks - Discovery Medicine | Therapeutic cancer vaccines | Scoop.it
Emerging data is suggesting that the process of dendritic cell (DC) tolerization is an important step in tumorigenesis. Our understanding of the networks within the tumor microenvironment that functionally tolerize DC function is evolving while methods for genetically manipulating DC .
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Boehringer's VC fund leads Series A investment in cancer vaccine startup | FierceBiotech

Boehringer's VC fund leads Series A investment in cancer vaccine startup | FierceBiotech | Therapeutic cancer vaccines | Scoop.it
Boehringer Ingelheim Venture Fund has led a Series A investment intended to propel peptide-based cancer vaccine startup Amal Therapeutics toward clinical trials. The startup landed the investment on the strength of technology it thinks can address some of the historic failings of cancer vaccines.
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With $55M, Neon Wants To Make the Cancer Vaccine "Problem" Personal | Xconomy

With $55M, Neon Wants To Make the Cancer Vaccine "Problem" Personal | Xconomy | Therapeutic cancer vaccines | Scoop.it
One year ago, in a paper in the journal Oncoimmunology, three cancer researchers wrote this: "After many years of best efforts and countless dollars, but u
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Cancer Immunotherapy Market to Reach $9 Billion Across the World by 2022

Cancer Immunotherapy Market to Reach $9 Billion Across the World by 2022 | Therapeutic cancer vaccines | Scoop.it
PUNE, India, November 5, 2015 /PRNewswire/ -- Cancer Immunotherapy Market to Reach $9 Billion Across the World by 2022.
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Celldex Therapeutics, Inc. (NASDAQ:CLDX) Cancels Phase III Trials of Cancer Vaccine

Celldex Therapeutics, Inc. (NASDAQ:CLDX) Cancels Phase III Trials of Cancer Vaccine | Therapeutic cancer vaccines | Scoop.it
Celldex Therapeutics, Inc. (NASDAQ:CLDX) has contributed to medical science field in a number of ways over the last many years, but things have changed now. Reports claim that it has stopped Phase …
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Scientists Just Made a Breakthrough That Could Change the Face of Cancer Treatment

Scientists Just Made a Breakthrough That Could Change the Face of Cancer Treatment | Therapeutic cancer vaccines | Scoop.it
Scientists at the University College London (UCL) have made a major breakthrough that may further cement so-called immunotherapies' status as the most promising advance in cancer treatments in years. The researchers published their findings in the journal Science.
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Top 15 Immuno-Oncology Collaborations | The Lists | GEN

Top 15 Immuno-Oncology Collaborations | The Lists | GEN | Therapeutic cancer vaccines | Scoop.it
The top 15 immuno-oncology collaborations' total value of all 15 ranked collaborations is approximately $30 billion.
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Cancer vaccines market will triple to $7.5B by 2022, report says | FiercePharma

Cancer vaccines market will triple to $7.5B by 2022, report says | FiercePharma | Therapeutic cancer vaccines | Scoop.it
Though cancer vaccines have experienced disappointing clinical performance in recent years, their global market as a crucial tool in immunotherapy will grow from $2.5 billion in 2015 to $7.5 billion by 2022, a new report predicts.
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Diagnostic Biomarkers for Cancer Immunotherapy – Moving Beyond PD-L1 / DeciBio | Insights

Diagnostic Biomarkers for Cancer Immunotherapy – Moving Beyond PD-L1 / DeciBio | Insights | Therapeutic cancer vaccines | Scoop.it
Decibio offers expert Mdx market reports, analysis of Life Sciences research tools market trends, NGS market growth reports, and DME market outlook reports.
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Roche drops Partnership for Hepatitis Immunotherapy

Roche drops Partnership for Hepatitis Immunotherapy | Therapeutic cancer vaccines | Scoop.it
The European Biotech News Website
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Moderna Gets $200M More, Deepens Merck Ties With New Cancer Pact | Xconomy

Moderna Gets $200M More, Deepens Merck Ties With New Cancer Pact | Xconomy | Therapeutic cancer vaccines | Scoop.it
Moderna Therapeutics still hasn’t produced data in humans supporting its technology, which is meant to turn our bodies into little drugmaking factories. Bu
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Caladrius Licenses Cell Therapy Technology to AiVita Biomedical | GEN News Highlights | GEN

Caladrius Licenses Cell Therapy Technology to AiVita Biomedical | GEN News Highlights | GEN | Therapeutic cancer vaccines | Scoop.it
Deal covering tumor cell/dendritic cell technology is second licensing agreement between the companies since February
Laurent LEVY's insight:
Caladrius—which changed its name last year from NeoStem—has also refocused its clinical development efforts on CLBS03, a Phase II T regulatory cell therapy candidate for type 1 diabetes
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FDA approves First ever antibody to target Cancer PD-L1

FDA approves First ever antibody to target Cancer PD-L1 | Therapeutic cancer vaccines | Scoop.it
The European Biotech News Website
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Argos Therapeutics Announces Initiation of a Phase 2 Clinical Trial of AGS-003 for the Treatment of Non-small Cell Lung Cancer in Combination with Standard-of-Care Chemotherapy (NASDAQ:ARGS)

Argos Therapeutics Announces Initiation of a Phase 2 Clinical Trial of AGS-003 for the Treatment of Non-small Cell Lung Cancer in Combination with Standard-of-Care Chemotherapy (NASDAQ:ARGS) | Therapeutic cancer vaccines | Scoop.it
DURHAM, N.C., March 23, 2016 (GLOBE NEWSWIRE) -- Argos Therapeutics, Inc. (Nasdaq:ARGS) (
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AGS-003 is an individualized immunotherapy designed to induce a memory T-cell response specific to each patient's cancer, including the unique tumor mutations (or neoantigens). It is produced using a small sample of RNA from a patient's own tumor, and dendritic cells derived from a cell collection procedure from the patient
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Vaxon completes enrolment in Phase IIb trial of Vx-001 in NSCLC

Vaxon completes enrolment in Phase IIb trial of Vx-001 in NSCLC | Therapeutic cancer vaccines | Scoop.it
Vx-001 is a therapeutic cancer vaccine based on proprietary antigens known as optimised cryptic tumou
Laurent LEVY's insight:
A total of 220 patients with metastatic NSCLC have now been enrolled in this Phase IIb trial across 70 European trial centres. The primary endpoint is to assess the benefit of Vx-001 versus placebo on overall survival. Final trial results are expected in the fourth quarter of 2016.
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BMS' Opdivo gets two new indications in Europe - PMLiVE

BMS' Opdivo gets two new indications in Europe - PMLiVE | Therapeutic cancer vaccines | Scoop.it
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The new indication in non-small cell lung cancer (NSCLC) is for patients with squamous cell-derived tumours who have previously been treated for the disease with chemotherapy - adding to its existing second-line use in non-squamous NSCLC and for newly-diagnosed and previously-treated melanoma
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Principles and Application of Immunotherapy for Cancer: Advanced NSCLC

In this webcast from the 2015 CCO ACCC live meeting series on the Principles and Application of Immunotherapy for Cancer, Heather Wakelee, MD, provide
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Argos Nabs Up to $60M to Continue Kidney Cancer Treatment Work | Xconomy

Argos Nabs Up to $60M to Continue Kidney Cancer Treatment Work | Xconomy | Therapeutic cancer vaccines | Scoop.it
Argos Therapeutics reached an investment deal that provides up to $60 million in financing as the drug developer plows ahead on late-stage clinical trial w
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