Multimodal Approach Appears Promising for Treatment of Cancer Cachexia | Melanoma Dispatch |

"Cancer cachexia is a complex, multifactorial metabolic syndrome characterized by weight and muscle loss with or without loss of fat mass.

"It occurs in 30% to 80% of patients with cancer, and it is identified as an independent predictor of shorter survival and increased risk for treatment failure and toxicity...

"Due to the lack of selectivity of anabolic androgens, a need for more selective anabolic agents has emerged, resulting in the development of nonsteroidal selective androgen receptor modulators (SARMs). These agents have the potential to elicit beneficial anabolic effects while avoiding many of the side effects observed with steroidal agents."