Parkinson's disease and serotonin
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Les espoirs de Neurolixis dans la recherche sur la maladie de Parkinson

La société Neurolixis pilotée à Castres par Adrian Newman-Tancredi, ancien chercheur chez Pierre-Fabre, vient de lever 1 million de dollars afin de poursuivre la recherche sur une molécule très prometteuse dans le traitement du Parkinson. C'es
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Parkinson's UK awards 1M$ grant to Neurolixis

Parkinson's UK awards 1M$ grant to Neurolixis | Parkinson's disease and serotonin | Scoop.it
Parkinson's UK is partnering with US company Neurolixis to accelerate the development of a promising new drug that could prevent dyskinesia, one of the most debilitating side effects of Parkinson's medication.
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Distinctive in vitro signal transduction profile of NLX-112, a potent and efficacious serotonin 5-HT1A receptor agonist - Newman-Tancredi - 2017 - Journal of Pharmacy and Pharmacology

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Conversion of brain cells offers hope for Parkinson’s patients

Researchers at Karolinska Institutet have made significant progress in the search for new treatments for Parkinson’s disease.
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FDA approves drug as add-on remedy for Parkinson's illness sufferers - Medicalnewser.com

FDA approves drug as add-on remedy for Parkinson's illness sufferers - Medicalnewser.com | Parkinson's disease and serotonin | Scoop.it
March 21, 2017 at 10:42 PM The U.S. Meals and Drug Management these days licensed Xadago (safinamide) capsules as an add-on remedy for sufferers with
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FDA OKs Pimavanserin for Hallucinations in Parkinson's

FDA OKs Pimavanserin for Hallucinations in Parkinson's | Parkinson's disease and serotonin | Scoop.it
First drug approved for this indication
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Serotonin 5-HT1A Receptors on Astrocytes as a Potential Target for Treatment of Parkinson's Disease.

Serotonin 5-HT1A Receptors on Astrocytes as a Potential Target for Treatment of Parkinson's Disease. | Parkinson's disease and serotonin | Scoop.it
Curr Med Chem. 2016 Jan 21. [Epub ahead of print]
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Scientists discover why levodopa can lead to dyskinesia

Scientists discover why levodopa can lead to dyskinesia | Parkinson's disease and serotonin | Scoop.it
Researchers have discovered why long-term use of levodopa, a treatment for Parkinson's disease, commonly leads to a movement problem called dyskinesia.
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Neurolixis Showcased in The Michael J. Fox Foundation’s Partnering Program | PRLog

Neurolixis Showcased in The Michael J. Fox Foundation’s Partnering Program | PRLog | Parkinson's disease and serotonin | Scoop.it
Neurolixis Showcased in The Michael J. Fox Foundation’s Partnering Program. Neurolixis today announced that it had been selected by The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to be showcased in its Partnering Program.

Via Neurolixis
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Adamas Pharmaceuticals Receives Orphan Drug Designation for ADS-5102 for ... - MarketWatch

Adamas Pharmaceuticals Receives Orphan Drug Designation for ADS-5102 for ... - MarketWatch | Parkinson's disease and serotonin | Scoop.it
Nasdaq
Adamas Pharmaceuticals Receives Orphan Drug Designation for ADS-5102 for ...
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Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study

Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study | Parkinson's disease and serotonin | Scoop.it
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Taking a Stem Cell Shot at Parkinson’s Disease

Taking a Stem Cell Shot at Parkinson’s Disease | Parkinson's disease and serotonin | Scoop.it

Can dopaminergic cells derived from stem cells reverse Parkinson's disease? - Neuroscience News

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L-DOPA treatment correlates with increased Depressive Symptoms in Parkinson's Disease

Depressive symptoms are very common in patients with Parkinson’s disease and have a significant impact on the quality of life. The results of this study show that in patients with PD, higher l-DOPA dosages correlate with worse depressive symptoms. 

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A Castres, Neurolixis à la pointe de la recherche sur le traitement de la maladie de Parkinson

A Castres, Neurolixis à la pointe de la recherche sur le traitement de la maladie de Parkinson | Parkinson's disease and serotonin | Scoop.it
La société américaine Neurolixis, dont la branche européenne est sise à Castres, a reçu pour ses recherches, en partie menées dans le Tarn, sur une molécule qui pourrait soulager les personnes atteintes de Parkinson, près d'un million de dollars de la fondation britannique Parkinson's UK.
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Antinociceptive, antiallodynic and antihyperalgesic effects of the 5-HT1A receptor selective agonist, NLX-112 in mouse models of pain. - PubMed - NCBI

Antinociceptive, antiallodynic and antihyperalgesic effects of the 5-HT1A receptor selective agonist, NLX-112 in mouse models of pain. - PubMed - NCBI | Parkinson's disease and serotonin | Scoop.it
Neuropharmacology. 2017 Jul 24;125:181-188. doi: 10.1016/j.neuropharm.2017.07.022. [Epub ahead of print]
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ScientificAnimations's comment, December 26, 2017 5:35 AM
Parkinson’s Disease: The fastest growing neurological disorder - http://sco.lt/9J2aVl
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Researchers identify biomarkers that may predict cognitive impairment

Researchers identify biomarkers that may predict cognitive impairment | Parkinson's disease and serotonin | Scoop.it

New biomarkers identified by a research team in the Perelman School of Medicine at the University of Pennsylvania could help predict which Parkinson's disease patients will suffer significant cognitive deficits

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Michael J Fox 'can't stop laughing' at his Parkinson's disease symptoms

Michael J Fox 'can't stop laughing' at his Parkinson's disease symptoms | Parkinson's disease and serotonin | Scoop.it

The Back To The Future actor was diagnosed with the illness 26 years ago.
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Serotonin transporter in Parkinson's disease: A meta‐analysis of positron emission tomography studies

Serotonin transporter in Parkinson's disease: A meta‐analysis of positron emission tomography studies | Parkinson's disease and serotonin | Scoop.it
Positron emission tomography (PET) is a powerful analytical tool for in vivo molecular imaging of the human brain. Over the past years, a number of PET studies imaging the serotonin transporte
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22 February 2016 - Just Published: articles on NLX-112 in models of dyskinesia in Parkinson's disease

22 February 2016 - Just Published: articles on NLX-112 in models of dyskinesia in Parkinson's disease | Parkinson's disease and serotonin | Scoop.it
neurolixis joomla3
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Dyskinesia Drug a Step Closer to FDA Approval with Positive Phase III Results

Dyskinesia Drug a Step Closer to FDA Approval with Positive Phase III Results | Parkinson's disease and serotonin | Scoop.it

Adamas has announced positive Phase III results for its treatment for dyskinesia, involuntary movements that are a side effect of levodopa use. Such a therapy could impact how we treat motor symptoms.

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Putaminal serotonergic innervation flags levodopa-induced dyskinesia risk - News-Medical.net

Putaminal serotonergic innervation flags levodopa-induced dyskinesia risk - News-Medical.net | Parkinson's disease and serotonin | Scoop.it
Increased serotonergic fibre innervation relative to dopaminergic fibre availability may be a potential marker of disease progression in Parkinson’s disease patients and a possible warning of levodopa-induced dyskinesia, indicates an in vivo...
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NLX-112, a novel 5-HT1A receptor agonist for the treatment of L-DOPA-induced dyskinesia: Behavioral and neurochemical profile in rat.

NLX-112, a novel 5-HT1A receptor agonist for the treatment of L-DOPA-induced dyskinesia: Behavioral and neurochemical profile in rat. | Parkinson's disease and serotonin | Scoop.it

Published in: Experimental Neurology. 2015 May 30. pii: S0014-4886(15)30008-X. doi: 10.1016/j.expneurol.2015.05.021. [Epub ahead of print]

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Michael J. Fox Foundation Announces New Funding for Alzheimer's, Parkinson's ... - Bioscience Technology

Michael J. Fox Foundation Announces New Funding for Alzheimer's, Parkinson's ... - Bioscience Technology | Parkinson's disease and serotonin | Scoop.it
Michael J. Fox Foundation and Alzheimer’s Association fund $2 million for research projects studying overlap in neurodegenerative diseases.
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Presynaptic Effects of Levodopa at Serotonin Neurons and Their Possible Role in Dyskinesia - Movement Disorders - 2014

Presynaptic Effects of Levodopa at Serotonin Neurons and Their Possible Role in Dyskinesia - Movement Disorders - 2014 | Parkinson's disease and serotonin | Scoop.it
RT @movedisorder: Presynaptic Effects of Levodopa and Their Possible Role in Dyskinesia http://t.co/wx70NRNt6i
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Tony Mendez, real-life 'Argo' CIA hero, reveals he has Parkinson's disease - Today.com

Tony Mendez, real-life 'Argo' CIA hero, reveals he has Parkinson's disease - Today.com | Parkinson's disease and serotonin | Scoop.it
Tony Mendez, the retired CIA agent played by Ben Affleck in the hit movie "Argo,'' has revealed that he is battling Parkinson's disease. ...
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