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Rescooped by Franc Viktor Nekrep from Viruses, Immunology & Bioinformatics from Virology.uvic.ca
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New flu gene found hiding in plain sight, and affects severity of infections | Not Exactly Rocket Science | Discover Magazine

New flu gene found hiding in plain sight, and affects severity of infections | Not Exactly Rocket Science | Discover Magazine | mikrobiologija | Scoop.it

"The new gene that Jagger discovered is another double-dip. It’s found in the virus’ third RNA strand, which was traditionally thought to only contain the PA gene. PA helps the virus copy its genome. Jagger first noticed something weird about the gene when he found that one part of it was incredibly similar across different flu strains. Flu evolves at a breakneck pace, so any island of constancy amid this sea of change must mean something. Jagger discovered that this conserved region contains a second gene called PA-X."


Via Jeff Habig
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TWiV 187: The mummy

TWiV 187: The mummy | mikrobiologija | Scoop.it
Vincent and Rich discuss recovery of a hepatitis B viral genome from a 16th century Korean mummy, and personal omics profiling.

Via Chris Upton + helpers
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Base By Base | A multiple alignment editor (with lots of analysis features)

Base By Base | A multiple alignment editor (with lots of analysis features) | mikrobiologija | Scoop.it

Base-By-Base is a whole genome pairwise and multiple alignment editor. The program highlights differences between pairs of alignments and allows the user to easily navigate large alignments of similar sequences. Although Base-By-Base was intended as an editor and viewer for alignments of highly similar sequences, it is also provides many of the functions of other generic alignment editors.


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The Tree of Life: 'Danger and Evolution in the Twilight Zone': Guest ...

The Tree of Life: 'Danger and Evolution in the Twilight Zone': Guest ... | mikrobiologija | Scoop.it
I have been communicating with Randen Patterson on and off over the last five years or so about his efforts to try and study the evolution of gene families when the sequence similarity in the gene family is so low that making ...
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Rescooped by Franc Viktor Nekrep from Plants and Microbes
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EPA Factsheet: Puccinia thlaspeos strain woad (dyer's woad rust)

EPA Factsheet: Puccinia thlaspeos strain woad (dyer's woad rust) | mikrobiologija | Scoop.it

Dyer's woad rust (Puccinia thlaspeos 'strain woad') is used as a pesticide to control the spread of dyer's woad, an invasive weed in the dry open areas of eight western states. Rusts are a group of fungi that infect only plants, and are often very selective about their hosts. Despite extensive testing of related plants, dyer's woad is the only known plant host for this rust. When used according to label directions, pesticide products containing dyer's woad rust present no known risks to humans, non-target plants, wildlife, or the environment.

 

Isatis tinctoria (dyer's woad) http://en.wikipedia.org/wiki/Isatis_tinctoria


Via Kamoun Lab @ TSL
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Veterinary E-Books: Veterinary Microbiology and Microbial Diseases

Veterinary E-Books: Veterinary Microbiology and Microbial Diseases | mikrobiologija | Scoop.it
This is a core textbook covering every aspect of veterinary microbiology for students in both paraclinical and clinical years. The clinical applications to farm and companion animals, which are of relevance to the veterinarians are emphasised.
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Using viruses to beat superbugs #sgmdub

Using viruses to beat superbugs #sgmdub | mikrobiologija | Scoop.it

Viruses that can target and destroy bacteria have the potential to be an effective strategy for tackling hard-to-treat bacterial infections. The development of such novel therapies is being accelerated in response to growing antibiotic resistance, says Dr David Harper at the Society for General Microbiology's Spring Conference in Dublin.


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FOOD TECHNOLOGIST's curator insight, June 22, 2013 10:09 PM

Using viruses to beat superbugs

Rescooped by Franc Viktor Nekrep from The Microbiology Mine
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Predicting ‘airborne’ influenza viruses: (trans-) mission impossible? 10.1016/j.coviro.2011.07.003 : Current Opinion in Virology | ScienceDirect.com

Predicting ‘airborne’ influenza viruses: (trans-) mission impossible? 10.1016/j.coviro.2011.07.003 : Current Opinion in Virology | ScienceDirect.com | mikrobiologija | Scoop.it

EM Sorrell, EJA Schrauwen, M Linster, M De Graaf, S Herfst, RAM Fouchier,

 

http://dx.doi.org/10.1016/j.coviro.2011.07.003

 

Repeated transmission of animal influenza viruses to humans has prompted investigation of the viral, host, and environmental factors responsible for transmission via aerosols or respiratory droplets. How do we determine — out of thousands of influenza virus isolates collected in animal surveillance studies each year — which viruses have the potential to become ‘airborne’, and hence pose a pandemic threat? Here, using knowledge from pandemic, zoonotic and epidemic viruses, we postulate that the minimal requirements for efficient transmission of an animal influenza virus between humans are: efficient virus attachment to (upper) respiratory tissues, replication to high titers in these tissues, and release and aerosolization of single virus particles. Investigating ‘airborne’ transmission of influenza viruses is key to understand — and predict — influenza pandemics.

 


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Rescooped by Franc Viktor Nekrep from Viruses, Immunology & Bioinformatics from Virology.uvic.ca
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Nature News Blog: Hot spring yields hybrid genome : Nature News Blog

Nature News Blog: Hot spring yields hybrid genome : Nature News Blog | mikrobiologija | Scoop.it
In the hostile environment of a bubbling volcanic hot spring, a team of researchers at Portland State University (PSU) in Oregon has discovered a new viral genome that appears to be the product of recombination between a DNA virus and an RNA virus...

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Students Look to Unravel the Complexities of Chagas Disease

Students Look to Unravel the Complexities of Chagas Disease | mikrobiologija | Scoop.it

Chagas disease affects an estimated 8 to 11 million people worldwide. It is caused by a parasite transmitted primarily through a bite from the triatomine, or “kissing” bug — so-called because it frequently bites humans on the face.

 

Via @TweetNTD


Via Cesar Sanchez
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Current Opinion in Virology - Rinderpest eradication: lessons for measles eradication?

Current Opinion in Virology - Rinderpest eradication: lessons for measles eradication? | mikrobiologija | Scoop.it

In 2011 the Food and Agriculture Organization formally announced that rinderpest was eradicated from the globe. Rinderpest virus had long been associated with huge disease outbreaks among cattle.


Via Chris Upton + helpers
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New insights into ancient life: Chromosome segregation in Archaea

New insights into ancient life: Chromosome segregation in Archaea | mikrobiologija | Scoop.it
(PhysOrg.com) -- The effort to classify life into various groups has been a bumpy ride. Prior to the 1900s, living things were usually pegged as either plants or animals – period.
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Rescooped by Franc Viktor Nekrep from Virology News
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US biosecurity board revises stance on mutant-flu studies

US biosecurity board revises stance on mutant-flu studies | mikrobiologija | Scoop.it
Nature | Breaking News

 

The US National Science Advisory Board for Biosecurity (NSABB) today recommended the publication of two controversial avian flu papers.

In December 2011, the board said that experimental details of the two studies should be redacted from any publications because of concerns that the information could be used in a bioterror attack. The board also feared that publishing the details would prompt more laboratories to work on the viruses, making an accidental release more likely.

New guidelines aim to prevent concerns about dual use being raised only at the eve of publication.

CDC/ Taronna Maines

Today, after a two-day meeting, the board decided to revise its earlier decision.

 

Viva!!


Via Ed Rybicki
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Synthetic Biology: A New Approach to Science

Synthetic Biology: A New Approach to Science | mikrobiologija | Scoop.it

Via Gerd Moe-Behrens
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Synthetic in vitro circuits

by

Hockenberry AJ, Jewett MC.

"Inspired by advances in the ability to construct programmable circuits in living organisms, in vitro circuits are emerging as a viable platform for designing, understanding, and exploiting dynamic biochemical circuitry. In vitro systems allow researchers to directly access and manipulate biomolecular parts without the unwieldy complexity and intertwined dependencies that often exist in vivo. Experimental and computational foundations in DNA, DNA/RNA, and DNA/RNA/protein based circuitry have given rise to systems with more than 100 programmed molecular constituents. Functionally, they have diverse capabilities including: complex mathematical calculations, associative memory tasks, and sensing of small molecules. Progress in this field is showing that cell-free synthetic biology is a versatile testing ground for understanding native biological circuits and engineering novel functionality."


Via Gerd Moe-Behrens
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Rescooped by Franc Viktor Nekrep from Microbiologie
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Les propriétés antibiotiques du miel

Les propriétés antibiotiques du miel | mikrobiologija | Scoop.it

"C’est depuis l’Antiquité que les médecins et guérisseurs connaissent les effets antibactériens du miel. Toutefois, il aura fallu quelques millénaires pour identifier la molécule clé associée à ses propriétés antibiotiques, la " Défensine ".

Produit par les abeilles à partir du nectar des fleurs qu’elles butinent, le miel possède des propriétés curatives que les Grecs et les Romains utilisaient pour soigner les blessures, infections et problèmes digestifs. Malgré des recherches scientifiques qui ont pu montrer que le miel possédait effectivement des propriétés antibiotiques, ce n’est qu’en 2010 que son mécanisme d’action a été élucidé."

 

Autre document : http://www2.vetagro-sup.fr/bib/fondoc/th_sout/dl.php?file=2011lyon093.pdf

 


Via Damien Steiner
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Damien Steiner's comment, June 2, 2012 1:06 PM
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Major players on the microbial stage: why archaea are important

RT @Profmicro: Nice overview!RT @Archaellum: Why #archaea are important http://t.co/bVVH3W0G...
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Bacteria may help build PCs

Bacteria may help build PCs | mikrobiologija | Scoop.it

Magnet-making bacteria may help build biological computers of the future, an international team of researchers says.


Via Gerd Moe-Behrens
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From Soil Microbe to Super-Efficient Biofuel Factory? « Berkeley Lab News Center

From Soil Microbe to Super-Efficient Biofuel Factory? « Berkeley Lab News Center | mikrobiologija | Scoop.it

"Is there a new path to biofuels hiding in a handful of dirt? Lawrence Berkeley National Laboratory (Berkeley Lab) biologist Steve Singer leads a group that wants to find out. They’re exploring whether a common soil bacterium can be engineered to produce liquid transportation fuels much more efficiently than the ways in which advanced biofuels are made today.

The scientists are working with a bacterium called Ralstonia eutropha. It naturally uses hydrogen as an energy source to convert CO2 into various organic compounds.

The group hopes to capitalize on the bacteria’s capabilities and tweak it to produce advanced biofuels that are drop-in replacements for diesel and jet fuel. The process would be powered only by hydrogen and electricity from renewable sources such as solar or wind.

The goal is a biofuel—or electrofuel, as this new approach is called—that doesn’t require photosynthesis...."


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RNA studies under fire

RNA studies under fire | mikrobiologija | Scoop.it

High-throughput RNA sequencing has yielded some unexpected results in the past few years — including some that seem to rewrite conventional wisdom in genetics. But a few of those findings are now being challenged, as computational biologists warn of the statistical pitfalls that can lurk in data-intensive studies.


Via Mohamed Nadhir Djekidel, Chris Upton + helpers
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Algae-based Biofuel: Pros And Cons - Triple Pundit

Algae-based Biofuel: Pros And Cons - Triple Pundit | mikrobiologija | Scoop.it

Algae–based biofuel is a new energy source that has been getting a lot of attention lately.


Via Marko Dolinar
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Rescooped by Franc Viktor Nekrep from Microbiologie
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5 millions d'euros pour Enterome et sa technologie unique de métagénomique bactérienne

"L'intestin humain renferme des milliards de bactéries. Ce microbiote, c'est le nom qu'on lui donne, compte 150 fois plus gènes que le génome humain. Il faut savoir que chaque individu possède un microbiote unique et qu'il existe d'importantes diversités entre chaque personne. Au cours de ces dernières années, chercheurs et médecins ont prouvé l'incontestable rôle joué par ce microbiote intestinal dans le développement de nombreuses maladies, principalement les pathologies métaboliques chroniques et les maladies inflammatoires intestinales, des maladies qui affectent entre 25 et 40% de la population occidentale. Par exemple, la stéato-hépatite non alcoolique (SHNA), qui est la forme la plus sévère de l'une de ces maladies, est diagnostiquée chez 2 à 3% de la population mondiale."


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Nature: Fear of Fungi

Nature: Fear of Fungi | mikrobiologija | Scoop.it

One of few surviving southern mountain yellow-legged frogs (Rana muscosa) in Kings Canyon National Park, California, where chytrid fungus has all but wiped them out. Fungal infections have caused widespread damage in crops and dramatic declines in populations of amphibians and bat species. Newly emerged pathogenic fungi have been reported in corals, bees and many plants. In a Review this week, Matthew Fisher and colleagues warn that human activity is intensifying fungal disease dispersal by modifying natural ecosystems and creating new opportunities for evolution. Unless steps are taken to reduce the risk of these infectious diseases spreading globally, the authors suggest, fungal infections will cause increasing attrition of biodiversity, with wider implications for human and ecosystem health. The authors' recommendations include better monitoring of emerging diseases, stringent biosecurity controls on international trade and intensified research on the interactions between hosts, pathogens and the environment.

 

Check the publication at http://www.nature.com/nature/journal/v484/n7393/full/nature10947.html


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“hygiene hypothesis” gains support « Florida Biotechnology News

“hygiene hypothesis” gains support « Florida Biotechnology News | mikrobiologija | Scoop.it
The researchers studied the immune system of mice lacking bacteria or any other microbes (“germ-free mice”) and compared them to mice living in a normal environment with microbes. They found that germ-free mice had ...
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