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Ancient Civilizations, Fallen Angels And Free Energy Conference ...

Ancient Civilizations, Fallen Angels And Free Energy Conference ... | iFindIntersting | Scoop.it
Michael discusses the massive stone "rings" system discovered through out South Africa. He goes on to give his theory of what they are and what they were used for. If you like ancient mysterious, you need to watch this.
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Rescooped by Josh Chrisohoou from #PsychedelicMedicines
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Mapping the Psychedelic Brain

Mapping the Psychedelic Brain | iFindIntersting | Scoop.it
Active ingredient in magic mushrooms disrupts communication between brain regions

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Ketamine May Offer Rapid Relief From OCD Symptoms

Ketamine May Offer Rapid Relief From OCD Symptoms | iFindIntersting | Scoop.it
A small, randomized study suggests that patients with severe OCD can have rapid relief of their symptoms, lasting for at least a week, after receiving a single infusion of ketamine.

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Mangu TV's curator insight, December 10, 2013 4:57 AM

Interesting, we might have to add Ketamine to the list for Neurons to Nirvana part 2 (other candidates: iboga & DMT)

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300 DMT Trips Assembled into One Word Cloud

300 DMT Trips Assembled into One Word Cloud | iFindIntersting | Scoop.it
The text of 300 trip reports with the insanely potent psychedelic DMT were fed into a word cloud generator to produce this fascinating image

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An Overview of the Endocannabinoid System ... - Cannabis Journal

An Overview of the Endocannabinoid System ... - Cannabis Journal | iFindIntersting | Scoop.it
The following is a collection of research literature, resources, documentaries, interviews, and lecture clippings regarding the Endocannabinoid System and Cannabinoids contained in cannabis. The material below explains ...

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Mangu TV's curator insight, December 23, 2013 12:45 PM

How cannabis cures certain diseases.

#psychedelicmedicines

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Computational simulations of photosystem II exposes secret pathways behind photosynthesis

Computational simulations of photosystem II exposes secret pathways behind photosynthesis | iFindIntersting | Scoop.it
New insights into the behavior of photosynthetic proteins from atomic simulations could hasten the development of artificial light-gathering machines.

 

The protein complex known as photosystem II splits water molecules to release oxygen using sunlight and relatively simple biological building blocks. Although water can also be split artificially using an electrical voltage and a precious metal catalyst, researchers continue to strive to mimic the efficient natural process. So far, however, these efforts have been hampered by an incomplete understanding of the water oxidation mechanism of photosystem II. Shinichiro Nakamura from the RIKEN Innovation Center and colleagues have now used simulations to reveal the hidden pathways of water molecules inside photosystem II.


At the heart of photosystem II is a cluster of manganese, calcium and oxygen atoms, known as the oxygen-evolving complex (OEC), that catalyzes the water-splitting reaction. Recent high-resolution x-ray crystallography studies have revealed the precise positions of the atoms in the OEC and of the protein residues that contact the site. While this information has yielded important structural clues into photosynthetic water oxidation, the movements of water, oxygen and protons within the protein complex are still the subject of much speculation.

 

To resolve this problem, researchers have turned to molecular dynamics (MD) simulation, a technique that models the time-dependent behavior of biomolecules using thermodynamics and the physics of motion. While previous MD simulations of photosystem II have involved the use of approximate models that focus only on protein monomers or the main OEC components, Nakamura's team took a different approach. "Our hypothesis was that we cannot understand the mechanism of oxygen evolution just by looking at the manganese-based reaction center," he says. "Therefore, we carried out a total MD simulation, without any truncation of the protein or simplification."

 

In their simulation, the team embedded an exact model of photosystem II inside a thylakoid—a lipid and fatty-acid membrane-bound compartment found in the chloroplasts of plant cells. After initial computations confirmed the reliability of their model, the researchers performed a rigorous MD simulation of the protein—membrane system in the presence of more than 300,000 water molecules (Fig. 1). "The results indicated that water, oxygen and protons move through photosystem II not randomly but via distinct pathways that are not obviously visible," says Nakamura.

 

The pathways revealed by the simulations are delicately coupled to the dynamic motions of the photosystem II protein residues. While such intricate activity is currently impossible to reproduce artificially, the researchers suspect that combining quantum-chemical calculations with MD simulations could help to unlock the mysterious principles behind the highly efficient oxygen-evolution reactions of this remarkable biological factory.


Via Dr. Stefan Gruenwald
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LSD helps to treat alcoholism

LSD helps to treat alcoholism | iFindIntersting | Scoop.it
Retrospective analysis shows hallucinogenic drug helped problem drinkers.

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If You Haven't Heard Of DMT Yet, You Might Soon

If You Haven't Heard Of DMT Yet, You Might Soon | iFindIntersting | Scoop.it
Drug researchers have found evidence that a hallucinogenic compound used in shamanic rituals in the Amazon is growing in popularity.

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Psilocibina e Psiquiatria / Psilocybin and Psychiatry

Lecture from Robin Carhart-Harris, PhD (Imperial College London) on the effects of the psychedelics substance psilocybin on the human brain and mind. November 2013.


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Mangu TV's curator insight, December 17, 2013 4:16 AM

Don't be thrown of by the Brazilian language intro, the actual lecture is in English.  Very informative talk about psilocybin and the brain.

Rescooped by Josh Chrisohoou from #PsychedelicMedicines
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Ayahuasca Can Change Your Life -- As Long as Yo...

Ayahuasca Can Change Your Life -- As Long as Yo... | iFindIntersting | Scoop.it
Just before dusk, 18 strangers enter a yurt on a Midwestern homestead. Peruvian tapestries decorate the walls of the large, round structure, and rattles stand poised for a ceremony. The participants...

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Annett Culp - Meditation is the dissolution of thoughts in... | Facebook

Meditation is the dissolution of thoughts in Eternal awareness or Pure consciousness without objectification, knowing without thinking, merging finitude...
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