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A Grab Bag of OVCA Info
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Home - GTR - NCBI

The Genetic Testing Registry (GTR) provides a central location for voluntary submission of genetic test information by providers.
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Foundation Medicine: Personalizing Cancer Drugs - Technology Review

Foundation Medicine: Personalizing Cancer Drugs - Technology Review | ovarian cancer | Scoop.it
Foundation Medicine is offering a test that helps oncologists choose drugs targeted to the genetic profile of a patient's tumor cells. Has personalized cancer treatment finally arrived?
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Phase I clinical trials for dendritic cell vaccine designed to both eradicate cancer cells and prevent disease relapse

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Does wait-see work in high-risk cases? - Palm Beach Post

Does wait-see work in high-risk cases? - Palm Beach Post | ovarian cancer | Scoop.it
Does wait-see work in high-risk cases?Palm Beach PostBy Dr. Melanie Bone Dear Dr. Bone: When a patient is at high risk for breast and ovarian cancer, do you recommend vigilance or an aggressive approach?
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Ovarian Cancer

http://www.cancernetwork.com/cancer-management/ovarian/article/10165/1802681

This chapter will focus on epithelial cancers of the ovaries, which account for about 90% of ovarian malignancies.

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Refadoc.com's curator insight, September 11, 2014 6:36 AM

Ovarian Cancer, as is evident from the name is the one which affects the ovaries of the affected person. Women have a pair of ovaries on every side of the uterus. Every ovary, which is the size of an almond produce the eggs as well as the hormones by the name of the estrogens as well as progesterone. In most of the cases, ovarian cancer goes on to remain undetected until it has been spread well between the pelvic and the abdomen of the affected person. In the later stages, the cancer becomes very hard to treat and can prove out to be very fatal as well. In the early stages of the cancer, the disease is restricted only to the ovaries of the person and can be treated very easily. Mostly, surgeries as well as chemotherapy are the most commonly chosen ways for the treatment of the disease.

Causes of Ovarian Cancer:

The real cause of the Ovarian Cancer is not known. The cancer tends to begin with the genetic mutation and this makes the normal cells to turn to abnormal cells. The cells begin to multiply very easily, and then this leads to the creation of the tumour. Also, then these abnormal cells go on to invade all the nearby tissues and therefore, start breaking off from the initial tumour and therefore spread to other parts of the body. This is known as metastasizes. Some of the major types of the ovarian cancer are as follows:

Epithelial Tumours: These begin with the thin layers of the tissue that start outside the ovaries of the affected person. Also, about 90% of cancers are of this type only.Stromal Tumours: These tend to begin at the ovarian tissues and are the ones which contain hormone producing cells. Also, these tumours are diagnosed at the easiest stage as compared to the ovarian tumours. About 7% of the cancers are stromal cells.Germ Cell Tumours: These begin at the egg producing cells. These are very rare kinds of ovarian cancers and therefore, tend to begin in the younger women as compared to the older ones.http://www.refadoc.com/post/ovarian-cancer- Signs and Symptoms of Ovarian Cancers:

At the earlier stage of the Ovarian Cancer, there are hardly any signs and symptoms which make the detection of the disease very difficult. In the advanced stage however, the causes and the symptoms tend to be very few and very non specific and therefore can be mistaken into some other signs for the benign conditions, such as constipation and even irritability of the bowels. Some of the major signs and symptoms are as follows:

o   Bloating and swelling in the abdomen

o   A feeling of being full after eating little quantity of food

o   Loss of weight

o   Discomfort in the pelvic area

o   Changing in the bowel habits, such as constipation

o   A frequent need for urination

If you have these above mentioned signs and symptoms, then it is recommended to see a doctor regarding that at the soonest. For ovarian cancer, if the risk runs in the family, then the chances of the occurrence of cancer is manifold. A small volume of women all over the world are the ones which have genetic mutations which lead to ovarian cancer.

http://www.refadoc.com/post/ovarian-cancer- ;

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OVARIAN CANCER and US: abstract: Extraperitoneal metastases from recurrent ovarian cancer. (study n=233 women) eg. lung, CNS, pulmonary, skin (cutaneous)

OVARIAN CANCER and US: abstract: Extraperitoneal metastases from recurrent ovarian cancer. (study n=233 women) eg. lung, CNS, pulmonary, skin (cutaneous) | ovarian cancer | Scoop.it

CONCLUSIONS:

Extraperitoneal recurrences were more common in women treated with IP chemotherapy for ovarian cancer. Specifically, women treated with IV BEV as secondary therapy after IP were at particularly high risk of extraperitoneal metastases, including in the CNS and cutaneous tissues. Physicians should be aware of the possibility of unusual metastases after the combination of IP chemotherapy and BEV, and future prospective studies of this population should carefully evaluate recurrence site patterns.

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Triptorelin Reverses Cisplatin Resistance in Human Ovarian Carcinoma Cell Line (OVCAR-3) via EGFR Signal Pathway Archive - Cancer Research Center

Triptorelin Reverses Cisplatin Resistance in Human Ovarian Carcinoma Cell Line (OVCAR-3) via EGFR Signal Pathway Archive - Cancer Research Center | ovarian cancer | Scoop.it
Introduction At present,chemotherapy is one of the primary modalities for the treatment of ovarian carcinoma.The cisplatin is one of the most effective anticancer drugs.However, the acquired resistance to cisplatin is one of the most significant reasons...
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National Cancer Institute

BRCA1 and BRCA2: Cancer Risk and Genetic Testing

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FDA OKs drug to eliminate chemotherapy side effect - Sacramento Bee

FDA OKs drug to eliminate chemotherapy side effect - Sacramento Bee | ovarian cancer | Scoop.it
MedCity NewsFDA OKs drug to eliminate chemotherapy side effectSacramento BeeAP WASHINGTON -- The Food and Drug Administration says it approved a drug to reduce dangerous levels of a certain chemotherapy drug in cancer patients with failing kidneys.
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Researcher Blueprints Ovarian Cancer Tumors (VIDEO)

Researcher Blueprints Ovarian Cancer Tumors (VIDEO) | ovarian cancer | Scoop.it
Ovarian cancer is called a silent killer because, by the time symptoms appear and diagnosis is made, it is generally too late for a cure. Last year, 22,000 women were diagnosed with the disease in the United States; 14,000 of them died.
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Faulty proteins help identify new treatments for ovarian cancer - The Virtual Medical Centre

Faulty proteins help identify new treatments for ovarian cancer - The Virtual Medical Centre | ovarian cancer | Scoop.it
The Virtual Medical CentreFaulty proteins help identify new treatments for ovarian cancerThe Virtual Medical CentrePejovic, who led the study of these additional defective proteins, added that the results provide evidence that further research into...
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Medical News:Advanced Ovarian Cancer -- A Clinical Context Report - in Clinical Context, Ovarian Cancer from MedPage Today

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What's Behind Our National Drug Shortages?

What's Behind Our National Drug Shortages? | ovarian cancer | Scoop.it
It's easy to understand why millions of patients with cancer, infections, heart disease, central nervous system conditions and pain get riled up when they learn there are shortages of drugs for what ails them.
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FDA-Approved Ovarian Cancer Drug Treatments - Chemotherapy Advisor

Medications used to treat ovarian cancer.
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OVARIAN CANCER and US: UH Case Medical Center Offers New Therapy (HIPEC) for Gynecologic Cancer Patients -- CLEVELAND, Jan. 20, 2012 /PRNewswire/

OVARIAN CANCER and US: UH Case Medical Center Offers New Therapy (HIPEC) for Gynecologic Cancer Patients -- CLEVELAND, Jan. 20, 2012 /PRNewswire/ | ovarian cancer | Scoop.it

CLEVELAND, Jan. 20, 2012 /PRNewswire/ -- Patients with gynecologic cancer have new hope in a novel technology now offered at the Seidman Cancer Center at University Hospitals (UH) Case Medical Center. A team of cancer specialists, led by Robert DeBernardo, MD, is among the first in the nation to launch a dedicated program using Hyperthermic Intraperitoneal Chemotherapy (HIPEC) to treat ovarian, endometrial and select other cancers....."

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OVARIAN CANCER and US: open access: Review - 2010 Targeted Therapies in Epithelial Ovarian Cancer

OVARIAN CANCER and US: open access: Review - 2010 Targeted Therapies in Epithelial Ovarian Cancer | ovarian cancer | Scoop.it
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Genetics of Breast and Ovarian Cancer (PDQ®) - National Cancer Institute

Expert-reviewed information summary about the genetics of breast and ovarian cancer, including information about specific genes and family cancer syndromes.
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Ovarian Cancer Home Page - National Cancer Institute

Information about ovarian cancer treatment, prevention, genetics, causes, screening, clinical trials, research and statistics from the National Cancer Institute.
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Tumor-Freezing Treatment Gives Ovarian Cancer Patients Extra Time: Presented ... - MarketWatch (press release)

Tumor-Freezing Treatment Gives Ovarian Cancer Patients Extra Time: Presented ... - MarketWatch (press release) | ovarian cancer | Scoop.it
Tumor-Freezing Treatment Gives Ovarian Cancer Patients Extra Time: Presented ...MarketWatch (press release)MIAMI BEACH, Fla., Jan 15, 2012 (BUSINESS WIRE) -- Killing tumors by freezing them through cryoablation can extend the lives of women with ovarian...
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OVARIAN CANCER and US: abstract: Extraperitoneal Metastases ...

OVARIAN CANCER and US: abstract: Extraperitoneal Metastases ... | ovarian cancer | Scoop.it
Conclusions: Extraperitoneal recurrences were more common in women treated with IP chemotherapy for ovarian cancer. Specifically, women treated with IV BEV as secondary therapy after IP were at particularly high risk of ...
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Baylor scientists receive $1.35 million from Ovarian Cancer Research Fund - Baylor College of Medicine

http://t.co/qb8Rkee0 Baylor scientists receive $1.35 million from Ovarian Cancer Research Fund - BCM News...
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