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The five trademarks of agile organizations | McKinsey

From www.mckinsey.com

Agile organizations--of any size and across industries--have five key elements in common.
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Novartis and Uni of Oxford to join forces and use AI for diseases and drug development

From www.pharmatimes.com

Novartis and the University of Oxford’s Big Data Institute have announced that they are to establish a five-year research alliance using artificial intelligence to understand complex diseases and improve drug development.

The alliance plans to analyse huge data sets using artificial intelligence and machine learning to spot disease insights that have been undetectable to scientists thus far, expecting to transform how ultra large and multiple datasets are analysed, combined and interpreted to identify early predictors of patient responses to treatments for inflammatory diseases, such as multiple sclerosis (MS) and psoriasis.

The alliance will draw on data from around 5 million patients from the UK and international partner organisations, together with anonymised data captured from relevant Novartis clinical trials.

Using the BDI’s latest statistical machine learning technology and experience in data analysis, combined with Novartis’ wealth of clinical expertise and clinical trial data, the alliance expects to predict how patients will respond to existing and new medicines.

“Our collaboration with Novartis will enable both organisations to transform the scale and efficiency of clinical research at an unprecedented rate though the sharing of data, technology, and advanced analytics expertise” said Professor Gil McVean, director of the Big Data Institute.

“The BDI enables people and projects to span traditional boundaries and scientific disciplines, and leverage technological innovation for the benefit of patients.”
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L'edge computing, un outil incontournable dans l'industrie 4.0 #esante #hcsmeufr

From www.journaldunet.com

Sécurité renforcée, gains économiques, faible latence… Les avantages qu'offre l'edge computing permettent des déploiements dans la maintenance prédictive.
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How to Win at Clinical Trial Recruitment in 2019 – #esante #hcsmeufr #digitalhealth

From tincture.io

There are so many theories on how to improve clinical trial recruitment. There are endless panels, discussions, conferences, webinars, press releases, white papers, and interviews on how to improve clinical trial recruitment and success. The majority of these recommendations miss the mark completely. Is your 2019 goal to improve clinical trial recruitment?Here’s what you need to do from a patient and carepartner’s perspective to fundamentally improve clinical trial recruitment and your trial’s lifecycle and success:

 
  1. Include patients and carepartners in the ideation and design of the clinical trial lifecycle.

This is a must, not a nice to have. This is solid business strategy, not a marketing tactic or buzzword. You can’t afford to not get a trial right the first time or not fill your trial. Until you have patients and carepartners partnering with your company throughout the clinical trial lifecycle, interacting with every department of your company, you have haven’t overturned every stone. While you’re at it, stop using the words “patient-centered”.

2. Prioritize running patient advisory boards as essential think tanks for a healthy exchange of experiential learnings.

Speak to every single patient who completes their trial and ask for their insights and expertise immediately. Even better, ask for their insights and expertise throughout the trial. Don’t just speak to people who have participated and successfully completed clinical trials. Welcome those who didn’t qualify due to exclusion criteria. Seek the voices of those who faced too many social determinants of health barriers that made participation unfeasible. Invite those who mistrust the clinical trial process. Listen to the carepartners who did everything in their power to support their loved ones’ participation in a trial and yet they still dropped out, suffered immensely, or died. Invite the young adults who are the primary carepartners for their loved ones due to language barriers and cultural circumstances.

These are the real-world experiences and lives you need to intersect with. It’s going to be uncomfortable. Embrace it. It will be worth it and will change and inspire you. Pro-tip for the record: AI is not going to help you with this.

3. Stop looking for volunteers to simply fill your quotas. You need to start looking for research partners.

Clinical trials are a commitment and a profound sacrifice. Many patients strongly express that they want to be proactive in advancing science and medicine. Welcome people to sign up for trials as your research partners.

By shifting the lens from volunteer to research partner, the entire perspective as to meaning of the relationship, the sanctity of the commitment, and the importance of the work takes an entirely different perspective from both sides. Forge a trusted, longitudinal research partnership and many downstream challenges, such as adherence and retention, can be managed proactively vs in a back-peddling manner, or worse, an incomplete trial that can’t fulfill statistical significance (AKA millions upon millions of dollars lost and potential life-saving treatments never coming to market).

4. Budget to cover ALL expenses of participating in a trial.

Financial toxicity is a significant barrier to access. Participating in clinical trials does not come without expenses. Many physicians, let alone patients, are shocked to find out that certain tests and requirements of the trial are the patient’s responsibility. There must also be considerations for travel, time lost from work, childcare, elder care, hospital visits and admissions due to treatment side effects, hotels accommodations or even temporary housing. Make addressing financial toxicity a priority.

The money is there, it’s the priorities that need alignment with what brings value to patients. Still struggling to come up with funding to cover these expenses? Find ways to leverage technology to bring trials to patients. Or there’s always those massive marketing budgets that you could dip into.

5. Invite patients and carepartners to visit your company. Have them speak with members of your compliance, regulatory, finance, marketing, leadership, and scientific research teams regularly.

When’s the last time any of these teams spoke with a patient or carepartner? Internal teams need to hear first-hand the stories of success and failure and understand all the barriers to participation. Patient advocacy and engagement teams may already be regularly working with patients. It needs to be bigger, company-wide. You’re either all in or you’re not.

Clinical trial success depends on the entire company. Pharma’s internal culture needs a landslide change. Listening to patient and carepartner stories is inspirational for the people who are graced to hear their words. Welcoming patients and their loved ones to your company is an exceptional opportunity to build empathy, bring joy, connection, and instill a sense of purpose to your work environment. Patients and carepartners often state that being welcomed to tell their story and share their experiences and expertise to be healing and empowering.

This is a win-win and more powerful than any commercial or marketing tactic you have in your projected pipeline.

6. Leverage social media to bring your clinical trials to the forefront.

 

Use social media platforms as ways to educate the general public about clinical trials, dispel myths, amplify the benefits of participating in clinical trials. Be the pioneers in sending the message that your company isn’t just looking for volunteers, you are looking for research partners to advance science and medicine. Be strategic and savvy about hashtags! Peer-to-peer patient and carepartner support groups, patient leaders, and advocates spread credible content and messages about cutting-edge research throughout their communities at lighting speed and virally.

Pharma must conquer its fear of social media. Meet patients where they are.

7. Provide digital tools for clinical trial exploration and matching to be offered at point of care (POC) for patients and doctors to use.

Many physicians state they do not have an easy way to search for clinical trials that may be of interest for a particular patient. If they can’t look it up quickly while talking to a patient, they sure as heck aren’t going to discuss it as a treatment option. Remove the barriers by leveraging technology NOW!

Patients and their loved ones often spend hours in waiting rooms and exam rooms with nothing to do. Having access to a digital tool and a simple chatbot for clinical trial exploration and matching based on diagnoses, genetic mutations, basic demographics, and geographic locations would connect patients with the opportunities currently available.

This needs to become a mainstream part of preparing patients for their appointments, especially for those diagnosed with chronic illnesses and cancer.

8. Dispel myths associated with trials at a health literacy people can understand.

Emphasize the high caliber of care & support people receive during a trial. Highlight positive patient and carepartner stories in a culturally sensitive manner. There’s a great deal of good that is being done on the frontlines to improve the clinical trial process! There are success stories and strides being made.

There are so many good people who work in pharma and are dedicated to literally saving people’s lives. We need to do a better job of communicating that dedication and passion to the general public, to patients, carepartners, our colleagues in medicine, and within the walls of your companies.

9. Work to update treatment guidelines to encourage discussion of clinical trials as a treatment option earlier in treatment planning. Clinical trials should not be a last resort.

When all treatment options have failed, many patients are devastated to learn that they do not qualify for trials because they have been treated with too many other therapies or are too sick. Have you ever heard a patient say they wish they knew about clinical trials earlier because now it’s too late? Hearing that literally knocks the wind out of you and is soul-crushing.

No patient should ever feel like they missed their opportunity. Patients have a right to be informed about all treatment options, including clinical trials. Physicians must have the tools they need to seamlessly include discussions on clinical trials at POC and patients and carepartners need to be able to proactively explore trials. They won’t and can’t participate in something they don’t know about.

10. Try signing up for your own trial.

Go through every step of the process. Bonus points if you can get through a search on clinicaltrials.gov and get in touch with a human being using the contact number listed. Travel to the clinical trial site. Acquire your medical records in preparation for your intake appointment. Book a flight, hotel, find public transportation or take an Uber or Lyft to the enrollment site. Try finding the building, suite, and office. Review the consent forms.

Would you agree to 5 spinal taps, endless bloodwork, poorly coordinated care, no access to your medical records, out-of-pocket responsibilities for imaging, and no access to digital technologies or telemedicine? Does this sound exhausting, frustrating, or leave you outraged? You have some homework to do. Go back to step 1.

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Seul 20% des entreprises biopharmaceutiques sont matures sur le plan numérique (Etude)

From www.numerikare.be

Les entreprises biopharmaceutiques en Belgique sont à la traîne par rapport à celles des États-Unis et d’autres pays européens. C'est ce que démontre la Digital Business Global Executive Study 2018 Deloitte/MIT.
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In 2018, FDA approved an all-time record of 62 new therapeutic drugs (NTDs) [Not including diagnostic imaging agents, included are combination products with at least one new molecular entity as an ...

From pharmaceuticalintelligence.com

In 2018, FDA approved an all-time record of 62 new therapeutic drugs (NTDs) [Not including diagnostic imaging agents, included are combination products with at least one new molecular entity as an active ingredient] with average Peak Sales per NTD $1.2Billion.
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Le succès des hackathons ne faiblit pas #esante #hcsmeufr

From www.maddyness.com

Les hackathons, rassemblements de plusieurs jours pour collaborer sur des sujets de programmation, se multiplient d’année en année. Qu’ils soient internes ou externes, il suscitent un intérêt grandissant. Mais comment le phénomène a-il évolué ? Qui sont les profils sélectionnés ?
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IA et emploi en santé : quoi de neuf docteur ? #esante #hcsmeufr

From www.institutmontaigne.org

Nos propositions pour anticiper les effets de l'intelligence artificielle sur les métiers de la santé.
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CES 2019: Posos fait appel à l'IA pour répondre aux questions sur les médicaments #esante #hcsmeufr

From www.ticpharma.com

LAS VEGAS (Nevada) (TICpharma) - Créée il y a tout juste un an, la start-up française Posos a présenté au Consumer Electronics Show (CES), qui s'est déroulé du 8 au 11 janvier, un outil faisant appel à l'intelligence artificielle (IA) pour répondre aux questions des professionnels de santé sur les médicaments.


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Quelles compétences développer dans une économie moderne ?, Efficacité personnelle 

From business.lesechos.fr

Dans une société où l'information est un moteur de l'économie, les compétences nécessaires à la performance ont changé. Elles sont, avant tout, cognitives.
Nous vivons aujourd'hui dans une société de l'information
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85% du display sera programmatique en France en 2020 d’après eMarketer | Offremedia #esante #hcsmeufr 

From www.offremedia.com

Entre 2018 et 2020, en France, les dépenses en display programmatiques progresseront de +31% pour atteindre 1,37 Md€ et cela représente 85% du total display. Le volume investi est plus de 3 fois moins important qu’au Royaume-Uni qui dépasse les 6 Md€ en 2020, +41% de progression en 2 ans et près de 90% du display.
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5 Digital Trends You Need To Know To Stay Ahead Of The Medical Marketing Curve In 2019 [Infographic] – #esante #hcsmeufr #digitalhealth

From hcsmmonitor.com

To succeed on social media, it’s essential to stay ahead of the curve and understand the latest social media trends.

I’ve just published my annual social media marketing predictions for 2019. In it I’ve identified 14 major trends that should claim marketers’ focus in the new year.

It’s a lengthy post but if you’re serious about marketing your medical practice online in 2019, I highly recommend you take some time to read it over the coming days.

Below I’ve highlighted five of these trends which I think will have particular relevance to medical marketing.

Stella Chrysaki's curator insight, January 17, 11:49 AM
Top 5 digital trends you need to know about #marketing #digital #influencemarketing #contentisking

What Can Pharma Expect in 2019? #esante #digitalhealth #hcsmeufr

From social.eyeforpharma.com

For those of us that use the Gregorian calendar, this time of year is one for reflection. We look back at the year just gone and forward to the year to come and, armed with a list of best-self resolutions, we step into January full of hope and intention. Like most years, 2018 was a busy one for the pharmaceutical industry – best characterized perhaps not as a year of radical change but as 12 months of under-the-surface action. (But if you disagree, please do let me know).
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Démographie médicale et projet de loi "Ma santé 2022" | Conseil National de l'Ordre des Médecins

From www.conseil-national.medecin.fr

Le Conseil national de l’Ordre des médecins publie aujourd’hui l’Atlas 2018 de la démographie médicale.
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Le diplôme "santé connectée" de l'AP-HP fait le plein pour une deuxième année

From www.ticsante.com

Le diplôme "santé connectée" de l'AP-HP fait le plein pour une deuxième année
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La moitié des étudiants en médecine auront fait un burn out avant l'internat

From www.egora.fr

La moitié des étudiants en médecine auront fait un burn out avant l'internat
Par A. M. le 16-11-2018

C'est ce qui ressort d'une méta-analyse portant sur 17 431 carabins de 23 pays, effectuée par des chercheurs en psychiatrie français. Plus de 8000 d'entre eux ont souffert d'épuisement professionnel entre leur 1ère et leur 6ème année.
 

En 1903, un éditorial de la JAMA intitulé "Les suicides de médecins et leurs raisons" alertait sur le suicide chez les médecins aux États-Unis. Un siècle plus tard, cela "reste un problème majeur de santé publique", relèvent les auteurs de cette méta-analyse franco-québécoise, publiée dans la revue Psychiatrie européenne. Selon une méta-analyse de 2004, le taux de suicide était de 1,41 chez les médecins de sexe masculin et de 2,27 chez les femmes médecins, par rapport à la population générale.
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Preparing The Healthcare Workforce To Deliver A Digital Future

From www.forbes.com

1,226 viewsNov 9, 2018, 08:32am
Preparing The Healthcare Workforce To Deliver A Digital Future
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Which doctors are early adopters of emerging healthcare technologies? | Kantar Media

From www.kantarmedia.com

A variety of emerging technologies from smart speakers to virtual/augmented reality to wearable devices are expected to change the way healthcare services are delivered. According to Kantar Media’s 2018 Digital Insights Study, 1 out of 4 doctors surveyed indicate they already use one or more of the healthcare technologies measured.
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Doctors are asking technologists to shadow them before they build apps

From www.cnbc.com

Doctors have had enough with software that's not useful, so they're inviting entrepreneurs to shadow them.
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Profils numériques : la guerre est déclarée - ZDNet

From www.zdnet.fr

Selon le baromètre Expectra, les salaires des cadres français s'envolent. Et la "digitalisation" des entreprises "renforce encore ce phénomène". Les profils orientés numériques, jugés rares, sont ainsi très convoités, alimentant "la guerre des talent et ouvrant la voie à une surenchère des salaires."
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Près des trois quarts des professionnels de santé s'estiment "mal formés" sur le numérique (sondage)

From www.ticsante.com

POITIERS, 17 décembre 2018 (TICsanté) - Près des trois quarts des professionnels de santé (73%) s'estiment "mal formés" en matière de numérique, selon les résultats d'une étude réalisée par Odoxa pour l'Université numérique en santé et en sport (Uness), les universités de santé et la conférence des doyens de médecine, dévoilés le 13 décembre lors des 16e Assises nationales hospitalo-universitaires.
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Why Doctors Need More Technical Skills than Ever Before

From www.inc.com

Doctors are businesspeople as much as they are doctors. Like it or not, the US healthcare system is a constant dogfight.
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