ScienceDaily
40 views | +0 today
Follow
Your new post is loading...
Your new post is loading...
Scooped by Wei Zhu
Scoop.it!

Stem cell therapy firm ReNeuron hires chief executive ahead of relocation to Wales in 2015 - RENE

Stem cell therapy firm ReNeuron hires chief executive ahead of relocation to Wales in 2015 - RENE | ScienceDaily | Scoop.it
“ Experienced pharmaceutical executive Olav Hellebø takes over from Michael Hunt, who has held the position of CEO since July 2005, with immediate effect. Mr - RENE”
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

Video: How a stem cell transplant works - Mayo Clinic

Video: How a stem cell transplant works - Mayo Clinic | ScienceDaily | Scoop.it
“During stem cell transplant treatment for cancer, healthy stem cells migrate to your bone marrow.”
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

Some stem cell methods closer to 'gold standard' than others

Some stem cell methods closer to 'gold standard' than others | ScienceDaily | Scoop.it
Researchers around the world have turned to stem cells, which have the potential to develop into any cell type in the body, for potential regenerative and disease therapeutics. Now, for the first time, researchers at the Salk ...
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

Wisconsin scientists find genetic recipe to turn stem cells to blood - Biology News Net (press release)

Wisconsin scientists find genetic recipe to turn stem cells to blood - Biology News Net (press release) | ScienceDaily | Scoop.it
Biology News Net (press release) Wisconsin scientists find genetic recipe to turn stem cells to blood Biology News Net (press release) Writing today in the journal Nature Communications, a group led by University of Wisconsin-Madison stem cell...
more...
No comment yet.
Rescooped by Wei Zhu from TAL effector science
Scoop.it!

Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing: Cell Stem Cell

Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing: Cell Stem Cell | ScienceDaily | Scoop.it

Via BigField GEG Tech, dromius
more...
BigField GEG Tech's curator insight, July 9, 2014 11:15 AM

The authors used CRISPR-Cas9 and TALEN to edit the genome of human pluripotent stem cell clones and they performed whole-genome sequencing at high coverage in order to assess the degree of mutagenesis across the entire genome. In both types of clones, they found that off-target mutations attributable to the nucleases were very rare. From this analysis, they suggest that, although some cell types may be at risk for off-target mutations, the incidence of such effects in human pluripotent stem cells may be sufficiently low and thus not a significant concern for disease modeling and other applications.

 

http://geg-tech.com/

Scooped by Wei Zhu
Scoop.it!

Researchers Use Human Stem Cells to Create Light Sensitive Retina in a Dish

Researchers Use Human Stem Cells to Create Light Sensitive Retina in a Dish | ScienceDaily | Scoop.it
Researchers have created a 3D human retinal tissue from stem cells.
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

Functional Nerve Cells from Skin Cells

Functional Nerve Cells from Skin Cells | ScienceDaily | Scoop.it
Researchers develop a new method of generating neurons from skin cells.
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

New stem cell research points to early indicators of schizophrenia

New stem cell research points to early indicators of schizophrenia | ScienceDaily | Scoop.it
Using new stem cell technology, scientists at the Salk Institute have shown that neurons generated from the skin cells of people with schizophrenia behave strangely in early developmental stages, providing a hint as to ways to detect and...
more...
No comment yet.
Rescooped by Wei Zhu from Adult Stem Cells Repair Body
Scoop.it!

STEM CELLS - Wiley Online Library

STEM CELLS - Wiley Online Library | ScienceDaily | Scoop.it

What did  YOU do for YOUR Stem Cells Today???


Via EJ Morris
more...
EJ Morris's curator insight, February 4, 2014 5:40 PM

Your OWN Stem Cells are amazing "Body Re-builders" . 

Stem Cells Work.. stem cells work Every Time .. *** BUT.. do you have ENOUGH of these Master Repair  Cells ? 

 

Do you want MORE stem cells in your blood?

 

Yes.. Every Day .. do you release  enough fresh bone marrow Adult Stem Cells to start circulating in your blood ... Stem Cells, that, then migrate into tissues and organs that need rejuvenated and repaired?

 

http://EJMorris.biz

 

Investigate daily stem cell nutrition advanced formula supplements... and find out how you can mobilize  up to 5 MILLION fresh adult stem cells into your bloodstream within  2 hours of consumption!

Stem Cell Nutrition supplementation is a huge wellness  discovery!

 

Follow a daily  Stem Cell Nutrition schedule  for Proactive Wellness and Health Maintenance.

http://EJMorris.com

 

 

Scooped by Wei Zhu
Scoop.it!

In Directing Stem Cells, Study Shows Context Matters

In Directing Stem Cells, Study Shows Context Matters | ScienceDaily | Scoop.it
“The stiffness of the surface on which stem cells grow can have a profound influence on the cell fate, a new study reports.”
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

USC Stem Cell scientists lay a trap for disease

USC Stem Cell scientists lay a trap for disease | ScienceDaily | Scoop.it
Colleagues tag four different types of kidney cells and identify early signals of acute kidney injury.
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

Cloned stem cells offer high fidelity - Nature.com

Cloned stem cells offer high fidelity - Nature.com | ScienceDaily | Scoop.it
Cloned stem cells offer high fidelity
Nature.com
Pluripotent stem cells can produce large supplies of, say, neurons or heart muscle, so are valuable for studying diseases and, potentially, for treating them.
more...
No comment yet.
Rescooped by Wei Zhu from TAL effector science
Scoop.it!

Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones - Cell Stem Cell

Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones - Cell Stem Cell | ScienceDaily | Scoop.it

Suzuki et al, 2014

The utility of genome editing technologies for disease modeling and developing cellular therapies has been extensively documented, but the impact of these technologies on mutational load at the whole-genome level remains unclear. We performed whole-genome sequencing to evaluate the mutational load at single-base resolution in individual gene-corrected human induced pluripotent stem cell (hiPSC) clones in three different disease models. In single-cell clones, gene correction by helper-dependent adenoviral vector (HDAdV) or Transcription Activator-Like Effector Nuclease (TALEN) exhibited few off-target effects and a low level of sequence variation, comparable to that accumulated in routine hiPSC culture. The sequence variants were randomly distributed and unique to individual clones. We also combined both technologies and developed a TALEN-HDAdV hybrid vector, which significantly increased gene-correction efficiency in hiPSCs. Therefore, with careful monitoring via whole-genome sequencing it is possible to apply genome editing to human pluripotent cells with minimal impact on genomic mutational load.


Via dromius
more...
dromius's curator insight, July 15, 2014 4:17 AM
Our WGS analysis of TALEN-edited hiPSCs shows no clear evidence of widespread off-target modification.
Scooped by Wei Zhu
Scoop.it!

Key Gene for Stem Cell Development Found - International Business Times UK

Key Gene for Stem Cell Development Found - International Business Times UK | ScienceDaily | Scoop.it
International Business Times UK
Key Gene for Stem Cell Development Found
International Business Times UK
Stem cells are a class of undifferentiated cells that are able to differentiate indefinitely into specialised cell types.
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

Cell culture : Nature Materials

Nature Materials journal covers a range of topics within materials science, from materials engineering and structural materials (metals, alloys, ceramics, composites) to organic and soft materials (glasses, colloids, liquid crystals, polymers).
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

Tests of Embryonic Stem Cell Treatment Back on Track - Science AAAS

Tests of Embryonic Stem Cell Treatment Back on Track - Science  AAAS | ScienceDaily | Scoop.it
Science AAAS Tests of Embryonic Stem Cell Treatment Back on Track Science AAAS A potential treatment for spinal cord injury that made headlines in 2010 as the first human embryonic stem cell therapy to be tested in humans is pushing ahead after a...
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

Neurons Signal Stem Cells to Make New Neurons - Genetic Engineering News

Neurons Signal Stem Cells to Make New Neurons - Genetic Engineering News | ScienceDaily | Scoop.it
Genetic Engineering News
Neurons Signal Stem Cells to Make New Neurons
Genetic Engineering News
Neuroscientists surmised that new neurons emerge when stem cells activate certain internal processes in response to environmental cues.
more...
No comment yet.
Scooped by Wei Zhu
Scoop.it!

First disease-specific human embryonic stem cell line by nuclear transfer

First disease-specific human embryonic stem cell line by nuclear transfer | ScienceDaily | Scoop.it
Using somatic cell nuclear transfer, a team of scientists led by Dr. Dieter Egli at the New York Stem Cell Foundation (NYSCF) Research Institute and Dr.
more...
No comment yet.