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MS Research Highlights In 2014 That Offer New Leads In Stopping MS, Restoring Function Lost, And Ending MS Forever

MS Research Highlights In 2014 That Offer New Leads In Stopping MS, Restoring Function Lost, And Ending MS Forever | Multiple sclerosis | Scoop.it
In 2014, the National Multiple Sclerosis Society invested $50.6 million in 380 new and ongoing research projects and initiatives. Here is a brief summary of the research highlights reflecting the Society’s commitment to pursue promising opportunities wherever they exist, while focusing on three priority areas: progressive MS, nervous system repair, and wellness/lifestyle, which have been singled out under each research goal below when applicable.

Via Krishan Maggon
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New Drug Shows Promise for Progressive Form of MS

New Drug Shows Promise for Progressive Form of MS | Multiple sclerosis | Scoop.it

In a phase 2 clinical trial, an investigational anti-inflammatory drug called ibudilast was found to be superior to placebo in slowing the progression of brain atrophy in patients with progressive multiple sclerosis. The study, conducted at 28 sites around the country, including Columbia University Irving Medical Center, was published last month in the New England Journal of Medicine.

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I would love nothing more than to punch multiple sclerosis in the face

I would love nothing more than to punch multiple sclerosis in the face | Multiple sclerosis | Scoop.it

When you see me, you may see my hair fixed up nicely, my makeup looking flawless, my clothes neatly pressed and my shoes coordinating with my purse. I may have everything in place from head to toe including the smile I put on and the positive attitude I carry.

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ITALY, Milan - San Raffaele: Stem Cells Aid in the Regrowing of Nerves

ITALY, Milan - San Raffaele: Stem Cells Aid in the Regrowing of Nerves | Multiple sclerosis | Scoop.it

A biopolymer could aid in the regrowing of nerves induced by the use of stem cells according to a new research project that gives hope to people who have been in an accident and have lost the use of one or more limbs. The procedure will enter into clinical testing in January after animal testing has been completed.

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Stem cell transplants are a 'game changer' for MS patients

Stem cell transplants are a 'game changer' for MS patients | Multiple sclerosis | Scoop.it
  • More than 100 patients with a common form of MS were involved in the study 
  • They were either given a stem cell transplant or were given conventional drugs
  • The £30,000 treatment involves flooding the immune system with cancer drugs
  • The immune system is then rebooted with stem cells from the MS patient's blood
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That "Game Changer" Treatment for MS Is Too Good To Be True — Really

That "Game Changer" Treatment for MS Is Too Good To Be True — Really | Multiple sclerosis | Scoop.it

A new treatment for the chronic and debilitating disease multiple sclerosis (MS) has doctors throwing around phrases like “game changer.” Newsweek said it could “revolutionize care for one million Americans.” Alphr called it a “breakthrough.”

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Alemtuzumab stops working. I wonder why?

Alemtuzumab stops working. I wonder why? | Multiple sclerosis | Scoop.it
Alemtuzumab, a highly effective treatment for relapsing remitting multiple sclerosis (RRMS), induces lymphopenia especially of CD4+ T cells. Here, we report the atypical CD4+ T population behaviour of two patients with persistent disease activity despite repeated alemtuzumab treatments.
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Taurine Enhances Remyelination In Multiple Sclerosis Damage

Taurine Enhances Remyelination In Multiple Sclerosis Damage | Multiple sclerosis | Scoop.it

Taurine helps spark a process called remyelination, which is crucial to repairing the nerve cells damaged in multiple sclerosis, new research from scientists at The Scripps Research Institute has found.
The results suggest that administering taurine, a molecule naturally produced by human cells, could boost the effectiveness of current multiple sclerosis (MS) therapies.

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Red Bull to be soon reimbursed?...

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Serum Biomarker May Predict Relapse in MS

Serum Biomarker May Predict Relapse in MS | Multiple sclerosis | Scoop.it
High NF-L levels could identify subclinical disease activity
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PLEGRIDY® (peginterferon beta-1a)

PLEGRIDY® (peginterferon beta-1a) | Multiple sclerosis | Scoop.it
These videos are all about what it’s like to treat your relapsing MS with PLEGRIDY. In them you’ll find the stories of real PLEGRIDY patients and Nurse Educators from Biogen, plus tips, anecdotes, and insights about living with relapsing MS.
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New Gene Therapy Could Reverse Paralysis in Multiple Sclerosis

New Gene Therapy Could Reverse Paralysis in Multiple Sclerosis | Multiple sclerosis | Scoop.it
Multiple Sclerosis (MS) is an autoimmune disease in the central nervous system that affects the brain and spinal cord. When someone has MS, their immune system thinks that myelin is a foreign body and begins attacking the protective sheath.
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Multiple Sclerosis Travel Insurance at World First

Multiple Sclerosis Travel Insurance at World First | Multiple sclerosis | Scoop.it
At World First we know that Multiple Sclerosis is almost always no reason to stop you enjoying a happy holiday. That's why we have no quibbles offering our range of comprehensive travel insurance policies to those living with the condition. And they all come with the policy features you need for peace of mind and a hassle-free break.
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Multiple sclerosis, discovered at San Raffaele a protein-drug released from stem cells

Stem cell transplantation in the brain of patients with progressive multiple sclerosis reduces inflammation by the release of a protein-drug. It is the important discovery accomplished by the researchers of the San Raffaele Hospital, who in late May started the first clinical study in the world for the treatment of the pathology with the so-called "stems" therapy. A first group of three patients successfully completed the first cycle of low-dose neural stem treatment.
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Preparing for an MS Flare

Preparing for an MS Flare | Multiple sclerosis | Scoop.it
The most common form of multiple sclerosis (MS), called relapsing-remitting MS, can feel like a tug of war between flares and periods of remission. Adding to this frustration, MS flares can be unpredictable.
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In Mice with MS, Small Molecule TDP6 Activates Myelin Regeneration

In Mice with MS, Small Molecule TDP6 Activates Myelin Regeneration | Multiple sclerosis | Scoop.it

The hallmark of MS is the immune system’s destruction of myelin, the coating that surrounds nerve cell axons (the long threadlike part of a nerve cell) and, much like the insulation around electrical wires, protects the axons and allows the firing of signals between nerve cells or between nerve cells and effector cells, like those in the muscles.

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New Drug Shows Promise For Patients With Progressive Multiple Sclerosis

New Drug Shows Promise For Patients With Progressive Multiple Sclerosis | Multiple sclerosis | Scoop.it

A new drug for Multiple Sclerosis is showing promise. A study shows the experimental drug, called Ibudilast, slowed brain atrophy or shrinkage by almost 50%. The study, funded by the National Institutes of Health and authored by Dr. Claire Riley, involved 255 MS patients at 28 centers around the country.

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Understanding the Different Types of Multiple Sclerosis

Understanding the Different Types of Multiple Sclerosis | Multiple sclerosis | Scoop.it
Did you know that there are four basic types of MS, each affecting patients in unique ways? Here’s what to expect from the different kinds of MS.
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A stem-cell treatment shows promise fighting multiple sclerosis

A stem-cell treatment shows promise fighting multiple sclerosis | Multiple sclerosis | Scoop.it
Chemotherapy is used to destroy a patient’s faulty immune system. Then stem cells from the patient’s blood and bone marrow are infused to help rebuild it. The approach is being used to treat relapsing remitting MS, where patients have spells without symptoms before succumbing to the illness again.
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Potential Path to Repair Nerves Damaged by Multiple Sclerosis

Potential Path to Repair Nerves Damaged by Multiple Sclerosis | Multiple sclerosis | Scoop.it
Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking.
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Tested: A Reboot for the Immune System

Tested: A Reboot for the Immune System | Multiple sclerosis | Scoop.it
A sign rests on the windowsill in the office of Jeffrey Bluestone, director of the Immune Tolerance Network and the Diabetes Center at the University of California at San Francisco. Measuring nearly three feet across, it reads "Club Bluestone" in pink and blue neon. It's the sort of artifact you'd expect to find in a bar.
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A New Vaccine Against Multiple Sclerosis

A New Vaccine Against Multiple Sclerosis | Multiple sclerosis | Scoop.it
An experimental DNA vaccine against multiple sclerosis (MS) appears safe in early human tests and shows signs of effectiveness, according to a paper published Monday in the online version of the Archives of Neurology.
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A 'glitch' in T cell development sheds light on MS

A 'glitch' in T cell development sheds light on MS | Multiple sclerosis | Scoop.it
Regulatory T cells play an important role in the immune system: They rein in wayward T cells that attack normal tissues in the body, causing autoimmune diseases like multiple sclerosis. Now a University of Edinburgh-led team has uncovered a mechanism in multiple sclerosis that prevents regulatory T cells from developing.
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Stem Cell Research and MS - Multiple Sclerosis

Stem Cell Research and MS - Multiple Sclerosis | Multiple sclerosis | Scoop.it
Stem cell therapy is an exciting area of multiple sclerosis research. Interest in the potential of stem cells to improve multiple sclerosis by slowing down the disease and repairing damage to the nervous system continues to grow in the MS research community. However, it can be confusing to know what is discussed when “stem cells” are mentioned in the news or scientific publications.
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How Close Are We to a Cure For MS?

How Close Are We to a Cure For MS? | Multiple sclerosis | Scoop.it
Every day in Australia, two people are diagnosed with multiple sclerosis — and if you ask us, that's two too many! In our quest to find out more about the relatively hard-to-diagnose disease, that commonly affects women in their 30s, we asked Dr. Hamish Campbell, the research development coordinator at MS Research Australia, to tell us how close researchers are to finding a cure for the debilitating condition.
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Mylan's MS Generic High-dose Version of Copaxone Wins FDA Approval

Mylan's MS Generic High-dose Version of Copaxone Wins FDA Approval | Multiple sclerosis | Scoop.it
Generic versions of the lower dose of 20 mg/mL — intended for daily injections — have been around for some time. The FDA approval covers both Mylan’s higher dose of 40 mg/mL of glatiramer acetate and the lower dose. Those using the higher dose will be able to reduce their injections to three times per week.
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Bryan Bickell Retires With Blackhawks On One-Day Contract After Multiple Sclerosis Diagnosis

Bryan Bickell Retires With Blackhawks On One-Day Contract After Multiple Sclerosis Diagnosis | Multiple sclerosis | Scoop.it
Nearly a year after he first announced that he’d been diagnosed with multiple sclerosis, Bryan Bickell signed a one-day contract this week to retire as a Chicago Blackhawk. After hosting a retirement press conference yesterday, he got one last chance to head out on the ice tonight, in a special pre-game ceremony that got a standing ovation from fans.
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