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Genetics in Mendelian Human Disease - Broad Institute (2012)

The Primer on Medical and Population Genetics is a series of informal weekly discussions of basic genetics topics that relate to human populations and disease.

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The Role of Criticality of Gene Regulatory Networks on Emergent Properties of Biological Systems

Center for Collective Dynamics of Complex Systems (CoCo) Seminar Series April 18, 2018 Hyobin Kim (Systems Science, Binghamton University)


Via Hiroki Sayama, Complexity Digest, june holley
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Becoming immortal [VPRO documentary, 2018]

Becoming immortal is now at hands reach, thanks to the latest technological innovations. Would you want to become immortal, even if that means preserving your severed head in a cryogenic tank? If aging is considered as a disease, then the cure is immortality. This is not a Black Mirror episode, this is VPRO Backlight: Becoming immortal.

Is eternal life reserved only for the rich or the lunatics of the earth? Silicon Valley is fascinated with the concept of overcoming death and rejuvenation. Billions are invested in becoming immortal. The idea is that when aging is considered as a disease, we can also develop a cure for dying and modify the natural lifecycle thanks to age reversing or anti aging therapy.

A tight community of scientists and entrepreneurs from Silicon Valley bear an enormous source of daring capital, like Aubrey de Grey says: ““If you’re not pissing everybody off in this life, then you’re probably not making much of a difference”.  This community is also firmly convinced that our DNA can be cracked in what would be called: The code of mortality, allowing us all to become immortal.

And if becoming immortal does not happen within their own life span, then it will certainly happen in the following years. Therefore many a millionaire has his own personal cryogenic tank ready for cryopreservation so they can be brought back to life after death. Whether it will be in material form or in the form of a software program (digital immortality) or as nanobots remains to be seen.

Some can not wait that long and use themselves as guinea pigs. All of them hope to become immortal. The science in the field of life extension is a booming business. The question remains whether everyone can benefit from this groundbreaking knowledge and become immortal.

With: Aubrey de Grey (Scientist), Liz Parrish (Bioviva), Darren Moore (Millionaire) and Kathleen Ann Goonan (Science-fiction writer), Linda Chamberlain (Alcor). Originally broadcasted by VPRO in 2018.

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Will the 21st Century be the Time we Discover Life Beyond Earth?

In 2004, Craig Venter & Daniel Cohen suggested that if the 20th century was the century of physics, the 21st century will be the century of biology on our planet.

 

Jill Tarter believes that their idea will be extended beyond the surface of our world and that we may soon have the first opportunity to study biology that developed on other worlds. She talks about her vision of the future of understanding life on Earth and beyond our planet. And she discusses projects that are underway and are planned to learn more about the possibility of intelligent life among the stars. This talk also celebrates the publication of the book "Making Contact" (by Sarah Scoles) about Jill Tarter's life and work.

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Ray Kurzweil: The Power of Ideas to Transform The World As We Know It - SXSW 2018

Ray Kurzweil is one of the world’s leading inventors, thinkers, and futurists, with a thirty-year track record of accurate predictions. Share his ideas on hacking the human brain with technology. Called “the restless genius” by The Wall Street Journal and “the ultimate thinking machine” by Forbes magazine, he was selected as one of the top entrepreneurs by Inc. magazine, which described him as the ”rightful heir to Thomas Edison.” PBS has selected him as one of the “sixteen revolutionaries who made America.”

 

About SXSW:
Started in 1987, South by Southwest (SXSW) is a set of film, interactive, and music festivals and conferences that take place early each year in mid-March in Austin, Texas. SXSW’s original goal was to create an event that would act as a tool for creative people and the companies they work with to develop their careers, to bring together people from a wide area to meet and share ideas. That continues to be the goal today whether it is music, film or interactive technologies.

Connect with SXSW Online: http://www.sxsw.com

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Timelaps of the Entire Universe

On a cosmic time scale, human history is as brief as the blink of an eye. By compressing all 13.8 billion years of time into a 10 minute scale, this video shows just how young we truly are, and just how ancient and vast our universe us. Starting with the big bang and culminating in the appearance of homo sapiens, this experience follows the unfolding of time at 22 million years per second, adhering closely to current scientific understanding.


Via David McConville
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The Riddle of the Quantum Sphinx: Robert Spekkens Talks About a Different View In Regards To Quantum Mechanics

In his Feb. 7 public lecture at Perimeter Institute, Robert Spekkens will explain why he believes that many quantum mysteries are a result of a categor
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DeepMind - The Role of Multi-Agent Learning in Artificial Intelligence Research

Thore Graepel is a Research Scientist at Google DeepMind, and Professor of Computer Science at UCL. Recorded: March, 2017
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Machine Super Intelligence - Shane Legg on AI [12 Video Lectures]

Machine Super Intelligence - Shane Legg on AI [12 Video Lectures] | Science-Videos | Scoop.it

What ever happened to the ambitious aims of artificial intelligence, specifically, its original goal of creating an "intelligent machine"? Are we any closer to this than we were 20 or 30 years ago? Indeed, have we made any progress on figuring out what intelligence is, let alone knowing how to build one? After all, if we had a clearer idea of where we want to get to, we might be able to come up with some better ideas on how to get there!

Clearly, artificial intelligence could do with a better theoretical foundation. This talk will outline work on creating such a foundation:

*) What is intelligence?
*) How can we formalise machine intelligence?
*) Solomonoff Induction: a universal prediction system.
*) AIXI: Hutter's universal artificial intelligence.
*) MC-AIXI: a computable approximation of AIXI.
*) Can the brain tell us anything useful for building an AI?
*) Is building a super intelligent machine a good idea?

** About the speaker:

Dr Shane Legg is a post doctoral research associate at the Gatsby Computational Neuroscience Unit, University College London. He received a PhD in 2008 from the Department of Informatics, University of Lugano, Switzerland. His PhD supervisor was Prof. Marcus Hutter, the originator of the AIXI model of optimal machine intelligence.

Upon the completion of his PhD he won the $10,000 Canadian Singularity Institute for Artificial Intelligence Prize and was also awarded a post doctoral research grant by the Swiss National Science Foundation.

Shane is a native of New Zealand. After training in mathematics he began a career as a software engineer, mostly for American companies specialising in artificial intelligence. In 2003 he returned to academia to complete a PhD.

His research has been published in top academic journals (e.g. IEEE TEC), and featured in mainstream publications (e.g. New Scientist). All of Shane's publications, including his doctoral thesis "Machine super intelligence", are available on his website, http://www.vetta.org

This lecture was recorded on 31st of October 2009 at the UKH+ meeting. For information on further meetings please see:
http://extrobritannia.blogspot.com/

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Deepmind Alpha Zero: Reinforced Learning Course by David Silver (10 Video Lectures)

#Reinforcement Learning Course by David Silver# Lecture 1: Introduction to Reinforcement Learning #Slides and more info about the course: http://goo.gl/vUiyjq

 

Dr. David Silver leads the reinforcement learning research group at DeepMind and is lead researcher on AlphaGo. He graduated from Cambridge University in 1997 with the Addison-Wesley award. Subsequently, David co-founded the video games company Elixir Studios, where he was CTO and lead programmer, receiving several awards for technology and innovation.[1][2] David returned to academia in 2004 at the University of Alberta to study for a PhD on reinforcement learning, where he co-introduced the algorithms used in the first master-level 9x9 Go programs.[3] David was awarded a Royal Society University Research Fellowship in 2011, and subsequently became a lecturer at University College London, where he is now a professor.[4]His lectures on Reinforcement Learning are available on YouTube[5]. David consulted for DeepMind from its inception, joining full-time in 2013.

 

His recent work has focused on combining reinforcement learning with deep learning, including a program that learns to play Atari games directly from pixels.[6] David led the AlphaGo project, culminating in the first program to defeat a top professional player in the full-size game of Go.[7]AlphaGo subsequently received an honorary 9 Dan Professional Certification; and won the Cannes Lion award for innovation.[8]. He then led development of AlphaZero, which used the same AI to learn to play Go from scratch (learning only by playing itself and not from human games) before learning to play chess and shogi in the same way, to higher levels than any other computer program[9].

 

David is the most published member of staff at DeepMind and has an h-index of 34.[10]

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Next-generation Brain Interfaces

Next-generation Brain Interfaces | Science-Videos | Scoop.it
Andrew Schwartz discusses how emerging computing interfaces will change medicine.
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Declassified! LLNL Atmospheric Nuclear Test Videos

Declassified! LLNL Atmospheric Nuclear Test Videos | Science-Videos | Scoop.it
The U.S. conducted 210 atmospheric nuclear tests between 1945 and 1962, with multiple cameras capturing each event at around 2,400 frames per second. These are the declassified films of tests conducted by Lawrence Livermore National Laboratory.
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Breakthrough in Nuclear Fusion?

Nuclear fusion is the holy grail of energy generation because by fusing two hydrogen atoms together into a single helium atom it releases enormous amounts of energy, yet represents a clean, safe, sustainable and secure form of power.

The most tried and true approach for generating nuclear fusion energy has been a tokamak fusion reactor, which uses very high density magnetic fields to compress and contain a plasma to 100 million degrees. But none has been able to generate more electricity than it consumes. Until now.

Director Whyte will describe the ARC nuclear fusion reactor (shown above right), based on a new superconducting material, for achieving very high density magnetic fields. It will be used as a research center, but could ultimately become a prototype for an inexpensive 200MW power plant, vaulting nuclear fusion from scientific curiosity to potential commercialization.

The ARC reactor is being designed to produce at least 3 times the power required to run it, which has never been done before and is the result of several new technologies which dramatically reduce the size and cost.

The biggest breakthrough is a new superconducting material which produces a much higher magnetic field density, yielding a ten-fold increase in fusion power per volume. Molten salt will be used as a liquid cooling blanket for fast heat transfer and easy maintenance. And 3D printing techniques will allow the fabrication of reactor components in shapes that cannot be made by milling machines. The result is a much smaller, lower cost and highly efficient modular power plant with zero emissions and abundant fuel.

Dennis Whyte, recently promoted to run MIT’s Nuclear Science and Engineering Department and Director of MIT’s Plasma Science & Fusion Center, works in magnetic fusion and specializes in the interface between the plasma and materials.

Dennis received his PhD from the Universite du Quebec in 1993. A Fellow of the American Physical Society, Dennis was awarded the Department of Energy’s Plasma Physics Junior Faculty Award in 2003 and won the International Atomic Energy Agency’s Nuclear Fusion Prize in 2013. He is a two-time winner of the MIT Joel and Ruth Spira Award for teaching excellence. Among his many lectures on fusion energy research, Dennis was an invited speaker at CERAWeek and the National Science Foundation’s Engineering Distinguished Lecturer in 2015.

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Implantable Optoelectronic and Microfluidic Systems for Neuroscience

Professor John Rogers, Professor of Materials Science and Engineering, University of Illinois, discusses how the successful integration of optoelectronic and microfluidic systems with the brain has the potential to accelerate basic scientific discoveries and their translation into clinically relevant technologies. Professor Rogers’ research includes fundamental and applied aspects of materials for unusual electronic and photonic devices, with an emphasis on bio-integrated and bio-inspired systems.

 

https://neuroscience.stanford.edu

 

Part of the Inaugural Symposium of Stanford Neurosciences Institute recorded on October 9, 2014.

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NVIDIA's Artificial Intelligence GPU Revolution - TITAN V

TITAN V has the power of 12 GB HBM2 memory and 640 Tensor Cores, delivering 110 TeraFLOPS of performance.
CEO Jensen Huang's GTCJapan keynote on Dec. 13th, 2017
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Fast Radio Bursts - Nature's Latest Cosmic Mystery

Fast Radio Bursts are millisecond-duration pulses of unknown origin that were discovered by pulsar astronomers in 2007. A decade on from the discovery, with only 20 further bursts currently known, fast radio bursts remain enigmatic sources which parallel the early days of gamma-ray burst astronomy in the early 1970s. This video tells the story of their discovery, summarize what we know about them so far, describe the science opportunities these bursts present, and make predictions for what we may learn in the next decade.

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The End of the Universe - Is it a Big Crunch, Big Freeze or a Big Rip?

The End of the Universe: Is it going to be a Big Crunch, Big Freeze or a Big Rip? These scenarios are discussed in this Video.

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Turing Lecture: Better living through trusted data

Big Data, AI, and social media echo chambers can feel scary, but if harnessed correctly they can dramatically improve our quality of life. The potential for improvement comes first from better scientific understanding of our human minds and bodies, and second from a more open and shared understanding of society, government, and our day-to-day lives. The key to achieving these positive results is aggressive pursuit of a new, broad science of human life to unify the traditional and narrow sciences, and making data a trusted and safe resource for everyone. We are building such systems today, and are changing “business as usual” for governments around the world, as well as beginning to unify fragmented social and computational sciences.


Via Complexity Digest
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Alien Galaxies

To know our place in the universe take a look far, far away to the realm of Alien Galaxies. Our galaxy is one of hundreds of billions in the universe. 

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Is Anyone out There? The Hundred-Million Dollar "Breakthrough: Listen" Project

What is the possibility of other intelligent life in the universe and how might we detect signals from alien civilizations?

 

Dr. Werthimer describes current and future projects searching for such signals, including the new $100-million Breakthrough Prize Foundation Listen project. He shows how new technologies are revolutionizing the search for extra-terrestrial intelligence (SETI). He also discusses the SETI@home project, which analyzes data from the world's largest radio telescope using desktop computers and cell phones from millions of volunteers.

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PBS Space Time Videos [231 Educational Videos]

PBS Space Time Videos [231 Educational Videos] | Science-Videos | Scoop.it

Join astrophysicist Matt O’Dowd on a journey through the deepest, darkest, coolest corners of the universe. Math, physics, and astronomy can’t get much bigger than this.

 

On the acclaimed PBS Digital Studios series Space Time, Matt explores the outer reaches of space, the craziness of astrophysics, the possibilities of sci-fi, and anything else you can think of beyond Planet Earth. Visit the series home on YouTube for new weekly episodes and challenges that prompt your classroom to think differently about physics and push the rules of space and time to the limit.

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2018 Breakthrough Prize Symposium: What Can We Learn in the Next 10 Years About the Universe's Beginning and End?

David Spergel: 2018 Breakthrough Prize Symposium: What Can We Learn in the Next 10 Years About the Universe's Beginning and End? The 2018 Breakthrough Priz
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Are We Alone? A New Era in Astronomy is on the Horizon: The NASA James Webb Space Telescope

The Hubble Space Telescope has completely revolutionized our understanding of the universe, and has become a beloved icon of popular culture. As revolutionary as Hubble has been, we have pushed it to its scientific limits in many ways. Hubble’s successor, the James Webb Space Telescope, has been in the works for almost two decades and is scheduled to launch in late 2018. It will be 100 times more powerful than Hubble. In her Perimeter Public Lecture, Dr. Amber Straughn will provide an update on the progress of building the world’s largest-yet space telescope, and will give an overview of the astronomical questions we hope to answer with Webb. These questions get to the heart of what it means to be human: Where did we come from? How did we get here? Are we alone?
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Hidden Structures of the Mandelbrot and Julia Sets

An exploration of the correlations between the Mandelbrot Set and the Julia Sets for z^2 + c. Followed by some flybys of the full Mandelbrot/Julia structures. Finally, an attempt to show the complete 4D Mandelbrot Set.

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