The laboratory for Plant Metabolism and Metabolic Networks
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Grape Berry Acclimation to Excessive Solar Irradiance Leads to Repartitioning between Major Flavonoid Groups - Journal of Agricultural and Food Chemistry (ACS Publications)

Grape Berry Acclimation to Excessive Solar Irradiance Leads to Repartitioning between Major Flavonoid Groups - Journal of Agricultural and Food Chemistry (ACS Publications) | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Grape Berry Acclimation to Excessive Solar Irradiance Leads to Repartitioning between Major Flavonoid Groups
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Frontiers | Sunlight modulates fruit metabolic profile and shapes the spatial pattern of compound accumulation within the grape cluster | Crop Science and Horticulture

Frontiers | Sunlight modulates fruit metabolic profile and shapes the spatial pattern of compound accumulation within the grape cluster | Crop Science and Horticulture | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Vineyards are characterized by their large spatial variability of solar irradiance (SI) and temperature, known to effectively modulate grape metabolism. To explore the role of sunlight in shaping fruit composition and cluster uniformity, we studied the spatial pattern of incoming irradiance, fruit temperature and metabolic profile within individual grape clusters under three levels of sunlight exposure. The experiment was conducted in a vineyard of Cabernet Sauvignon cv. located in the Negev Highlands, Israel, where excess SI and midday temperatures are known to degrade grape quality. Filtering SI lowered the surface temperature of exposed fruits and increased the uniformity of irradiance and temperature in the cluster zone. SI affected the overall levels and patterns of accumulation of sugars, organic acids, amino acids and phenylpropanoids, across the grape cluster. Increased exposure to sunlight was associated with lower accumulation levels of malate, aspartate, and maleate but with higher levels of valine, leucine, and serine, in addition to the stress-related proline and GABA. Flavan-3-ols metabolites showed a negative response to SI, whereas flavonols were highly induced. The overall levels of anthocyanins decreased with increased sunlight exposure; however, a hierarchical cluster analysis revealed that the members of this family were grouped into three distinct accumulation patterns, with malvidin anthocyanins and cyanidin-glucoside showing contrasting trends. The flavonol-glucosides, quercetin and kaempferol, exhibited a logarithmic response to SI, leading to improved cluster uniformity under high-light conditions. Comparing the within-cluster variability of metabolite accumulation highlighted the stability of sugars, flavan-3-ols, and cinnamic acid metabolites to SI, in contrast to the plasticity of flavonols. A correlation-based network analysis revealed that extended exposure to SI modified metabolic coordination, increasing the number of negative correlations between metabolites in both pulp and skin. This integrated study of micrometeorology and metabolomics provided insights into the grape-cluster pattern of accumulation of 70 primary and secondary metabolites as a function of spatial variations in SI. Studying compound-specific responses against an extended gradient of quantified conditions improved our knowledge regarding the modulation of berry metabolism by SI, with the aim of using sunlight regulation to accurately modulate fruit composition in warm and arid/semi-arid regions.
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Effects of Parental Temperature and Nitrate on Seed Performance are Reflected by Partly Overlapping Genetic and Metabolic Pathways.

Effects of Parental Temperature and Nitrate on Seed Performance are Reflected by Partly Overlapping Genetic and Metabolic Pathways. | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Seed performance is affected by the seed maturation environment and previously, we have shown that temperature, nitrate and light intensity were the most influential environmental factors affecting seed performance. Seeds developed in these environments were selected to assess the underlying metabolic pathways, using a combination of transcriptomics and metabolomics. These analyses revealed that the effects of the temperature and nitrate parental environments were reflected by partly overlapping genetic and metabolic networks, as indicated by similar changes in metabolites and transcripts expression levels. Nitrogen-metabolism related metabolites (asparagine, GABA and allantoin) were significantly decreased in both low temperature (15°C) and low nitrate (N0) maturation environments. Correspondingly, nitrogen-metabolism genes (ALLANTOINASE, NITRATE REDUCTASE 1, NITRITE REDUCTASE 1 and NITRILASE 4) were differentially regulated in the low temperature and nitrate maturation environments, as compared with control conditions. High light intensity during seed maturation increased galactinol content, and displayed a high correlation with seed longevity. Low light had a genotype-specific effect on cell surface encoding genes in the DELAY OF GERMINATION 6-Near Isogenic Line (NILDOG6). Overall, the integration of phenotypes, metabolites and transcripts led to new insights in the regulation of seed performance.
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Frontiers | Amino Acids of the Glutamate Family: Functions beyond Primary Metabolism

Frontiers | Amino Acids of the Glutamate Family: Functions beyond Primary Metabolism | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
The life of proteins starts and ends as amino acids. In addition to the primary function as protein building blocks, amino acids serve multiple other purposes to make a plant's life worth living
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Si agli OGM contro la poverta'. Expo parli di economia e fame

Si agli OGM contro la poverta'. Expo parli di economia e fame | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it

Problems are generated NOT by the technologies, but by the poor land management

Aaron Fait's insight:

Nobel prize Amartya Sen encourages for a rationalised and logic discourse on GM crops

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Coffea arabica yields decline in Tanzania due to climate change: Global implications

Coffea arabica yields decline in Tanzania due to climate change: Global implications | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Aaron Fait's insight:

"One more cup of coffee for the road
One more cup of coffee 'fore I go.
To the valley below", but will we afford it in a hundred years?

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http://www.vitevinoqualita.it/vq-media-partner-di-ivas2015/

http://www.vitevinoqualita.it/vq-media-partner-di-ivas2015/ | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Aaron Fait's insight:

VQ Vite, Vino & Qualità will be media partner of IVAS2015,  In Vino Analytica Scientia Symposium, which will take place in Trentino Alto Adige, Italy. Inside the April issue the interview on "making the desert bloom" on desert viticulture. 

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Human fear of spiders draws scientific focus

Human fear of spiders draws scientific focus | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
A fear of spiders, arachnophobia, is in our DNA. You don't learn to freeze at the site of these creatures; you're born with the fear. Even the sight of hypodermic needles and houseflies does not trigger a similar response. Scientists pin that fear on survival instinct. The theory goes like this: Humans ...
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my mom's fear of spiders is ...an evolutionary survival kit

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Water for Life - Zuckerberg Institute for Water Research - YouTube

The Zuckerberg Institute for Water Research (ZIWR) was founded in January 2002 within the Jacob Blaustein Institutes for Desert Research, at the Sede Boqer C...
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Genetic Modification -- science vs belief - YouTube

Genetic Modification -- science vs belief - YouTube | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
00 -- "Scientists Warn of Genetically Modified Organisms ( GMOs ) Dire Consequences" (YouTube) 1:28 -- "How GMO foods alter organ function and pose a very re...
Aaron Fait's insight:

"Hadfield takes a rational approach for 17 minutes to deconstruct anti-GMO arguments made by advocates, citing science and rational thinking. Hadfield breaks down the popular blog post 10 Scientific Studies Proving GMOs Can Be Harmful To Human Health‘ that has seen itself gone viral in the past. But at the end of the day, most of these so-called “studies” are either inaccurate or not really about GMOs, something GLP writer Layla Katiraee wrote about in the past. 

In conclusion, despite the title of the article, none of these studies proves or even persuasively suggests that GMOs can be harmful to human health. The majority are either obviously flawed or are not scientific studies." 

http://geneticliteracyproject.org/2015/02/23/video-are-gm-foods-dangerous-renowned-science-reporter-geologist-takes-on-anti-gmo-fundamentalists/

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Princeton University - Tiny termites can hold back deserts by creating oases of plant life

Princeton University - Tiny termites can hold back deserts by creating oases of plant life | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
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Size matters in the battle to adapt to diverse environments and avoid extinction

Size matters in the battle to adapt to diverse environments and avoid extinction | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
A new University of Toronto study may force scientists to rethink what is behind the mass extinction of amphibians occurring worldwide in the face of climate change, disease and habitat loss.
Aaron Fait's insight:

In danger of extinction, size diversification might be of advantage... hurrah Al Pacino!

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The Annual Meeting of the Israeli Society of Plant Sciences

The Annual Meeting of the Israeli Society of Plant Sciences | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
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Frontiers | Data Reduction Approaches for Dissecting Transcriptional Effects on Metabolism | Plant Science

The availability of high-throughput data from transcriptomics and metabolomics technologies provides the opportunity to characterizethe transcriptional effects on metabolism. Here we propose and evaluate two computational approaches rooted in data reduction techniques to identify and categorize transcriptional effects on metabolism by combining data on gene expression and metabolite levels. The approaches determine the partial correlation between two metabolite data profiles upon control of given principal components extracted from transcriptomics data profiles. Therefore, they allow us to investigate both data types with all features simultaneously without doing preselection of genes. The proposed approaches allow us to categorize the relation between pairs of metabolites as being under transcriptional or post-transcriptional regulation. The resulting classification is compared to existing literature and accumulated evidence about regulatory mechanism of reactions and pathways in the cases of \emph{Escherichia coli}, \emph{Saccharomycies cerevisiae}, and \emph{Arabidopsis thaliana}.
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Frontiers | Anastatica hierochuntica, an Arabidopsis Desert Relative, Is Tolerant to Multiple Abiotic Stresses and Exhibits Species-Specific and Common Stress Tolerance Strategies with Its Halophyt...

Frontiers | Anastatica hierochuntica, an Arabidopsis Desert Relative, Is Tolerant to Multiple Abiotic Stresses and Exhibits Species-Specific and Common Stress Tolerance Strategies with Its Halophyt... | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
The search for novel stress tolerance determinants has led to increasing interest in plants native to extreme environments – so called “extremophytes”. One successful strategy has been comparative studies between Arabidopsis thaliana and extremophyte Brassicaceae relatives such as the halophyte Eutrema salsugineum located in areas including cold, salty coastal regions of China. Here, we investigate stress tolerance in the desert species, Anastatica hierochuntica (True Rose of Jericho), a member of the poorly investigated lineage III Brassicaceae. We show that A. hierochuntica has a genome approximately 4.5-fold larger than Arabidopsis, divided into 22 diploid chromosomes, and demonstrate that A. hierochuntica exhibits tolerance to heat, low N and salt stresses that are characteristic of its habitat. Taking salt tolerance as a case study, we show that A. hierochuntica shares common salt tolerance mechanisms with E. salsugineum such as tight control of shoot Na+ accumulation and resilient photochemistry features. Furthermore, metabolic profiling of E. salsugineum and A. hierochuntica shoots demonstrates that the extremophytes exhibit both species-specific and common metabolic strategies to cope with salt stress including constitutive up-regulation (under control and salt stress conditions) of ascorbate and dehydroascorbate, two metabolites involved in ROS scavenging. Accordingly, A. hierochuntica displays tolerance to methyl viologen-induced oxidative stress suggesting that a highly active antioxidant system is essential to cope with multiple abiotic stresses. We suggest that A. hierochuntica presents an excellent extremophyte Arabidopsis relative model system for understanding plant survival in harsh desert conditions.
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Correlation-Based Network Generation, Visualization, and Analysis as a Powerful Tool in Biological Studies: A Case Study in Cancer Cell Metabolism

BioMed Research International is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in several areas of life sciences.
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Here we introduce one of a series of methods for correlation-based network generation and analysis using freely available software. The pipeline allows the user to control each step of the network generation and provides flexibility in selection of correlation methods and thresholds
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Frontiers | Salt Induces Features of a Dormancy-Like State in Seeds of Eutrema (Thellungiella) salsugineum, a Halophytic Relative of Arabidopsis | Plant Physiology

Frontiers | Salt Induces Features of a Dormancy-Like State in Seeds of Eutrema (Thellungiella) salsugineum, a Halophytic Relative of Arabidopsis | Plant Physiology | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
The salinization of land is a major factor limiting crop production worldwide.
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The article explores the molecular mechanisms underlying the paradoxically higher sensitivity to salt of halophyte Eutrema prior to germination.
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How I Got Converted to G.M.O. Food, from the New York Times by Mark Lynas

How I Got Converted to G.M.O. Food, from the New York Times by Mark Lynas | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
“ We can’t deny the science: Biotech works — for good.”
Via Mary Williams, Christophe Jacquet
Aaron Fait's insight:
flawed science, close-to -criminal activism, religious ideology and terrorizing ignorance are behind anti-GMO campaign
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Popular pesticide hurts wild bees in major field study
by By Seth Borenstein

Popular pesticide hurts wild bees in major field study<br/>by By Seth Borenstein | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Description
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It's not GM but classic old pal pesticide killing insect biodiversity
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Italy braces for smallest harvest since 1950

Italy braces for smallest harvest since 1950 | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
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The 2014 season overwhelmingly wet followed two seasons of severe drought events in the North-Eastern regions of Italy. It poses the question if in climate change hit regions there can be a true terroir element that can be maintained over more than a couple of seasons. 

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California Drought Just Broke A 120-Year Record

California Drought Just Broke A 120-Year Record | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Drought-stricken California, which just had its driest January ever recorded, smashed another dismal record last month: the hottest February.

Peter Gleick, a climate, water and sustainability scientist and member of the U.S.
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Electronic tongue: Savor the savior of the Galilee? - Science & Medicine

Electronic tongue: Savor the savior of the Galilee? - Science & Medicine | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
An Israeli college has replaced human tasters with a high-tech one that, in addition to developing the perfect pomegranate drink, could boost agricultural exports and more.
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Canadian company's genetically modified apples win US approval

Canadian company's genetically modified apples win US approval | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Twin varieties have been designed to resist browning but organic advocates say selling the fruit amounts to a ‘big experiment on humans’
Aaron Fait's insight:

"This is a very innocuous intervention where we’ve used an apple’s own DNA to turn off the protein called polyphenol oxidase that makes it go brown"... But ignorance is a tough beast.

 

http://modernfarmer.com/2014/01/arctic-apple/

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Malaria parasite manipulates host's scent

Malaria parasite manipulates host's scent | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Malaria parasites alter the chemical odor signal of their hosts to attract mosquitos and better spread their offspring, according to researchers, who believe this scent change could be used as a diagnostic tool.
Aaron Fait's insight:

Tritrophic interaction in malaria shed light on the role of metabolism in the transmission of this disease.

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BMC Plant Biology | Full text | Metabolic patterns associated with the seasonal rhythm of seed survival after dehydration in germinated seeds of Schismus arabicus

BMC Plant Biology | Full text | Metabolic patterns associated with the seasonal rhythm of seed survival after dehydration in germinated seeds of Schismus arabicus | The laboratory for Plant Metabolism and Metabolic Networks | Scoop.it
Seed of Shismus arabicus, a desert annual, display a seasonal tolerance to dehydration. The occurrence of a metabolic seasonal rhythm and its relation with the fluctuations in seed dehydration tolerance was investigated.
Aaron Fait's insight:

Yearly biorhythm of tolerance to dehydration in seeds of desert annual Shismus arabicus is associated with distinct seasonal metabolic features, occurring at the onset of germination sensu stricto.

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Bing Bai's curator insight, February 17, 2015 6:06 AM

Seasonal controlled metabolic variation during seed germination and dehydration correlates with seed survival. The metabolic adaptation for the plants survival in the desert provide good model to explore the endogenous mechanisms underpinning the seed dehydration tolerance regarding the fitness in the desert.