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Blood and Loss (Cassandra Myles Witch Series) eBook: Electa Graham: Amazon.co.uk: Kindle Store

Blood and Loss (Cassandra Myles Witch Series) eBook: Electa Graham: Amazon.co.uk: Kindle Store (Just finished reading this, it is perfect for Fantasy fans.)...
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Reading Pool
Reading resources for information on different  subjects
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Rescooped by jameel56 from All Things Bookish: All about books, all the time
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Writing snack. What’s your favorite snack?

Writing snack. What’s your favorite snack? | Reading Pool | Scoop.it
Writing snack. What’s your favorite snack?
Via Sara Rosett
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Rescooped by jameel56 from Aussizz Group
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Buying a Health Insurance Plan to Visit Australia? Know the 6 Most Important Terms!

Buying a Health Insurance Plan to Visit Australia? Know the 6 Most Important Terms! | Reading Pool | Scoop.it

Looking for health insurance cover to get a fast approval for your Australian visa? Struggling with complex medical terms and finding hard to make a decision? Our blog highlights some of the common terms that are important to consider while buying a health insurance plan.


Via Aussizz Group
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Rescooped by jameel56 from Digital Delights for Learners
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The best screen for every classroom! 

The best screen for every classroom!  | Reading Pool | Scoop.it
Quickly get a timer, textbox, noise meter, drawing tool, name picker, work symbols and more. Completely free.

Via Ana Cristina Pratas
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Marja Oilinki's curator insight, January 25, 5:30 AM
Yksinkertainen ja ilmainen työkalu, jolla voi opettajan ruudulta käyttää esimerkiksi äänenvoimakkuuden mittaamista, jakaa toimintaohjeita, muistuttaa siitä milloin tylskennellään hiljaa tai kuiskaten tai käyttää ruutua piirtoalustana. Ohjevideo löytyy YouTubesta ja sivu on helppo tuunata kutakin tuntia varten nopeasti halutuksi. 
 
António Leça Domingues's curator insight, January 26, 4:32 AM
Ecrã muito útil para uso em sala de aula.
Ramon Pavia's curator insight, January 31, 4:45 AM
Not bad at all. Suitable for hyperactive teachers...
Rescooped by jameel56 from Learning*Education*Technology
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A Dozen Ways to Make Amazingly Creative Book Reports

A Dozen Ways to Make Amazingly Creative Book Reports | Reading Pool | Scoop.it
Book reports don't have to be boring. Help your students make the books they read come alive with these 12 creative book report ideas.

Via Skip Zalneraitis
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Letterhead design's curator insight, January 16, 1:42 AM

Consider the shading plan of your online Custom Business Card Design services. In the event that you wish to use distinctive hues, constantly select the correct hues that can brilliant match the subject of your business cards. This procedure might be extremely pivotal since a slight confuse on shading will break your entire look of your enterprise cards. Consider that every shading speaks to an important, so make sure you pick the absolute best one for your independent company card formats.

Letterhead design's curator insight, January 16, 1:45 AM

On the off chance that you require the absolute best worth of your financial plan, avoid bargaining the nature of the paper stock that you'll utilize. Select the right of paper stock to guarantee its high caliber and adequacy. It's fundamental to avoid utilizing minimal effort and temperamental paper shares since they are going to just harm the overall usefulness and adequacy of what you are Custom Business Card Design services. However much as could reasonably be expected, utilize high review and overwhelming commitment paper stock

Rescooped by jameel56 from FUE Hair Transplant in Dubai
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How Stress Can Be Associated With Hair Loss?

How Stress Can Be Associated With Hair Loss? | Reading Pool | Scoop.it
Hair loss treatment in Dubai can permanently cure all the stress-related types of hair loss. Read how stress can be associated with hair loss? Read More.

Via malika iman
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BitClave - Decentralized Search Engine

BitClave - Decentralized Search Engine | Reading Pool | Scoop.it
The BitClave Token Sale is about to start! Place your deposit now and get a 30% bonus!
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Rescooped by jameel56 from Going Digital
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The 5 Best Free Digital Magazine Creation Tools for Teachers - eLearning Industry

The 5 Best Free Digital Magazine Creation Tools for Teachers - eLearning Industry | Reading Pool | Scoop.it
Check The 5 Best Free Digital Magazine Creation Tools for Teachers and How To Use The 5 Best Free Digital Magazine Creation Tools for Teachers.

Via Sarah McElrath
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Sarah McElrath's curator insight, November 1, 2017 8:06 AM
From simple (Fodey Newspaper Clipping Generator) to more sophisticated (Joomag), these digital magazine creation tools will add an excited twist to writing a report/essay.
Karen Mejia's curator insight, November 29, 2017 2:56 PM
This article mentions the importance of challenging students and to use technology in the classroom encouraging students to create digital magazine and according to their interest and using the L2.   
Rescooped by jameel56 from iGeneration - 21st Century Education (Pedagogy & Digital Innovation)
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Typeset Web Tool for Research Students and Academics via Educators' technology

Typeset Web Tool for Research Students and Academics via Educators' technology | Reading Pool | Scoop.it
Free resource of educational web tools, 21st century skills, tips and tutorials on how teachers and students integrate technology into education

Via Tom D'Amico (@TDOttawa)
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Rescooped by jameel56 from Digital Delights for Learners
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Quest - Write text adventure games and interactive stories

Quest - Write text adventure games and interactive stories | Reading Pool | Scoop.it

Via Ana Cristina Pratas
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Oskar Almazan's curator insight, October 23, 2017 8:46 AM
Quest lets you make interactive story games. Text adventure games like Zork and The Hitchhiker's Guide to the Galaxy. Gamebooks like the Choose Your Own Adventure and Fighting Fantasy books. You don't need to know how to program. All you need is a story to tell. Your game can be played anywhere. In a web browser, downloaded to a PC, or turned into an app.
 
Ricard Garcia's curator insight, October 24, 2017 4:46 AM
Interesting tool to foster creativity in storytelling and narrative... a bit complex but rewarding if teachers devote some time to learn the tool.
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New Da Vinci Robot is changing the game for local doctors

New Da Vinci Robot is changing the game for local doctors | Reading Pool | Scoop.it
A new robot used to perform surgeries at the Ventura County Medical Center is changing the game of medicine.
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Right Relevance : Influencers, Articles and Conversations

Right Relevance : Influencers, Articles and Conversations | Reading Pool | Scoop.it
Discover fresh relevant content to your interests, save interesting articles, follow influential experts, be the first to share soon-to-be viral content and much more
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Roblox NBA Phenom: Team Chemistry, Raining 3's!

Drafted to the Brooklyn nets and got the W! Make sure you leave a like and subscribe to help me grow! X
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Grave Mysteries Season 1 Episode 5 Killer Chemistry

Watch Grave Mysteries Season 1 Episode 5 - Full Episode Click Link Side To Watch: http://yuyayu69.stream/tv/73751-1-5 Grave Mysteries Season 1 Episode
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Rescooped by jameel56 from Digital Delights for Learners
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H5P – Create and Share Rich HTML5 Content and Applications

H5P – Create and Share Rich HTML5 Content and Applications | Reading Pool | Scoop.it
H5P empowers everyone to create, share and reuse interactive content - all you need is a web browser and a web site that supports H5P.

Via Ana Cristina Pratas
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Rescooped by jameel56 from Digital Delights for Learners
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TeacherGaming Desk

TeacherGaming Desk | Reading Pool | Scoop.it
TeacherGaming Desk - An all-in-one GBL solution. Lesson plans to fine-tuned analytics.

Via Ana Cristina Pratas
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Rescooped by jameel56 from EDUCACIÓN en Puerto TIC
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App Inventor en Español

App Inventor en Español | Reading Pool | Scoop.it

Aprende a desarrollar aplicaciones para Android con App Inventor.
Manuales y tutoriales de App Inventor en Español.


Via PuertoTICs
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Rescooped by jameel56 from Edtech PK-12
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Top 100 Free Education Sites

Top 100 Free Education Sites | Reading Pool | Scoop.it
Since 2013, Help Teaching has brought you our Top 100 Free Education Sites. We're continually updating our list to provide you with the best resources.

Via Cindy Rudy
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Rescooped by jameel56 from Digital Delights for Learners
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Let Me Tell You a Story - A Writing Tool for Storytelling

Let Me Tell You a Story - A Writing Tool for Storytelling | Reading Pool | Scoop.it

Via Ana Cristina Pratas
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Rescooped by jameel56 from All Things Bookish: All about books, all the time
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Another Agatha Christie movie adaptation. Don’t you love this cover? It’s one of my all-time favorites @officialagathachristie (@get_repost) ・・・ Death on the Nile has been announced as the next Aga...

Another Agatha Christie movie adaptation. Don’t you love this cover? It’s one of my all-time favorites @officialagathachristie (@get_repost) ・・・ Death on the Nile has been announced as the next Aga... | Reading Pool | Scoop.it
Another Agatha Christie movie adaptation. Don’t you love this cover? It’s one of my all-time favorites. #agathachristie #movieadaptation #booktofilm #mysterybooks #goldenage ~ #Repost @officialagathachristie (@get_repost) ・・・ Death on the Nile has been announced as the next Agatha Christie novel to b
Via Sara Rosett
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Rescooped by jameel56 from All Things Bookish: All about books, all the time
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Out now! The sixth book in the On The Run series, Treacherous, a lighthearted globetrotting adventure with intrigue and mystery. Link in profile or http://www.sararosett.com/new-3 | Sara Rosett

Out now! The sixth book in the On The Run series, Treacherous, a lighthearted globetrotting adventure with intrigue and mystery. Link in profile or http://www.sararosett.com/new-3 | Sara Rosett | Reading Pool | Scoop.it
Out now! The sixth book in the On The Run series, Treacherous, a lighthearted globetrotting adventure with intrigue and mystery. Link in profile or http://www.sararosett.com/new-3 #mysterybooks #newrelease #bookbirthday
Via Sara Rosett
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Rescooped by jameel56 from All Things Bookish: All about books, all the time
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The saga of the bathroom update continues...with bricks. Yes, it looks like we removed a fireplace but we didn’t. We found all those bricks under a seat when we tore out the old shower. What’s the ...

The saga of the bathroom update continues...with bricks. Yes, it looks like we removed a fireplace but we didn’t. We found all those bricks under a seat when we tore out the old shower. What’s the ... | Reading Pool | Scoop.it
The saga of the bathroom update continues...with bricks. Yes, it looks like we removed a fireplace but we didn’t. We found all those bricks under a seat when we tore out the old shower. What’s the strangest thing you’ve found while remodeling or cleaning? #remodeling #writerlife #weirdfinds
Via Sara Rosett
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Medicine Hat Charity Classic

Medicine Hat Charity Classic | Reading Pool | Scoop.it
<<<<  >>>> Fri, Oct 20 -- 6:00pm -- Times shown as Mountain Time (MT).Team HMR  1   2   3   4   5   6   7   8  Score  Daria Morozova Moscow, RUS      0   0   0   1   1   1   0   X   3   Jessie Hunkin Edmonton, AB    1   0   0   0   0   0   1   X   2   View Game Details Admin  Skip: Daria Morozova...
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Ancient Kill Switch: Scientists Discover Suicide Molecule That Can Kill Any Cancer Cell

Ancient Kill Switch: Scientists Discover Suicide Molecule That Can Kill Any Cancer Cell | Reading Pool | Scoop.it



Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.The mechanism -- RNA suicide molecules -- can potentially be developed into a novel form of cancer therapy, the study authors said.Cancer cells treated with the RNA molecules never become resistant to them because they simultaneously eliminate multiple genes that cancer cells need for survival."It's like committing suicide by stabbing yourself, shooting yourself and jumping off a building all at the same time," said Northwestern scientist and lead study author Marcus Peter. "You cannot survive."$$!ad_code_content_spilt_video_ad!$$The inability of cancer cells to develop resistance to the molecules is a first, Peter said."This could be a major breakthrough," noted Peter, the Tom D. Spies Professor of Cancer Metabolism at Northwestern University Feinberg School of Medicine.Peter and his team discovered sequences in the human genome that when converted into small double-stranded RNA molecules trigger what they believe to be an ancient kill switch in cells to prevent cancer. He has been searching for the phantom molecules with this activity for eight years."We think this is how multicellular organisms eliminated cancer before the development of the adaptive immune system, which is about 500 million years old," he said. "It could be a fail safe that forces rogue cells to commit suicide. We believe it is active in every cell protecting us from cancer."This study, which will be published Oct. 24 in eLife, and two other new Northwestern studies in Oncotarget and Cell Cycle by the Peter group, describe the discovery of the assassin molecules present in multiple human genes and their powerful effect on cancer in mice.Looking back hundreds of millions of yearsWhy are these molecules so powerful?"Ever since life became multicellular, which could be more than 2 billion years ago, it had to deal with preventing or fighting cancer," Peter said. "So nature must have developed a fail safe mechanism to prevent cancer or fight it the moment it forms. Otherwise, we wouldn't still be here."Thus began his search for natural molecules coded in the genome that kill cancer."We knew they would be very hard to find," Peter said. "The kill mechanism would only be active in a single cell the moment it becomes cancerous. It was a needle in a haystack."But he found them by testing a class of small RNAs, called small interfering (si)RNAs, scientists use to suppress gene activity. siRNAs are designed by taking short sequences of the gene to be targeted and converting them into double- stranded RNA. These siRNAs when introduced into cells suppress the expression of the gene they are derived from.Peter found that a large number of these small RNAs derived from certain genes did not, as expected, only suppress the gene they were designed against. They also killed all cancer cells. His team discovered these special sequences are distributed throughout the human genome, embedded in multiple genes as shown in the study in Cell Cycle.When converted to siRNAs, these sequences all act as highly trained super assassins. They kill the cells by simultaneously eliminating the genes required for cell survival. By taking out these survivor genes, the assassin molecule activates multiple death cell pathways in parallel.The small RNA assassin molecules trigger a mechanism Peter calls DISE, for Death Induced by Survival gene Elimination.Activating DISE in organisms with cancer might allow cancer cells to be eliminated. Peter's group has evidence this form of cell death preferentially affects cancer cells with little effect on normal cells.To test this in a treatment situation, Peter collaborated with Dr. Shad Thaxton, associate professor of urology at Feinberg, to deliver the assassin molecules via nanoparticles to mice bearing human ovarian cancer. In the treated mice, the treatment strongly reduced the tumor growth with no toxicity to the mice, reports the study in Oncotarget. Importantly, the tumors did not develop resistance to this form of cancer treatment. Peter and Thaxton are now refining the treatment to increase its efficacy.Peter has long been frustrated with the lack of progress in solid cancer treatment."The problem is cancer cells are so diverse that even though the drugs, designed to target single cancer driving genes, often initially are effective, they eventually stop working and patients succumb to the disease," Peter said. He thinks a number of cancer cell subsets are never really affected by most targeted anticancer drugs currently used.Most of the advanced solid cancers such as brain, lung, pancreatic or ovarian cancer have not seen an improvement in survival, Peter said."If you had an aggressive, metastasizing form of the disease 50 years ago, you were busted back then and you are still busted today," he said. "Improvements are often due to better detection methods and not to better treatments."$$!ad_code_content_spilt_video_ad2!$$Cancer scientists need to listen to nature more, Peter said. Immune therapy has been a success, he noted, because it is aimed at activating an anticancer mechanism that evolution developed. Unfortunately, few cancers respond to immune therapy and only a few patients with these cancers benefit, he said."Our research may be tapping into one of nature's original kill switches, and we hope the impact will affect many cancers," he said. "Our findings could be disruptive."
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Learning Physics, Chemistry & Biology (Questions: 71 to 80)

Red Eye Effect - Why do my eyes glow red in photos? Pressure - Why does popcorn pop? Human Nose - Why does spicy food make your nose run? Ignitio
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