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People Around You Control Your Mind

People Around You Control Your Mind | Pasi on This & That | Scoop.it
So you’re sitting on a plane, somewhere in the back. Sweat is rising off this human stew, and in horror you watch it condense, trickling down the window glass. You slam the blind shut. Eww.

Of course the feeling is irrational—you&rsquo...
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How a tiny mutation in the ARHGAP11B gene helped grow our big human brain

How a tiny mutation in the ARHGAP11B gene helped grow our big human brain | Pasi on This & That | Scoop.it

After splitting from the chimpanzee lineage, a single letter of our genome switched to another – and likely shaped the evolutionary expansion of the human.

 

The gene ARHGAP11B promotes basal progenitor amplification and is implicated in neocortex expansion. It arose on the human evolutionary lineage by partial duplication ofARHGAP11A, which encodes a Rho guanosine triphosphatase–activating protein (RhoGAP). However, a lack of 55 nucleotides in ARHGAP11B mRNA leads to loss of RhoGAP activity by GAP domain truncation and addition of a human-specific carboxy-terminal amino acid sequence.

 

Scientists now show that these 55 nucleotides are deleted by mRNA splicing due to a single C→G substitution that creates a novel splice donor site. They reconstructed an ancestral ARHGAP11B complementary DNA without this substitution. Ancestral ARHGAP11B exhibits RhoGAP activity but has no ability to increase basal progenitors during neocortex development. Hence, a single nucleotide substitution underlies the specific properties of ARHGAP11B that likely contributed to the evolutionary expansion of the human neocortex.


Via Dr. Stefan Gruenwald
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Carlos Garcia Pando's comment, December 11, 2016 12:23 PM
Is this a case of progressive evolution? I think this is a clear case of random error: just a sigle base change (C for G) with such a great impact.
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The Science of Happiness: Why Complaining Is Literally Killing You

The Science of Happiness: Why Complaining Is Literally Killing You | Pasi on This & That | Scoop.it
By Steven Parton, From CuriousApes.com Sometimes in life, all the experience and knowledge simmering around in that ol’ consciousness of ours combines itself in a way that suddenly causes the cerebral clockwork to click into place, and...
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The New Science of Happiness

The New Science of Happiness | Pasi on This & That | Scoop.it
A new and blossoming field of psychology - positive psychology - has begun to uncover fascinating, evidence-based answers to many questions about happiness.
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People Around You Control Your Mind

People Around You Control Your Mind | Pasi on This & That | Scoop.it
So you’re sitting on a plane, somewhere in the back. Sweat is rising off this human stew, and in horror you watch it condense, trickling down the window glass. You slam the blind shut. Eww.

Of course the feeling is irrational—you&rsquo...
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10 Mind-Myths: Do Any of These Catch You Out?

10 Mind-Myths: Do Any of These Catch You Out? | Pasi on This & That | Scoop.it
Think our attitudes predict our behaviours? Think we only use 10% of our brains? Think blind people’s other senses are more acute? Think again. Seriously, Would You Admit to Only Using 10% of Your Brain? It’s a nice thought that
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The Riddle of Experience vs. Memory

The Riddle of Experience vs. Memory | Pasi on This & That | Scoop.it
Using examples from vacations to colonoscopies, Nobel laureate and founder of behavioral economics Daniel Kahneman reveals how our "experiencing selves" and our "remembering selves" perceive happiness differently. This new insight has profound implications for economics, public policy -- and our own self-awareness.
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Engagement: The Big Word That Means Very Little

Engagement: The Big Word That Means Very Little | Pasi on This & That | Scoop.it
What the heck does engagement really mean?
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8 Subconscious Mistakes Our Brains Make Every Day - And How to Avoid Them

8 Subconscious Mistakes Our Brains Make Every Day - And How to Avoid Them | Pasi on This & That | Scoop.it
The swimmers body illusion and other ways our brains play tricks on us.
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Debunked: 'Right-Brain' and 'Left-Brain' Personalities

Debunked: 'Right-Brain' and 'Left-Brain' Personalities | Pasi on This & That | Scoop.it
Evidence from over 1,000 fMRI brain scans finds no evidence people are 'right-brained' or 'left-brained'.
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7 Powerful Morning Routines of Mentally Tough People

7 Powerful Morning Routines of Mentally Tough People | Pasi on This & That | Scoop.it
How U.S. Olympians and Navy SEALs start their day off strong (and you can, too).
Pasi Haaponiemi's insight:
7 Powerful Morning Routines of Mentally Tough People
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Your Desk Says What Kind of Genius You Are

Your Desk Says What Kind of Genius You Are | Pasi on This & That | Scoop.it
These 7 famous geniuses had 7 very different workspaces. Based on your desk, what kind of genius might you be?
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Face-Blind. Oliver Sacks opens a window of face-blindness...

Face-Blind. Oliver Sacks opens a window of face-blindness... | Pasi on This & That | Scoop.it
Why are some of us terrible at recognizing faces?
Pasi Haaponiemi's insight:

Oliver Sacks opens a window of face-blindness...

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Mindful! Have a little fun with what's bothering you - a 60-second meditation tool to help you clear your mind

Mindful! Have a little fun with what's bothering you - a 60-second meditation tool to help you clear your mind | Pasi on This & That | Scoop.it
Have a little fun with what's bothering you. Take 60 seconds to try Pixel Thoughts.
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Key Behavioral Catchphrases - How to Explain Mood, Bias and the Dark Triad...

Key Behavioral Catchphrases - How to Explain Mood, Bias and the Dark Triad... | Pasi on This & That | Scoop.it
Cool ideas in the quest to understand behavior.
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10 Research-Based Truths About People in Love

10 Research-Based Truths About People in Love | Pasi on This & That | Scoop.it
What we've learned so far about love and the brain.
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Let It Go!

Let It Go! | Pasi on This & That | Scoop.it
Past hurts and old injustices have a way of keeping us stuck in our tracks, unable to move forward or experience joy. It can take a radical reboot to get past yesterday. Here's how.
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Growth Hacker: A Buzzword Surrounded by Buzzwords

Growth Hacker: A Buzzword Surrounded by Buzzwords | Pasi on This & That | Scoop.it
Yes, Growth Hacker is an enormously overwrought buzzword. But, companies are sorely looking for people to take up the mantle and work on startup marketing.
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The 12 Most Overused Business Buzzwords

The 12 Most Overused Business Buzzwords | Pasi on This & That | Scoop.it
Does anyone actually like business jargon, or is it just a bad habit? Found in corporate offices, startups and resumes alike, business buzzwords and phrases like "think outside ...
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The Psychological Pain of Losing $100 is Much Greater Than the Joy of Gaining $100

The Psychological Pain of Losing $100 is Much Greater Than the Joy of Gaining $100 | Pasi on This & That | Scoop.it
The evolved wisdom behind our seemingly stupid decisions
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