RHEUMATOLOGY
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Automated system may help identify patients at high risk for osteoporosis | Orthopedics

Automated system may help identify patients at high risk for osteoporosis | Orthopedics | RHEUMATOLOGY | Scoop.it
Orthopedics | Using an automated system to identify patients being treated for fractures who are at high risk for osteoporosis and generating letters to these patients to encourage follow-up can be an effective way to promote osteoporosis intervention...
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Romosozumab in Postmenopausal Women with Low Bone Mineral Density — NEJM

Romosozumab in Postmenopausal Women with Low Bone Mineral Density — NEJM | RHEUMATOLOGY | Scoop.it
Original Article from The New England Journal of Medicine — Romosozumab in Postmenopausal Women with Low Bone Mineral Density

Via Krishan Maggon
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Krishan Maggon 's curator insight, January 2, 2014 1:40 AM

In postmenopausal women with low bone mass, romosozumab (Amgen) was associated with increased bone mineral density and bone formation and with decreased bone resorption. Sclerostin is an osteocyte-derived inhibitor of osteoblast activity. The monoclonal antibody romosozumab binds to sclerostin and increases bone formation.

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Colles' fracture and osteoporosis are independent predictors of hip fracture - Healio

Colles' fracture and osteoporosis are independent predictors of hip fracture - Healio | RHEUMATOLOGY | Scoop.it
Colles' fracture and osteoporosis are independent predictors of hip fracture
Healio
In the study, which was presented at a recent Osteoporosis Foundation meeting in Hong Kong, researchers T.-L. Huang and C.-W.
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Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: Efficacy and safety results from the randomised SARIL-R...

Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: Efficacy and safety results from the randomised SARIL-R... | RHEUMATOLOGY | Scoop.it
Rheumatology Medical Article: Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: Efficacy and safety results from the randomised SARIL-RA-MOBILITY Part A...

Via Gilbert C FAURE
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Rescooped by Robert Coughlan from Rheumatology-Rhumatologie
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His favourite 10 rheumatology papers from 2013

His favourite 10 rheumatology papers from 2013 | RHEUMATOLOGY | Scoop.it
My favourite 10 Rheumatology papers from 2013.
Joint Venture: 10 out of 10 - My favourite 10 rheumatology papers... http://t.co/vYD0KIgWOJ

Via Gilbert C FAURE
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58% of Saudi women suffer from osteoporosis - Arab News

58% of Saudi women suffer from osteoporosis - Arab News | RHEUMATOLOGY | Scoop.it
58% of Saudi women suffer from osteoporosis
Arab News
The incidence of osteoporosis in the Kingdom recently reached alarming levels compared to other countries, registering 58 and 32.2 percent for women and men respectively.
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Resistance, Aerobic Training May Reduce Pain in Fibromyalgia - Medscape

Resistance, Aerobic Training May Reduce Pain in Fibromyalgia
Medscape
The trend toward including exercise training in fibromyalgia (FM) treatment programs gained support from a Cochrane Collaboration review published online December 20, 2013.
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Damon Murgatroyd's curator insight, April 5, 7:34 AM
FM is a scourge - any good evidence on therapy is welcome.
Dr Damon Murgatroyd
Rescooped by Robert Coughlan from Immunology and Biotherapies
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Monoclonal Antibody Associated with Increased Bone Density in Osteoporosis

By Joe Elia Romosozumab, a monoclonal antibody against an inhibitor of bone formation, increases bone mineral density, a New England Journal of Medicine (RT @Physns1stWatch: Monoclonal antibody associated with increased bone density in #osteoporosis...

Via Gilbert C FAURE
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Rescooped by Robert Coughlan from Top Selling Monoclonal Antibodies 2014
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European CHMP positive opinion of Roche's new subcutaneous formulation of RoACTEMRA for rheumatoid arthritis

European CHMP positive opinion of Roche's new subcutaneous formulation of RoACTEMRA  for rheumatoid arthritis | RHEUMATOLOGY | Scoop.it

Upon approval, RoACTEMRA would be the first IL-6 biologic available in subcutaneous and intravenous administration for both monotherapy and combination therapyNew subcutaneous formulation would offer greater flexibility for rheumatoid arthritis patients

Roche announced today that the subcutaneous formulation of RoACTEMRA (tocilizumab) has received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) for the treatment of moderate to severe active rheumatoid arthritis (RA) in patients who have either responded inadequately to, or who are intolerant to, previous therapy with one or more disease modifying anti-rheumatic drugs (DMARDs) or tumour necrosis factor (TNF) inhibitors.

As with the intravenous (IV) formulation indication, the CHMP has recommended approval of the subcutaneous formulation for use both as monotherapy and in combination with methotrexate (MTX).


Via Krishan Maggon
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Rescooped by Robert Coughlan from Rheumatology-Rhumatologie
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Arthritis Research & Therapy | Full text | Towards the elucidation of ...

Adipo(cyto)kines are mostly produced by adipose tissue and orchestrate the adverse impact of excess adiposity on cardiovascular risk. Adipokines also contribute importantly to the pathophysiology of rheumatoid arthritis.

Via Gilbert C FAURE
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National Osteoporosis Foundation Launches First Fracture Prevention Initiative ... - PR Newswire (press release)

National Osteoporosis Foundation Launches First Fracture Prevention Initiative ... - PR Newswire (press release) | RHEUMATOLOGY | Scoop.it
National Osteoporosis Foundation Launches First Fracture Prevention Initiative ...
PR Newswire (press release)
Fracture Liaison Service Programs are the Solution to Reducing the Two Million Bone Breaks Caused by Osteoporosis Each Year.
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Molecular Pathway Discovery May Help Treat Psoriasis, Crohn's Disease, Arthritis - Sci-News.com

Molecular Pathway Discovery May Help Treat Psoriasis, Crohn's Disease, Arthritis - Sci-News.com | RHEUMATOLOGY | Scoop.it
Sci-News.com
Molecular Pathway Discovery May Help Treat Psoriasis, Crohn's Disease, Arthritis
Sci-News.com
Molecular Pathway Discovery May Help Treat Psoriasis, Crohn's Disease, Arthritis. Dec 26, 2013 by Sci-News.com · « PREVIOUS.

Via Gilbert C FAURE
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