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Genomics: The DNA of Precision Medicine Do you work in the lab or are you involved in sequencing? There's over 3 billion reasons your genes make you unique
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GEN | News Highlights:GBSI: Standardize Preclinical Research to Suppress Irreproducible Results

GEN | News Highlights:GBSI: Standardize Preclinical Research to Suppress Irreproducible Results | Oncology | Scoop.it
Report on life sciences research quality bemoans problem of irreproducibility and calls for the development of standards to guide research from the bench to the patient.
Brian Burke's insight:

Biology has been allowed to make excuses for lack of quantification for too long.  As this article rightly states, greater efforts need to be made in delivering quality, reproducible science so that scientific discovery and translation can be acheived in an effective manner.

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Illumina .::. Investor Relations News Release

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NGS platforms have transitioned to clinical applications quicker than any other llfe science platform in recent history.  Acheiving any sort of FDA approval for such a platform is a first and bodes well for future developments in the oncology area.

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The Quest to Overcome Resistance to EGFR-Targeted Therapies in Cancer

The Quest to Overcome Resistance to EGFR-Targeted Therapies in Cancer | Oncology | Scoop.it

Despite the initial promise of cancer therapies targeted against the epidermal growth factor receptor (EGFR), tumors treated with these agents eventually develop resistance.


Via Cancer Commons
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"Cancer is like a multi-headed hydra...."  Best description of cancer to date in my view. More has to be done to educate the public on what "cancer" really is and what the expectations are for treatment. 

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Cancer Commons's curator insight, November 11, 2013 12:14 PM

Chong CR and Janne PA. Nature Medicine. Nov 7, 2013.

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This is real innovation: Illumina's new machine could slash cost of sequencing your genome to $1,000

This is real innovation: Illumina's new machine could slash cost of sequencing your genome to $1,000 | Oncology | Scoop.it
Biotech firm Illumina sent shockwaves through the genetics industry this week by announcing a new machine that, it says, will allow companies to sequence the human genome for $1,000.
Brian Burke's insight:

It's amazing to think that something that cost $100M less than 15 years ago can now be delivered in a fraction of the time for something between $1000 and $5000.  This has significant implications for healthcare providers and patients and arguably represents the first real milestone towards translating personlised healthcare into reality that is available to the average person.

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The FDA Is Poised to Kill the Personal Genetics Testing Industry

The FDA Is Poised to Kill the Personal Genetics Testing Industry | Oncology | Scoop.it
The Food and Drug Administration’s recent directive to the company 23andMe to stop marketing its genetic tests directly to consumers is a shortsighted, heavy-handed, double-standard act of paternalism.
Brian Burke's insight:

Very fair article challenging the notion that the FDA or doctors are the best placed to decide what should be done with genetic information. 

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'Vicious cycle' shields, spreads cancer cells - Toronto NewsFIX

'Vicious cycle' shields, spreads cancer cells - Toronto NewsFIX | Oncology | Scoop.it
'Vicious cycle' shields, spreads cancer cells
Toronto NewsFIX
Carson described EGFR as a powerful transmembrane protein that stimulates normal cell growth, proliferation and differentiation.
Brian Burke's insight:

Nice article illustrating in laymans terms the real challenges of
"fighting cancer"...

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