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Chromosomal organization and evolutionary histo...

Chromosomal organization and evolutionary histo... | TEs | Scoop.it
“With the aim to increase the knowledge on the evolution of coleopteran genomes, we investigated through cytogenetics and nucleotide sequence analysis Mariner transposons in three Scarabaeinae species (Coprophanaeus cyanescens, C.”
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Transposable elements

“For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html A tra...”
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Mobile DNA | Full text | Transposable element evolution in ...

Mobile DNA | Full text | Transposable element evolution in ... | TEs | Scoop.it
“Transposable elements (TEs) have the potential to impact genome structure, function and evolution in profound ways. In order to understand the contribution of transposable elements (TEs) to Heliconius melpomene, we ...”
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PLOS ONE: Transcriptional Activity, Chromosomal Distribution and Expression Effects of Transposable Elements in Coffea Genomes

PLOS ONE: Transcriptional Activity, Chromosomal Distribution and Expression Effects of Transposable Elements in Coffea Genomes | TEs | Scoop.it
“ PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.”
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Transposons overview

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Aging cells lose their grip on controling transposable elements

Aging cells lose their grip on controling transposable elements | TEs | Scoop.it
Transposable elements are mobile strands of DNA that insert themselves into chromosomes with mostly harmful consequences. Cells try to keep them locked down, but in a new study, Brown University researchers report that aging cells lose their ability to maintain this control. The result may be a further decline in the health of senescent cells and of the aging bodies they compose. Even in our DNA there is no refuge from rogues that prey on the elderly. Parasitic strands of genetic material called transposable elements—transposons—lurk in our chromosomes, poised to wreak genomic havoc. Cells have evolved ways to defend themselves, but in a new study, Brown University researchers describe how cells lose this ability as they age, possibly resulting in a decline in their function and health. Barbara McClintock, awarded the Nobel Prize in 1983, made the original discovery of transposons in maize. Since then scientists have found cases in which the chaos they bring can have long-term benefits by increasing genetic diversity in organisms, but in most cases the chaos degrades cell function, such as by disrupting useful genes. "The cell really is trying to keep these things quiet and keep these things repressed in its genome," said John Sedivy, professor of medical science in the Department of Molecular Biology, Cell Biology, and Biochemistry and senior author of the new study published online in the journal Aging Cell. "We seem to be barely winning this high-stakes warfare, given that these molecular parasites make up over 40 percent of our genomes." Cells try to clamp down on transposons by winding and packing transposon-rich regions of the genome around little balls of protein called nucleosomes. This confining arrangement is called heterochromatin, and the DNA that is trapped in such a tight heterochromatin prison cannot be transcribed and expressed. What the research revealed, however, is that carefully maintaining a heterochromatin prison system is a younger cell's game.
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Trends in Ecology and Evolution - Evolutionary transitions in individuality: insights from transposable elements

Trends in Ecology and Evolution - Evolutionary transitions in individuality: insights from transposable elements | TEs | Scoop.it
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