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Cancer de la prostate : le rôle préventif de l’éjaculation

Cancer de la prostate : le rôle préventif de l’éjaculation | Prostate cancer | Scoop.it
LA CHRONIQUE DU PR KHAYAT. Une étude conduite auprès de 32.000 hommes suggère une réduction significative du risque de cancer de la prostate, proportionnelle à nombre d'éjaculations.
Hupertan's insight:
Comme tous les études rétrospectives cette étude a beaucoup de biais méthodologiques et donc les résultats sont à prendre avec les précautions d'usage. Par contre sa vulgarisation massive sur les réseaux sociaux sans avertir préalablement les lecteurs fait passé l'info du stade hypothèse probable à celui de certitude scientifique. Comme le Pr Khayat le sait très bien, il n'y a que les l'études prospectives sur un model expérimental qui peuvent prétendre à des résultats suffisamment fiables. Et encore... Et en matière de vie sexuelles, a-t-on besoin des études scientifique?!
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Des indications thérapeutiques actualisées dans l’HBP - L’homme trahi par sa prostate | Le Quotidien du Médecin

Des indications thérapeutiques actualisées dans l’HBP - L’homme trahi par sa prostate | Le Quotidien du Médecin | Prostate cancer | Scoop.it

À 90 ans, 100 % des hommes auront une hypertrophie bénigne de la prostate (HBP). À 60 ans, alors que la prostate a déjà pris du volume chez

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What We're Reading: CMS Wants to Penalize Doctors for Prostate Tests

What We're Reading: CMS Wants to Penalize Doctors for Prostate Tests | Prostate cancer | Scoop.it
What we're reading, November 20, 2015: CMS wants to penalize doctors for ordering routine prostate-cancer screening tests; lawmakers, patients, and advocates call for head of Drug Enforcement Agency to be fired; and specialty drug costs exceed household incomes.
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Yoga may benefit men with prostate cancer, study finds

Yoga may benefit men with prostate cancer, study finds | Prostate cancer | Scoop.it
Men receiving radiation therapy for prostate cancer may find twice-weekly yoga sessions can help maintain life quality and alleviate some side effects, new research suggests.
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European Doctor News - Issue 25 September/October 2015 - Effective use of Firmagon (degarelix) for advanced prostate cancer

European Doctor News - Issue 25 September/October 2015 - Effective use of Firmagon (degarelix) for advanced prostate cancer | Prostate cancer | Scoop.it
For many men with advanced prostate cancer, ADT is an important component of treatment. Degarelix offers rapid reduction of testosterone levels without the risks of an initial surge and remains effective and tolerable over a long period. The concept of a depot subcutaneous injection needs to be clearly understood. The use of a very slow injection technique can improve the patient experience considerably and it is something that should be emphasised to GPs and practice nurses. In addition, patients should be warned about the possibility of injections site reactions, especially with the first dose and advised to use analgesics or cool packs to relieve discomfort.

 

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A positive family history as a risk factor for prostate cancer in a population-based study with organised prostate-specific antigen screening: results of the Swiss European Randomised Study of Scre...

A positive family history as a risk factor for prostate cancer in a population-based study with organised prostate-specific antigen screening: results of the Swiss European Randomised Study of Scre... | Prostate cancer | Scoop.it

Keywords:
prostate cancer screening;positive family history;prostate cancer aggressiveness;prostate-specific antigen;screening intensity
Objective
To assess the value of a positive family history (FH) as a risk factor for prostate cancer incidence and grade among men undergoing organised prostate-specific antigen (PSA) screening in a population-based study.

Subjects and Methods
The study cohort comprised all attendees of the Swiss arm of the European Randomised Study of Screening for Prostate Cancer (ERSPC) with systematic PSA level tests every 4 years. Men reporting first-degree relative(s) diagnosed with prostate cancer were considered to have a positive FH. Biopsy was exclusively PSA triggered at a PSA level threshold of 3 ng/mL. The primary endpoint was prostate cancer diagnosis. Kaplan–Meier and Cox regression analyses were used.

Results
Of 4 932 attendees with a median (interquartile range, IQR) age of 60.9 (57.6–65.1) years, 334 (6.8%) reported a positive FH. The median (IQR) follow-up duration was 11.6 (10.3–13.3) years. Cumulative prostate cancer incidence was 60/334 (18%, positive FH) and 550/4 598 (12%, negative FH) [odds ratio 1.6, 95% confidence interval (CI) 1.2–2.2, P = 0.001). In both groups, most prostate cancer diagnosed was low grade. There were no significant differences in PSA level at diagnosis, biopsy Gleason score or Gleason score on pathological specimen among men who underwent radical prostatectomy between both groups. On multivariable analysis, age (hazard ratio [HR] 1.04, 95% CI 1.02–1.06), baseline PSA level (HR 1.13, 95% CI 1.12–1.14), and FH (HR 1.6, 95% CI 1.24–2.14) were independent predictors for overall prostate cancer incidence (all P < 0.001). Only baseline PSA level (HR 1.14, 95% CI 1.12–1.16, P < 0.001) was an independent predictor of Gleason score ≥7 prostate cancer on prostate biopsy. The proportion of interval prostate cancer diagnosed in-between the screening rounds was not significantly different.

Hupertan's insight:

The conclusion was that 
"Irrespective of the Family History  status, the current PSA-based screening setting detects the majority of aggressive prostate cancers and missed only a minority of interval cancers with a 4-year screening algorithm."

The authors  suggest "that men with a positive Family History are at increased risk of low-grade but not aggressive prostate cancer."

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Prostate Cancer and Men's Health Supplements: MedlinePlus Health News Video

Prostate Cancer and Men's Health Supplements: MedlinePlus Health News Video | Prostate cancer | Scoop.it

Do health supplements marketed using terms like men’s formula and prostate health actually improve the medical outcome of prostate cancer patients?

Hupertan's insight:

The answer is NO: there no arguments to say that the "supplements have harmed patients" 

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Cancer de la prostate (2/3) : causes et symptômes

Interview du Pr. François Haab, chef de service à l'hôpital Tenon à Paris, pour Carenity : causes, symptômes et manifestations du cancer de la prostate.
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La prostate

La prostate uploaded by Cours De Médecine, Cliquez sur j'aime et partagez avec vos ami(e)s . + de videos ou Articles sur http://sh.st/v0qZh.
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Maladies de la prostate - RFI

Maladies de la prostate - RFI | Prostate cancer | Scoop.it
Dans le cadre de la Journée européenne de la Prostate, le 20 septembre 2015, nous dressons un panorama de l’ensemble des maladies de cette glande, à leurs complications éventuelles et aux traitements actuellement disponibles....
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Cancer de la prostate. Tous en slip pour la bonne cause - Le Télégramme

Cancer de la prostate. Tous en slip pour la bonne cause - Le Télégramme | Prostate cancer | Scoop.it
Cancer de la prostate. Tous en slip pour la bonne cause - L'association 3.000 slips a organisé, dimanche, une course dans les rues de la ville au profit de la recherche contre le cancer de la prostate.
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Cancer de la prostate : faut-il se soigner ? - Alternative Santé

Cancer de la prostate : faut-il se soigner ? - Alternative Santé | Prostate cancer | Scoop.it
On dit souvent qu'il est inutile de soigner un cancer de la prostate car l'évolution est tellement lente que le malade a de bonnes chances d'être mort avant que son cancer ne le tue.
Hupertan's insight:

A tous ceux qui se posent la question: "Venez nous accompagner dans nos service, en consultation en réunion de cancérologie!" Vous aurez la réponse.

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Adénome prostatique, que reste-t-il à la chirur...

Adénome prostatique, que reste-t-il à la chirur... | Prostate cancer | Scoop.it

Laser, embolisation, toxine botulique… De nombreuses approches ont été développées pour traiter l’HBP.

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Urology Tag Ontology

Urology Tag Ontology | Prostate cancer | Scoop.it
Urology Tag Ontology
The Urology Tag Ontology's aim is to align hashtag use in the Urological Social Media community. Harnessing this standardized list of Social Media communication descriptors, the project hopes to lower barriers of communication and promote collaboration in the healthcare provider and patient communities.
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Advanced imaging for recurrent PCa: Is the future now?

Advanced imaging for recurrent PCa: Is the future now? | Prostate cancer | Scoop.it
Peter L. Choyke, MDNewer imaging techniques are rapidly changing how recurrent prostate cancer is managed. Peter L. Choyke, MD, chief of molecular imaging at the National Cancer Institute in Bethes
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Soirée de sensibilisation au cancer de la prostate - INFOMAGAZINE PUY-DE-DÔME (Communiqué de presse) (Inscription) (Blog)

Soirée de sensibilisation au cancer de la prostate - INFOMAGAZINE PUY-DE-DÔME (Communiqué de presse) (Inscription) (Blog) | Prostate cancer | Scoop.it
L’ANAMACaP, association nationale des malades du cancer de la prostate, organise Lundi 23 novembre à 18 heures à l’hôtel de Région de Limoges, une soirée de sensibilisation animée par le Professeur François Haab, éminent spécialiste du cancer de la...
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Prevalence of Baseline Erectile Dysfunction (ED) in an Australian Cohort of Men with Localized Prostate Cancer - Ong - 2015 - The Journal of Sexual Medicine - Wiley Online Library

Prevalence of Baseline Erectile Dysfunction (ED) in an Australian Cohort of Men with Localized Prostate Cancer - Ong - 2015 - The Journal of Sexual Medicine - Wiley Online Library | Prostate cancer | Scoop.it

Conclusions
Erectile Dysfunction (ED) is common among patients with localized prostate cancer prior to any curative treatment. Assessment of baseline ED is important prior to curative treatment of prostate cancer in order to offer appropriate advise on likelihood of EF preservation post-treatment and avoid patient dissatisfaction with treatment outcomes due to unrealistic expectations. Ong WL, McLachlan H, and Millar JL. Prevalence of baseline erectile dysfunction (ED) in an Australian cohort of men with localized prostate cancer. J Sex Med 2015;12:1267–1274.

Hupertan's insight:

Assessment of baseline #ED is important prior to curative treatment of #prostatecancer 

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Aligning evidence and practice: future research needs to in... : Current Opinion in Urology

Aligning evidence and practice:  future research needs to in... : Current Opinion in Urology | Prostate cancer | Scoop.it
Aligning evidence and practice: future research needs to increase utilization of active surveillance for favorable risk prostate cancer
Carter, H. Ballentine

Abstract
Purpose of review: The prolonged natural history of prostate cancers detected through prostate-specific antigen-based testing has resulted in many men today undergoing treatment for prostate cancer that will not improve health outcomes. Active surveillance is an underutilized approach to reducing overtreatment of favorable risk prostate cancer. This review outlines the areas for future research that could improve the uptake of active surveillance as a management option.

Recent findings: The reasons for limited uptake of active surveillance for favorable risk prostate cancer are multifactorial and complex. The variability in management of favorable risk disease among older men can be attributed to a greater extent to the individual physician rather than tumor and patient characteristics. Increased uptake of active surveillance will depend on improved risk stratification at diagnosis, surveillance protocol standardization, and patient decision support that accounts for individual patient preferences.

Summary: The disconnect between evidence and practice with respect to management of favorable risk prostate cancer has resulted in overtreatment. Active surveillance as a management option for favorable risk disease may become more acceptable to patients and physicians as research needs are met.
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Robotic Radical Cystectomy Safe, Feasible in the Elderly

Robotic Radical Cystectomy Safe, Feasible in the Elderly | Prostate cancer | Scoop.it
Robotassisted radical cystectomy takes longer than open surgery, but is associated with less blood loss, fewer transfusions, and shorter hospital stays.
Hupertan's insight:

Robot-assisted radical cystectomy (RARC) is a safe and feasible alternative to open radical cystectomy (ORC) in elderly patients, according to a new study.

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L'Angle de l'expert : Facteurs de risque et diagnostic précoce du cancer de prostate

Comprendre votre rapport de pathologie. Thèmes abordés: Nouveaux facteurs de risque y compris les genes BRCA2. Differences majeures entre prévalence, ...
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Cancer de la prostate: passer un test ou pas? - LaPresse.ca

Cancer de la prostate: passer un test ou pas? - LaPresse.ca | Prostate cancer | Scoop.it
LaPresse.ca
Cancer de la prostate: passer un test ou pas?
LaPresse.ca
Passer un test de dépistage précoce du cancer de la prostate plutôt que d'attendre l'apparition de symptômes paraît tout à fait logique.
Hupertan's insight:

Pour ou contre le PSA (le APS) des nos amis canadiens, à l'heure de l'IRM (MRI) multi-paramétrique, est un débat dépassé. PSA c'est un très mauvais test diagnostique mais c'est le meilleur car c'est le seul. L'imagerie par IRM est bien meilleure, avec la possibilité de:

  1. identifier des cibles à biopsies
  2. apprécier la grade d'agressivité
  3. faire un bilan d'extension loco-régionale.

Le couple PSA et IRM, à eux deux diminue le risque de sur-traitement, les biopsies inutiles et de méconnaitre les formes localement avancée.


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Cancer de la prostate : un complément alimentaire à base de brocoli ... - Doctissimo

Cancer de la prostate : un complément alimentaire à base de brocoli ... - Doctissimo | Prostate cancer | Scoop.it
Les news Médicaments Un complément alimentaire à base de sulforaphane, le principe actif du brocoli, pourrait permettre aux hommes atteints d’un cancer de la prostate de retarder le recours à l’hor...
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Auray. Plus de 250 coureurs en slip contre le cancer de la prostate - Ouest-France

Auray. Plus de 250 coureurs en slip contre le cancer de la prostate - Ouest-France | Prostate cancer | Scoop.it
La première édition de la course des "3 000 slips", contre le cancer de la prostate, a eu lieu ce dimanche 20 septembre à Auray. Elle a rassemblé plus de 250
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Le cancer de la prostate, le plus répandu des cancers masculins - Femme Actuelle

Le cancer de la prostate, le plus répandu des cancers masculins - Femme Actuelle | Prostate cancer | Scoop.it
Saviez-vous que plus d'un homme sur neuf développera un cancer de la prostate au cours de sa vie ? En effet, ce type de cancer détient le triste record...
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